Published in Bioorg Med Chem Lett on March 21, 2008
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Augmentation of neovascularization [corrected] in hindlimb ischemia by combined transplantation of human embryonic stem cells-derived endothelial and mural cells. PLoS One (2008) 1.36
Trichostatin A, a histone deacetylase inhibitor, suppresses collagen synthesis and prevents TGF-beta(1)-induced fibrogenesis in skin fibroblasts. Exp Cell Res (2002) 1.36
Identification of SAP155 as the target of GEX1A (Herboxidiene), an antitumor natural product. ACS Chem Biol (2011) 1.34
Induction and enhancement of cardiac cell differentiation from mouse and human induced pluripotent stem cells with cyclosporin-A. PLoS One (2011) 1.33
13-Deoxytedanolide, a marine sponge-derived antitumor macrolide, binds to the 60S large ribosomal subunit. Bioorg Med Chem (2005) 1.32
A role for PP1 in the Cdc2/Cyclin B-mediated positive feedback activation of Cdc25. Mol Biol Cell (2006) 1.31
Pluripotent stem cell-engineered cell sheets reassembled with defined cardiovascular populations ameliorate reduction in infarct heart function through cardiomyocyte-mediated neovascularization. Stem Cells (2012) 1.27
Enhanced HSP70 lysine methylation promotes proliferation of cancer cells through activation of Aurora kinase B. Nat Commun (2012) 1.27
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Structure-activity relationship for FR901464: a versatile method for the conversion and preparation of biologically active biotinylated probes. Biosci Biotechnol Biochem (2004) 1.23
Prognostic impact of immunohistochemical biomarkers in diffuse large B-cell lymphoma in the rituximab era. Cancer Sci (2009) 1.22
Design, synthesis, structure--selectivity relationship, and effect on human cancer cells of a novel series of histone deacetylase 6-selective inhibitors. J Med Chem (2007) 1.22
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Real-time imaging of histone H4 hyperacetylation in living cells. Proc Natl Acad Sci U S A (2009) 1.20
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Bach1 inhibits oxidative stress-induced cellular senescence by impeding p53 function on chromatin. Nat Struct Mol Biol (2008) 1.18
Hyperpolarization-activated cyclic nucleotide-gated channels and T-type calcium channels confer automaticity of embryonic stem cell-derived cardiomyocytes. Stem Cells (2007) 1.17
Leptomycin B, an inhibitor of the nuclear export receptor CRM1, inhibits COX-2 expression. J Biol Chem (2002) 1.15
Spliceosome assembly is coupled to RNA polymerase II dynamics at the 3' end of human genes. Nat Struct Mol Biol (2011) 1.15
HIV-1 Tat targets Tip60 to impair the apoptotic cell response to genotoxic stresses. EMBO J (2005) 1.14
Histone deacetylase inhibitor reduces monocyte adhesion to endothelium through the suppression of vascular cell adhesion molecule-1 expression. Arterioscler Thromb Vasc Biol (2006) 1.14
Enhancement of vascular progenitor potential by protein kinase A through dual induction of Flk-1 and Neuropilin-1. Blood (2009) 1.11
Proteasomes activate aggresome disassembly and clearance by producing unanchored ubiquitin chains. Mol Cell (2013) 1.10
Nucleocytoplasmic transport of fluorescent mRNA in living mammalian cells: nuclear mRNA export is coupled to ongoing gene transcription. Genes Cells (2006) 1.10
Co-repressor SMRT and class II histone deacetylases promote Bach2 nuclear retention and formation of nuclear foci that are responsible for local transcriptional repression. J Biochem (2007) 1.10
The first biologically active synthetic analogues of FK228, the depsipeptide histone deacetylase inhibitor. J Med Chem (2007) 1.09
Reactive oxygen species regulate DNA copy number in isolated yeast mitochondria by triggering recombination-mediated replication. Nucleic Acids Res (2008) 1.08
Multiple histone deacetylases and the CREB-binding protein regulate pre-mRNA 3'-end processing. J Biol Chem (2006) 1.08
Global analysis of gel mobility of proteins and its use in target identification. J Biol Chem (2008) 1.07
Azumamides A-E: histone deacetylase inhibitory cyclic tetrapeptides from the marine sponge Mycale izuensis. Angew Chem Int Ed Engl (2006) 1.07
Chromosomal region maintenance 1 (CRM1)-dependent nuclear export of Smad ubiquitin regulatory factor 1 (Smurf1) is essential for negative regulation of transforming growth factor-beta signaling by Smad7. J Biol Chem (2003) 1.05
Highly potent and selective histone deacetylase 6 inhibitors designed based on a small-molecular substrate. J Med Chem (2006) 1.04
Splicing in oncogenesis and tumor suppression. Cancer Sci (2012) 1.03
High level of endothelial cell-specific gene expression by a combination of the 5' flanking region and the 5' half of the first intron of the VE-cadherin gene. Blood (2005) 1.02
Protein kinase A determines timing of early differentiation through epigenetic regulation with G9a. Cell Stem Cell (2012) 1.02
PKA/CREB signaling triggers initiation of endothelial and hematopoietic cell differentiation via Etv2 induction. Stem Cells (2012) 1.01
Marine antifungal theonellamides target 3beta-hydroxysterol to activate Rho1 signaling. Nat Chem Biol (2010) 1.00
Regulation of E2A activities by histone acetyltransferases in B lymphocyte development. J Biol Chem (2002) 1.00
14-3-3 regulates the nuclear import of class IIa histone deacetylases. Biochem Biophys Res Commun (2008) 1.00
Spliceostatin A blocks angiogenesis by inhibiting global gene expression including VEGF. Cancer Sci (2010) 1.00
Gliotoxin analogues from a marine-derived fungus, Penicillium sp., and their cytotoxic and histone methyltransferase inhibitory activities. J Nat Prod (2011) 1.00
Cyclic strain induces mouse embryonic stem cell differentiation into vascular smooth muscle cells by activating PDGF receptor beta. J Appl Physiol (1985) (2008) 0.99
Repression of PML nuclear body-associated transcription by oxidative stress-activated Bach2. Mol Cell Biol (2004) 0.99
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The protein farnesyltransferase regulates HDAC6 activity in a microtubule-dependent manner. J Biol Chem (2009) 0.98
Cyclosporin-A potently induces highly cardiogenic progenitors from embryonic stem cells. Biochem Biophys Res Commun (2008) 0.98
Therapeutic angiogenesis by transplantation of induced pluripotent stem cell-derived Flk-1 positive cells. BMC Cell Biol (2010) 0.97
Inhibition of protein synthesis and activation of stress-activated protein kinases by onnamide A and theopederin B, antitumor marine natural products. Cancer Sci (2005) 0.96
Padanamides A and B, highly modified linear tetrapeptides produced in culture by a Streptomyces sp. isolated from a marine sediment. Org Lett (2011) 0.96
Nuclear-cytoplasmic shuttling of a RING-IBR protein RBCK1 and its functional interaction with nuclear body proteins. J Biol Chem (2005) 0.96
A comparative genomic approach for identifying synthetic lethal interactions in human cancer. Cancer Res (2013) 0.95
A novel oral neutrophil elastase inhibitor (ONO-6818) inhibits human neutrophil elastase-induced emphysema in rats. Am J Respir Crit Care Med (2002) 0.95