Published in Endocrinology on February 28, 2008
MLL2 is required in oocytes for bulk histone 3 lysine 4 trimethylation and transcriptional silencing. PLoS Biol (2010) 1.68
Mouse oocyte control of granulosa cell development and function: paracrine regulation of cumulus cell metabolism. Semin Reprod Med (2009) 1.61
Integral role of GDF-9 and BMP-15 in ovarian function. Mol Reprod Dev (2011) 1.26
Revisiting oocyte-somatic cell interactions: in search of novel intrafollicular predictors and regulators of oocyte developmental competence. Mol Hum Reprod (2008) 1.00
Transcriptome profiling of sheep granulosa cells and oocytes during early follicular development obtained by laser capture microdissection. BMC Genomics (2011) 0.93
Mouse oocytes enable LH-induced maturation of the cumulus-oocyte complex via promoting EGF receptor-dependent signaling. Mol Endocrinol (2010) 0.93
Estrogen promotes the development of mouse cumulus cells in coordination with oocyte-derived GDF9 and BMP15. Mol Endocrinol (2010) 0.91
Does bone morphogenetic protein 6 (BMP6) affect female fertility in the mouse? Biol Reprod (2010) 0.86
Bone morphogenetic protein signaling transcription factor (SMAD) function in granulosa cells. Mol Cell Endocrinol (2011) 0.84
New insights into ovarian function. Handb Exp Pharmacol (2010) 0.81
Overexpression of Uromodulin-like1 accelerates follicle depletion and subsequent ovarian degeneration. Cell Death Dis (2012) 0.78
Genetic associations with diminished ovarian reserve: a systematic review of the literature. J Assist Reprod Genet (2014) 0.78
Positive selection in bone morphogenetic protein 15 targets a natural mutation associated with primary ovarian insufficiency in human. PLoS One (2013) 0.77
Interaction between gonadotropin-releasing hormone and bone morphogenetic protein-6 and -7 signaling in LβT2 gonadotrope cells. Mol Cell Endocrinol (2011) 0.77
Tribulus terrestris Alters the Expression of Growth Differentiation Factor 9 and Bone Morphogenetic Protein 15 in Rabbit Ovaries of Mothers and F1 Female Offspring. PLoS One (2016) 0.75
Association between BMP15 Gene Polymorphism and Reproduction Traits and Its Tissues Expression Characteristics in Chicken. PLoS One (2015) 0.75
Zp3-cre, a transgenic mouse line for the activation or inactivation of loxP-flanked target genes specifically in the female germ line. Curr Biol (1997) 4.46
Growth differentiation factor-9 is required during early ovarian folliculogenesis. Nature (1996) 4.34
A longitudinal study of estrous cyclicity in aging C57BL/6J mice: I. Cycle frequency, length and vaginal cytology. Biol Reprod (1982) 3.28
Mutations in an oocyte-derived growth factor gene (BMP15) cause increased ovulation rate and infertility in a dosage-sensitive manner. Nat Genet (2000) 3.05
Synergistic roles of bone morphogenetic protein 15 and growth differentiation factor 9 in ovarian function. Mol Endocrinol (2001) 2.91
Efficient gene activation in mammalian cells by using recombinant adenovirus expressing site-specific Cre recombinase. Nucleic Acids Res (1995) 2.79
The rodent estrous cycle: characterization of vaginal cytology and its utility in toxicological studies. Birth Defects Res B Dev Reprod Toxicol (2007) 2.60
Mutations in the genes for oocyte-derived growth factors GDF9 and BMP15 are associated with both increased ovulation rate and sterility in Cambridge and Belclare sheep (Ovis aries). Biol Reprod (2003) 2.14
Methods for quantifying follicular numbers within the mouse ovary. Reproduction (2004) 1.89
Identification of new variants of human BMP15 gene in a large cohort of women with premature ovarian failure. J Clin Endocrinol Metab (2006) 1.81
The bone morphogenetic protein 15 gene is X-linked and expressed in oocytes. Mol Endocrinol (1998) 1.72
Hypergonadotropic ovarian failure associated with an inherited mutation of human bone morphogenetic protein-15 (BMP15) gene. Am J Hum Genet (2004) 1.72
Bone morphogenetic protein-15. Identification of target cells and biological functions. J Biol Chem (2000) 1.66
Oocyte-derived BMP15 and FGFs cooperate to promote glycolysis in cumulus cells. Development (2007) 1.50
Bone morphogenetic protein-15 inhibits follicle-stimulating hormone (FSH) action by suppressing FSH receptor expression. J Biol Chem (2001) 1.41
Molecular basis of bone morphogenetic protein-15 signaling in granulosa cells. J Biol Chem (2002) 1.38
Mutations and sequence variants in GDF9 and BMP15 in patients with premature ovarian failure. Eur J Endocrinol (2006) 1.36
A negative feedback system between oocyte bone morphogenetic protein 15 and granulosa cell kit ligand: its role in regulating granulosa cell mitosis. Proc Natl Acad Sci U S A (2002) 1.35
Ectopically expressed PDX-1 in liver initiates endocrine and exocrine pancreas differentiation but causes dysmorphogenesis. Biochem Biophys Res Commun (2003) 1.27
Missense mutations in the BMP15 gene are associated with ovarian failure. Hum Genet (2006) 1.27
Posttranslational processing of mouse and human BMP-15: potential implication in the determination of ovulation quota. Proc Natl Acad Sci U S A (2005) 1.14
Are BMP-15 and GDF-9 primary determinants of ovulation quota in mammals? Trends Endocrinol Metab (2004) 1.14
A unique preovulatory expression pattern plays a key role in the physiological functions of BMP-15 in the mouse. Proc Natl Acad Sci U S A (2006) 1.07
Senile changes in the oestrous cycle and in ovarian structure in some inbred strains of mice. Acta Endocrinol (Copenh) (1956) 1.01
Mutational analysis of BMP15 and GDF9 as candidate genes for premature ovarian failure. Fertil Steril (2006) 0.99
Essential role of the oocyte in estrogen amplification of follicle-stimulating hormone signaling in granulosa cells. Endocrinology (2005) 0.98
BMP15 mutations in XX gonadal dysgenesis and premature ovarian failure. Am J Obstet Gynecol (2007) 0.94
Oocyte bone morphogenetic protein 15, but not growth differentiation factor 9, is increased during gonadotropin-induced follicular development in the immature mouse and is associated with cumulus oophorus expansion. Biol Reprod (2006) 0.89
Sequence variants in exons of the BMP-15 gene in Chinese patients with premature ovarian failure. Acta Obstet Gynecol Scand (2007) 0.84
Counting cells made easier. Histopathology (2006) 0.83
Genetic mutations influencing ovulation rate in sheep. Reprod Fertil Dev (2001) 0.82
Pregnancy-associated plasma protein-a production in rat granulosa cells: stimulation by follicle-stimulating hormone and inhibition by the oocyte-derived bone morphogenetic protein-15. Endocrinology (2004) 0.80
Activin causes premature superovulation. Endocrinology (1995) 0.78
Evidence for widespread atresia in the hypophysectomized estrogen-treated rat. Endocrinology (1987) 0.78
Loss-of-function mutation in the prokineticin 2 gene causes Kallmann syndrome and normosmic idiopathic hypogonadotropic hypogonadism. Proc Natl Acad Sci U S A (2007) 2.23
Molecular diagnosis of human enteroviruses by phylogeny-based classification by use of the VP4 sequence. J Infect Dis (2002) 2.07
Transgenic expression of a myostatin inhibitor derived from follistatin increases skeletal muscle mass and ameliorates dystrophic pathology in mdx mice. FASEB J (2007) 1.65
A unique case of combined pituitary hormone deficiency caused by a PROP1 gene mutation (R120C) associated with normal height and absent puberty. Clin Endocrinol (Oxf) (2002) 1.54
GnRH activates ERK1/2 leading to the induction of c-fos and LHbeta protein expression in LbetaT2 cells. Mol Endocrinol (2002) 1.53
A novel AP-1 site is critical for maximal induction of the follicle-stimulating hormone beta gene by gonadotropin-releasing hormone. J Biol Chem (2003) 1.53
Oocyte-derived BMP15 and FGFs cooperate to promote glycolysis in cumulus cells. Development (2007) 1.50
Molecular basis of bone morphogenetic protein-15 signaling in granulosa cells. J Biol Chem (2002) 1.38
A negative feedback system between oocyte bone morphogenetic protein 15 and granulosa cell kit ligand: its role in regulating granulosa cell mitosis. Proc Natl Acad Sci U S A (2002) 1.35
Pulse sensitivity of the luteinizing hormone beta promoter is determined by a negative feedback loop Involving early growth response-1 and Ngfi-A binding protein 1 and 2. Mol Endocrinol (2007) 1.30
Involvement of both G(q/11) and G(s) proteins in gonadotropin-releasing hormone receptor-mediated signaling in L beta T2 cells. J Biol Chem (2002) 1.30
Circadian gene expression regulates pulsatile gonadotropin-releasing hormone (GnRH) secretory patterns in the hypothalamic GnRH-secreting GT1-7 cell line. J Neurosci (2003) 1.30
Integral role of GDF-9 and BMP-15 in ovarian function. Mol Reprod Dev (2011) 1.26
Hormones in synergy: regulation of the pituitary gonadotropin genes. Mol Cell Endocrinol (2009) 1.25
Activin regulation of the follicle-stimulating hormone beta-subunit gene involves Smads and the TALE homeodomain proteins Pbx1 and Prep1. Mol Endocrinol (2004) 1.22
Significance and therapeutic potential of endothelial progenitor cell transplantation in a cirrhotic liver rat model. Gastroenterology (2007) 1.22
Aberrant expression of growth differentiation factor-9 in oocytes of women with polycystic ovary syndrome. J Clin Endocrinol Metab (2002) 1.21
The spatiotemporal expression pattern of the bone morphogenetic protein family in rat ovary cell types during the estrous cycle. Reprod Biol Endocrinol (2003) 1.18
Activin isoforms signal through type I receptor serine/threonine kinase ALK7. Mol Cell Endocrinol (2004) 1.17
A novel function of bone morphogenetic protein-15 in the pituitary: selective synthesis and secretion of FSH by gonadotropes. Endocrinology (2002) 1.17
Developmental regulation of gonadotropin-releasing hormone gene expression by the MSX and DLX homeodomain protein families. J Biol Chem (2005) 1.17
Estrogenic activity of herbs commonly used as remedies for menopausal symptoms. Menopause (2002) 1.15
Posttranslational processing of mouse and human BMP-15: potential implication in the determination of ovulation quota. Proc Natl Acad Sci U S A (2005) 1.14
Are BMP-15 and GDF-9 primary determinants of ovulation quota in mammals? Trends Endocrinol Metab (2004) 1.14
p38 mitogen-activated protein kinase is critical for synergistic induction of the FSH(beta) gene by gonadotropin-releasing hormone and activin through augmentation of c-Fos induction and Smad phosphorylation. Mol Endocrinol (2007) 1.13
Androgens, progestins, and glucocorticoids induce follicle-stimulating hormone beta-subunit gene expression at the level of the gonadotrope. Mol Endocrinol (2006) 1.10
Transcriptional activation of the ovine follicle-stimulating hormone-beta gene by gonadotropin-releasing hormone involves multiple signal transduction pathways. Endocrinology (2002) 1.09
Activin regulates luteinizing hormone beta-subunit gene expression through Smad-binding and homeobox elements. Mol Endocrinol (2005) 1.08
Adiponectin activates adenosine monophosphate-activated protein kinase and decreases luteinizing hormone secretion in LbetaT2 gonadotropes. Mol Endocrinol (2007) 1.08
A unique preovulatory expression pattern plays a key role in the physiological functions of BMP-15 in the mouse. Proc Natl Acad Sci U S A (2006) 1.07
Necdin, a Prader-Willi syndrome candidate gene, regulates gonadotropin-releasing hormone neurons during development. Hum Mol Genet (2008) 1.07
Overexpression of angiopoietin-1 and angiopoietin-2 in hepatocellular carcinoma. J Hepatol (2004) 1.07
An Otx-related homeodomain protein binds an LHbeta promoter element important for activation during gonadotrope maturation. Mol Endocrinol (2002) 1.06
The Groucho-related gene family regulates the gonadotropin-releasing hormone gene through interaction with the homeodomain proteins MSX1 and OCT1. J Biol Chem (2005) 1.06
Increased androgen response to follicle-stimulating hormone administration in women with polycystic ovary syndrome. J Clin Endocrinol Metab (2008) 1.05
Phylogenetic footprinting reveals evolutionarily conserved regions of the gonadotropin-releasing hormone gene that enhance cell-specific expression. Mol Endocrinol (2004) 1.04
Hypothalamic dysregulation and infertility in mice lacking the homeodomain protein Six6. J Neurosci (2011) 1.04
TALE homeodomain proteins regulate gonadotropin-releasing hormone gene expression independently and via interactions with Oct-1. J Biol Chem (2004) 1.04
FoxL2 Is required for activin induction of the mouse and human follicle-stimulating hormone beta-subunit genes. Mol Endocrinol (2010) 1.03
Activin modulates the transcriptional response of LbetaT2 cells to gonadotropin-releasing hormone and alters cellular proliferation. Mol Endocrinol (2006) 1.02
Neuron-restricted expression of the rat gonadotropin-releasing hormone gene is conferred by a cell-specific protein complex that binds repeated CAATT elements. Mol Endocrinol (2002) 1.02
Mouse GnRH receptor gene expression is mediated by the LHX3 homeodomain protein. Endocrinology (2005) 1.02
Functional and molecular characterization of naturally occurring mutations in the oocyte-secreted factors bone morphogenetic protein-15 and growth and differentiation factor-9. J Biol Chem (2004) 1.02
Nuclear factor Y and steroidogenic factor 1 physically and functionally interact to contribute to cell-specific expression of the mouse Follicle-stimulating hormone-beta gene. Mol Endocrinol (2003) 1.01
Activin and glucocorticoids synergistically activate follicle-stimulating hormone beta-subunit gene expression in the immortalized LbetaT2 gonadotrope cell line. Endocrinology (2006) 1.01
GnRH induces the c-Fos gene via phosphorylation of SRF by the calcium/calmodulin kinase II pathway. Mol Endocrinol (2011) 1.00
Neuron-specific expression in vivo by defined transcription regulatory elements of the GnRH gene. Endocrinology (2002) 0.98
Essential role of the oocyte in estrogen amplification of follicle-stimulating hormone signaling in granulosa cells. Endocrinology (2005) 0.98
Structural and biophysical coupling of heparin and activin binding to follistatin isoform functions. J Biol Chem (2007) 0.97
Molecular epidemiology of norovirus gastroenteritis in Soma, Japan, 2001-2003. Pediatr Int (2008) 0.96
Effects of bone morphogenetic protein-7 (BMP-7) on primordial follicular growth in the mouse ovary. Mol Reprod Dev (2004) 0.95
Androgen regulates follicle-stimulating hormone beta gene expression in an activin-dependent manner in immortalized gonadotropes. Mol Endocrinol (2003) 0.95
Risk group stratification based on preoperative factors to predict survival after nephroureterectomy in patients with upper urinary tract urothelial carcinoma. Ann Surg Oncol (2013) 0.93
Otx2 induction of the gonadotropin-releasing hormone promoter is modulated by direct interactions with Grg co-repressors. J Biol Chem (2009) 0.93
Synergistic induction of follicle-stimulating hormone beta-subunit gene expression by gonadal steroid hormone receptors and Smad proteins. Endocrinology (2007) 0.93
Follicle-stimulating hormone regulates oocyte growth by modulation of expression of oocyte and granulosa cell factors. Endocrinology (2004) 0.93
Different signaling pathways control acute induction versus long-term repression of LHbeta transcription by GnRH. Endocrinology (2002) 0.93
Enhancers of GnRH transcription embedded in an upstream gene use homeodomain proteins to specify hypothalamic expression. Mol Endocrinol (2010) 0.92
Molecular biology and physiological role of the oocyte factor, BMP-15. Mol Cell Endocrinol (2005) 0.91
Phosphorylation of bone morphogenetic protein-15 and growth and differentiation factor-9 plays a critical role in determining agonistic or antagonistic functions. Endocrinology (2007) 0.89
Production and release of infectious hepatitis C virus from human liver cell cultures in the three-dimensional radial-flow bioreactor. Virology (2003) 0.89
A FoxL in the Smad house: activin regulation of FSH. Trends Endocrinol Metab (2010) 0.89
Vandetanib, an inhibitor of VEGF receptor-2 and EGF receptor, suppresses tumor development and improves prognosis of liver cancer in mice. Clin Cancer Res (2012) 0.88
FOXL2 is involved in the synergy between activin and progestins on the follicle-stimulating hormone β-subunit promoter. Endocrinology (2012) 0.88
Golgi apparatus casein kinase phosphorylates bioactive Ser-6 of bone morphogenetic protein 15 and growth and differentiation factor 9. FEBS Lett (2010) 0.88
Progesterone Inhibits basal and gonadotropin-releasing hormone induction of luteinizing hormone beta-subunit gene expression. Endocrinology (2008) 0.88
Suppression of transforming growth factor-beta results in upregulation of transcription of regeneration factors after chronic liver injury. J Hepatol (2004) 0.87
Characterization of the post-translational modification of recombinant human BMP-15 mature protein. Protein Sci (2008) 0.87
Aberrant development of the suprachiasmatic nucleus and circadian rhythms in mice lacking the homeodomain protein Six6. J Biol Rhythms (2013) 0.87
Prenatal exposure to low levels of androgen accelerates female puberty onset and reproductive senescence in mice. Endocrinology (2012) 0.85
Characterization of follistatin-related gene as a negative regulatory factor for activin family members during mouse heart development. J Med Invest (2007) 0.85
Interaction of endothelial progenitor cells expressing cytosine deaminase in tumor tissues and 5-fluorocytosine administration suppresses growth of 5-fluorouracil-sensitive liver cancer in mice. Cancer Sci (2012) 0.85
Diet-induced changes in Ucp1 expression in bovine adipose tissues. Gen Comp Endocrinol (2013) 0.85
NeuroD1 and Mash1 temporally regulate GnRH receptor gene expression in immortalized mouse gonadotrope cells. Mol Cell Endocrinol (2008) 0.84
KISS1R signals independently of Gαq/11 and triggers LH secretion via the β-arrestin pathway in the male mouse. Endocrinology (2014) 0.84
Bone morphogenetic protein-15 in the zebrafish ovary: complementary deoxyribonucleic acid cloning, genomic organization, tissue distribution, and role in oocyte maturation. Endocrinology (2005) 0.84
Heterozygous deletion of ventral anterior homeobox (vax1) causes subfertility in mice. Endocrinology (2014) 0.84
Compartment syndrome of bilateral lower extremities following laparoscopic surgery of rectal cancer in lithotomy position: report of a case. Surg Today (2006) 0.84
Runt-related transcription factors impair activin induction of the follicle-stimulating hormone {beta}-subunit gene. Endocrinology (2010) 0.83
PPARG regulates gonadotropin-releasing hormone signaling in LbetaT2 cells in vitro and pituitary gonadotroph function in vivo in mice. Biol Reprod (2010) 0.83
Pituitary tumorigenesis targeted by the ovine follicle-stimulating hormone beta-subunit gene regulatory region in transgenic mice. Mol Cell Endocrinol (2003) 0.83
The protein kinase C pathway acts through multiple transcription factors to repress gonadotropin-releasing hormone gene expression in hypothalamic GT1-7 neuronal cells. Mol Endocrinol (2005) 0.83
Correlation of postoperative recurrence in hepatocellular carcinoma with demethylation of repetitive sequences. Oncogene (2002) 0.83
Transplantation of endothelial progenitor cells ameliorates vascular dysfunction and portal hypertension in carbon tetrachloride-induced rat liver cirrhotic model. J Gastroenterol Hepatol (2013) 0.83
Impaired production of BMP-15 and GDF-9 mature proteins derived from proproteins WITH mutations in the proregion. Mol Cell Endocrinol (2010) 0.83
Gene dosage of Otx2 is important for fertility in male mice. Mol Cell Endocrinol (2013) 0.82
Orexin A induces GnRH gene expression and secretion from GT1-7 hypothalamic GnRH neurons. Neuroendocrinology (2006) 0.82
Dynamic chromatin modifications control GnRH gene expression during neuronal differentiation and protein kinase C signal transduction. Mol Endocrinol (2011) 0.82
Metronomic S-1 chemotherapy and vandetanib: an efficacious and nontoxic treatment for hepatocellular carcinoma. Neoplasia (2011) 0.82
Follistatin gene expression by gonadotropin-releasing hormone: a role for cyclic AMP and mitogen-activated protein kinase signaling pathways in clonal gonadotroph LbetaT2 cells. Mol Cell Endocrinol (2009) 0.81
Stress levels of glucocorticoids inhibit LHβ-subunit gene expression in gonadotrope cells. Mol Endocrinol (2012) 0.81
Expression of activin receptor-like kinase 7 in adipose tissues. Biochem Genet (2012) 0.80
Androgen receptor repression of GnRH gene transcription. Mol Endocrinol (2011) 0.80
Msx1 homeodomain protein represses the αGSU and GnRH receptor genes during gonadotrope development. Mol Endocrinol (2013) 0.80
Pregnancy-associated plasma protein-a production in rat granulosa cells: stimulation by follicle-stimulating hormone and inhibition by the oocyte-derived bone morphogenetic protein-15. Endocrinology (2004) 0.80
Glucocorticoids induce human glycoprotein hormone alpha-subunit gene expression in the gonadotrope. Endocrinology (2008) 0.80
Gene transfer of kringle 1-5 suppresses tumor development and improves prognosis of mice with hepatocellular carcinoma. Gastroenterology (2006) 0.79
Numerical study on an equivalent source model for inhomogeneous magnetic field dosimetry in the low-frequency range. IEEE Trans Biomed Eng (2004) 0.79