Published in Curr Opin Crit Care on June 01, 2008
Pathophysiology and treatment of septic shock in neonates. Clin Perinatol (2010) 1.17
Hydrogel-embedded endothelial progenitor cells evade LPS and mitigate endotoxemia. Am J Physiol Renal Physiol (2011) 0.91
CXCL12/CXCR4 signaling and other recruitment and homing pathways in fracture repair. Bonekey Rep (2013) 0.87
Stem cell-derived endothelial cells for cardiovascular disease: a therapeutic perspective. Br J Clin Pharmacol (2013) 0.84
Vascular precursor cells in tissue injury repair. Transl Res (2017) 0.75
Endothelial progenitors in sepsis: vox clamantis in deserto? Crit Care (2011) 0.75
The epidemiology of sepsis in the United States from 1979 through 2000. N Engl J Med (2003) 32.30
Isolation of putative progenitor endothelial cells for angiogenesis. Science (1997) 30.27
Efficacy and safety of recombinant human activated protein C for severe sepsis. N Engl J Med (2001) 27.70
Mechanisms of angiogenesis. Nature (1997) 18.04
Circulating endothelial progenitor cells, vascular function, and cardiovascular risk. N Engl J Med (2003) 13.84
Sepsis in European intensive care units: results of the SOAP study. Crit Care Med (2006) 11.78
Progenitor cell trafficking is regulated by hypoxic gradients through HIF-1 induction of SDF-1. Nat Med (2004) 11.71
Intracoronary bone marrow-derived progenitor cells in acute myocardial infarction. N Engl J Med (2006) 11.66
Bone marrow origin of endothelial progenitor cells responsible for postnatal vasculogenesis in physiological and pathological neovascularization. Circ Res (1999) 11.32
The physiological disturbances produced by endotoxins. Annu Rev Physiol (1954) 10.40
Ischemia- and cytokine-induced mobilization of bone marrow-derived endothelial progenitor cells for neovascularization. Nat Med (1999) 10.16
Expression of VEGFR-2 and AC133 by circulating human CD34(+) cells identifies a population of functional endothelial precursors. Blood (2000) 9.24
Intracoronary injection of mononuclear bone marrow cells in acute myocardial infarction. N Engl J Med (2006) 7.28
Identification of a novel hierarchy of endothelial progenitor cells using human peripheral and umbilical cord blood. Blood (2004) 7.21
Therapeutic stem and progenitor cell transplantation for organ vascularization and regeneration. Nat Med (2003) 7.14
Transcoronary transplantation of progenitor cells after myocardial infarction. N Engl J Med (2006) 6.77
VEGF contributes to postnatal neovascularization by mobilizing bone marrow-derived endothelial progenitor cells. EMBO J (1999) 6.62
Transplantation of ex vivo expanded endothelial progenitor cells for therapeutic neovascularization. Proc Natl Acad Sci U S A (2000) 6.59
Transplantation of Progenitor Cells and Regeneration Enhancement in Acute Myocardial Infarction (TOPCARE-AMI). Circulation (2002) 6.50
Persistent microcirculatory alterations are associated with organ failure and death in patients with septic shock. Crit Care Med (2004) 5.90
Origins of circulating endothelial cells and endothelial outgrowth from blood. J Clin Invest (2000) 5.88
Intrapulmonary delivery of bone marrow-derived mesenchymal stem cells improves survival and attenuates endotoxin-induced acute lung injury in mice. J Immunol (2007) 5.66
The role of the endothelium in severe sepsis and multiple organ dysfunction syndrome. Blood (2003) 5.22
Septic shock in humans. Advances in the understanding of pathogenesis, cardiovascular dysfunction, and therapy. Ann Intern Med (1990) 5.15
Anti-inflammatory cytokines. Chest (2000) 4.74
Origin of endothelial progenitors in human postnatal bone marrow. J Clin Invest (2002) 4.38
Hematopoietic stem cells: the paradigmatic tissue-specific stem cell. Am J Pathol (2006) 4.32
Epidemiology of sepsis and infection in ICU patients from an international multicentre cohort study. Intensive Care Med (2001) 3.95
Prevention of LPS-induced acute lung injury in mice by mesenchymal stem cells overexpressing angiopoietin 1. PLoS Med (2007) 3.64
Epidemiology of severe sepsis occurring in the first 24 hrs in intensive care units in England, Wales, and Northern Ireland. Crit Care Med (2003) 3.39
Adult-population incidence of severe sepsis in Australian and New Zealand intensive care units. Intensive Care Med (2004) 3.30
Transplanted cord blood-derived endothelial precursor cells augment postnatal neovascularization. J Clin Invest (2000) 2.96
Prevention of endotoxin-induced systemic response by bone marrow-derived mesenchymal stem cells in mice. Am J Physiol Lung Cell Mol Physiol (2007) 2.88
The endothelial cell protein C receptor augments protein C activation by the thrombin-thrombomodulin complex. Proc Natl Acad Sci U S A (1996) 2.58
Intravenous transfusion of endothelial progenitor cells reduces neointima formation after vascular injury. Circ Res (2003) 2.56
Increased circulating endothelial progenitor cells are associated with survival in acute lung injury. Am J Respir Crit Care Med (2005) 2.33
Expression of tissue factor, thrombomodulin, and E-selectin in baboons with lethal Escherichia coli sepsis. Am J Pathol (1993) 2.27
Bone marrow-derived progenitor cells are important for lung repair after lipopolysaccharide-induced lung injury. J Immunol (2004) 2.25
Transplantation of autologous endothelial progenitor cells may be beneficial in patients with idiopathic pulmonary arterial hypertension: a pilot randomized controlled trial. J Am Coll Cardiol (2007) 2.23
Working hypothesis to redefine endothelial progenitor cells. Leukemia (2007) 2.03
Regulation of blood coagulation. Biochim Biophys Acta (2000) 1.97
Characterization of a mouse model for thrombomodulin deficiency. Arterioscler Thromb Vasc Biol (2001) 1.76
Endothelial cell apoptosis in angiogenesis and vessel regression. Circ Res (2000) 1.73
Non-hematopoietic EPCR regulates the coagulation and inflammatory responses during endotoxemia. J Thromb Haemost (2007) 1.73
Infection and inflammation and the coagulation system. Cardiovasc Res (2003) 1.49
Circulating endothelial cells in patients with septic shock. Am J Respir Crit Care Med (2001) 1.41
Mechanisms in the production of tissue damage and shock by endotoxins. Trans Assoc Am Physicians (1957) 1.36
Sepsis and disseminated intravascular coagulation. J Thromb Thrombolysis (2004) 1.36
Increased circulating endothelial progenitor cells in septic patients: correlation with survival. Crit Care Med (2007) 1.32
Increased circulating endothelial progenitor cells in patients with bacterial pneumonia: evidence that bone marrow derived cells contribute to lung repair. Thorax (2005) 1.27
Extrinsic coagulation blockade attenuates lung injury and proinflammatory cytokine release after intratracheal lipopolysaccharide. Am J Respir Cell Mol Biol (2002) 1.25
Endothelial cell apoptosis in lipopolysaccharide-induced lung injury in mice. Int Arch Allergy Immunol (1998) 1.15
Peripheral infusion of rat bone marrow derived endothelial progenitor cells leads to homing in acute lung injury. Respir Res (2007) 1.14
Human endothelial cell response to gram-negative lipopolysaccharide assessed with cDNA microarrays. Am J Physiol Cell Physiol (2001) 1.11
Characterization of endothelial-like cells derived from human mesenchymal stem cells. J Thromb Haemost (2007) 1.09
Endothelial progenitor cell transplantation improves the survival following liver injury in mice. Gastroenterology (2006) 1.02
Endothelial cell dysfunction and coagulation. Crit Care Med (2001) 0.99
Inhibition of hypoxia-inducible factor-1alpha and endothelial progenitor cell differentiation by adenoviral transfer of small interfering RNA in vitro. J Vasc Res (2006) 0.90
Kinetics of progenitor hemopoetic stem cells in sepsis: correlation with patients survival? BMC Infect Dis (2006) 0.84
Endothelial progenitor cells as therapeutic vectors in cardiovascular disorders: from experimental models to human trials. Pharmacol Ther (2007) 0.84
Ipr1 gene mediates innate immunity to tuberculosis. Nature (2005) 4.53
Targeted deletion of Dicer in the heart leads to dilated cardiomyopathy and heart failure. Proc Natl Acad Sci U S A (2008) 4.00
Recent trends in acute lung injury mortality: 1996-2005. Crit Care Med (2009) 3.86
Expression of microRNAs is dynamically regulated during cardiomyocyte hypertrophy. J Mol Cell Cardiol (2007) 3.67
Accurate characterization of extravascular lung water in acute respiratory distress syndrome. Crit Care Med (2008) 2.94
Prevention of endotoxin-induced systemic response by bone marrow-derived mesenchymal stem cells in mice. Am J Physiol Lung Cell Mol Physiol (2007) 2.88
Seasonal variation in the epidemiology of sepsis. Crit Care Med (2007) 2.46
Alcohol dependence is independently associated with sepsis, septic shock, and hospital mortality among adult intensive care unit patients. Crit Care Med (2007) 2.42
Increased circulating endothelial progenitor cells are associated with survival in acute lung injury. Am J Respir Crit Care Med (2005) 2.33
Albumin: biochemical properties and therapeutic potential. Hepatology (2005) 2.26
The role of infection and comorbidity: Factors that influence disparities in sepsis. Crit Care Med (2006) 2.21
Racial and ethnic disparities in mortality from acute lung injury. Crit Care Med (2009) 2.14
Flagellin treatment protects against chemicals, bacteria, viruses, and radiation. J Immunol (2008) 2.07
Control of virus reactivation arrests pulmonary herpesvirus-induced fibrosis in IFN-gamma receptor-deficient mice. Am J Respir Crit Care Med (2007) 2.05
Targeted deletion of metalloproteinase 9 attenuates experimental colitis in mice: central role of epithelial-derived MMP. Gastroenterology (2005) 2.03
Albumin influences total plasma antioxidant capacity favorably in patients with acute lung injury. Crit Care Med (2004) 1.88
The epidemiology of sepsis in patients with malignancy. Chest (2006) 1.87
Activation of alveolar macrophages via the alternative pathway in herpesvirus-induced lung fibrosis. Am J Respir Cell Mol Biol (2006) 1.75
Sepsis: the future is bright. Crit Care Med (2006) 1.72
Trends in the incidence of noncardiogenic acute respiratory failure: the role of race. Crit Care Med (2012) 1.67
Stem cells and cell therapies in lung biology and lung diseases. Proc Am Thorac Soc (2011) 1.66
The effect of diabetes mellitus on organ dysfunction with sepsis: an epidemiological study. Crit Care (2009) 1.65
Clinical review: Update on hemodynamic monitoring--a consensus of 16. Crit Care (2011) 1.62
Role of the SDF-1/CXCR4 axis in the pathogenesis of lung injury and fibrosis. Am J Respir Cell Mol Biol (2007) 1.61
Anti-inflammatory effects of mesenchymal stem cells: novel concept for future therapies. Expert Opin Biol Ther (2008) 1.59
Lung infection with gamma-herpesvirus induces progressive pulmonary fibrosis in Th2-biased mice. Am J Physiol Lung Cell Mol Physiol (2005) 1.56
Cardiac response to pressure overload in 129S1/SvImJ and C57BL/6J mice: temporal- and background-dependent development of concentric left ventricular hypertrophy. Am J Physiol Heart Circ Physiol (2006) 1.52
Structure, process, and annual ICU mortality across 69 centers: United States Critical Illness and Injury Trials Group Critical Illness Outcomes Study. Crit Care Med (2014) 1.48
Wnt1/βcatenin injury response activates the epicardium and cardiac fibroblasts to promote cardiac repair. EMBO J (2011) 1.47
Navigating the institutional review board approval process in a multicenter observational critical care study. Crit Care Med (2014) 1.42
Pharmacological aspects of albumin as a niche product in the intensive care unit. Crit Care Med (2005) 1.42
Metabolic effects of albumin therapy in acute lung injury measured by proton nuclear magnetic resonance spectroscopy of plasma: a pilot study. Crit Care Med (2011) 1.42
Rib fractures and death from deletion of osteoblast βcatenin in adult mice is rescued by corticosteroids. PLoS One (2013) 1.39
Myocyte-restricted focal adhesion kinase deletion attenuates pressure overload-induced hypertrophy. Circ Res (2006) 1.34
Body mass index is associated with reduced exhaled nitric oxide and higher exhaled 8-isoprostanes in asthmatics. Respir Res (2007) 1.33
Muscle ring finger 1 mediates cardiac atrophy in vivo. Am J Physiol Heart Circ Physiol (2009) 1.33
Cysteine redox potential determines pro-inflammatory IL-1beta levels. PLoS One (2009) 1.30
Mycobacterial lipoarabinomannans: modulators of dendritic cell function and the apoptotic response. Microbes Infect (2002) 1.29
Twist: a regulator of epithelial-mesenchymal transition in lung fibrosis. PLoS One (2009) 1.26
Selective ablation of matrix metalloproteinase-2 exacerbates experimental colitis: contrasting role of gelatinases in the pathogenesis of colitis. J Immunol (2006) 1.25
Predisposition for disrepair in the aged lung. Am J Med Sci (2012) 1.24
Atherosclerosis is attenuated by limiting superoxide generation in both macrophages and vessel wall cells. Arterioscler Thromb Vasc Biol (2007) 1.24
Lysophosphatidic acid receptors 1 and 2 play roles in regulation of vascular injury responses but not blood pressure. Circ Res (2008) 1.20
Characterization of a model to independently study regression of ventricular hypertrophy. J Surg Res (2007) 1.19
Regulatory T cell frequency and modulation of IFN-gamma and IL-17 in active and latent tuberculosis. Tuberculosis (Edinb) (2010) 1.19
The role of acute blood transfusion in the development of acute respiratory distress syndrome in patients with severe trauma. J Trauma (2005) 1.18
Development of a unique small molecule modulator of CXCR4. PLoS One (2012) 1.18
Oxidation of extracellular cysteine/cystine redox state in bleomycin-induced lung fibrosis. Am J Physiol Lung Cell Mol Physiol (2008) 1.18
Epidemiology of sepsis: recent advances. Curr Infect Dis Rep (2005) 1.17
Src family kinases mediate neutrophil adhesion to adherent platelets. Blood (2006) 1.16
Progression of pulmonary tuberculosis and efficiency of bacillus Calmette-Guérin vaccination are genetically controlled via a common sst1-mediated mechanism of innate immunity. J Immunol (2007) 1.14
Role of endoplasmic reticulum stress in age-related susceptibility to lung fibrosis. Am J Respir Cell Mol Biol (2012) 1.14
Use of senescence-accelerated mouse model in bleomycin-induced lung injury suggests that bone marrow-derived cells can alter the outcome of lung injury in aged mice. J Gerontol A Biol Sci Med Sci (2009) 1.13
The pathology of bleomycin-induced fibrosis is associated with loss of resident lung mesenchymal stem cells that regulate effector T-cell proliferation. Stem Cells (2011) 1.12
Activation of apoptosis, but not necrosis, during Mycobacterium tuberculosis infection correlated with decreased bacterial growth: role of TNF-alpha, IL-10, caspases and phospholipase A2. Cell Immunol (2007) 1.12
Oxidation of plasma cysteine/cystine redox state in endotoxin-induced lung injury. Am J Respir Cell Mol Biol (2008) 1.11
Mitochondrial oxidative stress in aortic stiffening with age: the role of smooth muscle cell function. Arterioscler Thromb Vasc Biol (2011) 1.11
FAK regulates cardiomyocyte survival following ischemia/reperfusion. J Mol Cell Cardiol (2008) 1.11
Abnormal lung aging in chronic obstructive pulmonary disease and idiopathic pulmonary fibrosis. Am J Respir Crit Care Med (2012) 1.10
Marital status and the epidemiology and outcomes of sepsis. Chest (2010) 1.09
Global utilization of low-dose corticosteroids in severe sepsis and septic shock: a report from the PROGRESS registry. Crit Care (2010) 1.09
Regression of pressure-induced left ventricular hypertrophy is characterized by a distinct gene expression profile. J Thorac Cardiovasc Surg (2009) 1.09
Dipyrimidine amines: a novel class of chemokine receptor type 4 antagonists with high specificity. J Med Chem (2010) 1.08
Healthcare disparities in critical illness. Crit Care Med (2013) 1.08
The role of body mass index and diabetes in the development of acute organ failure and subsequent mortality in an observational cohort. Crit Care (2006) 1.07
PINK1 deficiency impairs mitochondrial homeostasis and promotes lung fibrosis. J Clin Invest (2014) 1.06
Clinical review: Respiratory monitoring in the ICU - a consensus of 16. Crit Care (2012) 1.05
Thrombin and NAD(P)H oxidase-mediated regulation of CD44 and BMP4-Id pathway in VSMC, restenosis, and atherosclerosis. Circ Res (2006) 1.04
The host resistance locus sst1 controls innate immunity to Listeria monocytogenes infection in immunodeficient mice. J Immunol (2004) 1.04
CX3CR1 deficiency confers protection from intimal hyperplasia after arterial injury. Arterioscler Thromb Vasc Biol (2006) 1.04
FRNK expression promotes smooth muscle cell maturation during vascular development and after vascular injury. Arterioscler Thromb Vasc Biol (2008) 1.04
Increased frequency and cell death of CD16+ monocytes with Mycobacterium tuberculosis infection. Tuberculosis (Edinb) (2011) 1.01
Aging and lung injury repair: a role for bone marrow derived mesenchymal stem cells. J Cell Biochem (2008) 1.01
Metabolomics of bronchoalveolar lavage differentiate healthy HIV-1-infected subjects from controls. AIDS Res Hum Retroviruses (2014) 1.00
Protease-activated receptor 2 deficiency reduces cardiac ischemia/reperfusion injury. Arterioscler Thromb Vasc Biol (2010) 1.00
Nox activator 1: a potential target for modulation of vascular reactive oxygen species in atherosclerotic arteries. Circulation (2010) 1.00
Increased bleomycin-induced lung injury in mice deficient in the transcription factor T-bet. Am J Physiol Lung Cell Mol Physiol (2006) 0.99
Reduced EGFR causes abnormal valvular differentiation leading to calcific aortic stenosis and left ventricular hypertrophy in C57BL/6J but not 129S1/SvImJ mice. Am J Physiol Heart Circ Physiol (2009) 0.99
Influence of age on wound healing and fibrosis. J Pathol (2013) 0.98
Aging mesenchymal stem cells fail to protect because of impaired migration and antiinflammatory response. Am J Respir Crit Care Med (2014) 0.97
Functional profile of CD4+ and CD8+ T cells in latently infected individuals and patients with active TB. Tuberculosis (Edinb) (2013) 0.96
Airway and plasma leptin and adiponectin in lean and obese asthmatics and controls. J Asthma (2011) 0.96
Outcomes for critically ill patients with HIV and severe sepsis in the era of highly active antiretroviral therapy. J Crit Care (2011) 0.95
Vitamin D and sepsis: An emerging relationship. Dermatoendocrinol (2012) 0.95
Circulating endothelial progenitor cells inversely associate with organ dysfunction in sepsis. Intensive Care Med (2012) 0.95
Biomarkers in acute lung injury: are we making progress? Crit Care Med (2008) 0.95
Transient expression of FRNK reveals stage-specific requirement for focal adhesion kinase activity in cardiac growth. Circ Res (2009) 0.94
Vitamin D in sepsis: from basic science to clinical impact. Crit Care (2012) 0.94
Functional and phenotypic changes in monocytes from patients with tuberculosis are reversed with treatment. Microbes Infect (2006) 0.94
Activation of human mesenchymal stem cells impacts their therapeutic abilities in lung injury by increasing interleukin (IL)-10 and IL-1RN levels. Stem Cells Transl Med (2013) 0.93
Role of TLR2- and TLR4-mediated signaling in Mycobacterium tuberculosis-induced macrophage death. Cell Immunol (2010) 0.93
Inhibition of the CXCL12/CXCR4-axis as preventive therapy for radiation-induced pulmonary fibrosis. PLoS One (2013) 0.92
Differential induction of apoptosis and necrosis in monocytes from patients with tuberculosis and healthy control subjects. J Infect Dis (2004) 0.92
Pulmonary vs nonpulmonary sepsis and mortality in acute lung injury. Chest (2008) 0.92
Fluid management in acute respiratory distress syndrome. Curr Opin Crit Care (2013) 0.91
Alcohol abuse enhances pulmonary edema in acute respiratory distress syndrome. Alcohol Clin Exp Res (2009) 0.91
Attenuation of obliterative bronchiolitis by a CXCR4 antagonist in the murine heterotopic tracheal transplant model. J Heart Lung Transplant (2008) 0.91
Extending international sepsis epidemiology: the impact of organ dysfunction. Crit Care (2009) 0.91
Short women with severe sepsis-related acute lung injury receive lung protective ventilation less frequently: an observational cohort study. Crit Care (2011) 0.91