Published in Transl Res on August 15, 2007
p38 Mitogen-activated protein kinase (MAPK) increases arginase activity and contributes to endothelial dysfunction in corpora cavernosa from angiotensin-II-treated mice. J Sex Med (2010) 1.03
The IgA1 immune complex-mediated activation of the MAPK/ERK kinase pathway in mesangial cells is associated with glomerular damage in IgA nephropathy. Kidney Int (2012) 0.95
Mitogen-activated protein kinase-activated protein kinase 2 in angiotensin II-induced inflammation and hypertension: regulation of oxidative stress. Hypertension (2010) 0.94
Altered MAPK signaling in progressive deterioration of endothelial function in diabetic mice. Diabetes (2012) 0.89
Tissue-specific up-regulation of arginase I and II induced by p38 MAPK mediates endothelial dysfunction in type 1 diabetes mellitus. Br J Pharmacol (2015) 0.81
Emodin ameliorates high-glucose induced mesangial p38 over-activation and hypocontractility via activation of PPARgamma. Exp Mol Med (2009) 0.81
Raf-1 kinase regulates smooth muscle contraction in the rat mesenteric arteries. J Vasc Res (2010) 0.78
The Role of p38 MAPK in the Development of Diabetic Cardiomyopathy. Int J Mol Sci (2016) 0.75
Significant association between glycemic status and increased estimated postglomerular resistance in nondiabetic subjects - study of inulin and para-aminohippuric acid clearance in humans. Physiol Rep (2015) 0.75
A second generation human haplotype map of over 3.1 million SNPs. Nature (2007) 85.39
Genome-wide detection and characterization of positive selection in human populations. Nature (2007) 17.27
BOOST: A fast approach to detecting gene-gene interactions in genome-wide case-control studies. Am J Hum Genet (2010) 3.41
Topological structure analysis of the protein-protein interaction network in budding yeast. Nucleic Acids Res (2003) 2.90
Role of the microvascular endothelium in progressive renal disease. J Am Soc Nephrol (2002) 2.51
A high-density genetic recombination map of sequence-tagged sites for sorghum, as a framework for comparative structural and evolutionary genomics of tropical grains and grasses. Genetics (2003) 2.40
SNPHarvester: a filtering-based approach for detecting epistatic interactions in genome-wide association studies. Bioinformatics (2008) 1.85
High nitrogen supply and carbohydrate content reduce fungal endophyte and alkaloid concentration in Lolium perenne. New Phytol (2007) 1.81
Predictive rule inference for epistatic interaction detection in genome-wide association studies. Bioinformatics (2009) 1.45
The aging kidney: physiological changes. Adv Chronic Kidney Dis (2010) 1.42
Paradoxes of nitric oxide in the diabetic kidney. Am J Physiol Renal Physiol (2003) 1.38
Rescue of mesangial cells from high glucose-induced over-proliferation and extracellular matrix secretion by hydrogen sulfide. Nephrol Dial Transplant (2011) 1.24
Depot medroxyprogesterone acetate increases immune cell numbers and activation markers in human vaginal mucosal tissues. AIDS Res Hum Retroviruses (2012) 1.23
Renal expression of osmotically responsive cation channel TRPV4 is restricted to water-impermeant nephron segments. Am J Physiol Renal Physiol (2004) 1.23
Altered endothelial nitric oxide synthase targeting and conformation and caveolin-1 expression in the diabetic kidney. Diabetes (2006) 1.22
Ssh10b, a conserved thermophilic archaeal protein, binds RNA in vivo. Mol Microbiol (2003) 1.20
Mutations enabling displacement of tryptophan by 4-fluorotryptophan as a canonical amino acid of the genetic code. Genome Biol Evol (2014) 1.16
Metabolic profiles of Lolium perenne are differentially affected by nitrogen supply, carbohydrate content, and fungal endophyte infection. Plant Physiol (2008) 1.14
p21 is decreased in polycystic kidney disease and leads to increased epithelial cell cycle progression: roscovitine augments p21 levels. BMC Nephrol (2007) 1.11
Estrogen is renoprotective via a nonreceptor-dependent mechanism after cardiac arrest in vivo. Anesthesiology (2010) 1.08
Anxiolytic effect of wogonin, a benzodiazepine receptor ligand isolated from Scutellaria baicalensis Georgi. Biochem Pharmacol (2002) 1.08
Zwitterionic carboxybetaine polymer surfaces and their resistance to long-term biofilm formation. Biomaterials (2009) 1.08
Estrogen protects renal endothelial barrier function from ischemia-reperfusion in vitro and in vivo. Am J Physiol Renal Physiol (2012) 1.07
Expression of the R2R3-MYB transcription factor TaMYB14 from Trifolium arvense activates proanthocyanidin biosynthesis in the legumes Trifolium repens and Medicago sativa. Plant Physiol (2012) 1.05
Identifying main effects and epistatic interactions from large-scale SNP data via adaptive group Lasso. BMC Bioinformatics (2010) 1.05
Ultra low fouling zwitterionic polymers with a biomimetic adhesive group. Biomaterials (2008) 1.04
A neurochemical approach to valuation sensitivity over gains and losses. Proc Biol Sci (2009) 1.03
Rho kinase inhibition protects kidneys from diabetic nephropathy without reducing blood pressure. Kidney Int (2010) 1.02
The heritability of attitude toward economic risk. Twin Res Hum Genet (2009) 1.02
Functionalizable and ultra-low fouling zwitterionic surfaces via adhesive mussel mimetic linkages. Biomaterials (2009) 1.01
Renal p38 MAP kinase activity in experimental diabetes. Lab Invest (2007) 1.01
A switchable biocompatible polymer surface with self-sterilizing and nonfouling capabilities. Angew Chem Int Ed Engl (2008) 1.00
MegaSNPHunter: a learning approach to detect disease predisposition SNPs and high level interactions in genome wide association study. BMC Bioinformatics (2009) 1.00
Therapeutic potential of wogonin: a naturally occurring flavonoid. CNS Drug Rev (2005) 0.98
Functional effects of nonsynonymous polymorphisms in the human TRPV1 gene. Am J Physiol Renal Physiol (2007) 0.97
Pursuing "zero" protein adsorption of poly(carboxybetaine) from undiluted blood serum and plasma. Langmuir (2009) 0.97
"I want to meet other kids like me": support needs of children with asthma and allergies. Issues Compr Pediatr Nurs (2011) 0.97
Monoamine oxidase A gene (MAOA) associated with attitude towards longshot risks. PLoS One (2009) 0.97
Epidemics of overweight and obesity among growing childhood in China between 1997 and 2009: Impact of Family Income, Dietary Intake, and Physical Activity Dynamics. Chin Med J (Engl) (2015) 0.97
Recognition by tryptophanyl-tRNA synthetases of discriminator base on tRNATrp from three biological domains. J Biol Chem (2002) 0.97
Alu-associated enhancement of single nucleotide polymorphisms in the human genome. Gene (2005) 0.96
Dopamine D4 receptor gene associated with fairness preference in ultimatum game. PLoS One (2010) 0.95
Positive selection within the Schizophrenia-associated GABA(A) receptor beta(2) gene. PLoS One (2007) 0.95
Changes in brain G proteins and colonic sympathetic neural signaling in chronic-acute combined stress rat model of irritable bowel syndrome (IBS). Transl Res (2008) 0.94
Multi-task learning for cross-platform siRNA efficacy prediction: an in-silico study. BMC Bioinformatics (2010) 0.94
Effects of hormonal contraception on antiretroviral drug metabolism, pharmacokinetics and pharmacodynamics. Am J Reprod Immunol (2014) 0.93
Two conformations of archaeal Ssh10b. The origin of its temperature-dependent interaction with DNA. J Biol Chem (2003) 0.93
GABRB2 association with schizophrenia: commonalities and differences between ethnic groups and clinical subtypes. Biol Psychiatry (2006) 0.93
Ultralow fouling zwitterionic polymers grafted from surfaces covered with an initiator via an adhesive mussel mimetic linkage. J Phys Chem B (2008) 0.92
Crystal structure of a DNA binding protein from the hyperthermophilic euryarchaeon Methanococcus jannaschii. Protein Sci (2003) 0.92
Novel dimeric acetylcholinesterase inhibitor bis7-tacrine, but not donepezil, prevents glutamate-induced neuronal apoptosis by blocking N-methyl-D-aspartate receptors. J Biol Chem (2005) 0.92
Cyclo-oxygenase-2 inhibition attenuates the progression of nephropathy in uninephrectomized diabetic rats. Clin Exp Pharmacol Physiol (2007) 0.92
GABRB2 in schizophrenia and bipolar disorder: disease association, gene expression and clinical correlations. Biochem Soc Trans (2009) 0.92
Association between obesity and metabolic co-morbidities among children and adolescents in South Korea based on national data. BMC Public Health (2014) 0.91
Community navigation for stroke survivors and their care partners: description and evaluation. Top Stroke Rehabil (2010) 0.91
Disorders of Sexual Differentiation: Ethical Considerations Surrounding Early Cosmetic Genital Surgery. Pediatr Nurs (2015) 0.91
Angiotensin AT1 receptor activation mediates high glucose-induced epithelial-mesenchymal transition in renal proximal tubular cells. Clin Exp Pharmacol Physiol (2010) 0.90
A recombination hotspot in a schizophrenia-associated region of GABRB2. PLoS One (2010) 0.90
The use of genomics and metabolomics methods to quantify fungal endosymbionts and alkaloids in grasses. Methods Mol Biol (2012) 0.90
Detecting two-locus associations allowing for interactions in genome-wide association studies. Bioinformatics (2010) 0.89
Anxiolytic-Like Effect of baicalin and its additivity with other anxiolytics. Planta Med (2006) 0.89
GABA(A) receptor subtype selectivity underlying anxiolytic effect of 6-hydroxyflavone. Biochem Pharmacol (2010) 0.89
Gender hormones and the progression of experimental polycystic kidney disease. Kidney Int (2005) 0.89
5,7-Dihydroxy-6-methoxyflavone, a benzodiazepine site ligand isolated from Scutellaria baicalensis Georgi, with selective antagonistic properties. Biochem Pharmacol (2003) 0.89
Imaging and cell targeting characteristics of magnetic nanoparticles modified by a functionalizable zwitterionic polymer with adhesive 3,4-dihydroxyphenyl-l-alanine linkages. Biomaterials (2010) 0.89
Metabolite analysis of the effects of elevated CO2 and nitrogen fertilization on the association between tall fescue (Schedonorus arundinaceus) and its fungal symbiont Neotyphodium coenophialum. Plant Cell Environ (2013) 0.89
Uniform zwitterionic polymer hydrogels with a nonfouling and functionalizable crosslinker using photopolymerization. Biomaterials (2011) 0.88
Enhanced phosphorylation of Na(+)-Cl- co-transporter in experimental metabolic syndrome: role of insulin. Clin Sci (Lond) (2012) 0.88
Cysteine mutants of human apolipoprotein A-I: a study of secondary structural and functional properties. J Lipid Res (2005) 0.88
Ultra-low fouling and functionalizable zwitterionic coatings grafted onto SiO2 via a biomimetic adhesive group for sensing and detection in complex media. Biosens Bioelectron (2010) 0.87
Applicability of a sensitive duplex real-time PCR assay for identifying B/Yamagata and B/Victoria lineages of influenza virus from clinical specimens. Appl Microbiol Biotechnol (2011) 0.87
A novel recombinant peptide containing only two T-cell tolerance epitopes of chicken type II collagen that suppresses collagen-induced arthritis. Mol Immunol (2008) 0.87
Nanoparticles for drug delivery prepared from amphiphilic PLGA zwitterionic block copolymers with sharp contrast in polarity between two blocks. Angew Chem Int Ed Engl (2010) 0.87
AluScan: a method for genome-wide scanning of sequence and structure variations in the human genome. BMC Genomics (2011) 0.87
An antibody to IP-10 is a potent antagonist of cell migration in vitro and in vivo and does not affect disease in several animal models of inflammation. Autoimmunity (2009) 0.86
Semi-supervised protein subcellular localization. BMC Bioinformatics (2009) 0.86
Effects of long-term inhibition of neuronal nitric oxide synthase (NOS1) in uninephrectomized diabetic rats. Nitric Oxide (2004) 0.86
Documentation and management of CKD in rural primary care. Clin J Am Soc Nephrol (2013) 0.86
Polyphasic evidence delineating the root of life and roots of biological domains. Gene (2007) 0.86
Endothelial-derived vasoactive mediators in polycystic kidney disease. Kidney Int (2003) 0.86
Examining social norm impacts on obesity and eating behaviors among US school children based on agent-based model. BMC Public Health (2014) 0.86
Predicting the risk of hyperkalemia in patients with chronic kidney disease starting lisinopril. Pharmacoepidemiol Drug Saf (2010) 0.85