Published in J Biol Chem on January 16, 2008
Polycomb repressive complex 2 is dispensable for maintenance of embryonic stem cell pluripotency. Stem Cells (2008) 3.81
Epigenetic dynamics of stem cells and cell lineage commitment: digging Waddington's canal. Nat Rev Mol Cell Biol (2009) 3.12
RYBP-PRC1 complexes mediate H2A ubiquitylation at polycomb target sites independently of PRC2 and H3K27me3. Cell (2012) 2.77
Regulation of stem cell pluripotency and differentiation involves a mutual regulatory circuit of the NANOG, OCT4, and SOX2 pluripotency transcription factors with polycomb repressive complexes and stem cell microRNAs. Stem Cells Dev (2009) 2.40
Dax1 binds to Oct3/4 and inhibits its transcriptional activity in embryonic stem cells. Mol Cell Biol (2009) 1.20
OstemiR: a novel panel of microRNA biomarkers in osteoblastic and osteocytic differentiation from mesencymal stem cells. PLoS One (2013) 1.09
Polycomblike 2 facilitates the recruitment of PRC2 Polycomb group complexes to the inactive X chromosome and to target loci in embryonic stem cells. Development (2011) 1.08
The Oct4 protein: more than a magic stemness marker. Am J Stem Cells (2014) 1.05
Absolute requirement for STAT3 function in small-intestine crypt stem cell survival. Cell Death Differ (2011) 1.02
Eed/Sox2 regulatory loop controls ES cell self-renewal through histone methylation and acetylation. EMBO J (2011) 0.99
LIF-dependent signaling: new pieces in the Lego. Stem Cell Rev (2012) 0.98
Inhibition of STAT3, FAK and Src mediated signaling reduces cancer stem cell load, tumorigenic potential and metastasis in breast cancer. Sci Rep (2015) 0.91
Endoribonuclease L (RNase L) regulates the myogenic and adipogenic potential of myogenic cells. PLoS One (2009) 0.88
The interaction of PRC2 with RNA or chromatin is mutually antagonistic. Genome Res (2016) 0.88
JAK-STAT3 and somatic cell reprogramming. JAKSTAT (2013) 0.88
Induced pluripotent stem cells: emerging techniques for nuclear reprogramming. Antioxid Redox Signal (2011) 0.85
Molecular basis of Mammalian embryonic stem cell pluripotency and self-renewal. Acta Naturae (2010) 0.81
ETS-related transcription factors ETV4 and ETV5 are involved in proliferation and induction of differentiation-associated genes in embryonic stem (ES) cells. J Biol Chem (2015) 0.81
Genome-wide shRNA screening to identify factors mediating Gata6 repression in mouse embryonic stem cells. Development (2013) 0.79
MicroRNA-323-3p regulates the activity of polycomb repressive complex 2 (PRC2) via targeting the mRNA of embryonic ectoderm development (Eed) gene in mouse embryonic stem cells. J Biol Chem (2013) 0.78
Polycomb group gene expression in the sea urchin. Dev Dyn (2008) 0.77
Tunicate cytostatic factor TC14-3 induces a polycomb group gene and histone modification through Ca(2+) binding and protein dimerization. BMC Cell Biol (2012) 0.75
Kruppel-like factor 5 is not required for K-RasG12D lung tumorigenesis, but represses ABCG2 expression and is associated with better disease-specific survival. Am J Pathol (2010) 0.75
Cdh1-APC controls axonal growth and patterning in the mammalian brain. Science (2004) 3.44
RYBP-PRC1 complexes mediate H2A ubiquitylation at polycomb target sites independently of PRC2 and H3K27me3. Cell (2012) 2.77
β-catenin enhances Oct-4 activity and reinforces pluripotency through a TCF-independent mechanism. Cell Stem Cell (2011) 2.07
Gene expression profiling of embryo-derived stem cells reveals candidate genes associated with pluripotency and lineage specificity. Genome Res (2002) 1.77
A novel chordin-like BMP inhibitor, CHL2, expressed preferentially in chondrocytes of developing cartilage and osteoarthritic joint cartilage. Development (2003) 1.71
Beta-catenin up-regulates Nanog expression through interaction with Oct-3/4 in embryonic stem cells. Biochem Biophys Res Commun (2006) 1.66
Randomized, double-blind, placebo- and propiverine-controlled trial of the once-daily antimuscarinic agent solifenacin in Japanese patients with overactive bladder. BJU Int (2007) 1.61
Acute hemodynamic effects of adaptive servo-ventilation in patients with heart failure. Circ J (2013) 1.53
Inhibitors of Ras/Raf-1 interaction identified by two-hybrid screening revert Ras-dependent transformation phenotypes in human cancer cells. Proc Natl Acad Sci U S A (2002) 1.52
A core paired-type and POU homeodomain-containing transcription factor program drives retinal bipolar cell gene expression. J Neurosci (2008) 1.46
Medical triage and legal protection in Japan. Lancet (2002) 1.45
alpha-Aminoadipate induces progenitor cell properties of Müller glia in adult mice. Invest Ophthalmol Vis Sci (2008) 1.37
Functional screening identifies a microRNA, miR-491 that induces apoptosis by targeting Bcl-X(L) in colorectal cancer cells. Int J Cancer (2010) 1.27
Identification of the nucleocytoplasmic shuttling sequence of heterogeneous nuclear ribonucleoprotein D-like protein JKTBP and its interaction with mRNA. J Biol Chem (2001) 1.25
Dax1 binds to Oct3/4 and inhibits its transcriptional activity in embryonic stem cells. Mol Cell Biol (2009) 1.20
CD9 is associated with leukemia inhibitory factor-mediated maintenance of embryonic stem cells. Mol Biol Cell (2002) 1.17
Protection of the retina by rapid diffusion of hydrogen: administration of hydrogen-loaded eye drops in retinal ischemia-reperfusion injury. Invest Ophthalmol Vis Sci (2009) 1.13
Epigenetic regulation and molecular characterization of C/EBPalpha in pancreatic cancer cells. Int J Cancer (2009) 1.12
Involvement of Ras in extraembryonic endoderm differentiation of embryonic stem cells. Biochem Biophys Res Commun (2004) 1.08
Dose effect on intramuscular metabolic stress during low-intensity resistance exercise with blood flow restriction. J Appl Physiol (1985) (2010) 1.05
Congenital atrial standstill associated with coinheritance of a novel SCN5A mutation and connexin 40 polymorphisms. Heart Rhythm (2005) 1.04
Identification of Zfp-57 as a downstream molecule of STAT3 and Oct-3/4 in embryonic stem cells. Biochem Biophys Res Commun (2005) 1.02
Overexpression of glutathione peroxidase attenuates myocardial remodeling and preserves diastolic function in diabetic heart. Am J Physiol Heart Circ Physiol (2006) 1.02
Stat3 up-regulates expression of nicotinamide N-methyltransferase in human cancer cells. J Cancer Res Clin Oncol (2007) 1.02
Expression profiling in transgenic FVB/N embryonic stem cells overexpressing STAT3. BMC Dev Biol (2008) 1.02
GABPalpha regulates Oct-3/4 expression in mouse embryonic stem cells. Biochem Biophys Res Commun (2006) 1.02
Stat3-dependent induction of BATF in M1 mouse myeloid leukemia cells. Oncogene (2002) 0.99
Molecular allelokaryotyping of T-cell prolymphocytic leukemia cells with high density single nucleotide polymorphism arrays identifies novel common genomic lesions and acquired uniparental disomy. Haematologica (2009) 0.99
Eed/Sox2 regulatory loop controls ES cell self-renewal through histone methylation and acetylation. EMBO J (2011) 0.99
Reciprocal inhibition between MyoD and STAT3 in the regulation of growth and differentiation of myoblasts. J Biol Chem (2003) 0.99
Conditional expression of the TVA receptor allows clonal analysis of descendents from Cre-expressing progenitor cells. Dev Biol (2011) 0.98
Emergency abdominal surgery for sigmoid mesocolic hernia. Am J Emerg Med (2002) 0.98
Stem cell-specific expression of Dax1 is conferred by STAT3 and Oct3/4 in embryonic stem cells. Biochem Biophys Res Commun (2008) 0.98
Angiotensin II type 1 receptor blocker attenuates myocardial remodeling and preserves diastolic function in diabetic heart. Hypertens Res (2007) 0.96
Tool-use learning induces BDNF expression in a selective portion of monkey anterior parietal cortex. Brain Res Mol Brain Res (2002) 0.96
Zinc finger protein sall2 is not essential for embryonic and kidney development. Mol Cell Biol (2003) 0.95
H(2) gas improves functional outcome after cardiac arrest to an extent comparable to therapeutic hypothermia in a rat model. J Am Heart Assoc (2012) 0.95
STAT3 down-regulates the expression of cyclin D during liver development. J Biol Chem (2002) 0.95
Intramuscular metabolism during low-intensity resistance exercise with blood flow restriction. J Appl Physiol (1985) (2009) 0.95
Nonsteroidal anti-inflammatory drugs suppress glioma via 15-hydroxyprostaglandin dehydrogenase. Cancer Res (2008) 0.94
Inecalcitol, an analog of 1α,25(OH)(2) D(3) , induces growth arrest of androgen-dependent prostate cancer cells. Int J Cancer (2011) 0.92
Genomic profiling of adult acute lymphoblastic leukemia by single nucleotide polymorphism oligonucleotide microarray and comparison to pediatric acute lymphoblastic leukemia. Haematologica (2010) 0.91
Anti-(Raf-1) RNA aptamers that inhibit Ras-induced Raf-1 activation. Eur J Biochem (2002) 0.90
Evidence-based medicine in Japan. Lancet (2005) 0.90
LSSIG is a novel murine leukocyte-specific GPCR that is induced by the activation of STAT3. Blood (2002) 0.90
Oxidative stress impairs insulin signal in skeletal muscle and causes insulin resistance in postinfarct heart failure. Am J Physiol Heart Circ Physiol (2011) 0.90
Molecular hydrogen protects chondrocytes from oxidative stress and indirectly alters gene expressions through reducing peroxynitrite derived from nitric oxide. Med Gas Res (2011) 0.90
Down-regulation of a novel gene, DRLM, in human liver malignancy from 4q22 that encodes a NAP-like protein. Gene (2002) 0.89
Tool-use learning selectively induces expression of brain-derived neurotrophic factor, its receptor trkB, and neurotrophin 3 in the intraparietal multisensorycortex of monkeys. Brain Res Cogn Brain Res (2002) 0.89
Hyperuricemia predicts adverse outcomes in patients with heart failure. Int J Cardiol (2010) 0.89
Advanced gastric glandular-endocrine cell carcinoma with 1-year survival after gastrectomy. Gastric Cancer (2000) 0.88
Dax1 associates with Esrrb and regulates its function in embryonic stem cells. Mol Cell Biol (2013) 0.88
Angiotensin II-induced reduction in exercise capacity is associated with increased oxidative stress in skeletal muscle. Am J Physiol Heart Circ Physiol (2011) 0.88
Effect of multiple set on intramuscular metabolic stress during low-intensity resistance exercise with blood flow restriction. Eur J Appl Physiol (2012) 0.88
Efficacy of solifenacin on nocturia in Japanese patients with overactive bladder: impact on sleep evaluated by bladder diary. J Urol (2011) 0.88
Increased myocardial NAD(P)H oxidase-derived superoxide causes the exacerbation of postinfarct heart failure in type 2 diabetes. Am J Physiol Heart Circ Physiol (2009) 0.87
Ras signaling directs endothelial specification of VEGFR2+ vascular progenitor cells. J Cell Biol (2008) 0.87
Synergy of Eed and Tsix in the repression of Xist gene and X-chromosome inactivation. EMBO J (2008) 0.86
Low-intensity exercise can increase muscle mass and strength proportionally to enhanced metabolic stress under ischemic conditions. J Appl Physiol (1985) (2012) 0.85
Valproic acid-inducible Arl4D and cytohesin-2/ARNO, acting through the downstream Arf6, regulate neurite outgrowth in N1E-115 cells. Exp Cell Res (2009) 0.85
Involvement of telomerase reverse transcriptase in heterochromatin maintenance. Mol Cell Biol (2014) 0.85
Combination of exercise training and diet restriction normalizes limited exercise capacity and impaired skeletal muscle function in diet-induced diabetic mice. Endocrinology (2013) 0.85
High oxygen condition facilitates the differentiation of mouse and human pluripotent stem cells into pancreatic progenitors and insulin-producing cells. J Biol Chem (2014) 0.84
Differential expression of multiple isoforms of the ELKS mRNAs involved in a papillary thyroid carcinoma. Genes Chromosomes Cancer (2002) 0.83
Angiotensin II can directly induce mitochondrial dysfunction, decrease oxidative fibre number and induce atrophy in mouse hindlimb skeletal muscle. Exp Physiol (2015) 0.83
Pancreatic T-cell lymphoma with high level of soluble interleukin-2 receptor. J Gastroenterol (2002) 0.83
Food conditions, competitive regime, and female social relationships in Japanese macaques: within-population variation on Yakushima. Primates (2007) 0.83
Predictive factors for the effect of the α1-D/A adrenoceptor antagonist naftopidil on subjective and objective criteria in patients with neurogenic lower urinary tract dysfunction. BJU Int (2010) 0.83
Alteration of histone tail modifications in the Xist locus in wild-type and Tsix-mutant male embryonic stem cells during differentiation. Exp Anim (2008) 0.81
Dynamic CCAAT/enhancer binding protein-associated changes of DNA methylation in the angiotensinogen gene. Hypertension (2013) 0.81
Identification and relative quantitation of an orphan G-protein coupled receptor SREB2 (GPR85) protein in tissue using a linear ion trap mass spectrometer. J Proteome Res (2011) 0.80