Published in J Am Soc Nephrol on April 16, 2008
Increased expression of NAD(P)H oxidase subunit p67(phox) in the renal medulla contributes to excess oxidative stress and salt-sensitive hypertension. Cell Metab (2012) 2.18
Renal medullary microRNAs in Dahl salt-sensitive rats: miR-29b regulates several collagens and related genes. Hypertension (2010) 1.94
MicroRNA-target pairs in human renal epithelial cells treated with transforming growth factor beta 1: a novel role of miR-382. Nucleic Acids Res (2010) 1.42
Effects of renal perfusion pressure on renal medullary hydrogen peroxide and nitric oxide production. Hypertension (2009) 1.09
Creation and characterization of a renin knockout rat. Hypertension (2011) 1.09
Infiltrating immune cells in the kidney in salt-sensitive hypertension and renal injury. Am J Physiol Renal Physiol (2014) 1.07
Deficiency of renal cortical EGF increases ENaC activity and contributes to salt-sensitive hypertension. J Am Soc Nephrol (2013) 1.04
Epigenomics of hypertension. Semin Nephrol (2013) 1.00
Evaluation of metalloprotease inhibitors on hypertension and diabetic nephropathy. Am J Physiol Renal Physiol (2011) 0.99
Carbonyl stress induces hypertension and cardio-renal vascular injury in Dahl salt-sensitive rats. Hypertens Res (2013) 0.96
Hypertension-induced vascular remodeling contributes to reduced cerebral perfusion and the development of spontaneous stroke in aged SHRSP rats. J Cereb Blood Flow Metab (2009) 0.96
Silencing of hypoxia-inducible factor-1α gene attenuated angiotensin II-induced renal injury in Sprague-Dawley rats. Hypertension (2011) 0.96
Progression of glomerular filtration rate reduction determined in conscious Dahl salt-sensitive hypertensive rats. Hypertension (2013) 0.96
Role of renal perfusion pressure versus angiotensin II on renal oxidative stress in angiotensin II-induced hypertensive rats. Hypertension (2010) 0.95
Pressure-induced renal injury in angiotensin II versus norepinephrine-induced hypertensive rats. Hypertension (2009) 0.95
Reactive oxygen species as important determinants of medullary flow, sodium excretion, and hypertension. Am J Physiol Renal Physiol (2014) 0.95
Increased proliferative cells in the medullary thick ascending limb of the loop of Henle in the Dahl salt-sensitive rat. Hypertension (2012) 0.92
Renal injury in angiotensin II+L-NAME-induced hypertensive rats is independent of elevated blood pressure. Am J Physiol Renal Physiol (2011) 0.91
Enhanced amiloride-sensitive superoxide production in renal medullary thick ascending limb of Dahl salt-sensitive rats. Am J Physiol Renal Physiol (2008) 0.90
Pentosan polysulfate treatment preserves renal autoregulation in ANG II-infused hypertensive rats via normalization of P2X1 receptor activation. Am J Physiol Renal Physiol (2010) 0.89
Antithrombin III/SerpinC1 insufficiency exacerbates renal ischemia/reperfusion injury. Kidney Int (2015) 0.89
Arterial stiffening provides sufficient explanation for primary hypertension. PLoS Comput Biol (2014) 0.88
Evidence of the Importance of Nox4 in Production of Hypertension in Dahl Salt-Sensitive Rats. Hypertension (2015) 0.85
Ultrastructure of mitochondria and the endoplasmic reticulum in renal tubules of Dahl salt-sensitive rats. Am J Physiol Renal Physiol (2014) 0.83
Null mutation of the nicotinamide adenine dinucleotide phosphate-oxidase subunit p67phox protects the Dahl-S rat from salt-induced reductions in medullary blood flow and glomerular filtration rate. Hypertension (2014) 0.83
Albuminuria indicates the pressure-associated injury of juxtamedullary nephrons and cerebral strain vessels in spontaneously hypertensive stroke-prone rats. Hypertens Res (2012) 0.81
Renal Tumor Necrosis Factor α Contributes to Hypertension in Dahl Salt-Sensitive Rats. Sci Rep (2016) 0.81
Mycophenolate mofetil prevents high-fat diet-induced hypertension and renal glomerular injury in Dahl SS rats. Physiol Rep (2013) 0.80
PhenoMiner: a quantitative phenotype database for the laboratory rat, Rattus norvegicus. Application in hypertension and renal disease. Database (Oxford) (2015) 0.79
Oxidative stress-induced glomerular mineralocorticoid receptor activation limits the benefit of salt reduction in Dahl salt-sensitive rats. PLoS One (2012) 0.78
Telemetric signal-driven servocontrol of renal perfusion pressure in acute and chronic rat experiments. Am J Physiol Regul Integr Comp Physiol (2008) 0.77
Progression of glomerular and tubular disease in pediatrics. Semin Nephrol (2009) 0.77
A Kidney-selective Biopolymer for Targeted Drug Delivery. Am J Physiol Renal Physiol (2016) 0.76
Lack of Effects of Metformin and AICAR Chronic Infusion on the Development of Hypertension in Dahl Salt-Sensitive Rats. Front Physiol (2017) 0.75
Mycophenolate Mofetil Prevents Cerebrovascular Injury in Stroke-prone Spontaneously Hypertensive Rats. Physiol Genomics (2016) 0.75
A new mouse model of hemorrhagic shock-induced acute kidney injury. Am J Physiol Renal Physiol (2016) 0.75
Proton channels and renal hypertensive injury: a key piece of the Dahl salt-sensitive rat puzzle? Am J Physiol Regul Integr Comp Physiol (2016) 0.75
Salt-induced epithelial-to-mesenchymal transition in Dahl salt-sensitive rats is dependent on elevated blood pressure. Braz J Med Biol Res (2014) 0.75
p66Shc regulates renal vascular tone in hypertension-induced nephropathy. J Clin Invest (2016) 0.75
Myofibroblasts and mechano-regulation of connective tissue remodelling. Nat Rev Mol Cell Biol (2002) 14.80
Epithelial-mesenchymal transition and its implications for fibrosis. J Clin Invest (2003) 12.56
Effect of blood pressure lowering and antihypertensive drug class on progression of hypertensive kidney disease: results from the AASK trial. JAMA (2002) 12.29
Blood pressure control, proteinuria, and the progression of renal disease. The Modification of Diet in Renal Disease Study. Ann Intern Med (1995) 5.50
Racial differences in the incidence of treatment for end-stage renal disease. N Engl J Med (1982) 4.48
Dissection of key events in tubular epithelial to myofibroblast transition and its implications in renal interstitial fibrosis. Am J Pathol (2001) 4.39
Renal function change in hypertensive members of the Multiple Risk Factor Intervention Trial. Racial and treatment effects. The MRFIT Research Group. JAMA (1992) 3.86
Role of pressure in angiotensin II-induced renal injury: chronic servo-control of renal perfusion pressure in rats. Hypertension (2004) 2.13
NADPH oxidase in the renal medulla causes oxidative stress and contributes to salt-sensitive hypertension in Dahl S rats. Hypertension (2006) 1.99
Brown Norway chromosome 13 confers protection from high salt to consomic Dahl S rat. Hypertension (2001) 1.99
Role of matrix metalloproteinases in renal pathophysiologies. Am J Physiol Renal Physiol (2006) 1.79
Production and actions of superoxide in the renal medulla. Hypertension (2001) 1.76
Expression, roles, receptors, and regulation of osteopontin in the kidney. Kidney Int (2001) 1.66
Role of renal NO production in the regulation of medullary blood flow. Am J Physiol Regul Integr Comp Physiol (2003) 1.52
Development and characteristics of inbred strains of Dahl salt-sensitive and salt-resistant rats. Hypertension (1985) 1.43
Enhanced superoxide production in renal outer medulla of Dahl salt-sensitive rats reduces nitric oxide tubular-vascular cross-talk. Hypertension (2007) 1.27
Effect of sodium delivery on superoxide and nitric oxide in the medullary thick ascending limb. Am J Physiol Renal Physiol (2006) 1.26
Use of a three-color cDNA microarray platform to measure and control support-bound probe for improved data quality and reproducibility. Nucleic Acids Res (2003) 1.25
Enhanced chloride reabsorption in the loop of Henle in Dahl salt-sensitive rats. Hypertension (1991) 1.25
Renal oxidative stress in medullary thick ascending limbs produced by elevated NaCl and glucose. Hypertension (2004) 1.23
Tissue-specific transcriptome responses in rats with early streptozotocin-induced diabetes. Physiol Genomics (2005) 1.20
Three color cDNA microarrays: quantitative assessment through the use of fluorescein-labeled probes. Nucleic Acids Res (2003) 1.18
Renal and nephron hemodynamics in spontaneously hypertensive rats. Am J Physiol (1979) 1.17
Superoxide dismutase and oxidative stress in Dahl salt-sensitive and -resistant rats. Am J Physiol Regul Integr Comp Physiol (2002) 1.16
Effects of blood pressure control on progressive renal disease in blacks and whites. Modification of Diet in Renal Disease Study Group. Hypertension (1997) 1.16
Influence of diet and genetics on hypertension and renal disease in Dahl salt-sensitive rats. Physiol Genomics (2004) 1.15
Osteopontin expression in angiotensin II-induced tubulointerstitial nephritis. Kidney Int (1994) 1.15
Insights into Dahl salt-sensitive hypertension revealed by temporal patterns of renal medullary gene expression. Physiol Genomics (2003) 1.14
Renal medullary genes in salt-sensitive hypertension: a chromosomal substitution and cDNA microarray study. Physiol Genomics (2002) 1.10
Abnormal renal hemodynamics and pressure-natriuresis relationship in Dahl salt-sensitive rats. Am J Physiol (1986) 1.09
A functional role for osteopontin in experimental crescentic glomerulonephritis in the rat. Proc Assoc Am Physicians (1998) 1.08
Effect of high glucose on gene expression in mesangial cells: upregulation of the thiol pathway is an adaptational response. Physiol Genomics (2004) 1.08
Impaired myogenic responsiveness of renal microvessels in Dahl salt-sensitive rats. Circ Res (1992) 1.06
Hypertensive nephrosclerosis in the Dahl/Rapp rat. Initial sites of injury and effect of dietary L-arginine supplementation. Lab Invest (1993) 1.05
Effects of monotherapy of temocapril or candesartan with dose increments or combination therapy with both drugs on the suppression of diabetic nephropathy. Hypertens Res (2007) 1.04
Genetic linkage of albuminuria and renal injury in Dahl salt-sensitive rats on a high-salt diet: comparison with spontaneously hypertensive rats. Physiol Genomics (2004) 0.98
Quantitative assessment of the importance of dye switching and biological replication in cDNA microarray studies. Physiol Genomics (2003) 0.97
Early and persistent up-regulated expression of renal cortical osteopontin in experimental hydronephrosis. Am J Pathol (1995) 0.97
Role of hypertension in progressive glomerular immune injury. Hypertension (1985) 0.96
Dynamic autoregulation and renal injury in Dahl rats. Hypertension (1997) 0.96
Pressure natriuresis and cortical and papillary blood flow in inbred Dahl rats. Am J Physiol (1991) 0.95
Tubulointerstitial injury and loss of nitric oxide synthases parallel the development of hypertension in the Dahl-SS rat. J Hypertens (2000) 0.95
High throughput gene expression profiling: a molecular approach to integrative physiology. J Physiol (2004) 0.93
Upregulation of osteopontin expression in renal cortex of streptozotocin-induced diabetic rats is mediated by bradykinin. Diabetes (1998) 0.89
Osteopontin expression in progressive renal injury in remnant kidney: role of angiotensin II. Kidney Int (2000) 0.88
Nitric oxide synthase activity and renal injury in genetic hypertension. Hypertension (1998) 0.87
Interferon gamma attenuates hypertensive renal injury in salt-sensitive Dahl rats. Hypertension (1992) 0.85
Pressure-induced constriction of the afferent arteriole of spontaneously hypertensive rats. Hypertension (1992) 0.83
Transcriptome analysis and kidney research: toward systems biology. Kidney Int (2005) 0.82
Salt in health and disease--a delicate balance. N Engl J Med (2013) 3.49
Efficient transgenic rat production by a lentiviral vector. Am J Physiol Heart Circ Physiol (2007) 3.07
MicroRNA-target pairs in the rat kidney identified by microRNA microarray, proteomic, and bioinformatic analysis. Genome Res (2008) 2.51
Characterization of human plasma-derived exosomal RNAs by deep sequencing. BMC Genomics (2013) 2.27
Increased expression of NAD(P)H oxidase subunit p67(phox) in the renal medulla contributes to excess oxidative stress and salt-sensitive hypertension. Cell Metab (2012) 2.18
Role of pressure in angiotensin II-induced renal injury: chronic servo-control of renal perfusion pressure in rats. Hypertension (2004) 2.13
Delayed ischemic preconditioning contributes to renal protection by upregulation of miR-21. Kidney Int (2012) 2.12
The miR-29 family: genomics, cell biology, and relevance to renal and cardiovascular injury. Physiol Genomics (2012) 2.08
NADPH oxidase in the renal medulla causes oxidative stress and contributes to salt-sensitive hypertension in Dahl S rats. Hypertension (2006) 1.99
Renal medullary microRNAs in Dahl salt-sensitive rats: miR-29b regulates several collagens and related genes. Hypertension (2010) 1.94
Multiple blood pressure loci on rat chromosome 13 attenuate development of hypertension in the Dahl S hypertensive rat. Physiol Genomics (2007) 1.57
Genome-wide scan for linkage to obesity-associated hypertension in French Canadians. Hypertension (2005) 1.55
Analyzing complex traits with congenic strains. Mamm Genome (2010) 1.43
Role of 20-hydroxyeicosatetraenoic acid in the renal and vasoconstrictor actions of angiotensin II. Am J Physiol Regul Integr Comp Physiol (2002) 1.43
Xenon Protects Against Septic Acute Kidney Injury via miR-21 Target Signaling Pathway. Crit Care Med (2015) 1.42
MicroRNA-target pairs in human renal epithelial cells treated with transforming growth factor beta 1: a novel role of miR-382. Nucleic Acids Res (2010) 1.42
MicroRNA: a new frontier in kidney and blood pressure research. Am J Physiol Renal Physiol (2009) 1.41
Tubulovascular nitric oxide crosstalk: buffering of angiotensin II-induced medullary vasoconstriction. Circ Res (2002) 1.40
Angiotensin II-NAD(P)H oxidase-stimulated superoxide modifies tubulovascular nitric oxide cross-talk in renal outer medulla. Hypertension (2003) 1.38
Chromosome substitution reveals the genetic basis of Dahl salt-sensitive hypertension and renal disease. Am J Physiol Renal Physiol (2008) 1.37
Genomic map of cardiovascular phenotypes of hypertension in female Dahl S rats. Physiol Genomics (2003) 1.37
Effect of renal medullary H2O2 on salt-induced hypertension and renal injury. Am J Physiol Regul Integr Comp Physiol (2005) 1.36
Report of the National Heart, Lung, and Blood Institute Working Group on epigenetics and hypertension. Hypertension (2012) 1.28
Enhanced superoxide production in renal outer medulla of Dahl salt-sensitive rats reduces nitric oxide tubular-vascular cross-talk. Hypertension (2007) 1.27
Effect of sodium delivery on superoxide and nitric oxide in the medullary thick ascending limb. Am J Physiol Renal Physiol (2006) 1.26
Novel role of fumarate metabolism in dahl-salt sensitive hypertension. Hypertension (2009) 1.25
Chromosomal mapping of the genetic basis of hypertension and renal disease in FHH rats. Am J Physiol Renal Physiol (2007) 1.24
Increased renal medullary oxidative stress produces hypertension. Hypertension (2002) 1.24
Renal oxidative stress in medullary thick ascending limbs produced by elevated NaCl and glucose. Hypertension (2004) 1.23
Increased renal medullary H2O2 leads to hypertension. Hypertension (2003) 1.23
Low-dose dioxins alter gene expression related to cholesterol biosynthesis, lipogenesis, and glucose metabolism through the aryl hydrocarbon receptor-mediated pathway in mouse liver. Toxicol Appl Pharmacol (2008) 1.21
Molecular networks in Dahl salt-sensitive hypertension based on transcriptome analysis of a panel of consomic rats. Physiol Genomics (2008) 1.21
Identification of persistently altered gene expression in the kidney after functional recovery from ischemic acute renal failure. Am J Physiol Renal Physiol (2005) 1.21
Renal regional proteomes in young Dahl salt-sensitive rats. Hypertension (2008) 1.20
Tissue-specific transcriptome responses in rats with early streptozotocin-induced diabetes. Physiol Genomics (2005) 1.20
Influence of diet and genetics on hypertension and renal disease in Dahl salt-sensitive rats. Physiol Genomics (2004) 1.15
Identifying physiological origins of baroreflex dysfunction in salt-sensitive hypertension in the Dahl SS rat. Physiol Genomics (2010) 1.15
Glucocorticoid response elements and 11 beta-hydroxysteroid dehydrogenases in the regulation of endothelial nitric oxide synthase expression. Cardiovasc Res (2008) 1.15
Insights into Dahl salt-sensitive hypertension revealed by temporal patterns of renal medullary gene expression. Physiol Genomics (2003) 1.14
Temporomandibular disorders and associated clinical comorbidities. Clin J Pain (2011) 1.12
Renal medullary genes in salt-sensitive hypertension: a chromosomal substitution and cDNA microarray study. Physiol Genomics (2002) 1.10
Effects of renal perfusion pressure on renal medullary hydrogen peroxide and nitric oxide production. Hypertension (2009) 1.09
BN phenome: detailed characterization of the cardiovascular, renal, and pulmonary systems of the sequenced rat. Physiol Genomics (2006) 1.09
Effect of high glucose on gene expression in mesangial cells: upregulation of the thiol pathway is an adaptational response. Physiol Genomics (2004) 1.08
Dynamic convergence and divergence of renal genomic and biological pathways in protection from Dahl salt-sensitive hypertension. Physiol Genomics (2009) 1.06
Hyperaldosteronism and hypertension: ethnic differences. Hypertension (2005) 1.05
Renal medullary 11 beta-hydroxysteroid dehydrogenase type 1 in Dahl salt-sensitive hypertension. Physiol Genomics (2008) 1.04
Deficiency of renal cortical EGF increases ENaC activity and contributes to salt-sensitive hypertension. J Am Soc Nephrol (2013) 1.04
miR-29c is downregulated in renal interstitial fibrosis in humans and rats and restored by HIF-α activation. Am J Physiol Renal Physiol (2013) 1.03
Increased H(2)O(2) counteracts the vasodilator and natriuretic effects of superoxide dismutation by tempol in renal medulla. Am J Physiol Regul Integr Comp Physiol (2003) 1.03
MiR-382 targeting of kallikrein 5 contributes to renal inner medullary interstitial fibrosis. Physiol Genomics (2011) 1.02
NO synthase uncoupling in the kidney of Dahl S rats: role of dihydrobiopterin. Hypertension (2006) 1.01
MicroRNAs contribute to the maintenance of cell-type-specific physiological characteristics: miR-192 targets Na+/K+-ATPase β1. Nucleic Acids Res (2012) 1.01
Epigenomics of hypertension. Semin Nephrol (2013) 1.00
Renal medullary nitric oxide deficit of Dahl S rats enhances hypertensive actions of angiotensin II. Am J Physiol Regul Integr Comp Physiol (2002) 1.00
miR-21 contributes to xenon-conferred amelioration of renal ischemia-reperfusion injury in mice. Anesthesiology (2013) 0.99
Mitochondrial proteomic analysis reveals deficiencies in oxygen utilization in medullary thick ascending limb of Henle in the Dahl salt-sensitive rat. Physiol Genomics (2012) 0.99
Phosducin influences sympathetic activity and prevents stress-induced hypertension in humans and mice. J Clin Invest (2009) 0.98
Suppression of 11beta-hydroxysteroid dehydrogenase type 1 with RNA interference substantially attenuates 3T3-L1 adipogenesis. Physiol Genomics (2007) 0.98
Quantitative assessment of the importance of dye switching and biological replication in cDNA microarray studies. Physiol Genomics (2003) 0.97
Systematic, genome-wide, sex-specific linkage of cardiovascular traits in French Canadians. Hypertension (2008) 0.97
Substitution of chromosome 1 ameliorates L-NAME hypertension and renal disease in the fawn-hooded hypertensive rat. Am J Physiol Renal Physiol (2005) 0.97
Carbonyl stress induces hypertension and cardio-renal vascular injury in Dahl salt-sensitive rats. Hypertens Res (2013) 0.96
Role of renal perfusion pressure versus angiotensin II on renal oxidative stress in angiotensin II-induced hypertensive rats. Hypertension (2010) 0.95
Pressure-induced renal injury in angiotensin II versus norepinephrine-induced hypertensive rats. Hypertension (2009) 0.95
Increase of sodium delivery stimulates the mitochondrial respiratory chain H2O2 production in rat renal medullary thick ascending limb. Am J Physiol Renal Physiol (2011) 0.95
Narrowing a region on rat chromosome 13 that protects against hypertension in Dahl SS-13BN congenic strains. Am J Physiol Heart Circ Physiol (2011) 0.95
Non-replication study of a genome-wide association study for hypertension and blood pressure in African Americans. BMC Med Genet (2012) 0.95
Real-time electrochemical detection of ATP and H₂O₂ release in freshly isolated kidneys. Am J Physiol Renal Physiol (2013) 0.94
Modulation of pressure-natriuresis by renal medullary reactive oxygen species and nitric oxide. Curr Hypertens Rep (2010) 0.94
Base-resolution maps of 5-methylcytosine and 5-hydroxymethylcytosine in Dahl S rats: effect of salt and genomic sequence. Hypertension (2014) 0.94
Consomic strategies to localize genomic regions related to vascular reactivity in the Dahl salt-sensitive rat. Physiol Genomics (2006) 0.93
High throughput gene expression profiling: a molecular approach to integrative physiology. J Physiol (2004) 0.93
Vasopressin-induced nitric oxide production in rat inner medullary collecting duct is dependent on V2 receptor activation of the phosphoinositide pathway. Am J Physiol Renal Physiol (2007) 0.92
Increased proliferative cells in the medullary thick ascending limb of the loop of Henle in the Dahl salt-sensitive rat. Hypertension (2012) 0.92
Characteristics of microRNAs enriched in specific cell types and primary tissue types in solid organs. Physiol Genomics (2013) 0.91
Renal injury in angiotensin II+L-NAME-induced hypertensive rats is independent of elevated blood pressure. Am J Physiol Renal Physiol (2011) 0.91
NSAIDs acutely inhibit TRPC channels in freshly isolated rat glomeruli. Biochem Biophys Res Commun (2011) 0.90
A novel amiloride-sensitive h+ transport pathway mediates enhanced superoxide production in thick ascending limb of salt-sensitive rats, not na+/h+ exchange. Hypertension (2009) 0.90
Molecular mechanisms and therapeutic strategies of chronic renal injury: physiological role of angiotensin II-induced oxidative stress in renal medulla. J Pharmacol Sci (2006) 0.90
Enhanced amiloride-sensitive superoxide production in renal medullary thick ascending limb of Dahl salt-sensitive rats. Am J Physiol Renal Physiol (2008) 0.90
RNASeq-derived transcriptome comparisons reveal neuromodulatory deficiency in the CO2 insensitive brown Norway rat. J Physiol (2014) 0.90