Published in Blood on December 04, 2007
The role of the anaphylatoxins in health and disease. Mol Immunol (2009) 2.95
Molecular intercommunication between the complement and coagulation systems. J Immunol (2010) 2.12
Signaling through C5a receptor and C3a receptor diminishes function of murine natural regulatory T cells. J Exp Med (2013) 1.48
Complement System Part II: Role in Immunity. Front Immunol (2015) 1.31
The role of complement in the early immune response to transplantation. Nat Rev Immunol (2012) 1.26
Complement inhibition in cancer therapy. Semin Immunol (2013) 1.20
Autocrine effects of tumor-derived complement. Cell Rep (2014) 1.16
A complex role for complement in allergic asthma. Expert Rev Clin Immunol (2010) 1.08
Nucleic acids and endosomal pattern recognition: how to tell friend from foe? Front Cell Infect Microbiol (2013) 1.04
Mice lacking C1q or C3 show accelerated rejection of minor H disparate skin grafts and resistance to induction of tolerance. Eur J Immunol (2010) 0.99
Immune cell-derived C3a and C5a costimulate human T cell alloimmunity. Am J Transplant (2013) 0.98
Functional modulation of human monocytes derived DCs by anaphylatoxins C3a and C5a. Immunobiology (2011) 0.97
Role and mechanism of action of complement in regulating T cell immunity. Mol Immunol (2010) 0.97
Recent progress and new perspectives in studying T cell responses to allografts. Am J Transplant (2010) 0.96
Expression of complement components, receptors and regulators by human dendritic cells. Mol Immunol (2011) 0.96
The role of complement component 3 (C3) in differentiation of myeloid-derived suppressor cells. Blood (2013) 0.92
Targeting regulatory T cells in the treatment of type 1 diabetes mellitus. Curr Mol Med (2012) 0.92
Anti-complement component C5 mAb synergizes with CTLA4Ig to inhibit alloreactive T cells and prolong cardiac allograft survival in mice. Am J Transplant (2011) 0.90
An Anti-C1s Monoclonal, TNT003, Inhibits Complement Activation Induced by Antibodies Against HLA. Am J Transplant (2015) 0.89
C5aR expression in a novel GFP reporter gene knockin mouse: implications for the mechanism of action of C5aR signaling in T cell immunity. J Immunol (2012) 0.89
C5a receptor-dependent cell activation by physiological concentrations of desarginated C5a: insights from a novel label-free cellular assay. J Immunol (2012) 0.89
The complement inhibitor FUT-175 suppresses T cell autoreactivity in experimental autoimmune encephalomyelitis. Am J Pathol (2009) 0.88
Deficiency of C5aR prolongs renal allograft survival. J Am Soc Nephrol (2010) 0.88
Decay accelerating factor is essential for successful corneal engraftment. Am J Transplant (2010) 0.87
Innate immunity and resistance to tolerogenesis in allotransplantation. Front Immunol (2012) 0.85
Modified low density lipoprotein stimulates complement C3 expression and secretion via liver X receptor and Toll-like receptor 4 activation in human macrophages. J Biol Chem (2011) 0.84
The "ins and outs" of complement-driven immune responses. Immunol Rev (2016) 0.84
Interleukin-6 Induced "Acute" Phenotypic Microenvironment Promotes Th1 Anti-Tumor Immunity in Cryo-Thermal Therapy Revealed By Shotgun and Parallel Reaction Monitoring Proteomics. Theranostics (2016) 0.83
Abrogation of immune complex glomerulonephritis by native carboxypeptidase and pharmacological antagonism of the C5a receptor. Cell Mol Immunol (2015) 0.83
Innate and adaptive immunologic functions of complement in the host response to Listeria monocytogenes infection. Immunobiology (2016) 0.82
Reduced graft-versus-host disease in C3-deficient mice is associated with decreased donor Th1/Th17 differentiation. Biol Blood Marrow Transplant (2012) 0.81
Complement Component 3 Is Regulated by TWIST1 and Mediates Epithelial-Mesenchymal Transition. J Immunol (2015) 0.80
The innate immune system and transplantation. Cold Spring Harb Perspect Med (2013) 0.79
Complement anaphylatoxins as immune regulators in cancer. Cancer Med (2014) 0.79
APT070 (mirococept), a membrane-localizing C3 convertase inhibitor, attenuates early human islet allograft damage in vitro and in vivo in a humanized mouse model. Br J Pharmacol (2016) 0.76
Immune complex glomerulonephritis following bone marrow transplantation in C3 deficient mice. PLoS One (2008) 0.75
Intranasal peptide-induced tolerance and linked suppression: consequences of complement deficiency. Immunology (2015) 0.75
Complement mediators: key regulators of airway tissue remodeling in asthma. J Transl Med (2015) 0.75
Let's Tie the Knot: Marriage of Complement and Adaptive Immunity in Pathogen Evasion, for Better or Worse. Front Microbiol (2017) 0.75
The role of the complement system in cancer. J Clin Invest (2017) 0.75
Complement proteins C7 and CFH control the stemness of liver cancer cells via LSF-1. Cancer Lett (2015) 0.75
Properdin and factor H production by human dendritic cells modulates their T-cell stimulatory capacity and is regulated by IFN-γ. Eur J Immunol (2017) 0.75
Complement Recognition Pathways in Renal Transplantation. J Am Soc Nephrol (2017) 0.75
CD8(+) T lymphocyte mobilization to virus-infected tissue requires CD4(+) T-cell help. Nature (2009) 4.03
Local synthesis of complement component C3 regulates acute renal transplant rejection. Nat Med (2002) 3.39
Expression profile of microRNAs in serum: a fingerprint for esophageal squamous cell carcinoma. Clin Chem (2010) 2.34
The murine CCR3 receptor regulates both the role of eosinophils and mast cells in allergen-induced airway inflammation and hyperresponsiveness. Proc Natl Acad Sci U S A (2002) 2.24
Plasmacytoid DCs help lymph node DCs to induce anti-HSV CTLs. J Exp Med (2005) 2.23
Replacement of Oct4 by Tet1 during iPSC induction reveals an important role of DNA methylation and hydroxymethylation in reprogramming. Cell Stem Cell (2013) 2.17
Beta cells are responsible for CXCR3-mediated T-cell infiltration in insulitis. Nat Med (2002) 2.17
The chemokine receptor CCR5 plays a key role in the early memory CD8+ T cell response to respiratory virus infections. Immunity (2008) 2.13
Regulation of pulmonary fibrosis by chemokine receptor CXCR3. J Clin Invest (2004) 2.10
Gliadin induces an increase in intestinal permeability and zonulin release by binding to the chemokine receptor CXCR3. Gastroenterology (2008) 1.98
Influence of donor C3 allotype on late renal-transplantation outcome. N Engl J Med (2006) 1.97
Factor I is required for the development of membranoproliferative glomerulonephritis in factor H-deficient mice. J Clin Invest (2008) 1.94
Fc-dependent depletion of activated T cells occurs through CD40L-specific antibody rather than costimulation blockade. Nat Med (2003) 1.92
Chemokine expression during the development and resolution of a pulmonary leukocyte response to influenza A virus infection in mice. J Leukoc Biol (2004) 1.92
An anti-inflammatory function for the complement anaphylatoxin C5a-binding protein, C5L2. J Biol Chem (2005) 1.89
Bis[1,3-bis-(1-benzyl-1H-benzimidazol-2-yl)-2-oxapropane]nickel(II) dipicrate-dimethyl-formamide-ethanol (1/2/0.25). Acta Crystallogr Sect E Struct Rep Online (2009) 1.89
Toll-like receptor 2 agonists exacerbate accelerated nephrotoxic nephritis. J Am Soc Nephrol (2006) 1.87
Evidence for recruitment of plasmacytoid dendritic cell precursors to inflamed lymph nodes through high endothelial venules. Int Immunol (2004) 1.85
C3a mediates epithelial-to-mesenchymal transition in proteinuric nephropathy. J Am Soc Nephrol (2009) 1.85
Pivotal role of CD4+ T cells in renal fibrosis following ureteric obstruction. Kidney Int (2010) 1.83
CXCR3 signaling reduces the severity of experimental autoimmune encephalomyelitis by controlling the parenchymal distribution of effector and regulatory T cells in the central nervous system. J Immunol (2007) 1.83
Bis[1,3-bis-(1-benzyl-1H-benzimidazol-2-yl)-2-oxapropane]zinc(II) dipicrate dimethyl-formamide disolvate. Acta Crystallogr Sect E Struct Rep Online (2009) 1.76
Early granuloma formation after aerosol Mycobacterium tuberculosis infection is regulated by neutrophils via CXCR3-signaling chemokines. Eur J Immunol (2003) 1.74
The C5a receptor (C5aR) C5L2 is a modulator of C5aR-mediated signal transduction. J Biol Chem (2009) 1.73
A 16-week randomized clinical trial of 2000 international units daily vitamin D3 supplementation in black youth: 25-hydroxyvitamin D, adiposity, and arterial stiffness. J Clin Endocrinol Metab (2010) 1.69
Presynaptic localization of neprilysin contributes to efficient clearance of amyloid-beta peptide in mouse brain. J Neurosci (2004) 1.65
Total synthesis of dimeric pyrrole-imidazole alkaloids: sceptrin, ageliferin, nagelamide e, oxysceptrin, nakamuric acid, and the axinellamine carbon skeleton. J Am Chem Soc (2007) 1.65
CXCR3 mediates region-specific antiviral T cell trafficking within the central nervous system during West Nile virus encephalitis. J Immunol (2008) 1.61
Severe disease, unaltered leukocyte migration, and reduced IFN-gamma production in CXCR3-/- mice with experimental autoimmune encephalomyelitis. J Immunol (2006) 1.59
Targeting of mannan-binding lectin-associated serine protease-2 confers protection from myocardial and gastrointestinal ischemia/reperfusion injury. Proc Natl Acad Sci U S A (2011) 1.58
Acupoint-specific fMRI patterns in human brain. Neurosci Lett (2005) 1.57
Dendritic cell synthesis of C3 is required for full T cell activation and development of a Th1 phenotype. J Immunol (2006) 1.57
The salient characteristics of the central effects of acupuncture needling: limbic-paralimbic-neocortical network modulation. Hum Brain Mapp (2009) 1.55
Diagnostic procedures in autism spectrum disorders: a systematic literature review. Eur Child Adolesc Psychiatry (2013) 1.52
Functional magnetic resonance imaging activation of the brain in children: real acupoint versus sham acupoint. J Child Neurol (2010) 1.51
Effect of acupuncture on the brain in children with spastic cerebral palsy using functional neuroimaging (FMRI). J Child Neurol (2008) 1.51
Role of CXCR3-induced donor T-cell migration in acute GVHD. Exp Hematol (2003) 1.46
Collectin-11 detects stress-induced L-fucose pattern to trigger renal epithelial injury. J Clin Invest (2016) 1.43
Chemokine gene expression during fatal murine cerebral malaria and protection due to CXCR3 deficiency. J Immunol (2008) 1.42
Effects of doctor-patient communication on quality of life among breast cancer patients in southern China. Asian Pac J Cancer Prev (2014) 1.41
Delayed and deficient dermal maturation in mice lacking the CXCR3 ELR-negative CXC chemokine receptor. Am J Pathol (2007) 1.38
Local extravascular pool of C3 is a determinant of postischemic acute renal failure. FASEB J (2006) 1.38
C5a receptor (CD88) blockade protects against MPO-ANCA GN. J Am Soc Nephrol (2013) 1.38
Synaptic activity reduces intraneuronal Abeta, promotes APP transport to synapses, and protects against Abeta-related synaptic alterations. J Neurosci (2009) 1.37
An atomic resolution model for assembly, architecture, and function of the Dr adhesins. Mol Cell (2004) 1.37
Cyclic AMP plays a critical role in C3a-receptor-mediated regulation of dendritic cells in antigen uptake and T-cell stimulation. Blood (2008) 1.33
The retromer component SNX6 interacts with dynactin p150(Glued) and mediates endosome-to-TGN transport. Cell Res (2009) 1.33
Suppression of murine cerebral F2-isoprostanes and F4-neuroprostanes from excitotoxicity and innate immune response in vivo by alpha- or gamma-tocopherol. J Chromatogr B Analyt Technol Biomed Life Sci (2005) 1.28
CXCL10-CXCR3 enhances the development of neutrophil-mediated fulminant lung injury of viral and nonviral origin. Am J Respir Crit Care Med (2012) 1.28
Multi-angle ratiometric approach to measure chemical exchange in amide proton transfer imaging. Magn Reson Med (2011) 1.28
Toll-like receptor 4 ligation on intrinsic renal cells contributes to the induction of antibody-mediated glomerulonephritis via CXCL1 and CXCL2. J Am Soc Nephrol (2007) 1.27
The role of complement in the early immune response to transplantation. Nat Rev Immunol (2012) 1.26
Chemical approaches to stem cell biology and therapeutics. Cell Stem Cell (2013) 1.25
Mechanisms of spatial and temporal development of autoimmune vitiligo in tyrosinase-specific TCR transgenic mice. J Immunol (2010) 1.24
Dendritic cell function in allostimulation is modulated by C5aR signaling. J Immunol (2009) 1.24
Blockade of CXCR3 receptor:ligand interactions reduces leukocyte recruitment to the lung and the severity of experimental idiopathic pneumonia syndrome. J Immunol (2004) 1.24
β-catenin as a potential key target for tumor suppression. Int J Cancer (2011) 1.23
Aqua-[1,3-bis-(benzimidazol-2-yl)-2-oxapropane]-diethano-lmanganese(II) dipicrate ethanol disolvate. Acta Crystallogr Sect E Struct Rep Online (2010) 1.22
Unusual microbial xylanases from insect guts. Appl Environ Microbiol (2004) 1.22
Prolongation of cardiac and islet allograft survival by a blocking hamster anti-mouse CXCR3 monoclonal antibody. Transplantation (2008) 1.22
The role of anaphylatoxins C3a and C5a in regulating innate and adaptive immune responses. Inflamm Allergy Drug Targets (2009) 1.22
Substance P signaling mediates BMP-dependent heterotopic ossification. J Cell Biochem (2011) 1.21
CXCR3-/- mice mount an efficient Th1 response but fail to control Leishmania major infection. Eur J Immunol (2005) 1.20
PG490-88, a derivative of triptolide, causes tumor regression and sensitizes tumors to chemotherapy. Mol Cancer Ther (2003) 1.19
IFN-gamma acts on T cells to induce NK cell mobilization and accumulation in target organs. J Immunol (2006) 1.19
Macrophages from C3-deficient mice have impaired potency to stimulate alloreactive T cells. Blood (2005) 1.19
Coronary sinus septal defect (unroofed coronary sinus): echocardiographic diagnosis and surgical treatment. Int J Cardiol (2012) 1.18
Homeostatic proliferation of lymphocytes results in augmented memory-like function and accelerated allograft rejection. J Immunol (2008) 1.17
Optimizing pulsed-chemical exchange saturation transfer imaging sequences. Magn Reson Med (2011) 1.16
Secondary lymphoid tissue chemokine (CCL21) activates CXCR3 to trigger a Cl- current and chemotaxis in murine microglia. J Immunol (2002) 1.15
Abeta-degrading endopeptidase, neprilysin, in mouse brain: synaptic and axonal localization inversely correlating with Abeta pathology. Neurosci Res (2002) 1.14
Scaling law for noise variance and spatial resolution in differential phase contrast computed tomography. Med Phys (2011) 1.13
The roles of streptozotocin neurotoxicity and neutral endopeptidase in murine experimental diabetic neuropathy. Exp Diabetes Res (2010) 1.13
Short, enantioselective total synthesis of sceptrin and ageliferin by programmed oxaquadricyclane fragmentation. Angew Chem Int Ed Engl (2005) 1.13
3BP2 deficiency impairs the response of B cells, but not T cells, to antigen receptor ligation. Mol Cell Biol (2006) 1.13
Efficient T-cell surveillance of the CNS requires expression of the CXC chemokine receptor 3. J Neurosci (2004) 1.13
CNS-specific therapy for ongoing EAE by silencing IL-17 pathway in astrocytes. Mol Ther (2012) 1.12
TLR2 stimulation of intrinsic renal cells in the induction of immune-mediated glomerulonephritis. J Immunol (2006) 1.12
Chemokine receptor deficiency is associated with increased chemokine expression in the peripheral and central nervous systems and increased resistance to herpetic encephalitis. J Neuroimmunol (2005) 1.12
Synthesis of complement protein C3 in the kidney is an important mediator of local tissue injury. FASEB J (2007) 1.11
Loss of immunity-supported senescence enhances susceptibility to hepatocellular carcinogenesis and progression in Toll-like receptor 2-deficient mice. Hepatology (2013) 1.11
Attenuation of acute lung inflammation induced by cigarette smoke in CXCR3 knockout mice. Respir Res (2008) 1.10
Lack of beta-methylamino-l-alanine in brain from controls, AD, or Chamorros with PDC. Neurology (2005) 1.10