Published in Lab Invest on April 07, 2008
Mouse models of diabetic nephropathy. J Am Soc Nephrol (2009) 3.74
Structural profiling of endogenous S-nitrosocysteine residues reveals unique features that accommodate diverse mechanisms for protein S-nitrosylation. Proc Natl Acad Sci U S A (2010) 1.87
Inflammation in diabetic nephropathy. Mediators Inflamm (2012) 1.81
Nitric oxide regulates mitochondrial fatty acid metabolism through reversible protein S-nitrosylation. Sci Signal (2013) 1.45
eNOS deficiency predisposes podocytes to injury in diabetes. J Am Soc Nephrol (2012) 1.26
Mouse models of diabetic nephropathy. Curr Opin Nephrol Hypertens (2011) 1.24
Abnormalities in signaling pathways in diabetic nephropathy. Expert Rev Endocrinol Metab (2010) 1.19
Long-term administration of the histone deacetylase inhibitor vorinostat attenuates renal injury in experimental diabetes through an endothelial nitric oxide synthase-dependent mechanism. Am J Pathol (2011) 1.17
Improvement of endothelial nitric oxide synthase activity retards the progression of diabetic nephropathy in db/db mice. Kidney Int (2012) 1.12
Nitric oxide synthase derangements and hypertension in kidney disease. Curr Opin Nephrol Hypertens (2012) 1.11
Glomerular endothelial cell injury and damage precedes that of podocytes in adriamycin-induced nephropathy. PLoS One (2013) 1.10
The kallikrein-kinin system in health and in diseases of the kidney. Kidney Int (2009) 1.04
Endothelial PGC-1α mediates vascular dysfunction in diabetes. Cell Metab (2014) 1.02
Reduction in basal nitric oxide activity causes albuminuria. Diabetes (2011) 1.01
Meox2Cre-mediated disruption of CSF-1 leads to osteopetrosis and osteocyte defects. Bone (2011) 0.94
Role of blood pressure and the renin-angiotensin system in development of diabetic nephropathy (DN) in eNOS-/- db/db mice. Am J Physiol Renal Physiol (2011) 0.94
The kallikrein-kinin system in diabetic nephropathy. Kidney Int (2012) 0.90
Renal endothelial dysfunction in diabetic nephropathy. Cardiovasc Hematol Disord Drug Targets (2014) 0.90
New experimental models of diabetic nephropathy in mice models of type 2 diabetes: efforts to replicate human nephropathy. Exp Diabetes Res (2012) 0.89
Advances in murine models of diabetic nephropathy. J Diabetes Res (2013) 0.88
Role of endothelial nitric oxide synthase in diabetic nephropathy: lessons from diabetic eNOS knockout mice. J Diabetes Res (2014) 0.88
A meta-analysis of three polymorphisms in the endothelial nitric oxide synthase gene (NOS3) and their effect on the risk of diabetic nephropathy. Hum Genet (2010) 0.87
Associations between structural and functional changes to the kidney in diabetic humans and mice. Life Sci (2013) 0.82
An ethanolic extract of Lindera obtusiloba stems, YJP-14, improves endothelial dysfunction, metabolic parameters and physical performance in diabetic db/db mice. PLoS One (2013) 0.81
Reduced hepatic eNOS phosphorylation is associated with NAFLD and type 2 diabetes progression and is prevented by daily exercise in hyperphagic OLETF rats. J Appl Physiol (1985) (2014) 0.81
Nodular lesions and mesangiolysis in diabetic nephropathy. Clin Exp Nephrol (2012) 0.81
Enhancing eNOS activity with simultaneous inhibition of IKKβ restores vascular function in Ins2(Akita+/-) type-1 diabetic mice. Lab Invest (2015) 0.79
Chronic Hyperphosphatemia and Vascular Calcification Are Reduced by Stable Delivery of Soluble Klotho. J Am Soc Nephrol (2016) 0.78
Targeted overexpression of endothelial nitric oxide synthase in endothelial cells improves cerebrovascular reactivity in Ins2Akita-type-1 diabetic mice. J Cereb Blood Flow Metab (2015) 0.78
Deficiency of eNOS exacerbates early-stage NAFLD pathogenesis by changing the fat distribution. BMC Gastroenterol (2015) 0.77
Mapping murine diabetic kidney disease using chemical exchange saturation transfer MRI. Magn Reson Med (2015) 0.77
Novel functions of circulating Klotho. Bone (2016) 0.75
IL-8 and eNOS polymorphisms predict bevacizumab-based first line treatment outcomes in RAS mutant metastatic colorectal cancer patients. Oncotarget (2017) 0.75
Role of interferon alpha in endothelial dysfunction: insights into endothelial nitric oxide synthase-related mechanisms. Am J Med Sci (2014) 0.75
Role of the eNOS-NO system in regulating the antiproteinuric effects of VEGF receptor 2 inhibition in diabetes. Biomed Res Int (2013) 0.75
Early development of podocyte injury independently of hyperglycemia and elevations in arterial pressure in nondiabetic obese Dahl SS leptin receptor mutant rats. Am J Physiol Renal Physiol (2016) 0.75
Pioglitazone for diabetes prevention in impaired glucose tolerance. N Engl J Med (2011) 4.28
Classification of proliferative pulmonary lesions of the mouse: recommendations of the mouse models of human cancers consortium. Cancer Res (2004) 3.43
Elevated toll-like receptor 4 expression and signaling in muscle from insulin-resistant subjects. Diabetes (2008) 2.76
Effect of acute exercise on AMPK signaling in skeletal muscle of subjects with type 2 diabetes: a time-course and dose-response study. Diabetes (2007) 2.26
Phosphorylation of Akt (Ser473) is an excellent predictor of poor clinical outcome in prostate cancer. Cancer Res (2004) 2.15
Peripheral disruption of the Grb10 gene enhances insulin signaling and sensitivity in vivo. Mol Cell Biol (2007) 2.08
Glucose metabolism and energy homeostasis in mouse hearts overexpressing dominant negative alpha2 subunit of AMP-activated protein kinase. J Biol Chem (2003) 2.07
A role for AMP-activated protein kinase in diabetes-induced renal hypertrophy. Am J Physiol Renal Physiol (2006) 2.05
Mechanism of action of exenatide to reduce postprandial hyperglycemia in type 2 diabetes. Am J Physiol Endocrinol Metab (2008) 1.67
Determining risk of biochemical recurrence in prostate cancer by immunohistochemical detection of PTEN expression and Akt activation. Clin Cancer Res (2007) 1.66
Long-Term Pioglitazone Treatment for Patients With Nonalcoholic Steatohepatitis and Prediabetes or Type 2 Diabetes Mellitus: A Randomized Trial. Ann Intern Med (2016) 1.65
CCR5 deficiency is not protective in the early stages of atherogenesis in apoE knockout mice. Atherosclerosis (2003) 1.63
Improved peptide elution time prediction for reversed-phase liquid chromatography-MS by incorporating peptide sequence information. Anal Chem (2006) 1.59
NFkappaB activity and transcriptional responses in human breast adenocarcinoma cells after single and fractionated irradiation. Cancer Biol Ther (2009) 1.53
LMP2/LMP7 gene variant: a risk factor for intestinal Mycobacterium tuberculosis infection in the Chinese population. J Gastroenterol Hepatol (2011) 1.45
Genetic analysis of the promoter region of the GATA4 gene in patients with ventricular septal defects. Transl Res (2011) 1.45
Effects of tuberculosis, race, and human gene SLCO1B1 polymorphisms on rifampin concentrations. Antimicrob Agents Chemother (2010) 1.45
A BAC-based physical map of the chicken genome. Genome Res (2003) 1.43
Signal transduction pathways in androgen-dependent and -independent prostate cancer cell proliferation. Endocr Relat Cancer (2005) 1.43
Reduced skeletal muscle inhibitor of kappaB beta content is associated with insulin resistance in subjects with type 2 diabetes: reversal by exercise training. Diabetes (2006) 1.41
Osteoblastoma of the maxilla and mandible: a report of 24 cases, review of the literature, and discussion of its relationship to osteoid osteoma of the jaws. Oral Surg Oral Med Oral Pathol Oral Radiol Endod (2006) 1.41
Aberrant activation of AMP-activated protein kinase remodels metabolic network in favor of cardiac glycogen storage. J Clin Invest (2007) 1.40
MicroRNA-320a suppresses human colon cancer cell proliferation by directly targeting β-catenin. Biochem Biophys Res Commun (2012) 1.40
Quantitative and trajectory analysis of movement trajectories in supplementary motor area seizures of frontal lobe epilepsy. Epilepsy Behav (2008) 1.39
Does reduced IGF-1R signaling in Igf1r+/- mice alter aging? PLoS One (2011) 1.39
Collective dipole oscillations of a spin-orbit coupled Bose-Einstein condensate. Phys Rev Lett (2012) 1.37
Activation instead of blocking mesolimbic dopaminergic reward circuitry is a preferred modality in the long term treatment of reward deficiency syndrome (RDS): a commentary. Theor Biol Med Model (2008) 1.35
Physiological and molecular determinants of insulin action in the baboon. Diabetes (2008) 1.34
Live imaging reveals differing roles of macrophages and neutrophils during zebrafish tail fin regeneration. J Biol Chem (2012) 1.30
Evaluation of napsin A, cytokeratin 5/6, p63, and thyroid transcription factor 1 in adenocarcinoma versus squamous cell carcinoma of the lung. Arch Pathol Lab Med (2012) 1.30
Experimental arthritis in CC chemokine receptor 2-null mice closely mimics severe human rheumatoid arthritis. J Clin Invest (2004) 1.28
Whole body overexpression of PGC-1alpha has opposite effects on hepatic and muscle insulin sensitivity. Am J Physiol Endocrinol Metab (2009) 1.23
Pioglitazone slows progression of atherosclerosis in prediabetes independent of changes in cardiovascular risk factors. Arterioscler Thromb Vasc Biol (2012) 1.22
Stability of quantum dots in live cells. Nat Chem (2011) 1.22
A randomized single-blind pilot study of compensatory strategies in schizophrenia outpatients. Schizophr Bull (2002) 1.20
LKB1-AMPK signaling in muscle from obese insulin-resistant Zucker rats and effects of training. Am J Physiol Endocrinol Metab (2005) 1.20
Nuclear versus cytoplasmic localization of filamin A in prostate cancer: immunohistochemical correlation with metastases. Clin Cancer Res (2009) 1.20
Induction of adaptive response in human blood lymphocytes exposed to radiofrequency radiation. Radiat Res (2009) 1.18
Increased alpha2 subunit-associated AMPK activity and PRKAG2 cardiomyopathy. Circulation (2005) 1.18
Quantitative evaluation of protein-DNA interactions using an optimized knowledge-based potential. Nucleic Acids Res (2005) 1.18
Viral-associated trichodysplasia spinulosa: a case with electron microscopic and molecular detection of the trichodysplasia spinulosa-associated human polyomavirus. J Cutan Pathol (2011) 1.17
Graft-union development: a delicate process that involves cell-cell communication between scion and stock for local auxin accumulation. J Exp Bot (2012) 1.16
CC chemokine receptor 5 influences late-stage atherosclerosis. Atherosclerosis (2007) 1.16
Surface properties dictate uptake, distribution, excretion, and toxicity of nanoparticles in fish. Small (2010) 1.16
Colorimetric bacteria sensing using a supramolecular enzyme-nanoparticle biosensor. J Am Chem Soc (2011) 1.16
Step-wise specification of retinal stem cells during normal embryogenesis. Biol Cell (2005) 1.15
Actos Now for the prevention of diabetes (ACT NOW) study. BMC Endocr Disord (2009) 1.15
Structural genomics analysis of alternative splicing and application to isoform structure modeling. Proc Natl Acad Sci U S A (2005) 1.15
Attention-deficit-hyperactivity disorder and reward deficiency syndrome. Neuropsychiatr Dis Treat (2008) 1.14
Beyond AICA riboside: in search of new specific AMP-activated protein kinase activators. IUBMB Life (2009) 1.14
Spatial and seasonal trends in biogenic secondary organic aerosol tracers and water-soluble organic carbon in the southeastern United States. Environ Sci Technol (2008) 1.12
Eya1 and Six1 promote neurogenesis in the cranial placodes in a SoxB1-dependent fashion. Dev Biol (2008) 1.12
Palmitic acid induces IP-10 expression in human macrophages via NF-kappaB activation. Biochem Biophys Res Commun (2007) 1.12
Intra-organ variation in age-related mutation accumulation in the mouse. PLoS One (2007) 1.11
Aortic constriction exacerbates atherosclerosis and induces cardiac dysfunction in mice lacking apolipoprotein E. Arterioscler Thromb Vasc Biol (2002) 1.11
Evaluation of time to detection of Mycobacterium tuberculosis in broth culture as a determinant for end points in treatment trials. J Clin Microbiol (2010) 1.11
High glucose induced nuclear factor kappa B mediated inhibition of endothelial cell migration. Atherosclerosis (2002) 1.11
Development of a synthetic promoter for macrophage gene therapy. Hum Gene Ther (2006) 1.09
Pilot association study of oxcarbazepine-induced mild cutaneous adverse reactions with HLA-B*1502 allele in Chinese Han population. Seizure (2010) 1.08
Radiation-triggered tumor necrosis factor (TNF) alpha-NFkappaB cross-signaling favors survival advantage in human neuroblastoma cells. J Biol Chem (2011) 1.07
Fabrication of corona-free nanoparticles with tunable hydrophobicity. ACS Nano (2014) 1.07
How the relationship of attitudes toward mental health treatment and service use differs by age, gender, ethnicity/race and education. Soc Psychiatry Psychiatr Epidemiol (2009) 1.07
Reduction in reactive oxygen species production by mitochondria from elderly subjects with normal and impaired glucose tolerance. Diabetes (2011) 1.07
AMP-activated protein kinase: Role in metabolism and therapeutic implications. Diabetes Obes Metab (2006) 1.07
Peptide sequence tag-based blind identification of post-translational modifications with point process model. Bioinformatics (2006) 1.07
Fat-specific DsbA-L overexpression promotes adiponectin multimerization and protects mice from diet-induced obesity and insulin resistance. Diabetes (2012) 1.07
Exercise training decreases the concentration of malonyl-CoA and increases the expression and activity of malonyl-CoA decarboxylase in human muscle. Am J Physiol Endocrinol Metab (2006) 1.05
NF-κB activity in muscle from obese and type 2 diabetic subjects under basal and exercise-stimulated conditions. Am J Physiol Endocrinol Metab (2010) 1.05
Generation and characterization of a large panel of murine monoclonal antibodies against vaccinia virus. Virology (2010) 1.05
Efficacy of Mycobacterium indicus pranii immunotherapy as an adjunct to chemotherapy for tuberculosis and underlying immune responses in the lung. PLoS One (2012) 1.05
Potential use of drug carried-liposomes for cancer therapy via direct intratumoral injection. Int J Pharm (2006) 1.04
Positive margins following surgical resection of breast carcinoma: analysis of pathologic correlates. J Surg Oncol (2004) 1.02
Prediction of diabetes based on baseline metabolic characteristics in individuals at high risk. Diabetes Care (2013) 1.01
White matter impairment in the basal ganglia-thalamocortical circuit of drug-naïve childhood absence epilepsy. Epilepsy Res (2012) 1.01
Calibration of Silver Plasmon Rulers in the 1-25 nm Separation Range: Experimental Indications of Distinct Plasmon Coupling Regimes. J Phys Chem C Nanomater Interfaces (2010) 1.01
Effects of pioglitazone on intramyocellular fat metabolism in patients with type 2 diabetes mellitus. J Clin Endocrinol Metab (2010) 1.01
Effect of lipopolysaccharide on inflammation and insulin action in human muscle. PLoS One (2013) 0.99
Array-based sensing of metastatic cells and tissues using nanoparticle-fluorescent protein conjugates. ACS Nano (2012) 0.98
Induction of adaptive response in human blood lymphocytes exposed to 900 MHz radiofrequency fields: influence of cell cycle. Int J Radiat Biol (2011) 0.98
Setup and characterization of a human head and neck squamous cell carcinoma xenograft model in nude rats. Otolaryngol Head Neck Surg (2006) 0.98
Role of astrocytes and chemokine systems in acute TNFalpha induced demyelinating syndrome: CCR2-dependent signals promote astrocyte activation and survival via NF-kappaB and Akt. Mol Cell Neurosci (2007) 0.98
Regulation of glucose transport by the AMP-activated protein kinase. Proc Nutr Soc (2004) 0.98
Chemoradionuclide therapy with 186Re-labeled liposomal doxorubicin in combination with radiofrequency ablation for effective treatment of head and neck cancer in a nude rat tumor xenograft model. Radiology (2011) 0.98
Association study of lamotrigine-induced cutaneous adverse reactions and HLA-B*1502 in a Han Chinese population. Epilepsy Res (2010) 0.98
Prevention of diabetes with pioglitazone in ACT NOW: physiologic correlates. Diabetes (2013) 0.97
APPL1 mediates adiponectin-induced LKB1 cytosolic localization through the PP2A-PKCzeta signaling pathway. Mol Endocrinol (2011) 0.97
High glucose-induced IKK-Hsp-90 interaction contributes to endothelial dysfunction. Am J Physiol Cell Physiol (2008) 0.97
The ontogeny of insulin signaling in the preterm baboon model. Endocrinology (2010) 0.97
The site specific demethylation in the 5'-regulatory area of NMDA receptor 2B subunit gene associated with CIE-induced up-regulation of transcription. PLoS One (2010) 0.97
Covalent attaching protein to graphene oxide via diimide-activated amidation. Colloids Surf B Biointerfaces (2010) 0.97
Tribbles 3 mediates endoplasmic reticulum stress-induced insulin resistance in skeletal muscle. Nat Commun (2013) 0.97
TSA suppresses miR-106b-93-25 cluster expression through downregulation of MYC and inhibits proliferation and induces apoptosis in human EMC. PLoS One (2012) 0.96
Synthesis of cationic quantum dots via a two-step ligand exchange process. Chem Commun (Camb) (2011) 0.95
Few-layered CoHPO4 · 3H2O ultrathin nanosheets for high performance of electrode materials for supercapacitors. Nanoscale (2013) 0.95
Disruption of growth factor receptor-binding protein 10 in the pancreas enhances β-cell proliferation and protects mice from streptozotocin-induced β-cell apoptosis. Diabetes (2012) 0.95
Fenoldopam inhibits nuclear translocation of nuclear factor kappa B in a rat model of surgical ischemic acute renal failure. J Cardiothorac Vasc Anesth (2006) 0.95
Optical sizing of immunolabel clusters through multispectral plasmon coupling microscopy. Nano Lett (2011) 0.95
IKKbeta mediates cell shape-induced aromatase expression and estrogen biosynthesis in adipose stromal cells. Mol Endocrinol (2009) 0.95