Published in Biogerontology on July 25, 2008
Hydrogen peroxide fuels aging, inflammation, cancer metabolism and metastasis: the seed and soil also needs "fertilizer". Cell Cycle (2011) 1.36
Comparison of proteomic and transcriptomic profiles in the bronchial airway epithelium of current and never smokers. PLoS One (2009) 1.16
An integrated proteomics analysis of bone tissues in response to mechanical stimulation. BMC Syst Biol (2011) 0.82
Oxidative stress in aging: advances in proteomic approaches. Oxid Med Cell Longev (2014) 0.81
An approach to correlate tandem mass spectral data of peptides with amino acid sequences in a protein database. J Am Soc Mass Spectrom (1994) 45.51
Large-scale analysis of the yeast proteome by multidimensional protein identification technology. Nat Biotechnol (2001) 28.01
The serial cultivation of human diploid cell strains. Exp Cell Res (1961) 25.11
Cellular senescence: when bad things happen to good cells. Nat Rev Mol Cell Biol (2007) 16.55
Direct analysis of protein complexes using mass spectrometry. Nat Biotechnol (1999) 12.42
DTASelect and Contrast: tools for assembling and comparing protein identifications from shotgun proteomics. J Proteome Res (2003) 12.31
Translational control in stress and apoptosis. Nat Rev Mol Cell Biol (2005) 8.91
Gene expression profile of aging and its retardation by caloric restriction. Science (1999) 8.06
Physiological functions of thioredoxin and thioredoxin reductase. Eur J Biochem (2000) 7.25
An automated multidimensional protein identification technology for shotgun proteomics. Anal Chem (2001) 6.90
Molecular mechanisms of translational control. Nat Rev Mol Cell Biol (2004) 6.39
Microarray analysis of replicative senescence. Curr Biol (1999) 4.25
Antioxidant and redox regulation of gene transcription. FASEB J (1996) 4.09
Thioredoxin reductase. Biochem J (2000) 3.47
AP-1 transcriptional activity is regulated by a direct association between thioredoxin and Ref-1. Proc Natl Acad Sci U S A (1997) 3.21
Fibroblasts regulate the switch from acute resolving to chronic persistent inflammation. Trends Immunol (2001) 3.08
Proteomic analysis by multidimensional protein identification technology. Methods Mol Biol (2006) 2.69
Distinct effects of thioredoxin and antioxidants on the activation of transcription factors NF-kappa B and AP-1. Proc Natl Acad Sci U S A (1994) 2.62
Regulation of metallothionein gene expression by oxidative stress and metal ions. Biochem Pharmacol (2000) 2.59
Senescence-like growth arrest induced by hydrogen peroxide in human diploid fibroblast F65 cells. Proc Natl Acad Sci U S A (1994) 2.55
Fibroblasts as sentinel cells. Synthesis of chemokines and regulation of inflammation. Am J Pathol (1997) 2.47
Cap-dependent and cap-independent translation in eukaryotic systems. Gene (2004) 2.05
Starting the protein synthesis machine: eukaryotic translation initiation. Bioessays (2003) 2.00
Oxygen free radicals and metallothionein. Free Radic Biol Med (1993) 1.84
Large scale protein profiling by combination of protein fractionation and multidimensional protein identification technology (MudPIT). Mol Cell Proteomics (2005) 1.71
Replicative senescence: a critical review. Mech Ageing Dev (2004) 1.66
Thioredoxin reductase as a pathophysiological factor and drug target. Eur J Biochem (2000) 1.63
Proteomic characterization of wheat amyloplasts using identification of proteins by tandem mass spectrometry. Proteomics (2002) 1.60
Thioredoxin nuclear translocation and interaction with redox factor-1 activates the activator protein-1 transcription factor in response to ionizing radiation. Cancer Res (2000) 1.48
Oxidative stress induced heat shock factor phosphorylation and HSF-dependent activation of yeast metallothionein gene transcription. Genes Dev (1996) 1.41
Transcriptional induction of the mouse metallothionein-I gene in hydrogen peroxide-treated Hepa cells involves a composite major late transcription factor/antioxidant response element and metal response promoter elements. Nucleic Acids Res (1994) 1.35
Uncoupling the senescent phenotype from telomere shortening in hydrogen peroxide-treated fibroblasts. Exp Cell Res (2001) 1.35
Apoptosis or senescence-like growth arrest: influence of cell-cycle position, p53, p21 and bax in H2O2 response of normal human fibroblasts. Biochem J (2000) 1.35
Replicative senescence and oxidant-induced premature senescence. Beyond the control of cell cycle checkpoints. Ann N Y Acad Sci (2000) 1.29
Thioredoxin reductase regulates AP-1 activity as well as thioredoxin nuclear localization via active cysteines in response to ionizing radiation. Oncogene (2002) 1.18
Multidimensional protein identification technology (MudPIT): technical overview of a profiling method optimized for the comprehensive proteomic investigation of normal and diseased heart tissue. J Am Soc Mass Spectrom (2005) 1.13
Metallothionein redox cycle and function. Exp Biol Med (Maywood) (2006) 1.09
Identification of proteins released by pancreatic cancer cells by multidimensional protein identification technology: a strategy for identification of novel cancer markers. FASEB J (2005) 1.09
c-Fos phosphorylation induced by H2O2 prevents proteasomal degradation of c-Fos in cardiomyocytes. J Biol Chem (2004) 1.04
Development and molecular characterization of HCT-116 cell lines resistant to the tumor promoter and multiple stress-inducer, deoxycholate. Carcinogenesis (2002) 1.02
Induction of antioxidant and detoxification response by oxidants in cardiomyocytes: evidence from gene expression profiling and activation of Nrf2 transcription factor. J Mol Cell Cardiol (2006) 1.01
cDNA microarray analysis of multidrug resistance: doxorubicin selection produces multiple defects in apoptosis signaling pathways. J Pharmacol Exp Ther (2001) 0.99
Involvement of Rb family proteins, focal adhesion proteins and protein synthesis in senescent morphogenesis induced by hydrogen peroxide. J Cell Sci (2000) 0.92
Proteomic identification of insulin-like growth factor-binding protein-6 induced by sublethal H2O2 stress from human diploid fibroblasts. Mol Cell Proteomics (2005) 0.91
Principles and applications of multidimensional protein identification technology. Expert Rev Proteomics (2004) 0.86
Gene expression and regulation in H2O2-induced premature senescence of human foreskin fibroblasts expressing or not telomerase. Exp Gerontol (2004) 0.86
Measurements of hydrogen peroxide induced premature senescence: senescence-associated beta-galactosidase and DNA synthesis index in human diploid fibroblasts with down-regulated p53 or Rb. Biogerontology (2000) 0.86
Heme oxygenase-1 and interleukin-11 are overexpressed in stress-induced premature senescence of human WI-38 fibroblasts induced by tert-butylhydroperoxide and ethanol. Biogerontology (2007) 0.82
Expression of metallothionein isoforms in human chorioretinal complex. Curr Eye Res (2002) 0.81
Two-dimensional nanoflow liquid chromatography-tandem mass spectrometry of proteins extracted from rice leaves and roots. Methods Mol Biol (2007) 0.76
Penetration of the stigma and style elicits a novel transcriptome in pollen tubes, pointing to genes critical for growth in a pistil. PLoS Genet (2009) 2.83
Cystatin C increases in cardiac injury: a role in extracellular matrix protein modulation. Cardiovasc Res (2010) 1.64
Comparative analysis of SET domain proteins in maize and Arabidopsis reveals multiple duplications preceding the divergence of monocots and dicots. Plant Physiol (2003) 1.47
Proteomic identification of ubiquitinated proteins from human cells expressing His-tagged ubiquitin. Proteomics (2005) 1.37
Translational control of nrf2 protein in activation of antioxidant response by oxidants. Mol Pharmacol (2007) 1.37
Methylation of FEN1 suppresses nearby phosphorylation and facilitates PCNA binding. Nat Chem Biol (2010) 1.29
Extracellular proteins in pea root tip and border cell exudates. Plant Physiol (2006) 1.27
Media ion composition controls regulatory and virulence response of Salmonella in spaceflight. PLoS One (2008) 1.19
Identification and characterization of a diamine exporter in colon epithelial cells. J Biol Chem (2008) 1.12
Transcriptional and proteomic responses of Pseudomonas aeruginosa PAO1 to spaceflight conditions involve Hfq regulation and reveal a role for oxygen. Appl Environ Microbiol (2010) 1.12
Signals of oxidant-induced cardiomyocyte hypertrophy: key activation of p70 S6 kinase-1 and phosphoinositide 3-kinase. J Pharmacol Exp Ther (2002) 1.08
Pulmonary biomarkers based on alterations in protein expression after exposure to arsenic. Environ Health Perspect (2007) 1.08
The multifunctional Ca(2+)/calmodulin-dependent protein kinase II delta (CaMKIIδ) phosphorylates cardiac titin's spring elements. J Mol Cell Cardiol (2012) 1.06
Nucleolin stabilizes Bcl-X L messenger RNA in response to UVA irradiation. Cancer Res (2008) 1.05
Novel mechanisms of sublethal oxidant toxicity: induction of premature senescence in human fibroblasts confers tumor promoter activity. Exp Cell Res (2003) 1.04
c-Fos phosphorylation induced by H2O2 prevents proteasomal degradation of c-Fos in cardiomyocytes. J Biol Chem (2004) 1.04
Induction of antioxidant and detoxification response by oxidants in cardiomyocytes: evidence from gene expression profiling and activation of Nrf2 transcription factor. J Mol Cell Cardiol (2006) 1.01
Control costs, enhance quality, and increase revenue in three top general public hospitals in Beijing, China. PLoS One (2013) 0.96
Epidermal growth factor receptor-dependent and -independent pathways in hydrogen peroxide-induced mitogen-activated protein kinase activation in cardiomyocytes and heart fibroblasts. J Pharmacol Exp Ther (2004) 0.95
Inhibition of apoptosis by progesterone in cardiomyocytes. Aging Cell (2010) 0.95
Snacking is associated with overall diet quality among adults. J Acad Nutr Diet (2012) 0.91
Improved MALDI-TOF imaging yields increased protein signals at high molecular mass. J Am Soc Mass Spectrom (2008) 0.91
Linking oxidative stress and genetics of aging with p66Shc signaling and forkhead transcription factors. Biogerontology (2003) 0.91
Proteomic identification of insulin-like growth factor-binding protein-6 induced by sublethal H2O2 stress from human diploid fibroblasts. Mol Cell Proteomics (2005) 0.91
P38 MAPK mediates COX-2 gene expression by corticosterone in cardiomyocytes. Cell Signal (2008) 0.90
La autoantigen mediates oxidant induced de novo Nrf2 protein translation. Mol Cell Proteomics (2011) 0.90
Interleukin 6 mediates the therapeutic effects of adipose-derived stromal/stem cells in lipopolysaccharide-induced acute lung injury. Stem Cells (2014) 0.90
Engineering of N. benthamiana L. plants for production of N-acetylgalactosamine-glycosylated proteins--towards development of a plant-based platform for production of protein therapeutics with mucin type O-glycosylation. BMC Biotechnol (2010) 0.90
Regioselective glucuronidation of flavonols by six human UGT1A isoforms. Pharm Res (2011) 0.89
Corticosteroids induce COX-2 expression in cardiomyocytes: role of glucocorticoid receptor and C/EBP-beta. Am J Physiol Cell Physiol (2008) 0.89
p66(Shc): at the crossroad of oxidative stress and the genetics of aging. Trends Mol Med (2003) 0.88
UDP-glucuronosyltransferase (UGT) 1A9-overexpressing HeLa cells is an appropriate tool to delineate the kinetic interplay between breast cancer resistance protein (BRCP) and UGT and to rapidly identify the glucuronide substrates of BCRP. Drug Metab Dispos (2011) 0.88
Dexamethasone induces transcriptional activation of Bcl-xL gene and inhibits cardiac injury by myocardial ischemia. Eur J Pharmacol (2011) 0.88
Lanthanide doped nanoparticles as remote sensors for magnetic fields. Nanoscale (2014) 0.86
Association between winter season and risk of death from cardiovascular diseases: a study in more than half a million inpatients in Beijing, China. BMC Cardiovasc Disord (2013) 0.85
Involvement of oxidants and AP-1 in angiotensin II-activated NFAT3 transcription factor. Am J Physiol Cell Physiol (2006) 0.84
Corticosteroids induce cyclooxygenase 1 expression in cardiomyocytes: role of glucocorticoid receptor and Sp3 transcription factor. Mol Endocrinol (2008) 0.83
Human laminin-5 and laminin-10 mediated gene expression of prostate carcinoma cells. Prostate (2006) 0.83
Gene expression analysis of HCT116 colon tumor-derived cells treated with the polyamine analog PG-11047. Cancer Genomics Proteomics (2009) 0.83
Partial proteasome inhibition in human fibroblasts triggers accelerated M1 senescence or M2 crisis depending on p53 and Rb status. Aging Cell (2008) 0.83
Distinct roles of p42/p44(ERK) and p38 MAPK in oxidant-induced AP-1 activation and cardiomyocyte hypertrophy. Cardiovasc Toxicol (2003) 0.83
NAD(P)H:quinone oxidoreductase 1 is induced by progesterone in cardiomyocytes. Cardiovasc Toxicol (2012) 0.83
Pilot study on the effects of dietary conjugated linoleic acid on tumorigenesis and gene expression in PyMT transgenic mice. Carcinogenesis (2010) 0.82
FP prostanoid receptor-mediated induction of the expression of early growth response factor-1 by activation of a Ras/Raf/mitogen-activated protein kinase signaling cascade. Mol Pharmacol (2007) 0.82
Interactions of sodium selenite, glutathione, arsenic species, and omega class human glutathione transferase. Chem Res Toxicol (2005) 0.81
Spatially and temporally regulated alpha6 integrin cleavage during Xenopus laevis development. Biochem Biophys Res Commun (2007) 0.81
Inhibitors of GSK-3 prevent corticosterone from inducing COX-1 expression in cardiomyocytes. Cardiovasc Toxicol (2008) 0.81
Structure elucidation of two triterpenoid saponins from rhizome of Anemone raddeana Regel. Fitoterapia (2009) 0.80
An organic approach for nanostructured multiferroics. Nanoscale (2015) 0.79
New site(s) of methylglyoxal-modified human serum albumin, identified by multiple reaction monitoring, alter warfarin binding and prostaglandin metabolism. Chem Biol Interact (2010) 0.79
LY294002 inhibits glucocorticoid-induced COX-2 gene expression in cardiomyocytes through a phosphatidylinositol 3 kinase-independent mechanism. Toxicol Appl Pharmacol (2008) 0.79
Evaluation of a hypoxia regulated gene panel in ovarian cancer. Cancer Microenviron (2015) 0.78
Using bioinformatics and genome analysis for new therapeutic interventions. Mol Cancer Ther (2005) 0.78
Expression of glucocorticoid-induced leucine zipper (GILZ) in cardiomyocytes. Cardiovasc Toxicol (2013) 0.78
Androgen regulation of the human FERM domain encoding gene EHM2 in a cell model of steroid-induced differentiation. Biochem Biophys Res Commun (2003) 0.78
Using logistic regression to improve the prognostic value of microarray gene expression data sets: application to early-stage squamous cell carcinoma of the lung and triple negative breast carcinoma. BMC Med Genomics (2014) 0.78
Arsenic alters vascular smooth muscle cell focal adhesion complexes leading to activation of FAK-src mediated pathways. Toxicol Appl Pharmacol (2008) 0.77
Synthesis and characterization of copper(ii) complexes with multidentate ligands as catalysts for the direct hydroxylation of benzene to phenol. Dalton Trans (2015) 0.77
p21(WAF1/Cip1/Sdi1) knockout mice respond to doxorubicin with reduced cardiotoxicity. Toxicol Appl Pharmacol (2011) 0.77
Photoluminescence from Bi5(GaCl4)3 molecular crystal. Dalton Trans (2012) 0.76
The suppressor of AAC2 Lethality SAL1 modulates sensitivity of heterologously expressed artemia ADP/ATP carrier to bongkrekate in yeast. PLoS One (2013) 0.76
Correction: Penetration of the Stigma and Style Elicits a Novel Transcriptome in Pollen Tubes, Pointing to Genes Critical for Growth in a Pistil. PLoS Genet (2016) 0.75
Dodecafluoropentane emulsion elicits cardiac protection against myocardial infarction through an ATP-Sensitive K+ channel dependent mechanism. Cardiovasc Drugs Ther (2014) 0.75
Modern medicine and the Garden of Eden. Am J Med (2012) 0.75
Histone deacetylase 6 associates with ribosomes and regulates de novo protein translation during arsenite stress. Toxicol Sci (2012) 0.75
Northern blot analysis for expression profiling of mRNAs and small RNAs. Methods Mol Biol (2012) 0.75
Peptide and non-peptide mimetics utilize different pathways for signal transduction. Adv Exp Med Biol (2009) 0.75
Enhanced broadband excited upconversion luminescence in Ho-doped glasses by codoping with bismuth. Opt Lett (2014) 0.75
So, you want to live to 120? The genie in the bottle. Am J Med (2012) 0.75
Has the genomic revolution failed? Clin Cardiol (2012) 0.75
Regulation of structure rigidity for improvement of the thermal stability of near-infrared luminescence in Bi-doped borate glasses. Opt Express (2013) 0.75
Surface passivated silicon nanocrystals with stable luminescence synthesized by femtosecond laser ablation in solution. Phys Chem Chem Phys (2011) 0.75
Origin of structural relaxation dependent spectroscopic features of bismuth-activated glasses. Opt Express (2014) 0.75