Published in Nucleic Acids Res on November 08, 2007
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A forward genetic strategy reveals destabilizing mutations in the Ebolavirus glycoprotein that alter its protease dependence during cell entry. J Virol (2010) 1.87
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The omptins of Yersinia pestis and Salmonella enterica cleave the reactive center loop of plasminogen activator inhibitor 1. J Bacteriol (2010) 0.95
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Cell type-dependent pathogenic functions of overexpressed human cathepsin B in murine breast cancer progression. Oncogene (2013) 0.92
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Design of thermostable beta-propeller phytases with activity over a broad range of pHs and their overproduction by Pichia pastoris. Appl Environ Microbiol (2010) 0.91
Genome-wide survey of prokaryotic serine proteases: analysis of distribution and domain architectures of five serine protease families in prokaryotes. BMC Genomics (2008) 0.91
Conservation and divergence of ADAM family proteins in the Xenopus genome. BMC Evol Biol (2010) 0.91
Molecular recognition and regulation of human angiotensin-I converting enzyme (ACE) activity by natural inhibitory peptides. Sci Rep (2012) 0.91
The amyloid precursor protein/protease nexin 2 Kunitz inhibitor domain is a highly specific substrate of mesotrypsin. J Biol Chem (2009) 0.91
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The Rho GTPase inactivation domain in Vibrio cholerae MARTX toxin has a circularly permuted papain-like thiol protease fold. Proteins (2009) 0.90
The TSG-6/HC2-mediated transfer is a dynamic process shuffling heavy chains between glycosaminoglycans. J Biol Chem (2010) 0.90
Increased levels of a unique post-translationally modified betaIVb-tubulin isotype in liver cancer. Biochemistry (2008) 0.90
Crystal structure of the antimicrobial peptidase lysostaphin from Staphylococcus simulans. FEBS J (2014) 0.90
Developing novel anthelmintics from plant cysteine proteinases. Parasit Vectors (2008) 0.90
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The oligopeptidase B of Leishmania regulates parasite enolase and immune evasion. J Biol Chem (2010) 0.89
A family of diverse Kunitz inhibitors from Echinococcus granulosus potentially involved in host-parasite cross-talk. PLoS One (2009) 0.89
Identification and prioritization of novel uncharacterized peptidases for biochemical characterization. Database (Oxford) (2013) 0.89
Multimodal protein constructs for herbivore insect control. Toxins (Basel) (2012) 0.89
The genome of Spironucleus salmonicida highlights a fish pathogen adapted to fluctuating environments. PLoS Genet (2014) 0.89
Crystal and solution structures of a prokaryotic M16B peptidase: an open and shut case. Structure (2009) 0.88
A lead discovery strategy driven by a comprehensive analysis of proteases in the peptide substrate space. Protein Sci (2010) 0.88
An enriched structural kinase database to enable kinome-wide structure-based analyses and drug discovery. Protein Sci (2010) 0.88
The yeast HtrA orthologue Ynm3 is a protease with chaperone activity that aids survival under heat stress. Mol Biol Cell (2008) 0.88
Gingipain aminopeptidase activities in Porphyromonas gingivalis. Biol Chem (2012) 0.88
MUC1 is a substrate for gamma-secretase. J Cell Biochem (2009) 0.88
Toward stable genetic engineering of human O-glycosylation in plants. Plant Physiol (2012) 0.87
Functional and structural roles of the Cys14-Cys38 disulfide of bovine pancreatic trypsin inhibitor. J Mol Biol (2008) 0.87
Identification and characterization of a bacterial glutamic peptidase. BMC Biochem (2010) 0.86
Pepsin homologues in bacteria. BMC Genomics (2009) 0.86
Activation and proteolytic activity of the Treponema pallidum metalloprotease, pallilysin. PLoS Pathog (2012) 0.86
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Anti-staphylococcal activities of lysostaphin and LytM catalytic domain. BMC Microbiol (2012) 0.85
Versatile loops in mycocypins inhibit three protease families. J Biol Chem (2009) 0.85
Activity-based probes for rhomboid proteases discovered in a mass spectrometry-based assay. Proc Natl Acad Sci U S A (2013) 0.85
The maize cystatin CC9 interacts with apoplastic cysteine proteases. Plant Signal Behav (2012) 0.84
WebLogo: a sequence logo generator. Genome Res (2004) 59.58
MUSCLE: a multiple sequence alignment method with reduced time and space complexity. BMC Bioinformatics (2004) 50.89
Pfam: clans, web tools and services. Nucleic Acids Res (2006) 34.83
The Universal Protein Resource (UniProt): an expanding universe of protein information. Nucleic Acids Res (2006) 22.70
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COSMIC: mining complete cancer genomes in the Catalogue of Somatic Mutations in Cancer. Nucleic Acids Res (2010) 25.55
Discovery of a selective inhibitor of oncogenic B-Raf kinase with potent antimelanoma activity. Proc Natl Acad Sci U S A (2008) 17.41
Systematic sequencing of renal carcinoma reveals inactivation of histone modifying genes. Nature (2010) 14.50
Somatic mutations of the histone H3K27 demethylase gene UTX in human cancer. Nat Genet (2009) 10.21
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MEROPS: the database of proteolytic enzymes, their substrates and inhibitors. Nucleic Acids Res (2011) 4.90
An integrative approach for in silico glioma research. IEEE Trans Biomed Eng (2010) 4.55
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Data mining using the Catalogue of Somatic Mutations in Cancer BioMart. Database (Oxford) (2011) 2.84
Integrated morphologic analysis for the identification and characterization of disease subtypes. J Am Med Inform Assoc (2012) 2.68
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LET-99, GOA-1/GPA-16, and GPR-1/2 are required for aster-positioned cytokinesis. Curr Biol (2006) 1.91
Accelerating Large Scale Image Analyses on Parallel, CPU-GPU Equipped Systems. IPDPS (2012) 1.76
Chromosomal mobilization and reintegration of Sleeping Beauty and PiggyBac transposons. Genesis (2009) 1.68
The MEROPS batch BLAST: a tool to detect peptidases and their non-peptidase homologues in a genome. Biochimie (2007) 1.67
Efficient Irregular Wavefront Propagation Algorithms on Hybrid CPU-GPU Machines. Parallel Comput (2013) 1.62
Human dermal stem cells differentiate into functional epidermal melanocytes. J Cell Sci (2010) 1.48
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High-throughput Analysis of Large Microscopy Image Datasets on CPU-GPU Cluster Platforms. IPDPS (2013) 1.36
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The tumor microenvironment strongly impacts master transcriptional regulators and gene expression class of glioblastoma. Am J Pathol (2012) 1.25
Modeling the evolution of ETV6-RUNX1-induced B-cell precursor acute lymphoblastic leukemia in mice. Blood (2011) 1.16
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A 3D Primary Vessel Reconstruction Framework with Serial Microscopy Images. Med Image Comput Comput Assist Interv (2015) 0.96
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Using the MEROPS Database for Proteolytic Enzymes and Their Inhibitors and Substrates. Curr Protoc Bioinformatics (2014) 0.85
Pyroglutamyl-peptidase I: cloning, sequencing, and characterisation of the recombinant human enzyme. Protein Expr Purif (2003) 0.81
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