Published in Cancer Metastasis Rev on March 01, 2008
Microenvironmental regulation of metastasis. Nat Rev Cancer (2008) 15.76
Novel therapies for metastatic castrate-resistant prostate cancer. J Natl Cancer Inst (2011) 1.98
Bone metastasis: mechanisms and therapeutic opportunities. Nat Rev Endocrinol (2011) 1.66
Plumbagin, a medicinal plant-derived naphthoquinone, is a novel inhibitor of the growth and invasion of hormone-refractory prostate cancer. Cancer Res (2008) 1.39
Depletion of plasmacytoid dendritic cells inhibits tumor growth and prevents bone metastasis of breast cancer cells. J Immunol (2012) 1.36
Steps in prostate cancer progression that lead to bone metastasis. Int J Cancer (2011) 1.34
A microfluidic 3D in vitro model for specificity of breast cancer metastasis to bone. Biomaterials (2013) 1.34
Tumor-stroma co-evolution in prostate cancer progression and metastasis. Semin Cell Dev Biol (2009) 1.26
Mechanisms of bone metastases of breast cancer. Endocr Relat Cancer (2009) 1.25
Disseminated breast cancer cells acquire a highly malignant and aggressive metastatic phenotype during metastatic latency in the bone. PLoS One (2012) 1.15
Human 3D vascularized organotypic microfluidic assays to study breast cancer cell extravasation. Proc Natl Acad Sci U S A (2014) 1.13
BMPs and their clinical potentials. BMB Rep (2011) 1.11
Bone marrow-derived cathepsin K cleaves SPARC in bone metastasis. Am J Pathol (2009) 1.08
Cancer invasion and metastasis: interacting ecosystems. Virchows Arch (2009) 1.05
Adenosine and bone metabolism. Trends Endocrinol Metab (2013) 1.02
Individual and combined soy isoflavones exert differential effects on metastatic cancer progression. Clin Exp Metastasis (2010) 1.02
From prostate to bone: key players in prostate cancer bone metastasis. Cancers (Basel) (2011) 1.01
Cancer cell lines release glutamate into the extracellular environment. Clin Exp Metastasis (2009) 1.00
Basic fibroblast growth factor in the bone microenvironment enhances cell motility and invasion of Ewing's sarcoma family of tumours by activating the FGFR1-PI3K-Rac1 pathway. Br J Cancer (2010) 0.99
Activation of NF-kappa B signaling promotes growth of prostate cancer cells in bone. PLoS One (2013) 0.99
c-Myb regulates matrix metalloproteinases 1/9, and cathepsin D: implications for matrix-dependent breast cancer cell invasion and metastasis. Mol Cancer (2012) 0.98
Bone marrow endothelium-targeted therapeutics for metastatic breast cancer. J Control Release (2014) 0.96
Three-dimensional characterization of the vascular bed in bone metastasis of the rat by microcomputed tomography (MicroCT). PLoS One (2011) 0.95
In vivo tibial compression decreases osteolysis and tumor formation in a human metastatic breast cancer model. J Bone Miner Res (2013) 0.93
Paracrine factors produced by bone marrow stromal cells induce apoptosis and neuroendocrine differentiation in prostate cancer cells. Prostate (2011) 0.92
Bone marrow fat: linking adipocyte-induced inflammation with skeletal metastases. Cancer Metastasis Rev (2014) 0.92
Human antibodies targeting cell surface antigens overexpressed by the hormone refractory metastatic prostate cancer cells: ICAM-1 is a tumor antigen that mediates prostate cancer cell invasion. J Mol Med (Berl) (2009) 0.92
Imaging of bone metastasis: An update. World J Radiol (2015) 0.91
The hedgehog pathway conditions the bone microenvironment for osteolytic metastasis of breast cancer. Int J Breast Cancer (2011) 0.91
In vitro models of the metastatic cascade: from local invasion to extravasation. Drug Discov Today (2013) 0.91
ALCAM/CD166 is a TGF-β-responsive marker and functional regulator of prostate cancer metastasis to bone. Cancer Res (2014) 0.90
Localization of osteoblast inflammatory cytokines MCP-1 and VEGF to the matrix of the trabecula of the femur, a target area for metastatic breast cancer cell colonization. Clin Exp Metastasis (2010) 0.90
Elevated Pentraxin 3 in bone metastatic breast cancer is correlated with osteolytic function. Oncotarget (2014) 0.90
Hedgehog signaling in tumor cells facilitates osteoblast-enhanced osteolytic metastases. PLoS One (2012) 0.89
The chemokine receptor CX₃CR1 is directly involved in the arrest of breast cancer cells to the skeleton. Breast Cancer Res (2011) 0.89
Osteoblast-secreted collagen upregulates paracrine Sonic hedgehog signaling by prostate cancer cells and enhances osteoblast differentiation. Mol Cancer (2012) 0.88
Establishment and validation of an in vitro co-culture model to study the interactions between bone and prostate cancer cells. Clin Exp Metastasis (2009) 0.86
The frequency of osteolytic bone metastasis is determined by conditions of the soil, not the number of seeds; evidence from in vivo models of breast and prostate cancer. J Exp Clin Cancer Res (2015) 0.85
Selenium modifies the osteoblast inflammatory stress response to bone metastatic breast cancer. Carcinogenesis (2009) 0.85
Enhancement of osteoclastogenic activity in osteolytic prostate cancer cells by physical contact with osteoblasts. Br J Cancer (2011) 0.85
Osteoblasts modulate Ca2+ signaling in bone-metastatic prostate and breast cancer cells. Clin Exp Metastasis (2009) 0.84
The alpha-receptor for platelet-derived growth factor confers bone-metastatic potential to prostate cancer cells by ligand- and dimerization-independent mechanisms. Cancer Res (2010) 0.84
Infection-induced changes in hematopoiesis. J Immunol (2014) 0.83
Curcumin blocks CCL2-induced adhesion, motility and invasion, in part, through down-regulation of CCL2 expression and proteolytic activity. Int J Oncol (2009) 0.82
Pathobiology and management of prostate cancer-induced bone pain: recent insights and future treatments. Inflammopharmacology (2013) 0.82
An integrated computational model of the bone microenvironment in bone-metastatic prostate cancer. Cancer Res (2014) 0.82
Pharmacological methyl group donors block skeletal metastasis in vitro and in vivo. Br J Pharmacol (2015) 0.81
The use of chemokine-releasing tissue engineering scaffolds in a model of inflammatory response-mediated melanoma cancer metastasis. Biomaterials (2011) 0.81
Combined treatment with paclitaxel and suramin prevents the development of metastasis by inhibiting metastatic colonization of circulating tumor cells. Clin Exp Metastasis (2014) 0.80
The clone wars - revenge of the metastatic rogue state: the sarcoma paradigm. Front Oncol (2012) 0.79
Blood clot formation does not affect metastasis formation or tumor growth in a murine model of breast cancer. PLoS One (2014) 0.76
Chemical and Biochemical Basis of Cell-Bone Matrix Interaction in Health and Disease. Curr Chem Biol (2009) 0.75
Extracellular Matrix Rigidity-dependent Sphingosine-1-phosphate Secretion Regulates Metastatic Cancer Cell Invasion and Adhesion. Sci Rep (2016) 0.75
Vascular niches for disseminated tumour cells in bone. J Bone Oncol (2016) 0.75
Expression of Cadherin-17 Promotes Metastasis in a Highly Bone Marrow Metastatic Murine Breast Cancer Model. Biomed Res Int (2017) 0.75
A novel microfluidic platform for studying mammalian cell chemotaxis in different oxygen environments under zero-flow conditions. Biomicrofluidics (2015) 0.75
Detecting Tumor Metastases: The Road to Therapy Starts Here. Adv Cancer Res (2016) 0.75
Current concepts in bone metastasis, contemporary therapeutic strategies and ongoing clinical trials. J Exp Clin Cancer Res (2017) 0.75
Development and characterization of murine models of medulloblastoma extraneural growth in bone. Clin Exp Metastasis (2013) 0.75
Kinetics of metastatic breast cancer cell trafficking in bone. Clin Cancer Res (2006) 1.42
Influence of substratum surface chemistry/energy and topography on the human fetal osteoblastic cell line hFOB 1.19: Phenotypic and genotypic responses observed in vitro. Biomaterials (2007) 1.38
A small molecule antagonist of the alpha(v)beta3 integrin suppresses MDA-MB-435 skeletal metastasis. Clin Exp Metastasis (2004) 1.23
The skeleton as a unique environment for breast cancer cells. Clin Exp Metastasis (2003) 1.17
Breast cancer metastasis to the bone: mechanisms of bone loss. Breast Cancer Res (2010) 1.15
Metastatic breast cancer induces an osteoblast inflammatory response. Exp Cell Res (2007) 1.03
Metastatic breast cancer cells suppress osteoblast adhesion and differentiation. Clin Exp Metastasis (2004) 1.03
Breast cancer cells induce osteoblast apoptosis: a possible contributor to bone degradation. J Cell Biochem (2004) 0.97
Dietary selenium supplementation modifies breast tumor growth and metastasis. Int J Cancer (2013) 0.96
Osteoblasts are a major source of inflammatory cytokines in the tumor microenvironment of bone metastatic breast cancer. J Cell Biochem (2010) 0.94
Dynamic interaction between breast cancer cells and osteoblastic tissue: comparison of two- and three-dimensional cultures. J Cell Physiol (2011) 0.92
Exercise and lymphocyte activation following chemotherapy for breast cancer. Med Sci Sports Exerc (2005) 0.91
Localization of osteoblast inflammatory cytokines MCP-1 and VEGF to the matrix of the trabecula of the femur, a target area for metastatic breast cancer cell colonization. Clin Exp Metastasis (2010) 0.90
Neuroendocrine-immune interactions and responses to exercise. Sports Med (2011) 0.89
Changes in Cytokines of the Bone Microenvironment during Breast Cancer Metastasis. Int J Breast Cancer (2012) 0.89
Roles of osteonectin in the migration of breast cancer cells into bone. J Cell Biochem (2006) 0.87
Metastatic breast cancer cells colonize and degrade three-dimensional osteoblastic tissue in vitro. Clin Exp Metastasis (2008) 0.86
Ex-vivo analysis of the bone microenvironment in bone metastatic breast cancer. J Mammary Gland Biol Neoplasia (2009) 0.86
Dormancy and growth of metastatic breast cancer cells in a bone-like microenvironment. Clin Exp Metastasis (2015) 0.86
Release of cytokines and hemodynamic instability during the reperfusion of a liver graft. Liver Transpl (2011) 0.85
Expression of Na(+)/Ca(2+) exchanger isoforms (NCX1 and NCX3) and plasma membrane Ca(2+) ATPase during osteoblast differentiation. J Cell Biochem (2002) 0.85
Selenium modifies the osteoblast inflammatory stress response to bone metastatic breast cancer. Carcinogenesis (2009) 0.85
Is selenium a potential treatment for cancer metastasis? Nutrients (2013) 0.84
Evaluation of bone-derived and marrow-derived vascular endothelial cells by microarray analysis. J Cell Biochem (2007) 0.83
Leukocyte β2-adrenergic receptor expression in response to resistance exercise. Med Sci Sports Exerc (2011) 0.83
Extended-term culture of bone cells in a compartmentalized bioreactor. Tissue Eng (2006) 0.83
In vitro mimics of bone remodeling and the vicious cycle of cancer in bone. J Cell Physiol (2014) 0.81
Cytokines secreted by bone-metastatic breast cancer cells alter the expression pattern of f-actin and reduce focal adhesion plaques in osteoblasts through PI3K. Exp Cell Res (2005) 0.81
Short-term zinc deficiency inhibits chondrocyte proliferation and induces cell apoptosis in the epiphyseal growth plate of young chickens. J Nutr (2002) 0.80
Osteoblast-conditioned media influence the expression of E-selectin on bone-derived vascular endothelial cells. J Cell Biochem (2006) 0.80
Osteogenesis in vitro: from pre-osteoblasts to osteocytes: a contribution from the Osteobiology Research Group, The Pennsylvania State University. In Vitro Cell Dev Biol Anim (2009) 0.80
Chronic resistance training in women potentiates growth hormone in vivo bioactivity: characterization of molecular mass variants. Am J Physiol Endocrinol Metab (2006) 0.80
NCX3 is a major functional isoform of the sodium-calcium exchanger in osteoblasts. J Cell Biochem (2008) 0.79
Nutritional status predicts primary subclasses of T cells and the lymphocyte proliferation response in healthy older women. J Nutr (2005) 0.79
Metastasis Research Society-American Association For Cancer Research Joint Conference on Metastasis. Cancer Res (2008) 0.79
Association between plasma cyclic guanosine monophosphate levels and hemodynamic instability during liver transplantation. Liver Transpl (2013) 0.78
Glucocorticoid receptor expression on human B cells in response to acute heavy resistance exercise. Neuroimmunomodulation (2011) 0.76
Pre-osteoblastic MC3T3-E1 cells promote breast cancer growth in bone in a murine xenograft model. Chin J Cancer (2011) 0.76
Maternal selenium nutrition and neonatal immune system development. Biol Neonate (2002) 0.76
Exercise increases prolactin-receptor expression on human lymphocytes. J Appl Physiol (1985) (2002) 0.76
Effects of resistance training on resting immune parameters in women. Eur J Appl Physiol (2002) 0.76
Proenkephalin peptide F immunoreactivity in different circulatory biocompartments after exercise. Peptides (2006) 0.75
Influence of oral contraceptive use on growth hormone in vivo bioactivity following resistance exercise: responses of molecular mass variants. Growth Horm IGF Res (2007) 0.75
Responses of plasma proenkephalin peptide F in rats following 14 days of spaceflight. Aviat Space Environ Med (2004) 0.75
Study of cellular adhesion with scanning acoustic microscopy. IEEE Trans Ultrason Ferroelectr Freq Control (2007) 0.75
Inter- and intra-individual variation in tests of cell-mediated immunity in young and old women. Mech Ageing Dev (2003) 0.75
Responses of proenkephalin Peptide F to aerobic exercise stress in the plasma and white blood cell biocompartments. Peptides (2013) 0.75
The effect of donor age on the sensitivity of osteoblasts to the proliferative effects of TGF(beta) and 1,25(OH(2)) vitamin D(3). Life Sci (2002) 0.75