Published in J Immunol on June 01, 2008
Identification of a human helper T cell population that has abundant production of interleukin 22 and is distinct from T(H)-17, T(H)1 and T(H)2 cells. Nat Immunol (2009) 4.73
Targeting IL-17 and TH17 cells in chronic inflammation. Nat Rev Drug Discov (2012) 4.70
The cytokine network in asthma and chronic obstructive pulmonary disease. J Clin Invest (2008) 3.90
Retracted Interleukin 17 acts in synergy with B cell-activating factor to influence B cell biology and the pathophysiology of systemic lupus erythematosus. Nat Immunol (2009) 3.84
IL-17 is essential for host defense against cutaneous Staphylococcus aureus infection in mice. J Clin Invest (2010) 3.40
IL-17-producing human peripheral regulatory T cells retain suppressive function. Blood (2009) 3.04
Biology of interleukin-22. Semin Immunopathol (2010) 2.92
Circulating and gut-resident human Th17 cells express CD161 and promote intestinal inflammation. J Exp Med (2009) 2.82
Functions of T cells in asthma: more than just T(H)2 cells. Nat Rev Immunol (2010) 2.62
IL-17 as a future therapeutic target for rheumatoid arthritis. Nat Rev Rheumatol (2009) 2.18
IL-27 is a key regulator of IL-10 and IL-17 production by human CD4+ T cells. J Immunol (2009) 2.00
Effective narrow-band UVB radiation therapy suppresses the IL-23/IL-17 axis in normalized psoriasis plaques. J Invest Dermatol (2010) 1.84
In vivo activated monocytes from the site of inflammation in humans specifically promote Th17 responses. Proc Natl Acad Sci U S A (2009) 1.84
Elevated proinflammatory cytokine production by a skewed T cell compartment requires monocytes and promotes inflammation in type 2 diabetes. J Immunol (2010) 1.78
Translational mini-review series on Th17 cells: function and regulation of human T helper 17 cells in health and disease. Clin Exp Immunol (2009) 1.78
Expression of cytokines, chemokines and other effector molecules in two prototypic autoinflammatory skin diseases, pyoderma gangrenosum and Sweet's syndrome. Clin Exp Immunol (2014) 1.78
Mixed results with modulation of TH-17 cells in human autoimmune diseases. Nat Immunol (2009) 1.73
Th17 cells enhance viral persistence and inhibit T cell cytotoxicity in a model of chronic virus infection. J Exp Med (2009) 1.72
Association of pyoderma gangrenosum, acne, and suppurative hidradenitis (PASH) shares genetic and cytokine profiles with other autoinflammatory diseases. Medicine (Baltimore) (2014) 1.70
IL-26 is overexpressed in rheumatoid arthritis and induces proinflammatory cytokine production and Th17 cell generation. PLoS Biol (2012) 1.68
IL-17 regulates adipogenesis, glucose homeostasis, and obesity. J Immunol (2010) 1.67
CCR6 is required for IL-23-induced psoriasis-like inflammation in mice. J Clin Invest (2009) 1.65
From interleukin-23 to T-helper 17 cells: human T-helper cell differentiation revisited. Immunol Rev (2008) 1.65
Retracted Mast cells are the main interleukin 17-positive cells in anticitrullinated protein antibody-positive and -negative rheumatoid arthritis and osteoarthritis synovium. Arthritis Res Ther (2011) 1.65
Role of IL-17 and Th17 cells in liver diseases. Clin Dev Immunol (2010) 1.63
Increased frequency of dual-positive TH2/TH17 cells in bronchoalveolar lavage fluid characterizes a population of patients with severe asthma. J Allergy Clin Immunol (2014) 1.61
Interleukin-27: balancing protective and pathological immunity. Immunity (2012) 1.58
Regulating human Th17 cells via differential expression of IL-1 receptor. Blood (2009) 1.54
Identifying species of symbiont bacteria from the human gut that, alone, can induce intestinal Th17 cells in mice. Proc Natl Acad Sci U S A (2016) 1.50
Evidence for altered activity of the IL-6 pathway in chronic rhinosinusitis with nasal polyps. J Allergy Clin Immunol (2010) 1.42
Allergen uptake, activation, and IL-23 production by pulmonary myeloid DCs drives airway hyperresponsiveness in asthma-susceptible mice. PLoS One (2008) 1.38
Immunological abnormalities as potential biomarkers in Chronic Fatigue Syndrome/Myalgic Encephalomyelitis. J Transl Med (2011) 1.37
Translational mini-review series on Th17 cells: induction of interleukin-17 production by regulatory T cells. Clin Exp Immunol (2009) 1.37
Human asthma phenotypes: from the clinic, to cytokines, and back again. Immunol Rev (2011) 1.29
Characterization of intratumoral follicular helper T cells in follicular lymphoma: role in the survival of malignant B cells. Leukemia (2011) 1.29
Implication of Th17 and Th1 cells in patients with chronic active hepatitis B. J Clin Immunol (2009) 1.26
Identification of a cytokine network sustaining neutrophil and Th17 activation in untreated early rheumatoid arthritis. Arthritis Res Ther (2010) 1.25
Regulatory T-cell therapy for inflammatory bowel disease: more questions than answers. Immunology (2012) 1.20
Unlike Th1, Th17 cells mediate sustained autoimmune inflammation and are highly resistant to restimulation-induced cell death. J Immunol (2009) 1.19
Th17/Treg ratio in human graft-versus-host disease. Blood (2010) 1.19
Plasma IL-17A is increased in new-onset SLE patients and associated with disease activity. J Clin Immunol (2010) 1.15
Expression of Th-17 and RORγt mRNA in Behçet's Disease. Med Sci Monit (2011) 1.13
Role of inflammatory cells, cytokines and matrix metalloproteinases in neutrophil-mediated skin diseases. Clin Exp Immunol (2010) 1.12
Plasticity of T-cell phenotype and function: the T helper type 17 example. Immunology (2009) 1.11
Cutting edge: Type I IFN reverses human Th2 commitment and stability by suppressing GATA3. J Immunol (2010) 1.11
IL-17 contributes to cell-mediated defense against pulmonary Yersinia pestis infection. J Immunol (2010) 1.10
Psoriatic arthritis: from pathogenesis to therapy. Arthritis Res Ther (2009) 1.09
Translational mini-review series on Th17 cells: development of mouse and human T helper 17 cells. Clin Exp Immunol (2009) 1.05
Autoimmune hepatitis: new paradigms in the pathogenesis, diagnosis, and management. Hepatol Int (2010) 1.05
Interleukin-26: an IL-10-related cytokine produced by Th17 cells. Cytokine Growth Factor Rev (2010) 1.03
The effects of adalimumab and methotrexate treatment on peripheral Th17 cells and IL-17/IL-6 secretion in rheumatoid arthritis patients. Rheumatol Int (2009) 1.01
Evolving concepts in the pathogenesis of NASH: beyond steatosis and inflammation. Int J Mol Sci (2014) 1.00
Superantigenic Staphylococcus aureus stimulates production of interleukin-17 from memory but not naive T cells. Infect Immun (2009) 0.98
Rheumatoid arthritis pathophysiology: update on emerging cytokine and cytokine-associated cell targets. Rheumatology (Oxford) (2014) 0.98
Cytokine mediators of Th17 function. Eur J Immunol (2009) 0.97
TNF-α blockade induces IL-10 expression in human CD4+ T cells. Nat Commun (2014) 0.96
Histologic eosinophilic gastritis is a systemic disorder associated with blood and extragastric eosinophilia, TH2 immunity, and a unique gastric transcriptome. J Allergy Clin Immunol (2014) 0.96
IL-23 receptor regulation by Let-7f in human CD4+ memory T cells. J Immunol (2011) 0.96
IL-17-producing peripheral blood CD177+ neutrophils increase in allergic asthmatic subjects. Allergy Asthma Clin Immunol (2013) 0.96
The distribution of immunomodulatory cells in the lungs of patients with idiopathic pulmonary fibrosis. Mod Pathol (2011) 0.96
CBP30, a selective CBP/p300 bromodomain inhibitor, suppresses human Th17 responses. Proc Natl Acad Sci U S A (2015) 0.95
Cellular mediators of inflammation: tregs and TH17 cells in gastrointestinal diseases. Mediators Inflamm (2010) 0.94
Angels and demons: Th17 cells represent a beneficial response, while neutrophil IL-17 is associated with poor prognosis in squamous cervical cancer. Oncoimmunology (2015) 0.94
Frequency of Th17 CD4+ T cells in early rheumatoid arthritis: a marker of anti-CCP seropositivity. PLoS One (2012) 0.93
The Interplay Between Monocytes/Macrophages and CD4(+) T Cell Subsets in Rheumatoid Arthritis. Front Immunol (2015) 0.92
Nutritional protective mechanisms against gut inflammation. J Nutr Biochem (2013) 0.92
Keratinocytes under Fire of Proinflammatory Cytokines: Bona Fide Innate Immune Cells Involved in the Physiopathology of Chronic Atopic Dermatitis and Psoriasis. J Allergy (Cairo) (2012) 0.91
Cytokine profiles in asthma families depend on age and phenotype. PLoS One (2010) 0.90
Immune regulation of bone loss by Th17 cells. Arthritis Res Ther (2008) 0.90
miR-155 deficiency protects mice from experimental colitis by reducing T helper type 1/type 17 responses. Immunology (2014) 0.90
IL-17 inhibits chondrogenic differentiation of human mesenchymal stem cells. PLoS One (2013) 0.89
Harnessing regulatory T cells to suppress asthma: from potential to therapy. Am J Respir Cell Mol Biol (2010) 0.89
CCR6 as a possible therapeutic target in psoriasis. Expert Opin Ther Targets (2010) 0.88
The E3 ubiquitin ligase adaptor Ndfip1 regulates Th17 differentiation by limiting the production of proinflammatory cytokines. J Immunol (2012) 0.88
Dendritic cells a double-edge sword in autoimmune responses. Front Immunol (2012) 0.87
Differential mucosal expression of Th17-related genes between the inflamed colon and ileum of patients with inflammatory bowel disease. BMC Immunol (2010) 0.87
The ratio of Treg/Th17 cells correlates with the disease activity of primary immune thrombocytopenia. PLoS One (2012) 0.87
Response of peripheral blood Th17 cells to inhaled Dermatophagoides pteronyssinus in patients with allergic rhinitis and asthma. Lung (2012) 0.86
CCL20 Secretion from the Nucleus Pulposus Improves the Recruitment of CCR6-Expressing Th17 Cells to Degenerated IVD Tissues. PLoS One (2013) 0.85
Fatigue-enhanced hyperalgesia in response to muscle insult: induction and development occur in a sex-dependent manner. Pain (2013) 0.85
The Role of Th17 in Neuroimmune Disorders: Target for CAM Therapy. Part I. Evid Based Complement Alternat Med (2011) 0.85
Optimizing dendritic cell-based approaches for cancer immunotherapy. Yale J Biol Med (2014) 0.85
Potential involvement of IL-17F in asthma. J Immunol Res (2014) 0.85
The other T helper cells in asthma pathogenesis. J Allergy (Cairo) (2010) 0.84
IL-8, IL-10, TGF-β, and GCSF levels were increased in severe persistent allergic asthma patients with the anti-IgE treatment. Mediators Inflamm (2012) 0.84
Immunomodulation Mechanism of Antidepressants: Interactions between Serotonin/Norepinephrine Balance and Th1/Th2 Balance. Curr Neuropharmacol (2012) 0.83
Halofuginone-induced amino acid starvation regulates Stat3-dependent Th17 effector function and reduces established autoimmune inflammation. J Immunol (2014) 0.83
Molecular targets in the treatment of alcoholic hepatitis. World J Gastroenterol (2012) 0.82
Cell biology of osteoimmunology. Wien Med Wochenschr (2010) 0.82
IL-23 induces atopic dermatitis-like inflammation instead of psoriasis-like inflammation in CCR2-deficient mice. PLoS One (2013) 0.81
Cytokines in chronic respiratory diseases. F1000 Biol Rep (2013) 0.81
IL-17F Induces CCL20 in Bronchial Epithelial Cells. J Allergy (Cairo) (2011) 0.81
Mesenchymal Stem Cells of Dental Origin-Their Potential for Antiinflammatory and Regenerative Actions in Brain and Gut Damage. Curr Neuropharmacol (2016) 0.81
Lineage-specific adjacent IFNG and IL26 genes share a common distal enhancer element. Genes Immun (2012) 0.81
Plasmin plays an essential role in amplification of psoriasiform skin inflammation in mice. PLoS One (2011) 0.80
Acid-Sensitive Sheddable PEGylated PLGA Nanoparticles Increase the Delivery of TNF-α siRNA in Chronic Inflammation Sites. Mol Ther Nucleic Acids (2016) 0.80
Production of CCL20 on nucleus pulposus cells recruits IL-17-producing cells to degenerated IVD tissues in rat models. J Mol Histol (2015) 0.79
Predominance of activated, clonally expanded T helper type 17 cells within the CD4+ T cell population in psoriatic lesions. Clin Exp Immunol (2013) 0.79
IL-17A-mediated sRANK ligand elevation involved in postmenopausal osteoporosis. Osteoporos Int (2013) 0.79
Binding of the Drosophila cytokine Spätzle to Toll is direct and establishes signaling. Nat Immunol (2003) 2.99
The humoral pattern recognition receptor PTX3 is stored in neutrophil granules and localizes in extracellular traps. J Exp Med (2007) 2.71
Direct stimulation of human T cells via TLR5 and TLR7/8: flagellin and R-848 up-regulate proliferation and IFN-gamma production by memory CD4+ T cells. J Immunol (2005) 2.67
Mesenchymal stem cells inhibit human Th17 cell differentiation and function and induce a T regulatory cell phenotype. J Immunol (2010) 2.27
Cutting edge: IL-21 is a switch factor for the production of IgG1 and IgG3 by human B cells. J Immunol (2004) 2.04
Mesenchymal stem cells: innovative therapeutic tools for rheumatic diseases. Nat Rev Rheumatol (2009) 1.88
Tumor-associated leukemia inhibitory factor and IL-6 skew monocyte differentiation into tumor-associated macrophage-like cells. Blood (2007) 1.83
IL-26 is overexpressed in rheumatoid arthritis and induces proinflammatory cytokine production and Th17 cell generation. PLoS Biol (2012) 1.68
Neutrophils efficiently cross-prime naive T cells in vivo. Blood (2007) 1.67
Telomerase levels control the lifespan of human T lymphocytes. Blood (2003) 1.59
Multiparameter grouping delineates heterogeneous populations of human IL-17 and/or IL-22 T-cell producers that share antigen specificities with other T-cell subsets. Eur J Immunol (2011) 1.59
Target-dependent specification of the neurotransmitter phenotype: cholinergic differentiation of sympathetic neurons is mediated in vivo by gp 130 signaling. Development (2005) 1.44
TLR4-mediated skin carcinogenesis is dependent on immune and radioresistant cells. EMBO J (2010) 1.37
Oncostatin M secreted by skin infiltrating T lymphocytes is a potent keratinocyte activator involved in skin inflammation. J Immunol (2007) 1.36
Interleukin-33 overexpression is associated with liver fibrosis in mice and humans. J Cell Mol Med (2009) 1.36
Neuropoietin, a new IL-6-related cytokine signaling through the ciliary neurotrophic factor receptor. Proc Natl Acad Sci U S A (2004) 1.36
IL-22 participates in an innate anti-HIV-1 host-resistance network through acute-phase protein induction. J Immunol (2007) 1.35
Lipid composition of membranes of Escherichia coli by liquid chromatography/tandem mass spectrometry using negative electrospray ionization. Rapid Commun Mass Spectrom (2007) 1.30
Induction of a peptide with activity against a broad spectrum of pathogens in the Aedes aegypti salivary gland, following Infection with Dengue Virus. PLoS Pathog (2011) 1.30
A Fluorospot assay to detect single T lymphocytes simultaneously producing multiple cytokines. J Immunol Methods (2003) 1.29
Induction of osteogenesis in mesenchymal stem cells by activated monocytes/macrophages depends on oncostatin M signaling. Stem Cells (2012) 1.29
Dengue-virus-infected dendritic cells trigger vascular leakage through metalloproteinase overproduction. EMBO Rep (2006) 1.24
Functional interaction of STAT3 transcription factor with the coactivator NcoA/SRC1a. J Biol Chem (2001) 1.20
Ectopic hTERT expression extends the life span of human CD4+ helper and regulatory T-cell clones and confers resistance to oxidative stress-induced apoptosis. Blood (2003) 1.17
Activated, but not resting human Th2 cells, in contrast to Th1 and T regulatory cells, produce soluble ST2 and express low levels of ST2L at the cell surface. Eur J Immunol (2002) 1.12
Full virulence of Pseudomonas aeruginosa requires OprF. Infect Immun (2010) 1.12
Expression of recombinant proteins in a lipid A mutant of Escherichia coli BL21 with a strongly reduced capacity to induce dendritic cell activation and maturation. J Immunol Methods (2003) 1.10
Involvement of N-acylhomoserine lactones throughout plant infection by Erwinia carotovora subsp. atroseptica (Pectobacterium atrosepticum). Mol Plant Microbe Interact (2004) 1.09
IL-34 induces the differentiation of human monocytes into immunosuppressive macrophages. antagonistic effects of GM-CSF and IFNγ. PLoS One (2013) 1.09
CCL20 and β-defensin-2 induce arrest of human Th17 cells on inflamed endothelium in vitro under flow conditions. J Immunol (2010) 1.06
Inactivation of cardiotrophin-like cytokine, a second ligand for ciliary neurotrophic factor receptor, leads to cold-induced sweating syndrome in a patient. Proc Natl Acad Sci U S A (2006) 1.05
Predominant expression of the long isoform of GP130-like (GPL) receptor is required for interleukin-31 signaling. Eur Cytokine Netw (2005) 1.04
Escape from p21-mediated oncogene-induced senescence leads to cell dedifferentiation and dependence on anti-apoptotic Bcl-xL and MCL1 proteins. J Biol Chem (2011) 1.02
The sigma factor AlgU plays a key role in formation of robust biofilms by nonmucoid Pseudomonas aeruginosa. J Bacteriol (2010) 1.02
GPL, a novel cytokine receptor related to GP130 and leukemia inhibitory factor receptor. J Biol Chem (2003) 1.02
Dengue virus replication in infected human keratinocytes leads to activation of antiviral innate immune responses. Infect Genet Evol (2011) 1.01
Novel role of Janus kinase 1 in the regulation of oncostatin M receptor surface expression. J Biol Chem (2002) 1.01
Identification and relative quantification of fatty acids in Escherichia coli membranes by gas chromatography/mass spectrometry. Rapid Commun Mass Spectrom (2007) 0.98
Regulation of the cytotoxic effects of Pseudomonas fluorescens by growth temperature. Res Microbiol (2004) 0.97
Characterization and enumeration of cells secreting tumor markers in the peripheral blood of breast cancer patients. J Immunol Methods (2005) 0.97
Secretion of IL-6, IL-11 and LIF by human cardiomyocytes in primary culture. Cytokine (2002) 0.96
Thermoregulation of N-acyl homoserine lactone-based quorum sensing in the soft rot bacterium Pectobacterium atrosepticum. Appl Environ Microbiol (2007) 0.94
IFN-gamma-mediated inhibition of human IgE synthesis by IL-21 is associated with a polymorphism in the IL-21R gene. J Immunol (2006) 0.94
Lipoproteins of Enterococcus faecalis: bioinformatic identification, expression analysis and relation to virulence. Microbiology (2011) 0.94
IL-22, in contrast to IL-10, does not induce Ig production, due to absence of a functional IL-22 receptor on activated human B cells. Int Immunol (2002) 0.94
Aedes aegypti saliva enhances dengue virus infection of human keratinocytes by suppressing innate immune responses. J Invest Dermatol (2012) 0.93
Soluble HIV-1 gp120 enhances HIV-1 replication in non-dividing CD4+ T cells, mediated via cell signaling and Tat cofactor overexpression. AIDS (2005) 0.93
Deciphering the function of the outer membrane protein OprD homologue of Acinetobacter baumannii. Antimicrob Agents Chemother (2012) 0.93
Gram-negative bacterial sensors for eukaryotic signal molecules. Sensors (Basel) (2009) 0.93
Pore size dependence on growth temperature is a common characteristic of the major outer membrane protein OprF in psychrotrophic and mesophilic Pseudomonas species. Appl Environ Microbiol (2004) 0.92
Activated and resting regulatory T cell exhaustion concurs with high levels of interleukin-22 expression in systemic sclerosis lesions. Ann Rheum Dis (2012) 0.92
Pulmonary CCL18 recruits human regulatory T cells. J Immunol (2012) 0.90
GammaH2AX, an accurate marker that analyzes UV genotoxic effects on human keratinocytes and on human skin. Photochem Photobiol (2010) 0.90
Cytotoxic effects of the lipopolysaccharide from Pseudomonas fluorescens on neurons and glial cells. Microb Pathog (2003) 0.90
Enhanced frequency of CD18- and CD49b-expressing T cells in peripheral blood of asthmatic patients correlates with disease severity. Int Arch Allergy Immunol (2006) 0.90
Leukemia inhibitory factor (LIF), cardiotrophin-1, and oncostatin M share structural binding determinants in the immunoglobulin-like domain of LIF receptor. J Biol Chem (2003) 0.89
Effect of GABA, a bacterial metabolite, on Pseudomonas fluorescens surface properties and cytotoxicity. Int J Mol Sci (2013) 0.88
Contrasting effect of exercise and angiotensin II hypertension on in vivo and in vitro cardiac angiogenesis in rats. Am J Physiol Regul Integr Comp Physiol (2008) 0.88
Definition and characterization of an inhibitor for interleukin-31. J Biol Chem (2010) 0.88
Thermodependence of growth and enzymatic activities implicated in pathogenicity of two Erwinia carotovora subspecies (Pectobacterium spp.). Can J Microbiol (2004) 0.88
Molecular and functional characterization of a soluble form of oncostatin M/interleukin-31 shared receptor. J Biol Chem (2006) 0.88
Knocking down Cav1 calcium channels implicated in Th2 cell activation prevents experimental asthma. Am J Respir Crit Care Med (2010) 0.88
Polarized Th2 like cells, in the absence of Th0 cells, are responsible for lymphocyte produced IL-4 in high IgE-producer schistosomiasis patients. BMC Immunol (2002) 0.88
Two different contact sites are recruited by cardiotrophin-like cytokine (CLC) to generate the CLC/CLF and CLC/sCNTFRalpha composite cytokines. J Biol Chem (2004) 0.87
Outer membrane modifications of Pseudomonas fluorescens MF37 in response to hyperosmolarity. J Proteome Res (2008) 0.87
Nicotinamide phosphoribosyltransferase/visfatin expression by inflammatory monocytes mediates arthritis pathogenesis. Ann Rheum Dis (2013) 0.86
Behaviors of keratinocytes and fibroblasts on films of PLA50-PEO-PLA50 triblock copolymers with various PLA segment lengths. J Mater Sci Mater Med (2007) 0.86
Transcription of the oprF gene of Pseudomonas aeruginosa is dependent mainly on the SigX sigma factor and is sucrose induced. J Bacteriol (2012) 0.86
Detection of peripheral HIV-1-specific memory B cells in patients untreated or receiving highly active antiretroviral therapy. AIDS (2003) 0.86
Invariant NKT cells drive hepatic cytokinic microenvironment favoring efficient granuloma formation and early control of Leishmania donovani infection. PLoS One (2012) 0.86
The prolipoprotein diacylglyceryl transferase (Lgt) of Enterococcus faecalis contributes to virulence. Microbiology (2011) 0.86
IL-27 structural analysis demonstrates similarities with ciliary neurotrophic factor (CNTF) and leads to the identification of antagonistic variants. Proc Natl Acad Sci U S A (2010) 0.86
Irinotecan induces steroid and xenobiotic receptor (SXR) signaling to detoxification pathway in colon cancer cells. Mol Cancer (2011) 0.84
Involvement of peptidylprolyl cis/trans isomerases in Enterococcus faecalis virulence. Infect Immun (2012) 0.84
Neonatal and adult microglia cross-present exogenous antigens. Glia (2008) 0.84