PubRank

Roger F Butterworth

Author PubWeight™ 70.41‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Neurobiology of ammonia. Prog Neurobiol 2002 1.84
2 Effects of hypothermia on brain glucose metabolism in acute liver failure: a H/C-nuclear magnetic resonance study. Gastroenterology 2003 1.60
3 Alterations in expression of genes coding for proteins of the neurovascular unit in ischemic liver failure. Neurochem Int 2009 1.55
4 Effect of albumin dialysis on intracranial pressure increase in pigs with acute liver failure: a randomized study. Crit Care Med 2006 1.50
5 Perispinal etanercept for post-stroke neurological and cognitive dysfunction: scientific rationale and current evidence. CNS Drugs 2014 1.49
6 Increased brain serotonin turnover correlates with the degree of shunting and hyperammonemia in rats following variable portal vein stenosis. J Hepatol 2004 1.44
7 Update of cell damage mechanisms in thiamine deficiency: focus on oxidative stress, excitotoxicity and inflammation. Alcohol Alcohol 2009 1.11
8 Cerebral inflammation contributes to encephalopathy and brain edema in acute liver failure: protective effect of minocycline. J Neurochem 2009 1.08
9 Neurobiological characterization of an azoxymethane mouse model of acute liver failure. Neurochem Int 2006 1.07
10 Ammonia induces MK-801-sensitive nitration and phosphorylation of protein tyrosine residues in rat astrocytes. FASEB J 2002 1.07
11 Direct evidence for central proinflammatory mechanisms in rats with experimental acute liver failure: protective effect of hypothermia. J Cereb Blood Flow Metab 2009 1.06
12 Mild hypothermia attenuates liver injury and improves survival in mice with acetaminophen toxicity. Gastroenterology 2006 1.04
13 IL-1 or TNF receptor gene deletion delays onset of encephalopathy and attenuates brain edema in experimental acute liver failure. Neurochem Int 2009 1.01
14 N-acetylcysteine attenuates cerebral complications of non-acetaminophen-induced acute liver failure in mice: antioxidant and anti-inflammatory mechanisms. Metab Brain Dis 2010 1.00
15 Direct molecular and spectroscopic evidence for increased ammonia removal capacity of skeletal muscle in acute liver failure. J Hepatol 2006 0.97
16 Selective increase of brain lactate synthesis in experimental acute liver failure: results of a [H-C] nuclear magnetic resonance study. Hepatology 2003 0.93
17 Pathogenesis of hepatic encephalopathy: new insights from neuroimaging and molecular studies. J Hepatol 2003 0.93
18 Role of mitochondrial dysfunction and oxidative stress in the pathogenesis of selective neuronal loss in Wernicke's encephalopathy. Mol Neurobiol 2005 0.92
19 Mitochondrial dysfunction in acute hyperammonemia. Neurochem Int 2002 0.92
20 Pathogenesis of hepatic encephalopathy and brain edema in acute liver failure: role of glutamine redefined. Neurochem Int 2012 0.91
21 Inflammatory cascades driven by tumor necrosis factor-alpha play a major role in the progression of acute liver failure and its neurological complications. PLoS One 2012 0.91
22 The neurosteroid system: implication in the pathophysiology of hepatic encephalopathy. Neurochem Int 2007 0.91
23 Acute liver failure: a critical appraisal of available animal models. Metab Brain Dis 2005 0.90
24 Increased brain endothelial nitric oxide synthase expression in thiamine deficiency: relationship to selective vulnerability. Neurochem Int 2004 0.87
25 Liver-brain proinflammatory signalling in acute liver failure: role in the pathogenesis of hepatic encephalopathy and brain edema. Metab Brain Dis 2012 0.87
26 Loss of expression of glial fibrillary acidic protein in acute hyperammonemia. Neurochem Int 2002 0.87
27 Mild hypothermia in the prevention of brain edema in acute liver failure: mechanisms and clinical prospects. Metab Brain Dis 2002 0.86
28 Altered expression of tight junction proteins and matrix metalloproteinases in thiamine-deficient mouse brain. Neurochem Int 2009 0.86
29 Ammonia and proinflammatory cytokines modify expression of genes coding for astrocytic proteins implicated in brain edema in acute liver failure. Metab Brain Dis 2010 0.86
30 Keeping cool in acute liver failure: rationale for the use of mild hypothermia. J Hepatol 2005 0.86
31 The brain glutamate system in liver failure. J Neurochem 2006 0.85
32 Dehydroascorbic acid normalizes several markers of oxidative stress and inflammation in acute hyperglycemic focal cerebral ischemia in the rat. Neurochem Int 2005 0.85
33 Region selective alterations of soluble guanylate cyclase content and modulation in brain of cirrhotic patients. Hepatology 2002 0.85
34 Minocycline attenuates oxidative/nitrosative stress and cerebral complications of acute liver failure in rats. Neurochem Int 2009 0.85
35 Manganese distribution in the brain and neurobehavioral changes following inhalation exposure of rats to three chemical forms of manganese. Neurotoxicology 2004 0.84
36 Increased levels of pregnenolone and its neuroactive metabolite allopregnanolone in autopsied brain tissue from cirrhotic patients who died in hepatic coma. Neurochem Int 2006 0.84
37 Normal coupling of brain benzodiazepine and neurosteroid modulatory sites on the GABA-A receptor complex in human hepatic encephalopathy. Neurochem Int 2003 0.84
38 Selective alterations of brain osmolytes in acute liver failure: protective effect of mild hypothermia. Brain Res 2004 0.83
39 Antioxidant and anti-inflammatory effects of mild hypothermia in the attenuation of liver injury due to azoxymethane toxicity in the mouse. Metab Brain Dis 2010 0.83
40 Increased Na, K-ATPase alpha2 isoform gene expression by ammonia in astrocytes and in brain in vivo. Neurochem Int 2010 0.83
41 Lipopolysaccharide precipitates hepatic encephalopathy and increases blood-brain barrier permeability in mice with acute liver failure. Liver Int 2013 0.83
42 Selective increase of neuronal cyclooxygenase-2 (COX-2) expression in vulnerable brain regions of rats with experimental Wernicke's encephalopathy: effect of nimesulide. Metab Brain Dis 2008 0.83
43 Increased brain concentrations of a neuroinhibitory steroid in human hepatic encephalopathy. Ann Neurol 2005 0.83
44 Region-selective alterations of glucose oxidation and amino acid synthesis in the thiamine-deficient rat brain: a re-evaluation using 1H/13C nuclear magnetic resonance spectroscopy. J Neurochem 2008 0.83
45 Pathophysiology of hepatic encephalopathy: a new look at GABA from the molecular standpoint. Metab Brain Dis 2004 0.82
46 Induction of astrocytic cyclooxygenase-2 in epileptic patients with hippocampal sclerosis. Neurochem Int 2003 0.82
47 Increased concentrations of histamine and its metabolite, tele-methylhistamine and down-regulation of histamine H3 receptor sites in autopsied brain tissue from cirrhotic patients who died in hepatic coma. J Hepatol 2003 0.82
48 Selectively increased expression of the astrocytic/endothelial glucose transporter protein GLUT1 in acute liver failure. Glia 2006 0.82
49 Up-regulation of caveolin-1 and blood-brain barrier breakdown are attenuated by N-acetylcysteine in thiamine deficiency. Neurochem Int 2010 0.81
50 Expression of superoxide dismutase in hyperglycemic focal cerebral ischemia in the rat. Neurochem Int 2004 0.81
51 Mechanisms of brain edema in acute liver failure and impact of novel therapeutic interventions. Neurol Res 2007 0.81
52 Reduced brain levels of DHEAS in hepatic coma patients: significance for increased GABAergic tone in hepatic encephalopathy. Neurochem Int 2012 0.81
53 Role of nutrition in the management of hepatic encephalopathy in end-stage liver failure. J Nutr Metab 2010 0.80
54 The "peripheral-type" benzodiazepine (omega 3) receptor in hyperammonemic disorders. Neurochem Int 2002 0.80
55 Assessment of bioaccumulation, neuropathology, and neurobehavior following subchronic (90 days) inhalation in Sprague-Dawley rats exposed to manganese phosphate. Toxicol Appl Pharmacol 2002 0.80
56 An interaction between benzodiazepines and neuroactive steroids at GABA A receptors in cultured hippocampal neurons. Neurochem Int 2006 0.80
57 The biosynthesis of ascorbate protects isolated rat hepatocytes from cumene hydroperoxide-mediated oxidative stress. Free Radic Biol Med 2005 0.80
58 Evidence for oxidative/nitrosative stress in the pathogenesis of hepatic encephalopathy. Metab Brain Dis 2010 0.80
59 Increased brain concentrations of endogenous (non-benzodiazepine) GABA-A receptor ligands in human hepatic encephalopathy. Metab Brain Dis 2004 0.79
60 Expression of astrocytic genes coding for proteins implicated in neural excitation and brain edema is altered after acute liver failure. J Neurochem 2013 0.79
61 Mild hypothermia for the treatment of acute liver failure--what are we waiting for? Nat Clin Pract Gastroenterol Hepatol 2007 0.79
62 Primary cultures of rat astrocytes respond to thiamine deficiency-induced swelling by downregulating aquaporin-4 levels. Neurosci Lett 2004 0.79
63 Mild hypothermia prevents brain edema and attenuates up-regulation of the astrocytic benzodiazepine receptor in experimental acute liver failure. J Hepatol 2005 0.79
64 The neurosteroid system: an emerging therapeutic target for hepatic encephalopathy. Metab Brain Dis 2007 0.79
65 Lack of assessment of body temperature in mice with acetaminophen toxicity. Hepatology 2006 0.78
66 Editorial: rifaximin and minimal hepatic encephalopathy. Am J Gastroenterol 2011 0.78
67 Cell-selective effects of ammonia on glutamate transporter and receptor function in the mammalian brain. Neurochem Int 2003 0.78
68 Role of endogenous benzodiazepine ligands and their GABA-A--associated receptors in hepatic encephalopathy. Metab Brain Dis 2005 0.78
69 Hypothermia attenuates oxidative/nitrosative stress, encephalopathy and brain edema in acute (ischemic) liver failure. Neurochem Int 2009 0.78
70 Selective alterations of brain dopamine D(2) receptor binding in cirrhotic patients: results of a (11)C-N-methylspiperone PET study. Metab Brain Dis 2008 0.78
71 Impaired oxidation of branched-chain amino acids in the medial thalamus of thiamine-deficient rats. Metab Brain Dis 2008 0.78
72 eNOS gene deletion restores blood-brain barrier integrity and attenuates neurodegeneration in the thiamine-deficient mouse brain. J Neurochem 2009 0.77
73 Reduced plasma dehydroepiandrosterone sulfate levels are significantly correlated with fatigue severity in patients with primary biliary cirrhosis. Neurochem Int 2007 0.76
74 Selective loss of expression of glutamate GluR2/R3 receptor subunits in cerebellar tissue from a patient with olivopontocerebellar atrophy. Metab Brain Dis 2002 0.76
75 Reduced expression of astrocytic glycine transporter (Glyt-1) in acute liver failure. Metab Brain Dis 2002 0.76
76 Liver: risk of falls in cirrhosis predicted by psychometric testing. Nat Rev Gastroenterol Hepatol 2012 0.76
77 Effects of ammonia on high affinity glutamate uptake and glutamate transporter EAAT3 expression in cultured rat cerebellar granule cells. Neurochem Int 2003 0.76
78 Brain lactate synthesis in thiamine deficiency: a re-evaluation using 1H-13C nuclear magnetic resonance spectroscopy. J Neurosci Res 2004 0.76
79 Glucose loading precipitates focal lactic acidosis in the vulnerable medial thalamus of thiamine-deficient rats. Metab Brain Dis 2007 0.75
80 Differential effects of ammonia on the benzodiazepine modulatory site on the GABA-A receptor complex of human brain. Neurochem Int 2005 0.75