Published in Nat Med on November 18, 2007
Extrathymic generation of regulatory T cells in placental mammals mitigates maternal-fetal conflict. Cell (2012) 3.24
Turning 'sweet' on immunity: galectin-glycan interactions in immune tolerance and inflammation. Nat Rev Immunol (2009) 3.22
Mammalian glycosylation in immunity. Nat Rev Immunol (2008) 2.74
The immune system in pregnancy: a unique complexity. Am J Reprod Immunol (2010) 2.33
Tolerogenic signals delivered by dendritic cells to T cells through a galectin-1-driven immunoregulatory circuit involving interleukin 27 and interleukin 10. Nat Immunol (2009) 2.23
Dendritic cell control of tolerogenic responses. Immunol Rev (2011) 2.13
Inflammation and pregnancy: the role of the immune system at the implantation site. Ann N Y Acad Sci (2011) 1.76
Fetomaternal immune cross-talk and its consequences for maternal and offspring's health. Nat Med (2013) 1.54
Regulatory T-cells and immune tolerance in pregnancy: a new target for infertility treatment? Hum Reprod Update (2009) 1.43
HLA-G homodimer-induced cytokine secretion through HLA-G receptors on human decidual macrophages and natural killer cells. Proc Natl Acad Sci U S A (2009) 1.41
Mechanisms of T cell tolerance towards the allogeneic fetus. Nat Rev Immunol (2012) 1.39
When galectins recognize glycans: from biochemistry to physiology and back again. Biochemistry (2011) 1.34
Physiological and molecular determinants of embryo implantation. Mol Aspects Med (2013) 1.33
Overview of the immune response. J Allergy Clin Immunol (2010) 1.32
Dimeric Galectin-8 induces phosphatidylserine exposure in leukocytes through polylactosamine recognition by the C-terminal domain. J Biol Chem (2008) 1.27
Interleukin-10: a multi-faceted agent of pregnancy. Am J Reprod Immunol (2010) 1.17
Galectin-7 in the control of epidermal homeostasis after injury. Mol Biol Cell (2008) 1.11
Natural killer cells promote immune tolerance by regulating inflammatory TH17 cells at the human maternal-fetal interface. Proc Natl Acad Sci U S A (2012) 1.11
Stress and reproductive failure: past notions, present insights and future directions. J Assist Reprod Genet (2008) 1.10
Suppression of autoimmune diabetes by soluble galectin-1. J Immunol (2009) 1.06
Adhesion molecules in endometrial epithelium: tissue integrity and embryo implantation. J Anat (2009) 1.05
Development of a nascent galectin-1 chimeric molecule for studying the role of leukocyte galectin-1 ligands and immune disease modulation. J Immunol (2010) 1.04
TIM-3 regulates innate immune cells to induce fetomaternal tolerance. J Immunol (2012) 1.04
A primate subfamily of galectins expressed at the maternal-fetal interface that promote immune cell death. Proc Natl Acad Sci U S A (2009) 1.04
NK cells in immunotolerant organs. Cell Mol Immunol (2013) 1.01
Galectin-1 reduces the severity of herpes simplex virus-induced ocular immunopathological lesions. J Immunol (2012) 1.00
T cell apoptosis at the maternal-fetal interface in early human pregnancy, involvement of galectin-1. Proc Natl Acad Sci U S A (2008) 0.99
The hidden maternal-fetal interface: events involving the lymphoid organs in maternal-fetal tolerance. Int J Dev Biol (2010) 0.97
Manifestations of immune tolerance in the human female reproductive tract. Front Immunol (2013) 0.94
Blockage of heme oxygenase-1 abrogates the protective effect of regulatory T cells on murine pregnancy and promotes the maturation of dendritic cells. PLoS One (2012) 0.92
Split immunological tolerance to trophoblast. Int J Dev Biol (2010) 0.92
Emergence of hormonal and redox regulation of galectin-1 in placental mammals: implication in maternal-fetal immune tolerance. Proc Natl Acad Sci U S A (2008) 0.92
Galectins: guardians of eutherian pregnancy at the maternal-fetal interface. Trends Endocrinol Metab (2011) 0.92
Expanding the universe of cytokines and pattern recognition receptors: galectins and glycans in innate immunity. J Clin Immunol (2010) 0.92
Galectin-1 co-clusters CD43/CD45 on dendritic cells and induces cell activation and migration through Syk and protein kinase C signaling. J Biol Chem (2009) 0.91
Immunologic regulation in pregnancy: from mechanism to therapeutic strategy for immunomodulation. Clin Dev Immunol (2011) 0.91
Severe preeclampsia is characterized by increased placental expression of galectin-1. J Matern Fetal Neonatal Med (2008) 0.91
Dendritic cells: a family portrait at mid-gestation. Immunology (2008) 0.91
Glycosylation at the fetomaternal interface: does the glycocode play a critical role in implantation? Glycoconj J (2008) 0.89
Stress-induced neurogenic inflammation in murine skin skews dendritic cells towards maturation and migration: key role of intercellular adhesion molecule-1/leukocyte function-associated antigen interactions. Am J Pathol (2008) 0.88
Placental Protein 13 (PP13) - A Placental Immunoregulatory Galectin Protecting Pregnancy. Front Immunol (2014) 0.87
Uterine NK cells are critical in shaping DC immunogenic functions compatible with pregnancy progression. PLoS One (2012) 0.86
Progesterone and HMOX-1 promote fetal growth by CD8+ T cell modulation. J Clin Invest (2015) 0.86
Maternal floor infarction/massive perivillous fibrin deposition: a manifestation of maternal antifetal rejection? Am J Reprod Immunol (2013) 0.86
Galectin-1 is part of human trophoblast invasion machinery--a functional study in vitro. PLoS One (2011) 0.86
Is Infant Immunity Actively Suppressed or Immature? Virology (Auckl) (2014) 0.86
Maternal HLA panel-reactive antibodies in early gestation positively correlate with chronic chorioamnionitis: evidence in support of the chronic nature of maternal anti-fetal rejection. Am J Reprod Immunol (2011) 0.86
Immunotherapy using lipopolysaccharide-stimulated bone marrow-derived dendritic cells to treat experimental autoimmune encephalomyelitis. Clin Exp Immunol (2014) 0.86
Galectin-1-mediated suppression of Pseudomonas aeruginosa-induced corneal immunopathology. J Immunol (2013) 0.85
Immune surveillance of the maternal/fetal interface: controversies and implications. Trends Endocrinol Metab (2010) 0.85
Chorioamnionitis and increased galectin-1 expression in PPROM --an anti-inflammatory response in the fetal membranes? Am J Reprod Immunol (2008) 0.85
The anti-angiogenic peptide anginex greatly enhances galectin-1 binding affinity for glycoproteins. J Biol Chem (2011) 0.84
IL-10 deficiency blocks the ability of LPS to regulate expression of tolerance-related molecules on dendritic cells. Eur J Immunol (2012) 0.84
VIP modulates the pro-inflammatory maternal response, inducing tolerance to trophoblast cells. Br J Pharmacol (2009) 0.84
B7h (ICOS-L) maintains tolerance at the fetomaternal interface. Am J Pathol (2013) 0.84
Intravenous transfer of apoptotic cell-treated dendritic cells leads to immune tolerance by blocking Th17 cell activity. Immunobiology (2013) 0.84
Methylome of fetal and maternal monocytes and macrophages at the feto-maternal interface. Am J Reprod Immunol (2012) 0.84
T cell behavior at the maternal-fetal interface. Int J Dev Biol (2014) 0.83
Dynamics of regulatory T-cells during pregnancy: effect of HIV infection and correlations with other immune parameters. PLoS One (2011) 0.83
PP13, maternal ABO blood groups and the risk assessment of pregnancy complications. PLoS One (2011) 0.83
Characterization of the fetal blood transcriptome and proteome in maternal anti-fetal rejection: evidence of a distinct and novel type of human fetal systemic inflammatory response. Am J Reprod Immunol (2013) 0.83
The decidua-the maternal bed embracing the embryo-maintains the pregnancy. Semin Immunopathol (2016) 0.83
The leukocyte activation receptor CD69 controls T cell differentiation through its interaction with galectin-1. Mol Cell Biol (2014) 0.83
Differential expression of immunomodulatory galectin-1 in peripheral leukocytes and adult tissues and its cytosolic organization in striated muscle. Glycobiology (2010) 0.83
Perinatal Listeria monocytogenes susceptibility despite preconceptual priming and maintenance of pathogen-specific CD8(+) T cells during pregnancy. Cell Mol Immunol (2014) 0.82
Detection of anti-HLA antibodies in maternal blood in the second trimester to identify patients at risk of antibody-mediated maternal anti-fetal rejection and spontaneous preterm delivery. Am J Reprod Immunol (2013) 0.82
Myeloid derived suppressor cells are present at high frequency in neonates and suppress in vitro T cell responses. PLoS One (2014) 0.81
Interfering with Gal-1-mediated angiogenesis contributes to the pathogenesis of preeclampsia. Proc Natl Acad Sci U S A (2013) 0.81
Maternal CD4⁺ and CD8⁺ T cell tolerance towards a fetal minor histocompatibility antigen in T cell receptor transgenic mice. Biol Reprod (2013) 0.81
Seminal CD38 is a pivotal regulator for fetomaternal tolerance. Proc Natl Acad Sci U S A (2015) 0.81
Regulatory T cells and the immune pathogenesis of prenatal infection. Reproduction (2013) 0.81
In vivo experiments reveal the good, the bad and the ugly faces of sFlt-1 in pregnancy. PLoS One (2014) 0.80
Extracellular Vesicles in Physiology, Pathology, and Therapy of the Immune and Central Nervous System, with Focus on Extracellular Vesicles Derived from Mesenchymal Stem Cells as Therapeutic Tools. Front Cell Neurosci (2016) 0.80
Duodenal intraepithelial lymphocytes of children with cow milk allergy preferentially bind the glycan-binding protein galectin-3. Int J Immunopathol Pharmacol (2009) 0.79
Immunology of hepatic diseases during pregnancy. Semin Immunopathol (2016) 0.78
Melanoma Cell Galectin-1 Ligands Functionally Correlate with Malignant Potential. J Invest Dermatol (2015) 0.78
The role of pregnancy-associated hormones in the development and function of regulatory B cells. Front Endocrinol (Lausanne) (2014) 0.78
Galectin-8 Ameliorates Murine Autoimmune Ocular Pathology and Promotes a Regulatory T Cell Response. PLoS One (2015) 0.78
Transmembrane protein 147 (TMEM147): another partner protein of Haemonchus contortus galectin on the goat peripheral blood mononuclear cells (PBMC). Parasit Vectors (2016) 0.77
Diet-induced obesity may affect the uterine immune environment in early-mid pregnancy, reducing NK-cell activity and potentially compromising uterine vascularization. Int J Obes (Lond) (2013) 0.77
"Time sweet time": circadian characterization of galectin-1 null mice. J Circadian Rhythms (2010) 0.77
The Uterine Immune Profile May Help Women With Repeated Unexplained Embryo Implantation Failure After In Vitro Fertilization. Am J Reprod Immunol (2016) 0.76
Galectin-1 reduction and changes in T regulatory cells may play crucial roles in patients with unexplained recurrent spontaneous abortion. Int J Clin Exp Pathol (2015) 0.76
Dual roles of endogenous and exogenous galectin-1 in the control of testicular immunopathology. Sci Rep (2015) 0.76
Defects in the vasoactive intestinal peptide (VIP)/VPAC system during early stages of the placental-maternal leucocyte interaction impair the maternal tolerogenic response. Clin Exp Immunol (2012) 0.76
Increased maternal T cell microchimerism in the allogeneic fetus during LPS-induced preterm labor in mice. Chimerism (2015) 0.76
Galectin-1 links tumor hypoxia and radiotherapy. Glycobiology (2014) 0.76
Galectins: Double-edged Swords in the Cross-roads of Pregnancy Complications and Female Reproductive Tract Inflammation and Neoplasia. J Pathol Transl Med (2015) 0.76
Engineering galectin-glycan interactions for immunotherapy and immunomodulation. Exp Biol Med (Maywood) (2016) 0.75
Glucocorticoid receptor in T cells mediates protection from autoimmunity in pregnancy. Proc Natl Acad Sci U S A (2017) 0.75
The sterile and tolerogenic fetal niche does not restrict the generation of CD4 T memory cells. Ann Transl Med (2015) 0.75
Placental Expression Patterns of Galectin-1, Galectin-2, Galectin-3 and Galectin-13 in Cases of Intrauterine Growth Restriction (IUGR). Int J Mol Sci (2016) 0.75
Galectin-1 markedly reduces the incidence of resorptions in mice missing immunophilin FKBP52. Endocrinology (2012) 0.75
Intestinal tumorigenesis is not affected by progesterone signaling in rodent models. PLoS One (2011) 0.75
Interaction of extravillous trophoblast galectin-1 and mucin(s)-Is there a functional relevance? Cell Adh Migr (2015) 0.75
Differential mouse-strain specific expression of Junctional Adhesion Molecule (JAM)-B in placental structures. Cell Adh Migr (2016) 0.75
Decoding the chemokine network that links leukocytes with decidual cells and the trophoblast during early implantation. Cell Adh Migr (2016) 0.75
Prototype and Chimera-Type Galectins in Placentas with Spontaneous and Recurrent Miscarriages. Int J Mol Sci (2016) 0.75
Galectin-1 overexpression in endometriosis and its regulation by neuropeptides (CRH, UCN) indicating its important role in reproduction and inflammation. PLoS One (2014) 0.75
The role of Galectin-1 and Galectin-3 in the mucosal immune response to Citrobacter rodentium infection. PLoS One (2014) 0.75
Galectins as modulators of tumour progression. Nat Rev Cancer (2005) 5.30
Differential activation of the dorsal striatum by high-calorie visual food stimuli in obese individuals. Neuroimage (2007) 3.25
Turning 'sweet' on immunity: galectin-glycan interactions in immune tolerance and inflammation. Nat Rev Immunol (2009) 3.22
Differential glycosylation of TH1, TH2 and TH-17 effector cells selectively regulates susceptibility to cell death. Nat Immunol (2007) 3.07
Protein-glycan interactions in the control of innate and adaptive immune responses. Nat Immunol (2008) 2.77
Galectin-3 regulates myofibroblast activation and hepatic fibrosis. Proc Natl Acad Sci U S A (2006) 2.75
Galectins: structure, function and therapeutic potential. Expert Rev Mol Med (2008) 2.61
Development of a computer-adaptive test for depression (D-CAT). Qual Life Res (2005) 2.50
Targeted inhibition of galectin-1 gene expression in tumor cells results in heightened T cell-mediated rejection; A potential mechanism of tumor-immune privilege. Cancer Cell (2004) 2.46
A comparative study of the anti-inflammatory, anticoagulant, antiangiogenic, and antiadhesive activities of nine different fucoidans from brown seaweeds. Glycobiology (2007) 2.45
The AP1-dependent secretion of galectin-1 by Reed Sternberg cells fosters immune privilege in classical Hodgkin lymphoma. Proc Natl Acad Sci U S A (2007) 2.31
Introduction to galectins. Glycoconj J (2004) 2.30
Tolerogenic signals delivered by dendritic cells to T cells through a galectin-1-driven immunoregulatory circuit involving interleukin 27 and interleukin 10. Nat Immunol (2009) 2.23
Galectin-1 deactivates classically activated microglia and protects from inflammation-induced neurodegeneration. Immunity (2012) 2.18
The impact of dydrogesterone supplementation on hormonal profile and progesterone-induced blocking factor concentrations in women with threatened abortion. Am J Reprod Immunol (2005) 2.01
Functions of cell surface galectin-glycoprotein lattices. Curr Opin Struct Biol (2007) 1.97
Circulating levels of irisin in patients with anorexia nervosa and different stages of obesity--correlation with body mass index. Peptides (2012) 1.95
Galectins: regulators of acute and chronic inflammation. Ann N Y Acad Sci (2010) 1.83
Galectin-3, a marker for vacuole lysis by invasive pathogens. Cell Microbiol (2009) 1.79
A unique galectin signature in human prostate cancer progression suggests galectin-1 as a key target for treatment of advanced disease. Cancer Res (2012) 1.74
Further exploring the brain-skin connection: stress worsens dermatitis via substance P-dependent neurogenic inflammation in mice. J Invest Dermatol (2007) 1.67
Central nesfatin-1 reduces dark-phase food intake and gastric emptying in rats: differential role of corticotropin-releasing factor2 receptor. Endocrinology (2009) 1.66
[Standardized diagnosing: computer-assisted (CIDI) diagnoses compared to clinically-judged diagnoses in a psychosomatic setting]. Psychother Psychosom Med Psychol (2006) 1.59
Neuronal plasticity of the "brain-skin connection": stress-triggered up-regulation of neuropeptides in dorsal root ganglia and skin via nerve growth factor-dependent pathways. J Mol Med (Berl) (2007) 1.58
Somatic comorbidities of irritable bowel syndrome: a systematic analysis. J Psychosom Res (2008) 1.54
Viral induction and targeted inhibition of galectin-1 in EBV+ posttransplant lymphoproliferative disorders. Blood (2011) 1.53
The role of invariant NKT cells in pre-eclampsia. Am J Reprod Immunol (2008) 1.49
Bombesin, but not amylin, blocks the orexigenic effect of peripheral ghrelin. Am J Physiol Regul Integr Comp Physiol (2006) 1.47
A novel function for galectin-1 at the crossroad of innate and adaptive immunity: galectin-1 regulates monocyte/macrophage physiology through a nonapoptotic ERK-dependent pathway. J Immunol (2007) 1.46
The network of psychological variables in patients with diabetes and their importance for quality of life and metabolic control. Diabetes Care (2002) 1.46
The Perceived Stress Questionnaire (PSQ) reconsidered: validation and reference values from different clinical and healthy adult samples. Psychosom Med (2005) 1.46
Development and evaluation of a computer adaptive test for 'Anxiety' (Anxiety-CAT). Qual Life Res (2007) 1.45
Targeting galectin-1 overcomes breast cancer-associated immunosuppression and prevents metastatic disease. Cancer Res (2012) 1.44
Dydrogesterone supplementation in women with threatened preterm delivery--the impact on cytokine profile, hormone profile, and progesterone-induced blocking factor. J Reprod Immunol (2011) 1.43
Galectin-1 suppresses experimental colitis in mice. Gastroenterology (2003) 1.41
Maternal serum progesterone-induced blocking factor at 11-13 weeks' gestation in spontaneous early preterm delivery. Fetal Diagn Ther (2011) 1.39
Galectin-1 suppresses autoimmune retinal disease by promoting concomitant Th2- and T regulatory-mediated anti-inflammatory responses. J Immunol (2006) 1.37
When galectins recognize glycans: from biochemistry to physiology and back again. Biochemistry (2011) 1.34
Disrupting galectin-1 interactions with N-glycans suppresses hypoxia-driven angiogenesis and tumorigenesis in Kaposi's sarcoma. J Exp Med (2012) 1.31
Role of galectins in inflammatory and immunomodulatory processes. Biochim Biophys Acta (2002) 1.25
Early risk factors for miscarriage: a prospective cohort study in pregnant women. Reprod Biomed Online (2008) 1.25
Burden of hair loss: stress and the underestimated psychosocial impact of telogen effluvium and androgenetic alopecia. J Invest Dermatol (2004) 1.24
Galectin-3 mediates IL-4-induced survival and differentiation of B cells: functional cross-talk and implications during Trypanosoma cruzi infection. J Immunol (2004) 1.24
Prenatal stress enhances susceptibility of murine adult offspring toward airway inflammation. J Immunol (2006) 1.24
Conveying glycan information into T-cell homeostatic programs: a challenging role for galectin-1 in inflammatory and tumor microenvironments. Immunol Rev (2009) 1.24
Risk factors and correlates of deliberate self-harm behavior: a systematic review. J Psychosom Res (2009) 1.22
Stress inhibits hair growth in mice by induction of premature catagen development and deleterious perifollicular inflammatory events via neuropeptide substance P-dependent pathways. Am J Pathol (2003) 1.22
Dendritic cells: key to fetal tolerance? Biol Reprod (2007) 1.21
Dynamic cross-talk between tumor and immune cells in orchestrating the immunosuppressive network at the tumor microenvironment. Cancer Immunol Immunother (2007) 1.21
Towards a "free radical theory of graying": melanocyte apoptosis in the aging human hair follicle is an indicator of oxidative stress induced tissue damage. FASEB J (2006) 1.21
Lineage, maturity, and phenotype of uterine murine dendritic cells throughout gestation indicate a protective role in maintaining pregnancy. Biol Reprod (2003) 1.20
NF-kappa B regulates expression of the MHC class I-related chain A gene in activated T lymphocytes. J Immunol (2004) 1.20
Tolerance signaling molecules and pregnancy: IDO, galectins, and the renaissance of regulatory T cells. Am J Reprod Immunol (2007) 1.20
Galectin-3 and soluble fibrinogen act in concert to modulate neutrophil activation and survival: involvement of alternative MAPK pathways. Glycobiology (2004) 1.18
Intracellular retention of the NKG2D ligand MHC class I chain-related gene A in human melanomas confers immune privilege and prevents NK cell-mediated cytotoxicity. J Immunol (2008) 1.17
Galectin-1 sensitizes resting human T lymphocytes to Fas (CD95)-mediated cell death via mitochondrial hyperpolarization, budding, and fission. J Biol Chem (2004) 1.17
Progesterone during pregnancy: endocrine-immune cross talk in mammalian species and the role of stress. Am J Reprod Immunol (2007) 1.15
Desacyl ghrelin inhibits the orexigenic effect of peripherally injected ghrelin in rats. Peptides (2008) 1.14
Leukemia inhibitory factor triggers activation of signal transducer and activator of transcription 3, proliferation, invasiveness, and altered protease expression in choriocarcinoma cells. Int J Biochem Cell Biol (2005) 1.14
Physicians' working conditions and job satisfaction: does hospital ownership in Germany make a difference? BMC Health Serv Res (2009) 1.14
General and visceral surgery practice in German hospitals: a real-time work analysis on surgeons' work flow. Langenbecks Arch Surg (2009) 1.13
Hair growth inhibition by psychoemotional stress: a mouse model for neural mechanisms in hair growth control. Exp Dermatol (2006) 1.13
AP1-dependent galectin-1 expression delineates classical hodgkin and anaplastic large cell lymphomas from other lymphoid malignancies with shared molecular features. Clin Cancer Res (2008) 1.11
Introducing a mouse model for pre-eclampsia: adoptive transfer of activated Th1 cells leads to pre-eclampsia-like symptoms exclusively in pregnant mice. Eur J Immunol (2004) 1.09
Three assessment tools for deliberate self-harm and suicide behavior: evaluation and psychopathological correlates. J Psychosom Res (2006) 1.08
Trophoblast invasion: the role of intracellular cytokine signalling via signal transducer and activator of transcription 3 (STAT3). Hum Reprod Update (2008) 1.08
Cognitive-enhancing substance use at German universities: frequency, reasons and gender differences. Wien Med Wochenschr (2012) 1.07