Published in Exp Hematol on January 30, 2008
Apremilast, a cAMP phosphodiesterase-4 inhibitor, demonstrates anti-inflammatory activity in vitro and in a model of psoriasis. Br J Pharmacol (2009) 1.89
Role of macrophage inflammatory protein (MIP)-1α/CCL3 in leukemogenesis. Mol Cell Oncol (2014) 0.76
Exendin-4 Ameliorates Lipotoxicity-induced Glomerular Endothelial Cell Injury by Improving ABC Transporter A1-mediated Cholesterol Efflux in Diabetic apoE Knockout Mice. J Biol Chem (2016) 0.75
A human gut microbial gene catalogue established by metagenomic sequencing. Nature (2010) 43.63
A metagenome-wide association study of gut microbiota in type 2 diabetes. Nature (2012) 11.68
Open-source genomic analysis of Shiga-toxin-producing E. coli O104:H4. N Engl J Med (2011) 7.11
Richness of human gut microbiome correlates with metabolic markers. Nature (2013) 6.93
The genome sequence and structure of rice chromosome 1. Nature (2002) 4.99
Calmodulin-kinases: modulators of neuronal development and plasticity. Neuron (2008) 3.14
Metagenomic species profiling using universal phylogenetic marker genes. Nat Methods (2013) 2.51
Clinical characteristics of 26 human cases of highly pathogenic avian influenza A (H5N1) virus infection in China. PLoS One (2008) 2.28
STO-609, a specific inhibitor of the Ca(2+)/calmodulin-dependent protein kinase kinase. J Biol Chem (2002) 2.28
Comparison of central blood pressure and cardio-ankle vascular index for association with cardiac function in treated hypertensive patients. Hypertens Res (2009) 2.07
Mutation of the beta1-tubulin gene associated with congenital macrothrombocytopenia affecting microtubule assembly. Blood (2008) 1.73
A mutant high-density lipoprotein receptor inhibits proliferation of human breast cancer cells. Cancer Res (2004) 1.67
GABAergic inhibition of histaminergic neurons regulates active waking but not the sleep-wake switch or propofol-induced loss of consciousness. J Neurosci (2012) 1.67
MOCAT: a metagenomics assembly and gene prediction toolkit. PLoS One (2012) 1.64
Regulation of axonal extension and growth cone motility by calmodulin-dependent protein kinase I. J Neurosci (2004) 1.57
The antidiabetic drug metformin inhibits gastric cancer cell proliferation in vitro and in vivo. Mol Cancer Ther (2012) 1.57
Outcome of 154 patients with severe aplastic anemia who received transplants from unrelated donors: the Japan Marrow Donor Program. Blood (2002) 1.55
Subcapsular renal haematoma after holmium:yttrium-aluminum-garnet laser ureterolithotripsy. BJU Int (2011) 1.55
Systemic candesartan reduces brain angiotensin II via downregulation of brain renin-angiotensin system. Hypertens Res (2009) 1.51
ACTN1 mutations cause congenital macrothrombocytopenia. Am J Hum Genet (2013) 1.49
Annexin A2 expression and phosphorylation are up-regulated in hepatocellular carcinoma. Int J Oncol (2008) 1.33
Evola: Ortholog database of all human genes in H-InvDB with manual curation of phylogenetic trees. Nucleic Acids Res (2007) 1.32
Analysis of CaM-kinase signaling in cells. Cell Calcium (2011) 1.30
Long-term efficacy of hematopoietic stem cell transplantation on brain involvement in patients with mucopolysaccharidosis type II: a nationwide survey in Japan. Mol Genet Metab (2012) 1.30
Risk-stratified therapy and the intensive use of cytarabine improves the outcome in childhood acute myeloid leukemia: the AML99 trial from the Japanese Childhood AML Cooperative Study Group. J Clin Oncol (2009) 1.26
ATF3 suppresses metastasis of bladder cancer by regulating gelsolin-mediated remodeling of the actin cytoskeleton. Cancer Res (2013) 1.25
A modeling study of coarse particulate matter pollution in Beijing: regional source contributions and control implications for the 2008 Summer Olympics. J Air Waste Manag Assoc (2008) 1.24
IL-17A produced by γδ T cells promotes tumor growth in hepatocellular carcinoma. Cancer Res (2014) 1.24
Methylation profiles of thirty four promoter-CpG islands and concordant methylation behaviours of sixteen genes that may contribute to carcinogenesis of astrocytoma. BMC Cancer (2004) 1.23
A CaMK cascade activates CRE-mediated transcription in neurons of Caenorhabditis elegans. EMBO Rep (2002) 1.22
Widespread horizontal gene transfer from circular single-stranded DNA viruses to eukaryotic genomes. BMC Evol Biol (2011) 1.18
FBXW7 and NOTCH1 mutations in childhood T cell acute lymphoblastic leukaemia and T cell non-Hodgkin lymphoma. Br J Haematol (2009) 1.12
Expression of human scavenger receptor B1 on and in human platelets. Arterioscler Thromb Vasc Biol (2003) 1.10
Breast cancer cells expressing stem cell markers CD44+ CD24 lo are eliminated by Numb-1 peptide-activated T cells. Cancer Immunol Immunother (2008) 1.10
Phosphorylation of Numb family proteins. Possible involvement of Ca2+/calmodulin-dependent protein kinases. J Biol Chem (2005) 1.09
Lineage switch from precursor B cell acute lymphoblastic leukemia to acute monocytic leukemia at relapse. Int J Clin Oncol (2010) 1.08
Hepatitis B vaccination of newborn infants in rural China: evaluation of a village-based, out-of-cold-chain delivery strategy. Bull World Health Organ (2007) 1.08
Improved treatment results of children with B-cell non-Hodgkin lymphoma: a report from the Japanese Pediatric Leukemia/Lymphoma Study Group B-NHL03 study. Pediatr Blood Cancer (2014) 1.07
Discrete functions of M2a and M2c macrophage subsets determine their relative efficacy in treating chronic kidney disease. Kidney Int (2013) 1.07
Phosphatase activity, trimerization, and the C-terminal polybasic region are all required for PRL1-mediated cell growth and migration. J Biol Chem (2007) 1.07
Menin, a product of the MENI gene, binds to estrogen receptor to enhance its activity in breast cancer cells: possibility of a novel predictive factor for tamoxifen resistance. Breast Cancer Res Treat (2009) 1.07
The antidiabetic drug metformin inhibits the proliferation of bladder cancer cells in vitro and in vivo. Int J Mol Sci (2013) 1.05
Loss of downregulated in adenoma (DRA) impairs mucosal HCO3(-) secretion in murine ileocolonic inflammation. Inflamm Bowel Dis (2011) 1.05
Characterization of murine macrophages from bone marrow, spleen and peritoneum. BMC Immunol (2013) 1.05
Eya1 controls cell polarity, spindle orientation, cell fate and Notch signaling in distal embryonic lung epithelium. Development (2011) 1.04
Idiopathic non-specific interstitial pneumonia: as an "autoimmune interstitial pneumonia". Respir Med (2005) 1.04
Loss of PDZ-adaptor protein NHERF2 affects membrane localization and cGMP- and [Ca2+]- but not cAMP-dependent regulation of Na+/H+ exchanger 3 in murine intestine. J Physiol (2010) 1.04
Prospective study of a pirarubicin, intermediate-dose cytarabine, and etoposide regimen in children with Down syndrome and acute myeloid leukemia: the Japanese Childhood AML Cooperative Study Group. J Clin Oncol (2007) 1.03
Control of secretion by temporal patterns of action potentials in adrenal chromaffin cells. J Neurosci (2003) 1.02
Epstein-Barr virus-associated B-cell lymphoma in a patient with DNA ligase IV (LIG4) syndrome. Am J Med Genet A (2007) 1.02
Is cervical disc arthroplasty superior to fusion for treatment of symptomatic cervical disc disease? A meta-analysis. Clin Orthop Relat Res (2013) 1.02
A single amino acid difference between alpha and beta Ca2+/calmodulin-dependent protein kinase kinase dictates sensitivity to the specific inhibitor, STO-609. J Biol Chem (2003) 1.01
An early response transcription factor, Egr-1, enhances insulin resistance in type 2 diabetes with chronic hyperinsulinism. J Biol Chem (2011) 1.00
Discovery of a novel series of inhibitors of lymphoid tyrosine phosphatase with activity in human T cells. J Med Chem (2011) 1.00
Epidemiology and treatment outcome of invasive fungal infections in patients with hematological malignancies. Int J Hematol (2012) 0.99
Protective effects of chlorogenic acid on acute hepatotoxicity induced by lipopolysaccharide in mice. Inflamm Res (2010) 0.99
Activation of SAD kinase by Ca2+/calmodulin-dependent protein kinase kinase. Biochemistry (2008) 0.99
Pathological findings of bronchiectases caused by Mycobacterium avium intracellulare complex. Respir Med (2003) 0.99
Correlation of Skp2 with carcinogenesis, invasion, metastasis, and prognosis in colorectal tumors. Int J Oncol (2004) 0.99
Dynamics and Stabilization of the Human Gut Microbiome during the First Year of Life. Cell Host Microbe (2015) 0.99
Antitumor effect of metformin in esophageal cancer: in vitro study. Int J Oncol (2012) 0.99
Human microRNAs originated from two periods at accelerated rates in mammalian evolution. Mol Biol Evol (2012) 0.98
Perilipin regulates the thermogenic actions of norepinephrine in brown adipose tissue. J Lipid Res (2007) 0.98
Clinical impact of HLA-DR15, a minor population of paroxysmal nocturnal haemoglobinuria-type cells, and an aplastic anaemia-associated autoantibody in children with acquired aplastic anaemia. Br J Haematol (2008) 0.98
SHP2 is a target of the immunosuppressant tautomycetin. Chem Biol (2011) 0.98
Biologic activity of RANTES in apheresis PLT concentrates and its involvement in nonhemolytic transfusion reactions. Transfusion (2003) 0.97
Logistic regression model for predicting stone-free rate after minimally invasive percutaneous nephrolithotomy. Urology (2011) 0.96
DRIFT study on cerium-tungsten/titania catalyst for selective catalytic reduction of NOx with NH3. Environ Sci Technol (2010) 0.96
Fiber supercapacitors utilizing pen ink for flexible/wearable energy storage. Adv Mater (2012) 0.95
A 94-GHz millimeter-wave sensor for speech signal acquisition. Sensors (Basel) (2013) 0.95
A non-synonymous polymorphism Thr115Met in the EpCAM gene is associated with an increased risk of breast cancer in Chinese population. Breast Cancer Res Treat (2010) 0.95
Chronic graft-versus-host disease following umbilical cord blood transplantation: retrospective survey involving 1072 patients in Japan. Blood (2008) 0.95
Infrapatellar fat pad may be with tendon repairing ability and closely related with the developing process of patella Baja. Med Hypotheses (2011) 0.95
Identification of a novel erythroid-specific enhancer for the ALAS2 gene and its loss-of-function mutation which is associated with congenital sideroblastic anemia. Haematologica (2013) 0.95
RNAi knockdown of Oryza sativa root meander curling gene led to altered root development and coiling which were mediated by jasmonic acid signalling in rice. Plant Cell Environ (2007) 0.94
Mechanism of the generation of autonomous activity of Ca2+/calmodulin-dependent protein kinase IV. J Biol Chem (2004) 0.94
Cyclin B1, unlike cyclin G1, increases significantly during colorectal carcinogenesis and during later metastasis to lymph nodes. Int J Oncol (2003) 0.93
Over-expression of OsAGAP, an ARF-GAP, interferes with auxin influx, vesicle trafficking and root development. Plant J (2006) 0.93
Haematopoietic stem cell transplantation for relapsed or refractory anaplastic large cell lymphoma: a study of children and adolescents in Japan. Br J Haematol (2014) 0.93
Cadmium is a potent inhibitor of PPM phosphatases and targets the M1 binding site. Sci Rep (2013) 0.92
Identification of intracellular target proteins of the calcium-signaling protein S100A12. Eur J Biochem (2004) 0.92
Interaction of S100 proteins with the antiallergic drugs, olopatadine, amlexanox, and cromolyn: identification of putative drug binding sites on S100A1 protein. Biochem Biophys Res Commun (2002) 0.92
Wiskott-Aldrich syndrome presenting with a clinical picture mimicking juvenile myelomonocytic leukaemia. Pediatr Blood Cancer (2012) 0.92
The multiple endocrine neoplasia type 1 gene product, menin, inhibits insulin production in rat insulinoma cells. Endocrinology (2002) 0.92
Structural and functional analysis of a 0.5-Mb chicken region orthologous to the imprinted mammalian Ascl2/Mash2-Igf2-H19 region. Genome Res (2004) 0.91