Published in Am J Psychiatry on April 01, 2008
European clinical guidelines for Tourette syndrome and other tic disorders. Part II: pharmacological treatment. Eur Child Adolesc Psychiatry (2011) 1.86
The 'atypicality' of antipsychotics: a concept re-examined and re-defined. Nat Rev Drug Discov (2009) 1.12
Evaluation of dopamine D₂/₃ specific binding in the cerebellum for the positron emission tomography radiotracer [¹¹C]FLB 457: implications for measuring cortical dopamine release. Synapse (2011) 0.90
Update on the Mechanism of Action of Aripiprazole: Translational Insights into Antipsychotic Strategies Beyond Dopamine Receptor Antagonism. CNS Drugs (2015) 0.90
Striatal and extrastriatal dopamine D₂ receptor occupancy by the partial agonist antipsychotic drug aripiprazole in the human brain: a positron emission tomography study with [¹¹C]raclopride and [¹¹C]FLB457. Psychopharmacology (Berl) (2012) 0.88
Population pharmacokinetic modelling of aripiprazole and its active metabolite, dehydroaripiprazole, in psychiatric patients. Br J Clin Pharmacol (2008) 0.84
Predicting brain occupancy from plasma levels using PET: superiority of combining pharmacokinetics with pharmacodynamics while modeling the relationship. J Cereb Blood Flow Metab (2011) 0.84
Efficacy and safety of aripiprazole in the treatment of bipolar disorder: a systematic review. Ann Gen Psychiatry (2009) 0.83
Understanding the hysteresis loop conundrum in pharmacokinetic/pharmacodynamic relationships. J Pharm Pharm Sci (2014) 0.82
Oculogyric crisis: a rare extrapyramidal side effect in the treatment of Tourette syndrome. Eur Child Adolesc Psychiatry (2012) 0.81
Effects of dopamine D2 receptor partial agonist antipsychotic aripiprazole on dopamine synthesis in human brain measured by PET with L-[β-11C]DOPA. PLoS One (2012) 0.80
Effects of repeated and acute aripiprazole or haloperidol treatment on dopamine synthesis in the dorsal striatum of young rats: comparison to adult rats. J Neural Transm (Vienna) (2010) 0.79
Antipsychotic dosing: found in translation. J Psychiatry Neurosci (2014) 0.79
An intercalation mechanism as a mode of action exerted by psychotropic drugs: results of altered phospholipid substrate availabilities in membranes? J Chem Biol (2010) 0.78
Aripiprazole in the treatment of challenging behaviour in adults with autism spectrum disorder. Psychopharmacology (Berl) (2012) 0.77
"There is no dose-response relationship in psychopharmacotherapy" vs "pharmacotherapy in psychiatry is based on ligand-receptor interaction": a unifying hypothesis and the need for plasma concentration based clinical trials. Psychopharmacology (Berl) (2011) 0.76
Adverse Effects and Toxicity of the Atypical Antipsychotics: What is Important for the Pediatric Emergency Medicine Practitioner. Clin Pediatr Emerg Med (2012) 0.76
Calculating occupancy when one does not have baseline: a comparison of different options. J Cereb Blood Flow Metab (2011) 0.75
New insights into clinical response in schizophrenia: from dopamine D2 receptor occupancy to patients' quality of life. Am J Psychiatry (2008) 0.75
Dopamine D₂/₃ occupancy of ziprasidone across a day: a within-subject PET study. Psychopharmacology (Berl) (2013) 0.75
Effects of antipsychotic treatment on psychopathology and motor symptoms. A placebo-controlled study in healthy volunteers. Psychopharmacology (Berl) (2011) 0.75
Correlation between dopamine D(2) receptors in the ventral striatum and central processing of alcohol cues and craving. Am J Psychiatry (2004) 2.84
Processing of generator-produced 68Ga for medical application. J Nucl Med (2007) 2.75
A disintegrin-metalloproteinase prevents amyloid plaque formation and hippocampal defects in an Alzheimer disease mouse model. J Clin Invest (2004) 2.52
Neural signatures of body ownership: a sensory network for bodily self-consciousness. Cereb Cortex (2006) 2.51
Chronic social stress inhibits cell proliferation in the adult medial prefrontal cortex: hemispheric asymmetry and reversal by fluoxetine treatment. Neuropsychopharmacology (2006) 1.72
Astroglial plasticity in the hippocampus is affected by chronic psychosocial stress and concomitant fluoxetine treatment. Neuropsychopharmacology (2005) 1.65
Association of low striatal dopamine d2 receptor availability with nicotine dependence similar to that seen with other drugs of abuse. Am J Psychiatry (2008) 1.53
Correlation of alcohol craving with striatal dopamine synthesis capacity and D2/3 receptor availability: a combined [18F]DOPA and [18F]DMFP PET study in detoxified alcoholic patients. Am J Psychiatry (2005) 1.41
68Ga-DOTATOC versus 68Ga-DOTATATE PET/CT in functional imaging of neuroendocrine tumors. J Nucl Med (2011) 1.27
Vascular imaging of solid tumors in rats with a radioactive arsenic-labeled antibody that binds exposed phosphatidylserine. Clin Cancer Res (2008) 1.23
High opiate receptor binding potential in the human lateral pain system. Neuroimage (2005) 1.20
Motion artifact reduction on parametric PET images of neuroreceptor binding. J Nucl Med (2005) 1.16
Impact of polymorphisms of cytochrome-P450 isoenzymes 2C9, 2C19 and 2D6 on plasma concentrations and clinical effects of antidepressants in a naturalistic clinical setting. Eur J Clin Pharmacol (2004) 1.16
In vivo imaging of adenosine A1 receptors in the human brain with [18F]CPFPX and positron emission tomography. Neuroimage (2003) 1.15
Parametric mapping of binding in human brain of D2 receptor ligands of different affinities. J Nucl Med (2005) 1.15
Pharmacological validation of a chronic social stress model of depression in rats: effects of reboxetine, haloperidol and diazepam. Behav Pharmacol (2008) 1.14
Net influx of plasma 6-[18F]fluoro-L-DOPA (FDOPA) to the ventral striatum correlates with prefrontal processing of affective stimuli. Eur J Neurosci (2006) 1.10
Pregabalin abuse and dependence in Germany: results from a database query. Eur J Clin Pharmacol (2013) 1.09
Desomorphine goes "crocodile". J Addict Dis (2012) 1.08
Citalopram counteracts depressive-like symptoms evoked by chronic social stress in rats. Behav Pharmacol (2006) 1.04
Cardiac resynchronization therapy homogenizes myocardial glucose metabolism and perfusion in dilated cardiomyopathy and left bundle branch block. J Am Coll Cardiol (2003) 1.04
Asymmetry in dopamine D(2/3) receptors of caudate nucleus is lost with age. Neuroimage (2006) 1.04
Effects of fluoxetine on behavioral deficits evoked by chronic social stress in rats. Behav Brain Res (2006) 1.03
Elevated [18F]fluorodopamine turnover in brain of patients with schizophrenia: an [18F]fluorodopa/positron emission tomography study. J Neurosci (2007) 1.02
Age-dependent decline of steady state dopamine storage capacity of human brain: an FDOPA PET study. Neurobiol Aging (2008) 1.00
Early reactions of brain-derived neurotrophic factor in plasma (pBDNF) and outcome to acute antidepressant treatment in patients with Major Depression. Neuropharmacology (2011) 1.00
The early non-increase of serum BDNF predicts failure of antidepressant treatment in patients with major depression: a pilot study. Prog Neuropsychopharmacol Biol Psychiatry (2010) 0.98
PET/CT imaging of osteoblastic bone metastases with (68)Ga-bisphosphonates: first human study. Eur J Nucl Med Mol Imaging (2010) 0.96
A triazacyclononane-based bifunctional phosphinate ligand for the preparation of multimeric 68Ga tracers for positron emission tomography. Chemistry (2010) 0.95
Indium-111 oxine labelling affects the cellular integrity of haematopoietic progenitor cells. Eur J Nucl Med Mol Imaging (2006) 0.95
Validation of 4D-MSPECT and QGS for quantification of left ventricular volumes and ejection fraction from gated 99mTc-MIBI SPET: comparison with cardiac magnetic resonance imaging. Eur J Nucl Med Mol Imaging (2004) 0.94
The quantification of dynamic FET PET imaging and correlation with the clinical outcome in patients with glioblastoma. Phys Med Biol (2009) 0.94
Subchronic haloperidol downregulates dopamine synthesis capacity in the brain of schizophrenic patients in vivo. Neuropsychopharmacology (2002) 0.94
The striatal and extrastriatal D2/D3 receptor-binding profile of clozapine in patients with schizophrenia. Neuropsychopharmacology (2006) 0.93
Effect of chronic citalopram on serotonin-related and stress-regulated genes in the dorsal raphe nucleus of the rat. Eur Neuropsychopharmacol (2006) 0.93
Quantification of D2-like dopamine receptors in the human brain with 18F-desmethoxyfallypride. J Nucl Med (2003) 0.93
Inhibition of O6-methylguanine-DNA methyltransferase by glucose-conjugated inhibitors: comparison with nonconjugated inhibitors and effect on fotemustine and temozolomide-induced cell death. J Pharmacol Exp Ther (2004) 0.93
Free-choice ethanol consumption under the influence of GABAergic drugs in rats. Alcohol Clin Exp Res (2002) 0.93
Enhancement of human cortico-motoneuronal excitability by the selective norepinephrine reuptake inhibitor reboxetine. Neurosci Lett (2002) 0.92
Effect of catheter-based transendocardial delivery of stromal cell-derived factor 1alpha on left ventricular function and perfusion in a porcine model of myocardial infarction. Basic Res Cardiol (2006) 0.92
In vivo evidence of deep brain stimulation-induced dopaminergic modulation in Tourette's syndrome. Biol Psychiatry (2011) 0.92
Comparison of FDG-PET/CT and bone scintigraphy for detection of bone metastases in breast cancer. Acta Radiol (2011) 0.92
Bithalamical deep brain stimulation in tourette syndrome is associated with reduction in dopaminergic transmission. Biol Psychiatry (2009) 0.90
Over-expression of two different forms of the alpha-secretase ADAM10 affects learning and memory in mice. Behav Brain Res (2006) 0.90
Synthesis and in vitro evaluation of (S)-2-([11C]methoxy)-4-[3-methyl-1-(2-piperidine-1-yl-phenyl)-butyl-carbamoyl]-benzoic acid ([11C]methoxy-repaglinide): a potential beta-cell imaging agent. Bioorg Med Chem Lett (2004) 0.90
Identification of P-glycoprotein substrates and inhibitors among psychoactive compounds--implications for pharmacokinetics of selected substrates. J Pharm Pharmacol (2004) 0.90
72/74As-labeling of HPMA based polymers for long-term in vivo PET imaging. Bioorg Med Chem Lett (2010) 0.89
Chronic lithium salt treatment reduces CRE/CREB-directed gene transcription and reverses its upregulation by chronic psychosocial stress in transgenic reporter gene mice. Neuropsychopharmacology (2007) 0.89
Serum levels of aripiprazole and dehydroaripiprazole, clinical response and side effects. World J Biol Psychiatry (2008) 0.89
Chronic psychosocial stress and citalopram modulate the expression of the glial proteins GFAP and NDRG2 in the hippocampus. Psychopharmacology (Berl) (2012) 0.89
Response and long-term control of bone metastases after peptide receptor radionuclide therapy with (177)Lu-octreotate. J Nucl Med (2011) 0.89
The applicability of SRTM in [(18)F]fallypride PET investigations: impact of scan durations. J Cereb Blood Flow Metab (2011) 0.89
Quantification of left ventricular volumes and ejection fraction from gated 99mTc-MIBI SPECT: validation of an elastic surface model approach in comparison to cardiac magnetic resonance imaging, 4D-MSPECT and QGS. Eur J Nucl Med Mol Imaging (2007) 0.88
In vitro affinities of various halogenated benzamide derivatives as potential radioligands for non-invasive quantification of D(2)-like dopamine receptors. Bioorg Med Chem (2007) 0.88
Radioactive labeling of defined HPMA-based polymeric structures using [18F]FETos for in vivo imaging by positron emission tomography. Biomacromolecules (2009) 0.88
Tyrosine hydroxylase Val-81-Met polymorphism associated with early-onset alcoholism. Psychiatr Genet (2005) 0.87
Therapeutic monitoring of new antipsychotic drugs. Ther Drug Monit (2004) 0.87
Quantification of left ventricular volumes and ejection fraction from gated 99mTc-MIBI SPECT: MRI validation of the EXINI heart software package. Clin Physiol Funct Imaging (2008) 0.86
Hormonal influences on cardiovascular norepinephrine transporter responses in healthy women. Hypertension (2008) 0.86
The chronic psychosocial stress paradigm in male tree shrews: evaluation of a novel animal model for depressive disorders. Stress (2002) 0.86
Clinical improvement in a case of frontotemporal dementia under aripiprazole treatment corresponds to partial recovery of disturbed frontal glucose metabolism. World J Biol Psychiatry (2007) 0.86
Blood-brain barrier penetration of the enantiomers of venlafaxine and its metabolites in mice lacking P-glycoprotein. Eur Neuropsychopharmacol (2010) 0.86
Aripiprazole in the pharmacotherapy of Gilles de la Tourette syndrome in adult patients. World J Biol Psychiatry (2009) 0.85
Striatal and extrastriatal D2/D3-receptor-binding properties of ziprasidone: a positron emission tomography study with [18F]Fallypride and [11C]raclopride (D2/D3-receptor occupancy of ziprasidone). J Clin Psychopharmacol (2008) 0.85
PET studies of net blood-brain clearance of FDOPA to human brain: age-dependent decline of [18F]fluorodopamine storage capacity. J Cereb Blood Flow Metab (2005) 0.85
Decreased dopamine D2/D3-receptor binding in temporal lobe epilepsy: an [18F]fallypride PET study. Epilepsia (2006) 0.85
Pharmacodynamic consequences of P-glycoprotein-dependent pharmacokinetics of risperidone and haloperidol in mice. Behav Brain Res (2007) 0.85
Opiate-induced dopamine release is modulated by severity of alcohol dependence: an [(18)F]fallypride positron emission tomography study. Biol Psychiatry (2011) 0.84
Therapeutic monitoring of aripiprazole by HPLC with column-switching and spectrophotometric detection. Clin Chem (2005) 0.84
Appropriateness of therapeutic drug monitoring for antidepressants in routine psychiatric inpatient care. Ther Drug Monit (2006) 0.84
Differential effects of escitalopram on attention: a placebo-controlled, double-blind cross-over study. Psychopharmacology (Berl) (2009) 0.84
Serotonin syndrome as a result of fluoxetine in a patient with tramadol abuse: plasma level-correlated symptomatology. J Clin Psychopharmacol (2002) 0.84
Effects of cardiac resynchronization therapy on myocardial blood flow measured by oxygen-15 water positron emission tomography in idiopathic-dilated cardiomyopathy and left bundle branch block. Am J Cardiol (2004) 0.84
The AGNP-TDM Expert Group Consensus Guidelines: focus on therapeutic monitoring of antidepressants. Dialogues Clin Neurosci (2005) 0.84
Toxic clozapine serum levels during inflammatory reactions. J Clin Psychopharmacol (2009) 0.84
Gallium(III) complexes of NOTA-bis (phosphonate) conjugates as PET radiotracers for bone imaging. Contrast Media Mol Imaging (2014) 0.84
Electron- and positron-emitting radiolanthanides for therapy: aspects of dosimetry and production. J Nucl Med (2006) 0.83
High striatal occupancy of D2-like dopamine receptors by amisulpride in the brain of patients with schizophrenia. Int J Neuropsychopharmacol (2004) 0.83
Positron emission tomography study of regional cerebral metabolism during general anesthesia with xenon in humans. Anesthesiology (2006) 0.83
The Acid Sphingomyelinase Sequence Variant p.A487V Is Not Associated With Decreased Levels of Enzymatic Activity. JIMD Rep (2012) 0.83
Therapeutic drug monitoring for drugs used in the treatment of substance-related disorders: literature review using a therapeutic drug monitoring appropriateness rating scale. Ther Drug Monit (2011) 0.83