Published in Cell on July 25, 2008
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A chemical biology approach reveals period shortening of the mammalian circadian clock by specific inhibition of GSK-3beta. Proc Natl Acad Sci U S A (2008) 2.39
Metabolism control by the circadian clock and vice versa. Nat Struct Mol Biol (2009) 1.99
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Circadian glucose homeostasis requires compensatory interference between brain and liver clocks. Proc Natl Acad Sci U S A (2008) 0.81
Molecular clocks in pharmacology. Handb Exp Pharmacol (2013) 0.80
Lipids around the Clock: Focus on Circadian Rhythms and Lipid Metabolism. Biology (Basel) (2015) 0.80
Comparative Circadian Metabolomics Reveal Differential Effects of Nutritional Challenge in the Serum and Liver. J Biol Chem (2015) 0.79
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Enhancement of NAD+-dependent SIRT1 deacetylase activity by methylselenocysteine resets the circadian clock in carcinogen-treated mammary epithelial cells. Oncotarget (2015) 0.77
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The NAD+-dependent deacetylase SIRT1 modulates CLOCK-mediated chromatin remodeling and circadian control. Cell (2008) 6.44
SIRT1 regulates circadian clock gene expression through PER2 deacetylation. Cell (2008) 5.68
Circadian regulator CLOCK is a histone acetyltransferase. Cell (2006) 5.24
Rhythmic CLOCK-BMAL1 binding to multiple E-box motifs drives circadian Dbp transcription and chromatin transitions. Nat Genet (2006) 5.08
The biochemistry of sirtuins. Annu Rev Biochem (2006) 4.32
Rhythmic histone acetylation underlies transcription in the mammalian circadian clock. Nature (2002) 4.13
CLOCK-mediated acetylation of BMAL1 controls circadian function. Nature (2007) 2.65
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Histone acetyltransferase-dependent chromatin remodeling and the vascular clock. J Biol Chem (2003) 1.77
The polycomb group protein EZH2 is required for mammalian circadian clock function. J Biol Chem (2006) 1.67
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White Collar-1, a circadian blue light photoreceptor, binding to the frequency promoter. Science (2002) 3.85
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Conformational switching in the fungal light sensor Vivid. Science (2007) 2.75
Rhythmic binding of a WHITE COLLAR-containing complex to the frequency promoter is inhibited by FREQUENCY. Proc Natl Acad Sci U S A (2003) 2.09
A role for casein kinase 2 in the mechanism underlying circadian temperature compensation. Cell (2009) 1.89
Execution of the circadian negative feedback loop in Neurospora requires the ATP-dependent chromatin-remodeling enzyme CLOCKSWITCH. Mol Cell (2007) 1.85
Quantitative proteomics reveals a dynamic interactome and phase-specific phosphorylation in the Neurospora circadian clock. Mol Cell (2009) 1.80
Post-translational modifications in circadian rhythms. Trends Biochem Sci (2009) 1.80
Fully codon-optimized luciferase uncovers novel temperature characteristics of the Neurospora clock. Eukaryot Cell (2007) 1.75
A role for Id2 in regulating photic entrainment of the mammalian circadian system. Curr Biol (2009) 1.70
Role for antisense RNA in regulating circadian clock function in Neurospora crassa. Nature (2003) 1.70
The circadian clock of Neurospora crassa. FEMS Microbiol Rev (2011) 1.69
The band mutation in Neurospora crassa is a dominant allele of ras-1 implicating RAS signaling in circadian output. Genes Dev (2007) 1.65
The novel ER membrane protein PRO41 is essential for sexual development in the filamentous fungus Sordaria macrospora. Mol Microbiol (2007) 1.63
The Neurospora checkpoint kinase 2: a regulatory link between the circadian and cell cycles. Science (2006) 1.62
Genome-wide analysis of light-inducible responses reveals hierarchical light signalling in Neurospora. EMBO J (2009) 1.58
Temperature-modulated alternative splicing and promoter use in the Circadian clock gene frequency. Mol Biol Cell (2005) 1.52
Genetic and molecular analysis of phytochromes from the filamentous fungus Neurospora crassa. Eukaryot Cell (2005) 1.45
The frequency gene is required for temperature-dependent regulation of many clock-controlled genes in Neurospora crassa. Genetics (2003) 1.42
The relationship between FRQ-protein stability and temperature compensation in the Neurospora circadian clock. Proc Natl Acad Sci U S A (2005) 1.42
Roles for WHITE COLLAR-1 in circadian and general photoperception in Neurospora crassa. Genetics (2003) 1.41
The PAS/LOV protein VIVID supports a rapidly dampened daytime oscillator that facilitates entrainment of the Neurospora circadian clock. Genes Dev (2005) 1.38
Physical interaction between VIVID and white collar complex regulates photoadaptation in Neurospora. Proc Natl Acad Sci U S A (2010) 1.36
Circadian rhythmicity by autocatalysis. PLoS Comput Biol (2006) 1.32
Long and short isoforms of Neurospora clock protein FRQ support temperature-compensated circadian rhythms. FEBS Lett (2007) 1.25
Cross-species microarray hybridization to identify developmentally regulated genes in the filamentous fungus Sordaria macrospora. Mol Genet Genomics (2005) 1.23
Closing the circadian negative feedback loop: FRQ-dependent clearance of WC-1 from the nucleus. Genes Dev (2008) 1.22
Light and clock expression of the Neurospora clock gene frequency is differentially driven by but dependent on WHITE COLLAR-2. Genetics (2002) 1.18
CHD1 remodels chromatin and influences transient DNA methylation at the clock gene frequency. PLoS Genet (2011) 1.16
Neurospora illuminates fungal photoreception. Fungal Genet Biol (2010) 1.15
Assignment of an essential role for the Neurospora frequency gene in circadian entrainment to temperature cycles. Proc Natl Acad Sci U S A (2005) 1.11
A high-density single nucleotide polymorphism map for Neurospora crassa. Genetics (2008) 1.10
A nitrate-induced frq-less oscillator in Neurospora crassa. J Biol Rhythms (2004) 1.10
FRQ-interacting RNA helicase mediates negative and positive feedback in the Neurospora circadian clock. Genetics (2009) 1.08
The fungal pathogen Aspergillus fumigatus regulates growth, metabolism, and stress resistance in response to light. MBio (2013) 1.07
Structure of a light-activated LOV protein dimer that regulates transcription. Sci Signal (2011) 1.06
Functional analysis of the Aspergillus nidulans kinome. PLoS One (2013) 1.05
Neurospora clock-controlled gene 9 (ccg-9) encodes trehalose synthase: circadian regulation of stress responses and development. Eukaryot Cell (2002) 1.04
High-throughput construction of gene deletion cassettes for generation of Neurospora crassa knockout strains. Methods Mol Biol (2010) 1.03
High-resolution spatiotemporal analysis of gene expression in real time: in vivo analysis of circadian rhythms in Neurospora crassa using a FREQUENCY-luciferase translational reporter. Fungal Genet Biol (2012) 1.02
Genetic and molecular characterization of a cryptochrome from the filamentous fungus Neurospora crassa. Eukaryot Cell (2010) 0.99
Fungal functional genomics: tunable knockout-knock-in expression and tagging strategies. Eukaryot Cell (2009) 0.97
Global analysis of serine-threonine protein kinase genes in Neurospora crassa. Eukaryot Cell (2011) 0.97
A phylogenetically conserved DNA damage response resets the circadian clock. J Biol Rhythms (2009) 0.96
Simulating dark expressions and interactions of frq and wc-1 in the Neurospora circadian clock. Biophys J (2007) 0.94
A developmental cycle masks output from the circadian oscillator under conditions of choline deficiency in Neurospora. Proc Natl Acad Sci U S A (2007) 0.88
Light-inducible system for tunable protein expression in Neurospora crassa. G3 (Bethesda) (2012) 0.86
Live-cell monitoring of periodic gene expression in synchronous human cells identifies Forkhead genes involved in cell cycle control. Mol Biol Cell (2012) 0.86
High-throughput production of gene replacement mutants in Neurospora crassa. Methods Mol Biol (2011) 0.85
Retinoic acid mediates long-paced oscillations in retinoid receptor activity: evidence for a potential role for RIP140. PLoS One (2009) 0.84
Modulation of clock gene expression by the transcriptional coregulator receptor interacting protein 140 (RIP140). J Biol Rhythms (2011) 0.84
Fungal photobiology: visible light as a signal for stress, space and time. Curr Genet (2014) 0.83
A kinetic study of the effects of light on circadian rhythmicity of the frq promoter of Neurospora crassa. J Biol Rhythms (2014) 0.80
The molecular workings of the Neurospora biological clock. Novartis Found Symp (2003) 0.80
CLOCK leaves its mark on histones. Trends Biochem Sci (2006) 0.79
Aging well with a little wine and a good clock. Cell (2013) 0.79
Analysis of circadian output rhythms of gene expression in Neurospora and mammalian cells in culture. Methods Enzymol (2005) 0.78
Bright to dim oscillatory response of the Neurospora circadian oscillator. J Biol Rhythms (2014) 0.78
Homology effects: the difference between 1 and 2. Adv Genet (2002) 0.78
Circadian rhythms: phosphorylating the CLOCK. Cell Cycle (2010) 0.78
Cell biology: A fable of too much too fast. Nature (2013) 0.76