Published in Physiology (Bethesda) on April 01, 2008
The Concise Guide to PHARMACOLOGY 2013/14: transporters. Br J Pharmacol (2013) 2.07
Chloride channels: often enigmatic, rarely predictable. Annu Rev Physiol (2010) 1.94
Molecular mechanism of pancreatic and salivary gland fluid and HCO3 secretion. Physiol Rev (2012) 1.71
Analysis and update of the human solute carrier (SLC) gene superfamily. Hum Genomics (2009) 1.62
Structure of a prokaryotic fumarate transporter reveals the architecture of the SLC26 family. Nat Struct Mol Biol (2015) 1.59
Novel role for pendrin in orchestrating bicarbonate secretion in cystic fibrosis transmembrane conductance regulator (CFTR)-expressing airway serous cells. J Biol Chem (2011) 1.55
The divergence, actions, roles, and relatives of sodium-coupled bicarbonate transporters. Physiol Rev (2013) 1.50
The SLC26 gene family of anion transporters and channels. Mol Aspects Med (2013) 1.50
Modular structure of sodium-coupled bicarbonate transporters. J Exp Biol (2009) 1.46
SLC26A9 is a constitutively active, CFTR-regulated anion conductance in human bronchial epithelia. J Gen Physiol (2009) 1.44
The Slc26a4 transporter functions as an electroneutral Cl-/I-/HCO3- exchanger: role of Slc26a4 and Slc26a6 in I- and HCO3- secretion and in regulation of CFTR in the parotid duct. J Physiol (2008) 1.40
Diverse transport modes by the solute carrier 26 family of anion transporters. J Physiol (2008) 1.35
Chloride sensing by WNK1 involves inhibition of autophosphorylation. Sci Signal (2014) 1.33
IRBIT coordinates epithelial fluid and HCO3- secretion by stimulating the transporters pNBC1 and CFTR in the murine pancreatic duct. J Clin Invest (2008) 1.32
IRBIT governs epithelial secretion in mice by antagonizing the WNK/SPAK kinase pathway. J Clin Invest (2011) 1.18
Regulation of transport in the connecting tubule and cortical collecting duct. Compr Physiol (2012) 1.16
Physiology of epithelial chloride and fluid secretion. Cold Spring Harb Perspect Med (2012) 1.16
FGF signaling regulates otic placode induction and refinement by controlling both ectodermal target genes and hindbrain Wnt8a. Dev Biol (2010) 1.15
Bicarbonate transporters in corals point towards a key step in the evolution of cnidarian calcification. Sci Rep (2015) 1.10
The switch of intestinal Slc26 exchangers from anion absorptive to HCOFormula secretory mode is dependent on CFTR anion channel function. Am J Physiol Cell Physiol (2010) 1.08
Evidence that prestin has at least two voltage-dependent steps. J Biol Chem (2010) 1.05
Determinants of coupled transport and uncoupled current by the electrogenic SLC26 transporters. J Gen Physiol (2011) 1.05
STAS domain structure and function. Cell Physiol Biochem (2011) 1.00
Na-coupled bicarbonate transporters of the solute carrier 4 family in the nervous system: function, localization, and relevance to neurologic function. Neuroscience (2010) 0.98
Functional coupling of apical Cl-/HCO3- exchange with CFTR in stimulated HCO3- secretion by guinea pig interlobular pancreatic duct. Am J Physiol Gastrointest Liver Physiol (2009) 0.98
Acquisition of dietary copper: a role for anion transporters in intestinal apical copper uptake. Am J Physiol Cell Physiol (2010) 0.97
Solution structure of the guanine nucleotide-binding STAS domain of SLC26-related SulP protein Rv1739c from Mycobacterium tuberculosis. J Biol Chem (2010) 0.97
Regulated transport of sulfate and oxalate by SLC26A2/DTDST. Am J Physiol Cell Physiol (2010) 0.96
Molecular architecture and the structural basis for anion interaction in prestin and SLC26 transporters. Nat Commun (2014) 0.94
Ion transport in the intestine. Curr Opin Gastroenterol (2009) 0.93
Identification of uterine ion transporters for mineralisation precursors of the avian eggshell. BMC Physiol (2012) 0.93
Anion transport and GABA signaling. Front Cell Neurosci (2013) 0.91
Mammalian prestin is a weak Cl⁻/HCO₃⁻ electrogenic antiporter. J Physiol (2012) 0.91
Drosophila melanogaster as an emerging translational model of human nephrolithiasis. J Urol (2013) 0.91
Low resolution structure of a bacterial SLC26 transporter reveals dimeric stoichiometry and mobile intracellular domains. J Biol Chem (2011) 0.90
IRBIT: it is everywhere. Neurochem Res (2010) 0.88
Rescue of epithelial HCO3- secretion in murine intestine by apical membrane expression of the cystic fibrosis transmembrane conductance regulator mutant F508del. J Physiol (2012) 0.88
Solute carrier family 26 member a2 (Slc26a2) protein functions as an electroneutral SOFormula/OH-/Cl- exchanger regulated by extracellular Cl-. J Biol Chem (2011) 0.85
SLC26A6 and NaDC-1 transporters interact to regulate oxalate and citrate homeostasis. J Am Soc Nephrol (2013) 0.85
Transepithelial bicarbonate secretion: lessons from the pancreas. Cold Spring Harb Perspect Med (2012) 0.84
TMFoldRec: a statistical potential-based transmembrane protein fold recognition tool. BMC Bioinformatics (2015) 0.84
Ion and solute transport by Prestin in Drosophila and Anopheles. J Insect Physiol (2012) 0.83
Anion translocation through an Slc26 transporter mediates lumen expansion during tubulogenesis. Proc Natl Acad Sci U S A (2013) 0.83
Thyroid iodide efflux: a team effort? J Physiol (2011) 0.83
The cystic fibrosis of exocrine pancreas. Cold Spring Harb Perspect Med (2013) 0.83
The roles of conserved and nonconserved cysteinyl residues in the oligomerization and function of mammalian prestin. J Neurophysiol (2011) 0.82
Effects of chronic continuous hypoxia on the expression of SLC4A8 (NDCBE) in neonatal versus adult mouse brain. Brain Res (2008) 0.82
Ducts isolated from the pancreas of CFTR-null mice secrete fluid. Pflugers Arch (2009) 0.82
CFTR-SLC26 transporter interactions in epithelia. Biophys Rev (2012) 0.82
Mechanism and synergism in epithelial fluid and electrolyte secretion. Pflugers Arch (2013) 0.80
Role of AE2 for pHi regulation in biliary epithelial cells. Front Physiol (2014) 0.80
The properties, functions, and pathophysiology of maxi-anion channels. Pflugers Arch (2016) 0.79
The pendrin anion exchanger gene is transcriptionally regulated by uroguanylin: a novel enterorenal link. Am J Physiol Renal Physiol (2011) 0.78
Multiple roles of the SO4(2-)/Cl-/OH- exchanger protein Slc26a2 in chondrocyte functions. J Biol Chem (2013) 0.77
Functional analysis of nonsynonymous single nucleotide polymorphisms in human SLC26A9. Hum Mutat (2012) 0.77
Potassium channels in pancreatic duct epithelial cells: their role, function and pathophysiological relevance. Pflugers Arch (2014) 0.76
Primers on molecular pathways: bicarbonate transport by the pancreas. Pancreatology (2011) 0.76
Comprehensive transcriptomic analysis of Tibetan Schizothoracinae fish Gymnocypris przewalskii reveals how it adapts to a high altitude aquatic life. BMC Evol Biol (2017) 0.76
Generation of somatic electromechanical force by outer hair cells may be influenced by prestin-CASK interaction at the basal junction with the Deiter's cell. Histochem Cell Biol (2013) 0.76
Atrophic thyroid follicles and inner ear defects reminiscent of cochlear hypothyroidism in Slc26a4-related deafness. Mamm Genome (2014) 0.76
Ahcyl2 upregulates NBCe1-B via multiple serine residues of the PEST domain-mediated association. Korean J Physiol Pharmacol (2016) 0.76
The role of intestinal oxalate transport in hyperoxaluria and the formation of kidney stones in animals and man. Urolithiasis (2016) 0.76
Sparkling water--bicarbonate for cervix and cystic fibrosis. J Physiol (2010) 0.75
Function and expression of cystic fibrosis transmembrane conductance regulator after small intestinal transplantation in mice. PLoS One (2013) 0.75
Current carried by the Slc26 family member prestin does not flow through the transporter pathway. Sci Rep (2017) 0.75
Guanine nucleotides differentially modulate backbone dynamics of the STAS domain of the SulP/SLC26 transport protein Rv1739c of Mycobacterium tuberculosis. FEBS J (2011) 0.75
Human SLC26A4/Pendrin STAS domain is a nucleotide-binding protein: Refolding and characterization for structural studies. Biochem Biophys Rep (2016) 0.75
The CFTR trafficking mutation F508del inhibits the constitutive activity of SLC26A9. Am J Physiol Lung Cell Mol Physiol (2017) 0.75
STIM1 carboxyl-terminus activates native SOC, I(crac) and TRPC1 channels. Nat Cell Biol (2006) 5.68
SOAR and the polybasic STIM1 domains gate and regulate Orai channels. Nat Cell Biol (2009) 4.73
STIM1 heteromultimerizes TRPC channels to determine their function as store-operated channels. Nat Cell Biol (2007) 3.47
Gating of CFTR by the STAS domain of SLC26 transporters. Nat Cell Biol (2004) 3.43
Homer binds TRPC family channels and is required for gating of TRPC1 by IP3 receptors. Cell (2003) 3.11
STIM1 gates TRPC channels, but not Orai1, by electrostatic interaction. Mol Cell (2008) 2.30
A molecular mechanism for aberrant CFTR-dependent HCO(3)(-) transport in cystic fibrosis. EMBO J (2002) 2.11
TRPC channels as STIM1-regulated store-operated channels. Cell Calcium (2007) 2.04
NaBC1 is a ubiquitous electrogenic Na+ -coupled borate transporter essential for cellular boron homeostasis and cell growth and proliferation. Mol Cell (2004) 2.02
TRP-ML1 regulates lysosomal pH and acidic lysosomal lipid hydrolytic activity. J Biol Chem (2005) 1.96
Transporter-mediated bile acid uptake causes Ca2+-dependent cell death in rat pancreatic acinar cells. Gastroenterology (2002) 1.91
Corticosteroids correct aberrant CFTR localization in the duct and regenerate acinar cells in autoimmune pancreatitis. Gastroenterology (2010) 1.86
TRP-ML1 is a lysosomal monovalent cation channel that undergoes proteolytic cleavage. J Biol Chem (2005) 1.75
Coupling modes and stoichiometry of Cl-/HCO3- exchange by slc26a3 and slc26a6. J Gen Physiol (2006) 1.73
Protease-activated receptor 2 exerts local protection and mediates some systemic complications in acute pancreatitis. Gastroenterology (2004) 1.72
Molecular mechanism of pancreatic and salivary gland fluid and HCO3 secretion. Physiol Rev (2012) 1.71
Hypoxia reprograms calcium signaling and regulates myoglobin expression. Am J Physiol Cell Physiol (2008) 1.69
RANKL-mediated reactive oxygen species pathway that induces long lasting Ca2+ oscillations essential for osteoclastogenesis. J Biol Chem (2010) 1.58
Slc26a6 regulates CFTR activity in vivo to determine pancreatic duct HCO3- secretion: relevance to cystic fibrosis. EMBO J (2006) 1.56
Gain-of-function mutation in TRPML3 causes the mouse Varitint-Waddler phenotype. J Biol Chem (2007) 1.56
Homer 1 mediates store- and inositol 1,4,5-trisphosphate receptor-dependent translocation and retrieval of TRPC3 to the plasma membrane. J Biol Chem (2006) 1.50
A novel mode of TRPML3 regulation by extracytosolic pH absent in the varitint-waddler phenotype. EMBO J (2008) 1.47
Homer proteins in Ca2+ signaling by excitable and non-excitable cells. Cell Calcium (2007) 1.45
The Ca(2+) channel TRPML3 regulates membrane trafficking and autophagy. Traffic (2009) 1.44
TRPC channels as STIM1-regulated SOCs. Channels (Austin) (2009) 1.43
Congenital chloride-losing diarrhea causing mutations in the STAS domain result in misfolding and mistrafficking of SLC26A3. J Biol Chem (2008) 1.43
Convergent regulation of the lysosomal two-pore channel-2 by Mg²⁺, NAADP, PI(3,5)P₂ and multiple protein kinases. EMBO J (2014) 1.43
The Slc26a4 transporter functions as an electroneutral Cl-/I-/HCO3- exchanger: role of Slc26a4 and Slc26a6 in I- and HCO3- secretion and in regulation of CFTR in the parotid duct. J Physiol (2008) 1.40
Mitochondria and calcium in health and disease. Cell Calcium (2008) 1.39
An endoplasmic reticulum/plasma membrane junction: STIM1/Orai1/TRPCs. FEBS Lett (2009) 1.39
Molecular determinants of fast Ca2+-dependent inactivation and gating of the Orai channels. Proc Natl Acad Sci U S A (2009) 1.38
Deletion of TRPC3 in mice reduces store-operated Ca2+ influx and the severity of acute pancreatitis. Gastroenterology (2009) 1.37
Spinophilin regulates Ca2+ signalling by binding the N-terminal domain of RGS2 and the third intracellular loop of G-protein-coupled receptors. Nat Cell Biol (2005) 1.36
Diverse transport modes by the solute carrier 26 family of anion transporters. J Physiol (2008) 1.35
Native Store-operated Ca2+ Influx Requires the Channel Function of Orai1 and TRPC1. J Biol Chem (2009) 1.34
SLC26A9 is a Cl(-) channel regulated by the WNK kinases. J Physiol (2007) 1.33
IRBIT coordinates epithelial fluid and HCO3- secretion by stimulating the transporters pNBC1 and CFTR in the murine pancreatic duct. J Clin Invest (2008) 1.32
Transient receptor potential mucolipin 1 (TRPML1) and two-pore channels are functionally independent organellar ion channels. J Biol Chem (2011) 1.32
Aberrant localization of intracellular organelles, Ca2+ signaling, and exocytosis in Mist1 null mice. J Biol Chem (2005) 1.30
Spinophilin/neurabin reciprocally regulate signaling intensity by G protein-coupled receptors. EMBO J (2007) 1.29
Dynamic control of cystic fibrosis transmembrane conductance regulator Cl(-)/HCO3(-) selectivity by external Cl(-). J Biol Chem (2004) 1.28
Evolution of calcium homeostasis: from birth of the first cell to an omnipresent signalling system. Cell Calcium (2007) 1.26
Calcium signaling complexes in microdomains of polarized secretory cells. Cell Calcium (2006) 1.24
Pancreatitis: the neglected duct. Gut (2008) 1.22
SLC26A7 is a Cl- channel regulated by intracellular pH. J Biol Chem (2004) 1.22
Polarized but differential localization and recruitment of STIM1, Orai1 and TRPC channels in secretory cells. Traffic (2010) 1.20
Homer 2 tunes G protein-coupled receptors stimulus intensity by regulating RGS proteins and PLCbeta GAP activities. J Cell Biol (2003) 1.20
Signalling specificity in GPCR-dependent Ca2+ signalling. Cell Signal (2003) 1.19
IRBIT governs epithelial secretion in mice by antagonizing the WNK/SPAK kinase pathway. J Clin Invest (2011) 1.18
Reactive oxygen species-mediated TRPC6 protein activation in vascular myocytes, a mechanism for vasoconstrictor-regulated vascular tone. J Biol Chem (2011) 1.17
Borate transport and cell growth and proliferation. Not only in plants. Cell Cycle (2005) 1.15
Irbit mediates synergy between ca(2+) and cAMP signaling pathways during epithelial transport in mice. Gastroenterology (2013) 1.10
AE4 is a DIDS-sensitive Cl(-)/HCO(-)(3) exchanger in the basolateral membrane of the renal CCD and the SMG duct. Am J Physiol Cell Physiol (2002) 1.10
A new mode of Ca2+ signaling by G protein-coupled receptors: gating of IP3 receptor Ca2+ release channels by Gbetagamma. Curr Biol (2003) 1.08
The STIM1 CTID domain determines access of SARAF to SOAR to regulate Orai1 channel function. J Cell Biol (2013) 1.07
The cystic fibrosis transmembrane conductance regulator interacts with and regulates the activity of the HCO3- salvage transporter human Na+-HCO3- cotransport isoform 3. J Biol Chem (2002) 1.06
Determinants of coupled transport and uncoupled current by the electrogenic SLC26 transporters. J Gen Physiol (2011) 1.05
Membrane potential regulates nicotinic acid adenine dinucleotide phosphate (NAADP) dependence of the pH- and Ca2+-sensitive organellar two-pore channel TPC1. J Biol Chem (2012) 1.04
Regulatory interaction between CFTR and the SLC26 transporters. Novartis Found Symp (2006) 1.04
TRPpathies. J Physiol (2006) 1.04
STIM1-dependent and STIM1-independent function of transient receptor potential canonical (TRPC) channels tunes their store-operated mode. J Biol Chem (2010) 1.03
Genetic and pharmacologic inhibition of the Ca2+ influx channel TRPC3 protects secretory epithelia from Ca2+-dependent toxicity. Gastroenterology (2011) 1.02
A role for the Ca2+ channel TRPML1 in gastric acid secretion, based on analysis of knockout mice. Gastroenterology (2010) 1.01
Acidic Ca(2+) stores come to the fore. Cell Calcium (2011) 1.00
ER stress disrupts Ca2+-signaling complexes and Ca2+ regulation in secretory and muscle cells from PERK-knockout mice. J Cell Sci (2005) 0.98
Convergence of IRBIT, phosphatidylinositol (4,5) bisphosphate, and WNK/SPAK kinases in regulation of the Na+-HCO3- cotransporters family. Proc Natl Acad Sci U S A (2013) 0.97
Multiple effects of SERCA2b mutations associated with Darier's disease. J Biol Chem (2003) 0.97
Selective Gαi subunits as novel direct activators of transient receptor potential canonical (TRPC)4 and TRPC5 channels. J Biol Chem (2012) 0.97
Cell-specific behavior of P2X7 receptors in mouse parotid acinar and duct cells. J Biol Chem (2003) 0.97
Protein-protein interaction and functionTRPC channels. Pflugers Arch (2005) 0.97
Peptidyl-prolyl isomerase FKBP52 controls chemotropic guidance of neuronal growth cones via regulation of TRPC1 channel opening. Neuron (2009) 0.96
Ca2+ signaling in microdomains: Homer1 mediates the interaction between RyR2 and Cav1.2 to regulate excitation-contraction coupling. J Biol Chem (2007) 0.94
The WNK/SPAK and IRBIT/PP1 pathways in epithelial fluid and electrolyte transport. Physiology (Bethesda) (2012) 0.94
The intracellular Ca²⁺ channels of membrane traffic. Channels (Austin) (2012) 0.93
Molecular determinants mediating gating of Transient Receptor Potential Canonical (TRPC) channels by stromal interaction molecule 1 (STIM1). J Biol Chem (2014) 0.93
Properties of the TRPML3 channel pore and its stable expansion by the Varitint-Waddler-causing mutation. J Biol Chem (2010) 0.92
Aberrant Ca2+ handling in lysosomal storage disorders. Cell Calcium (2010) 0.91
Role of regulator of G protein signaling 2 (RGS2) in Ca(2+) oscillations and adaptation of Ca(2+) signaling to reduce excitability of RGS2-/- cells. J Biol Chem (2004) 0.91
Regulation of the P2X7 receptor permeability to large molecules by extracellular Cl- and Na+. J Biol Chem (2005) 0.90
TRPML: transporters of metals in lysosomes essential for cell survival? Cell Calcium (2011) 0.88