Published in Immunity on October 01, 2007
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Regulation of spontaneous intestinal tumorigenesis through the adaptor protein MyD88. Science (2007) 5.54
Toll-dependent selection of microbial antigens for presentation by dendritic cells. Nature (2006) 5.54
Intracellular localization of Toll-like receptor 9 prevents recognition of self DNA but facilitates access to viral DNA. Nat Immunol (2005) 4.30
Toll-like receptors and cancer. Nat Rev Cancer (2008) 4.29
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Cutting edge: MyD88 is required for resistance to Toxoplasma gondii infection and regulates parasite-induced IL-12 production by dendritic cells. J Immunol (2002) 3.12
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Interactions between the host innate immune system and microbes in inflammatory bowel disease. Gastroenterology (2011) 2.90
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The microbial metabolite butyrate regulates intestinal macrophage function via histone deacetylase inhibition. Proc Natl Acad Sci U S A (2014) 2.22
Age-associated defect in human TLR-1/2 function. J Immunol (2007) 2.20
NKG2D signaling is coupled to the interleukin 15 receptor signaling pathway. Nat Immunol (2007) 2.11
Triggering TLR signaling in vaccination. Trends Immunol (2005) 2.09
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Toll-like receptors and acquired immunity. Semin Immunol (2004) 1.79
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Host defense pathways: role of redundancy and compensation in infectious disease phenotypes. Immunity (2011) 1.57
Prevaccine determination of the expression of costimulatory B7 molecules in activated monocytes predicts influenza vaccine responses in young and older adults. J Infect Dis (2007) 1.56
Targeting of immune signalling networks by bacterial pathogens. Nat Cell Biol (2009) 1.52
The control of adaptive immune responses by the innate immune system. Adv Immunol (2011) 1.48
Influenza virus-induced glucocorticoids compromise innate host defense against a secondary bacterial infection. Cell Host Microbe (2010) 1.47
TLR4 up-regulation at protein or gene level is pathogenic for lupus-like autoimmune disease. J Immunol (2006) 1.44
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Signals via the adaptor MyD88 in B cells and DCs make distinct and synergistic contributions to immune activation and tissue damage in lupus. Immunity (2013) 1.40
Antiviral defense: interferons and beyond. J Exp Med (2006) 1.38
Integration of cytokine and heterologous receptor signaling pathways. Nat Immunol (2009) 1.36
Control of infection by pyroptosis and autophagy: role of TLR and NLR. Cell Mol Life Sci (2010) 1.35
Toll-like receptors: balancing host resistance with immune tolerance. Curr Opin Immunol (2003) 1.34
Semaphorin 7A is a negative regulator of T cell responses. Immunity (2006) 1.33
Adjuvants of immunity: harnessing innate immunity to promote adaptive immunity. J Exp Med (2002) 1.33
Abnormal trafficking and degradation of TLR4 underlie the elevated inflammatory response in cystic fibrosis. J Immunol (2011) 1.31
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Learning tolerance while fighting ignorance. Cell (2009) 1.20
Intrinsic sensor of oncogenic transformation induces a signal for innate immunosurveillance. Proc Natl Acad Sci U S A (2008) 1.20
A Yersinia effector with enhanced inhibitory activity on the NF-κB pathway activates the NLRP3/ASC/caspase-1 inflammasome in macrophages. PLoS Pathog (2011) 1.14
Immunostimulatory activity of haptenated proteins. Proc Natl Acad Sci U S A (2009) 1.10
Role of basophils in the initiation of Th2 responses. Curr Opin Immunol (2010) 1.10
Regulation of Toll-like receptor 4 expression in the lung following hemorrhagic shock and lipopolysaccharide. J Immunol (2002) 1.10
Airway epithelial MyD88 restores control of Pseudomonas aeruginosa murine infection via an IL-1-dependent pathway. J Immunol (2011) 1.08
Linking Toll-like receptors to IFN-alpha/beta expression. Nat Immunol (2003) 1.05
Innate sensors of microbial infection. J Clin Immunol (2005) 1.05
The human papillomavirus type 16 E7 oncoprotein induces a transcriptional repressor complex on the Toll-like receptor 9 promoter. J Exp Med (2013) 1.01
Two modes of ligand recognition by TLRs. Cell (2007) 0.99
Role of caspase-1 in regulation of triglyceride metabolism. Proc Natl Acad Sci U S A (2013) 0.97
Role of ITAM signaling module in signal integration. Curr Opin Immunol (2012) 0.94
Antifungal defense turns 17. Nat Immunol (2007) 0.93
Toll signaling: RIPping off the TNF pathway. Nat Immunol (2004) 0.90
Not so fast: adaptive suppression of innate immunity. Nat Med (2007) 0.89
Pyroptosis: macrophage suicide exposes hidden invaders. Curr Biol (2011) 0.89
A new shield for a cytokine storm. Cell (2011) 0.88
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Skin antibiotics get in the loop. Nat Med (2002) 0.84
The origins of tumor-promoting inflammation. Cancer Cell (2013) 0.84
Role of the inflammasome in defense against venoms. Proc Natl Acad Sci U S A (2013) 0.82
Fus1/Tusc2 is a novel regulator of mitochondrial calcium handling, Ca2+-coupled mitochondrial processes, and Ca2+-dependent NFAT and NF-κB pathways in CD4+ T cells. Antioxid Redox Signal (2014) 0.82
A plague on host defense. J Exp Med (2002) 0.81
Prostaglandin-secreting cells: a portable first aid kit for tissue repair. J Clin Invest (2007) 0.78
Training the next generation of biomedical investigators in glycosciences. J Clin Invest (2016) 0.76
Germs gone wild. Nat Med (2012) 0.75
Honor thy Go(na)ds. Immunol Cell Biol (2013) 0.75