Published in N Engl J Med on November 01, 2007
Managing incidental findings in human subjects research: analysis and recommendations. J Law Med Ethics (2008) 12.10
The Rotterdam Study: objectives and design update. Eur J Epidemiol (2007) 5.78
Epidemiology and etiology of meningioma. J Neurooncol (2010) 3.64
The Rotterdam Study: 2010 objectives and design update. Eur J Epidemiol (2009) 3.44
Incidental findings in imaging research: evaluating incidence, benefit, and burden. Arch Intern Med (2010) 3.40
The Rotterdam Study: 2012 objectives and design update. Eur J Epidemiol (2011) 3.26
Microinfarct pathology, dementia, and cognitive systems. Stroke (2011) 2.61
The Rotterdam Study: 2014 objectives and design update. Eur J Epidemiol (2013) 2.56
Neuroimaging in patients referred to a neuro-ophthalmology service: the rates of appropriateness and concordance in interpretation. Ophthalmology (2012) 2.05
Asymptomatic spinal cord lesions predict disease progression in radiologically isolated syndrome. Neurology (2011) 2.02
The law of incidental findings in human subjects research: establishing researchers' duties. J Law Med Ethics (2008) 1.84
Diffusion tensor imaging of cerebral white matter integrity in cognitive aging. Biochim Biophys Acta (2011) 1.74
Practical approaches to incidental findings in brain imaging research. Neurology (2008) 1.74
Retinal microvascular abnormalities and subclinical magnetic resonance imaging brain infarct: a prospective study. Brain (2010) 1.73
In vitro evaluation of the sinus sagittalis superior thrombosis model in the rat using 3D micro- and nanocomputed tomography. Neuroradiology (2009) 1.72
Communicating results in post-Belmont era biomonitoring studies: lessons from genetics and neuroimaging research. Environ Res (2014) 1.68
Mirror aneurysms: a reflection on natural history. J Neurosurg (2012) 1.67
Chiari type I malformation in a pediatric population. Pediatr Neurol (2009) 1.62
Subclinical left ventricular dysfunction and silent cerebrovascular disease: the Cardiovascular Abnormalities and Brain Lesions (CABL) study. Circulation (2013) 1.61
The Rotterdam Study: 2016 objectives and design update. Eur J Epidemiol (2015) 1.61
Carotid artery brain aneurysm model: in vivo molecular enzyme-specific MR imaging of active inflammation in a pilot study. Radiology (2009) 1.54
Headache, migraine, and structural brain lesions and function: population based Epidemiology of Vascular Ageing-MRI study. BMJ (2011) 1.51
Individual topographic variability is inherent to cortical physiology but task-related differences may be noise. PLoS One (2015) 1.39
Unruptured intracranial aneurysms: development, rupture and preventive management. Nat Rev Neurol (2016) 1.38
Neuropsychological improvement after posterior fossa arachnoid cyst drainage. Childs Nerv Syst (2016) 1.37
Impaired survival and long-term neurological problems in benign meningioma. Neuro Oncol (2012) 1.37
Mutations in 2 distinct genetic pathways result in cerebral cavernous malformations in mice. J Clin Invest (2011) 1.36
Inflammatory biomarkers of vascular risk as correlates of leukoariosis. Stroke (2009) 1.32
Phase-contrast magnetic resonance imaging measurements in intracranial aneurysms in vivo of flow patterns, velocity fields, and wall shear stress: comparison with computational fluid dynamics. Magn Reson Med (2009) 1.26
Radiologically isolated syndrome: 5-year risk for an initial clinical event. PLoS One (2014) 1.24
Loss of SUFU function in familial multiple meningioma. Am J Hum Genet (2012) 1.21
Introduction: the challenge of incidental findings. J Law Med Ethics (2008) 1.20
Incidental findings found in "healthy" volunteers during imaging performed for research: current legal and ethical implications. Br J Radiol (2010) 1.18
Association of serum soluble receptor for advanced glycation end-products with subclinical cerebrovascular disease: the Northern Manhattan Study (NOMAS). Atherosclerosis (2011) 1.17
Potentially relevant incidental findings on research whole-body MRI in the general adult population: frequencies and management. Eur Radiol (2012) 1.13
Localization of brain white matter hyperintensities and urinary incontinence in community-dwelling older adults. J Gerontol A Biol Sci Med Sci (2009) 1.09
LA volumes and reservoir function are associated with subclinical cerebrovascular disease: the CABL (Cardiovascular Abnormalities and Brain Lesions) study. JACC Cardiovasc Imaging (2013) 1.08
The Rotterdam Scan Study: design and update up to 2012. Eur J Epidemiol (2011) 1.07
The myth of the normal, average human brain--the ICBM experience: (1) subject screening and eligibility. Neuroimage (2008) 1.02
A practical approach to incidental findings in neuroimaging research. Neurology (2011) 1.02
Intracranial arachnoid cysts--do they impair mental functions? J Neurol (2008) 1.02
Update on meningiomas. Oncologist (2011) 0.99
Strategy for identifying repurposed drugs for the treatment of cerebral cavernous malformation. Circulation (2014) 0.98
Family and personal medical history and risk of meningioma. J Neurosurg (2011) 0.97
Psychosocial consequences and severity of disclosed incidental findings from whole-body MRI in a general population study. Eur Radiol (2012) 0.97
Microvascular lesions in the brain and retina: The age, gene/environment susceptibility-Reykjavik study. Ann Neurol (2009) 0.96
Incidental findings of brain magnetic resonance imaging study in a pediatric cohort in Japan and recommendation for a model management protocol. J Epidemiol (2010) 0.96
The impact of vascular burden on late-life depression. Brain Res Rev (2009) 0.94
Models that matter: white matter stroke models. Neurotherapeutics (2012) 0.93
Brain magnetic resonance imaging findings in Smith-Lemli-Opitz syndrome. Am J Med Genet A (2013) 0.93
Incidental findings on brain magnetic resonance imaging of children with sickle cell disease. Pediatrics (2010) 0.92
Hyperintense MRI lesions in bipolar disorder: A meta-analysis and review. Int Rev Psychiatry (2009) 0.92
Microarray-based gene expression profiling and DNA copy number variation analysis of temporal fossa arachnoid cysts. Cerebrospinal Fluid Res (2010) 0.90
Aneurysmal Subarachnoid Hemorrhage. J Neurosurg Anesthesiol (2015) 0.89
A system for addressing incidental findings in neuroimaging research. Neuroimage (2011) 0.89
Unruptured intracranial aneurysms in the Familial Intracranial Aneurysm and International Study of Unruptured Intracranial Aneurysms cohorts: differences in multiplicity and location. J Neurosurg (2012) 0.89
Lack of CCM1 induces hypersprouting and impairs response to flow. Hum Mol Genet (2014) 0.88
Incidental radiographic findings after injury: dedicated attention results in improved capture, documentation, and management. Surgery (2010) 0.88
Oligodendrogenesis in the normal and pathological central nervous system. Front Neurosci (2014) 0.87
Hunting for the causes of meningioma--obesity is a suspect. Cancer Prev Res (Phila) (2011) 0.87
Studying variability in human brain aging in a population-based German cohort-rationale and design of 1000BRAINS. Front Aging Neurosci (2014) 0.86
Arachnoid cysts do not contain cerebrospinal fluid: A comparative chemical analysis of arachnoid cyst fluid and cerebrospinal fluid in adults. Cerebrospinal Fluid Res (2010) 0.86
Intracranial meningiomas managed at Memfys hospital for neurosurgery in Enugu, Nigeria. J Neurosci Rural Pract (2012) 0.86
Prevalence and symptoms of intracranial arachnoid cysts: a population-based study. J Neurol (2016) 0.86
Incidence and evaluation of incidental abnormal bone marrow signal on magnetic resonance imaging. ScientificWorldJournal (2014) 0.85
A novel and generalizable organotypic slice platform to evaluate stem cell potential for targeting pediatric brain tumors. Cancer Cell Int (2008) 0.85
Arteriovenous malformations and other vascular malformation syndromes. Cold Spring Harb Perspect Med (2013) 0.85
Age of collagen in intracranial saccular aneurysms. Stroke (2014) 0.85
DNA microarray analysis identifies CKS2 and LEPR as potential markers of meningioma recurrence. Oncologist (2011) 0.85
Evaluation of the middle cerebral artery occlusion techniques in the rat by in-vitro 3-dimensional micro- and nano computed tomography. BMC Neurol (2010) 0.84
Non-contrast-enhanced whole-body magnetic resonance imaging in the general population: the incidence of abnormal findings in patients 50 years old and younger compared to older subjects. PLoS One (2014) 0.84
Adjuvant radiation therapy, local recurrence, and the need for salvage therapy in atypical meningioma. Neuro Oncol (2014) 0.83
Chiari malformation type I: a case-control association study of 58 developmental genes. PLoS One (2013) 0.83
Brain iron deposition in white matter hyperintensities: a 3-T MRI study. Age (Dordr) (2012) 0.83
Is the incidence of meningiomas underestimated? A regional survey. Br J Cancer (2008) 0.83
Cerebral aneurysms: formation, progression, and developmental chronology. Transl Stroke Res (2013) 0.83
Incidental findings on brain MR imaging in older community-dwelling subjects are common but serious medical consequences are rare: a cohort study. PLoS One (2013) 0.83
Stakeholder Opinions And Ethical Perspectives Support Complete Disclosure Of Incidental Findings In MRI Research. Ethics Behav (2014) 0.83
The Rotterdam Scan Study: design update 2016 and main findings. Eur J Epidemiol (2015) 0.83
A prognostic cytogenetic scoring system to guide the adjuvant management of patients with atypical meningioma. Neuro Oncol (2015) 0.83
Epidemiological investigation of 264 sporadic cases of ruptured cerebral aneurysm at a single institution in southwest China. Neuropsychiatr Dis Treat (2015) 0.82
Value of neuroimaging in epilepsy: An experience from Pakistan. J Neurosci Rural Pract (2013) 0.82
Prevalence of unruptured intracranial aneurysm on MR angiography. Korean J Radiol (2011) 0.82
Incidental cranial CT findings in head injury patients in a Nigerian tertiary hospital. J Emerg Trauma Shock (2015) 0.82
Systemic diagnostic testing in patients with apparently isolated uveal coloboma. Am J Ophthalmol (2013) 0.82
An MRI-based semiquantitative index for the evaluation of brain atrophy and lesions in Alzheimer's disease, mild cognitive impairment and normal aging. Dement Geriatr Cogn Disord (2010) 0.82
Intracranial arachnoid cysts: impairment of higher cognitive functions and postoperative improvement. J Neurodev Disord (2013) 0.82
Neuroimaging and other investigations in patients presenting with headache. Ann Indian Acad Neurol (2012) 0.81
White matter integrity in small vessel disease is related to cognition. Neuroimage Clin (2015) 0.81
Correlating lesion size and location to deficits after ischemic stroke: the influence of accounting for altered peri-necrotic tissue and incidental silent infarcts. Behav Brain Funct (2010) 0.81
Controversies in epidemiology of intracranial aneurysms and SAH. Nat Rev Neurol (2015) 0.81
Unruptured intracranial aneurysms and the Trial on Endovascular Aneurysm Management (TEAM): The principles behind the protocol. J Vasc Interv Neurol (2008) 0.81
[Meningioma of the anterior visual pathways. Epidemiology and clinical symptoms]. Ophthalmologe (2013) 0.80
Descriptive epidemiology of World Health Organization grades II and III intracranial meningiomas in the United States. Neuro Oncol (2015) 0.80
Unanticipated demyelinating pathology of the CNS. Nat Rev Neurol (2009) 0.80
Large pituitary incidentaloma in a patient with sarcoidosis. J Community Hosp Intern Med Perspect (2014) 0.80
Evolution of universal review and disclosure of MRI reports to research participants. Brain Behav (2016) 0.80
The 'Sphere': A Dedicated Bifurcation Aneurysm Flow-Diverter Device. Cardiovasc Eng Technol (2014) 0.80
Biological, clinical and population relevance of 95 loci for blood lipids. Nature (2010) 28.21
Association analyses of 249,796 individuals reveal 18 new loci associated with body mass index. Nat Genet (2010) 23.08
Six new loci associated with body mass index highlight a neuronal influence on body weight regulation. Nat Genet (2008) 22.35
Hundreds of variants clustered in genomic loci and biological pathways affect human height. Nature (2010) 20.01
A randomized trial of intraarterial treatment for acute ischemic stroke. N Engl J Med (2014) 18.12
New genetic loci implicated in fasting glucose homeostasis and their impact on type 2 diabetes risk. Nat Genet (2010) 17.89
Twelve type 2 diabetes susceptibility loci identified through large-scale association analysis. Nat Genet (2010) 16.96
Large-scale association analysis identifies 13 new susceptibility loci for coronary artery disease. Nat Genet (2011) 13.25
Genetic variants in novel pathways influence blood pressure and cardiovascular disease risk. Nature (2011) 13.25
Loci influencing lipid levels and coronary heart disease risk in 16 European population cohorts. Nat Genet (2008) 12.32
Genome-wide association study of blood pressure and hypertension. Nat Genet (2009) 11.54
Large-scale association analysis provides insights into the genetic architecture and pathophysiology of type 2 diabetes. Nat Genet (2012) 11.09
Variants in MTNR1B influence fasting glucose levels. Nat Genet (2008) 10.85
Silent brain infarcts and the risk of dementia and cognitive decline. N Engl J Med (2003) 10.61
Variant of TREM2 associated with the risk of Alzheimer's disease. N Engl J Med (2012) 10.16
Genome-wide analysis of genetic loci associated with Alzheimer disease. JAMA (2010) 9.52
Common variants at ABCA7, MS4A6A/MS4A4E, EPHA1, CD33 and CD2AP are associated with Alzheimer's disease. Nat Genet (2011) 9.23
Common genetic determinants of vitamin D insufficiency: a genome-wide association study. Lancet (2010) 8.89
Large-scale genotyping identifies 41 new loci associated with breast cancer risk. Nat Genet (2013) 8.24
Arterial stiffness and risk of coronary heart disease and stroke: the Rotterdam Study. Circulation (2006) 8.18
Epidemiology of Parkinson's disease. Lancet Neurol (2006) 8.13
Meta-analysis identifies 13 new loci associated with waist-hip ratio and reveals sexual dimorphism in the genetic basis of fat distribution. Nat Genet (2010) 7.94
Diagnostic accuracy of 64-slice computed tomography coronary angiography: a prospective, multicenter, multivendor study. J Am Coll Cardiol (2008) 7.56
Host polymorphisms in interleukin 4, complement factor H, and C-reactive protein associated with nasal carriage of Staphylococcus aureus and occurrence of boils. J Infect Dis (2008) 7.45
Sequence variants at CHRNB3-CHRNA6 and CYP2A6 affect smoking behavior. Nat Genet (2010) 6.49
C-reactive protein, fibrinogen, and cardiovascular disease prediction. N Engl J Med (2012) 6.39
Prevalence, incidence and lifetime risk of atrial fibrillation: the Rotterdam study. Eur Heart J (2006) 6.31
Association of three genetic loci with uric acid concentration and risk of gout: a genome-wide association study. Lancet (2008) 5.89
Genome-wide association scan meta-analysis identifies three Loci influencing adiposity and fat distribution. PLoS Genet (2009) 5.81
The Rotterdam Study: objectives and design update. Eur J Epidemiol (2007) 5.78
New loci associated with kidney function and chronic kidney disease. Nat Genet (2010) 5.58
Genome-wide meta-analysis identifies 56 bone mineral density loci and reveals 14 loci associated with risk of fracture. Nat Genet (2012) 5.48
Prolonged QTc interval and risk of sudden cardiac death in a population of older adults. J Am Coll Cardiol (2006) 5.39
Alcohol consumption and risk of dementia: the Rotterdam Study. Lancet (2002) 5.32
Twenty bone-mineral-density loci identified by large-scale meta-analysis of genome-wide association studies. Nat Genet (2009) 5.32
Genomewide association studies of stroke. N Engl J Med (2009) 5.29
Common variants at ten loci influence QT interval duration in the QTGEN Study. Nat Genet (2009) 5.20
Correlation between genetic and geographic structure in Europe. Curr Biol (2008) 5.02
The Study on Cognition and Prognosis in the Elderly (SCOPE): principal results of a randomized double-blind intervention trial. J Hypertens (2003) 4.91
Physical activity, including walking, and cognitive function in older women. JAMA (2004) 4.90
Multiple loci associated with indices of renal function and chronic kidney disease. Nat Genet (2009) 4.78
Silent brain infarcts and white matter lesions increase stroke risk in the general population: the Rotterdam Scan Study. Stroke (2003) 4.78
Plasma Abeta(1-40) and Abeta(1-42) and the risk of dementia: a prospective case-cohort study. Lancet Neurol (2006) 4.77
Large-scale association analyses identify new loci influencing glycemic traits and provide insight into the underlying biological pathways. Nat Genet (2012) 4.73
GWAS of 126,559 individuals identifies genetic variants associated with educational attainment. Science (2013) 4.71
High serum uric acid as a novel risk factor for type 2 diabetes. Diabetes Care (2007) 4.69
High-resolution spiral computed tomography coronary angiography in patients referred for diagnostic conventional coronary angiography. Circulation (2005) 4.68
Interleukin-6 receptor pathways in coronary heart disease: a collaborative meta-analysis of 82 studies. Lancet (2012) 4.63
Meta-analyses of genome-wide association studies identify multiple loci associated with pulmonary function. Nat Genet (2009) 4.56
Lipoprotein-associated phospholipase A(2) and risk of coronary disease, stroke, and mortality: collaborative analysis of 32 prospective studies. Lancet (2010) 4.46
Genome-wide association study identifies 19p13.3 (UNC13A) and 9p21.2 as susceptibility loci for sporadic amyotrophic lateral sclerosis. Nat Genet (2009) 4.38
A genome-wide approach accounting for body mass index identifies genetic variants influencing fasting glycemic traits and insulin resistance. Nat Genet (2012) 4.37
Multiple loci influence erythrocyte phenotypes in the CHARGE Consortium. Nat Genet (2009) 4.28
Meta-analysis of genome-wide scans for human adult stature identifies novel Loci and associations with measures of skeletal frame size. PLoS Genet (2009) 4.24
Genome-wide trans-ancestry meta-analysis provides insight into the genetic architecture of type 2 diabetes susceptibility. Nat Genet (2014) 4.13
Dietary intake of antioxidants and risk of Alzheimer disease. JAMA (2002) 4.01
Common variants in KCNN3 are associated with lone atrial fibrillation. Nat Genet (2010) 3.97
Physical activity attenuates the influence of FTO variants on obesity risk: a meta-analysis of 218,166 adults and 19,268 children. PLoS Med (2011) 3.94
Genetic risk factors for ischaemic stroke and its subtypes (the METASTROKE collaboration): a meta-analysis of genome-wide association studies. Lancet Neurol (2012) 3.93
Lipid-related markers and cardiovascular disease prediction. JAMA (2012) 3.91
Variants in ZFHX3 are associated with atrial fibrillation in individuals of European ancestry. Nat Genet (2009) 3.80
Genome-wide association study of PR interval. Nat Genet (2010) 3.73
Identification of common variants associated with human hippocampal and intracranial volumes. Nat Genet (2012) 3.73
Meta-analysis identifies six new susceptibility loci for atrial fibrillation. Nat Genet (2012) 3.71
Meta-analysis of genome-wide association studies in >80 000 subjects identifies multiple loci for C-reactive protein levels. Circulation (2011) 3.68
Common carotid intima-media thickness measurements in cardiovascular risk prediction: a meta-analysis. JAMA (2012) 3.67
Common variants in 22 loci are associated with QRS duration and cardiac ventricular conduction. Nat Genet (2010) 3.55
Predicting type 2 diabetes based on polymorphisms from genome-wide association studies: a population-based study. Diabetes (2008) 3.54
Quantifying the heart failure epidemic: prevalence, incidence rate, lifetime risk and prognosis of heart failure The Rotterdam Study. Eur Heart J (2004) 3.52
The Rotterdam Study: 2010 objectives and design update. Eur J Epidemiol (2009) 3.44
Genome-wide association study identifies six new loci influencing pulse pressure and mean arterial pressure. Nat Genet (2011) 3.40
Inflammatory proteins in plasma and the risk of dementia: the rotterdam study. Arch Neurol (2004) 3.38
Thirty new loci for age at menarche identified by a meta-analysis of genome-wide association studies. Nat Genet (2010) 3.37
New ischaemic brain lesions on MRI after stenting or endarterectomy for symptomatic carotid stenosis: a substudy of the International Carotid Stenting Study (ICSS). Lancet Neurol (2010) 3.35
Cerebral small-vessel disease and decline in information processing speed, executive function and memory. Brain (2005) 3.34
Homocysteine levels and the risk of osteoporotic fracture. N Engl J Med (2004) 3.32
Coronary calcification improves cardiovascular risk prediction in the elderly. Circulation (2005) 3.28
Corticosteroids and the risk of atrial fibrillation. Arch Intern Med (2006) 3.28
The Rotterdam Study: 2012 objectives and design update. Eur J Epidemiol (2011) 3.26
Genome-wide meta-analysis identifies 11 new loci for anthropometric traits and provides insights into genetic architecture. Nat Genet (2013) 3.25
Novel loci for adiponectin levels and their influence on type 2 diabetes and metabolic traits: a multi-ethnic meta-analysis of 45,891 individuals. PLoS Genet (2012) 3.21
Incidence and prognosis of transient neurological attacks. JAMA (2007) 3.21