Published in CMAJ on July 29, 2008
Should patient characteristics influence target anticoagulation intensity for stroke prevention in nonvalvular atrial fibrillation?: the ATRIA study. Circ Cardiovasc Qual Outcomes (2009) 1.29
Effect of an interactive voice response system on oral anticoagulant management. CMAJ (2009) 1.08
Point-of-Care International Normalized Ratio (INR) Monitoring Devices for Patients on Long-term Oral Anticoagulation Therapy: An Evidence-Based Analysis. Ont Health Technol Assess Ser (2009) 1.03
Menaquinones, bacteria, and the food supply: the relevance of dairy and fermented food products to vitamin K requirements. Adv Nutr (2013) 0.88
Drug interactions with phenprocoumon and the risk of serious haemorrhage: a nested case-control study in a large population-based German database. Eur J Clin Pharmacol (2011) 0.87
Low-intensity adjusted-dose warfarin for the prevention of hemodialysis catheter failure: a randomized, controlled trial. Clin J Am Soc Nephrol (2011) 0.83
Effect of genetic variants, especially CYP2C9 and VKORC1, on the pharmacology of warfarin. Semin Thromb Hemost (2012) 0.81
Vitamin K antagonist use: evidence of the difficulty of achieving and maintaining target INR range and subsequent consequences. Thromb J (2016) 0.81
Effects of computer-assisted oral anticoagulant therapy. Thromb J (2012) 0.80
Cost effectiveness of new oral anticoagulants for stroke prevention in patients with atrial fibrillation in two different European healthcare settings. Am J Cardiovasc Drugs (2014) 0.79
Thromboembolism. BMJ Clin Evid (2011) 0.79
A team-based approach to warfarin management in long term care: a feasibility study of the MEDeINR electronic decision support system. BMC Geriatr (2010) 0.79
Differences in patient outcomes and chronic care management of oral anticoagulant therapy: an explorative study. BMC Health Serv Res (2011) 0.78
A higher international normalized ratio may be better for your patient. CMAJ (2008) 0.78
Increased frequency of CYP2C9 variant alleles and homozygous VKORC1*2B carriers in warfarin-treated patients with excessive INR response. Eur J Clin Pharmacol (2010) 0.77
Effect of CYP2C9, VKORC1, and CYP4F2 polymorphisms on warfarin maintenance dose in children aged less than 18 years: a protocol for systematic review and meta-analysis. Syst Rev (2016) 0.77
Concurrent use of tramadol and oral vitamin K antagonists and the risk of excessive anticoagulation: a register-based nested case-control study. Eur J Clin Pharmacol (2012) 0.77
Minor Oral Surgery Procedures in Patients Taking Warfarin: A 5-year retrospective study at Sultan Qaboos University Hospital, Sultanate of Oman. Sultan Qaboos Univ Med J (2009) 0.77
Association Between Usual Vitamin K Intake and Anticoagulation in Patients Under Warfarin Therapy. Clin Nutr Res (2015) 0.75
Review: anticoagulation with INRs less than 2 or between 3 and 5 increases risk for thromboembolic or hemorrhagic events. ACP J Club (2008) 0.75
A Proposal for an Individualized Pharmacogenetic-Guided Warfarin Dosage Regimen for Puerto Rican Patients Commencing Anticoagulation Therapy. J Pharmacogenomics Pharmacoproteomics (2014) 0.75
Implications of using different methods to characterise anticoagulant control in patients with second generation mechanical heart valve prostheses. PLoS One (2014) 0.75
Cost-effectiveness of pharmacogenetic-guided dosing of warfarin in the United Kingdom and Sweden. Pharmacogenomics J (2016) 0.75
Massachusetts Health Reform Cost Less and Was More Effective for Uninsured Individuals With Venous Thromboembolism: A Cost-Effectiveness Analysis. Med Care (2016) 0.75
Comparison of low-intensity warfarin therapy with conventional-intensity warfarin therapy for long-term prevention of recurrent venous thromboembolism. N Engl J Med (2003) 8.55
Comparison of warfarin and aspirin for symptomatic intracranial arterial stenosis. N Engl J Med (2005) 7.92
A comparison of warfarin and aspirin for the prevention of recurrent ischemic stroke. N Engl J Med (2001) 7.07
Effect of intensity of oral anticoagulation on stroke severity and mortality in atrial fibrillation. N Engl J Med (2003) 6.70
Regression analyses of counts and rates: Poisson, overdispersed Poisson, and negative binomial models. Psychol Bull (1995) 6.52
Optimal oral anticoagulant therapy in patients with mechanical heart valves. N Engl J Med (1995) 5.16
Thromboembolic and bleeding complications in patients with mechanical heart valve prostheses. Circulation (1994) 3.65
Different intensities of oral anticoagulant therapy in the treatment of proximal-vein thrombosis. N Engl J Med (1982) 3.16
Effect of study setting on anticoagulation control: a systematic review and metaregression. Chest (2006) 2.79
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Optimal oral anticoagulant therapy in patients with nonrheumatic atrial fibrillation and recent cerebral ischemia. The European Atrial Fibrillation Trial Study Group. N Engl J Med (1995) 2.51
Hemorrhagic complications of anticoagulant treatment: the Seventh ACCP Conference on Antithrombotic and Thrombolytic Therapy. Chest (2004) 2.50
Oral anticoagulation management in primary care with the use of computerized decision support and near-patient testing: a randomized, controlled trial. Arch Intern Med (2000) 2.36
Incidence of recurrent thromboembolic and bleeding complications among patients with venous thromboembolism in relation to both malignancy and achieved international normalized ratio: a retrospective analysis. J Clin Oncol (2000) 2.35
"Our complication rates are lower than theirs": statistical critique of heart valve comparisons. J Thorac Cardiovasc Surg (2003) 2.25
Burden of potentially avoidable anticoagulant-associated hemorrhagic and thromboembolic events in the elderly. Chest (2007) 2.23
Death and disability from warfarin-associated intracranial and extracranial hemorrhages. Am J Med (2007) 2.16
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Evaluation of computerized decision support for oral anticoagulation management based in primary care. Br J Gen Pract (1996) 1.83
Warfarin anticoagulation and outcomes in patients with atrial fibrillation: a systematic review and metaanalysis. Chest (2004) 1.80
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Invited commentary: benefits of heterogeneity in meta-analysis of data from epidemiologic studies. Am J Epidemiol (1995) 1.58
Oral anticoagulation and risk of death: a medical record linkage study. BMJ (2002) 1.56
A randomized trial of anticoagulants versus aspirin after cerebral ischemia of presumed arterial origin. The Stroke Prevention in Reversible Ischemia Trial (SPIRIT) Study Group. Ann Neurol (1997) 1.48
An assessment of methods to combine published survival curves. Med Decis Making (2000) 1.47
Multicentre randomised study of computerised anticoagulant dosage. European Concerted Action on Anticoagulation. Lancet (1998) 1.47
Descriptive analysis of the process and quality of oral anticoagulation management in real-life practice in patients with chronic non-valvular atrial fibrillation: the international study of anticoagulation management (ISAM). J Thromb Thrombolysis (2007) 1.47
Minimum effective intensity of oral anticoagulant therapy in primary prevention of coronary heart disease. Arch Intern Med (2000) 1.44
Assessment of therapeutic quality control in a long-term anticoagulant trial in post-myocardial infarction patients. Thromb Haemost (1994) 1.41
Is INR between 2.0 and 3.0 the optimal level for Chinese patients on warfarin therapy for moderate-intensity anticoagulation? Br J Clin Pharmacol (2005) 1.29
Thrombotic events during oral anticoagulant treatment: results of the inception-cohort, prospective, collaborative ISCOAT study: ISCOAT study group (Italian Study on Complications of Oral Anticoagulant Therapy). Thromb Haemost (1997) 1.27
Self management of oral anticoagulant therapy after heart valve replacement. Eur J Cardiothorac Surg (1997) 1.26
Optimal INR for prevention of stroke and death in atrial fibrillation: a critical appraisal. Thromb Res (2004) 1.22
Comparison of anticoagulation clinic patient outcomes with outcomes from traditional care in a family medicine clinic. J Am Board Fam Pract (2001) 1.18
Lower intensity anticoagulation therapy results in lower complication rates with the St. Jude Medical prosthesis. J Thorac Cardiovasc Surg (1994) 1.14
Factors influencing physicians' reported use of anticoagulation therapy in nonvalvular atrial fibrillation: a cross-sectional survey. Clin Ther (2003) 1.10
Medium intensity oral anticoagulants versus aspirin after cerebral ischaemia of arterial origin (ESPRIT): a randomised controlled trial. Lancet Neurol (2007) 1.08
Meta-analytic methods for pooling rates when follow-up duration varies: a case study. BMC Med Res Methodol (2004) 1.06
Effect of computer-aided management on the quality of treatment in anticoagulated patients: a prospective, randomized, multicenter trial of APROAT (Automated PRogram for Oral Anticoagulant Treatment). Haematologica (2001) 1.06
Comparison of oral anticoagulant control by a nurse-practitioner using a computer decision-support system with that by clinicians. Clin Lab Haematol (1997) 1.00
Comparison of three methods to assess therapeutic quality control of treatment with vitamin K antagonists. Thromb Haemost (1999) 0.97
Efficient operation of a high-volume anticoagulation clinic. Am J Health Syst Pharm (1999) 0.95
Antiplatelet and anticoagulation for patients with prosthetic heart valves. Cochrane Database Syst Rev (2003) 0.91
Optimal intensity of oral anticoagulant therapy after myocardial infarction. J Am Coll Cardiol (1996) 0.89
Should aspirin be continued in patients started on warfarin? J Gen Intern Med (2004) 0.86
Bleeding risk factors in chronic oral anticoagulation with acenocoumarol. Am J Hematol (2000) 0.84
Oral anticoagulant therapy during and after coronary angioplasty the intensity and duration of anticoagulation are essential to reduce thrombotic complications. Circulation (2001) 0.84
Oral anticoagulation for cerebral ischemia of arterial origin: high initial bleeding risk. Neurology (2001) 0.84
Optimal oral anticoagulant intensity to prevent secondary ischemic and hemorrhagic events in patients after infrainguinal bypass graft surgery. Dutch BOA Study Group. J Vasc Surg (2001) 0.84
The lowest effective intensity of prophylactic anticoagulation for patients with atrial fibrillation. Cerebrovasc Dis (2005) 0.83
Comparison of outcomes using 2 delivery models of anticoagulation care. Arch Intern Med (2006) 0.82
Low rate of bleeding and thrombotic complications of oral anticoagulant therapy independent of age in the real-practice of an anticoagulation clinic. Blood Coagul Fibrinolysis (2003) 0.80
Instability of anticoagulation intensity contributes to occurrence of ischemic stroke in patients with non-rheumatic atrial fibrillation. Jpn Circ J (2001) 0.79
Effects of aerobic training, resistance training, or both on glycemic control in type 2 diabetes: a randomized trial. Ann Intern Med (2007) 7.99
Adverse events among medical patients after discharge from hospital. CMAJ (2004) 7.89
Daily sedation interruption in mechanically ventilated critically ill patients cared for with a sedation protocol: a randomized controlled trial. JAMA (2012) 6.69
Hypothermia therapy after traumatic brain injury in children. N Engl J Med (2008) 6.10
How quickly do systematic reviews go out of date? A survival analysis. Ann Intern Med (2007) 5.86
Tiotropium in combination with placebo, salmeterol, or fluticasone-salmeterol for treatment of chronic obstructive pulmonary disease: a randomized trial. Ann Intern Med (2007) 5.51
A modification of the Elixhauser comorbidity measures into a point system for hospital death using administrative data. Med Care (2009) 5.13
Association between suicide attempts and selective serotonin reuptake inhibitors: systematic review of randomised controlled trials. BMJ (2005) 4.74
Selecting patients with atrial fibrillation for anticoagulation: stroke risk stratification in patients taking aspirin. Circulation (2004) 4.45
Does this patient have deep vein thrombosis? JAMA (2006) 4.44
Early combination antibiotic therapy yields improved survival compared with monotherapy in septic shock: a propensity-matched analysis. Crit Care Med (2010) 4.39
Proportion of hospital readmissions deemed avoidable: a systematic review. CMAJ (2011) 4.37
The effects of on-screen, point of care computer reminders on processes and outcomes of care. Cochrane Database Syst Rev (2009) 4.22
Reliability of point-of-care testing for glucose measurement in critically ill adults. Crit Care Med (2005) 3.84
Prophylactic vaccination against human papillomavirus infection and disease in women: a systematic review of randomized controlled trials. CMAJ (2007) 3.77
When laboratories report estimated glomerular filtration rates in addition to serum creatinines, nephrology consults increase. Kidney Int (2009) 3.70
CONSORT 2010 changes and testing blindness in RCTs. Lancet (2010) 3.68
Derivation and validation of an index to predict early death or unplanned readmission after discharge from hospital to the community. CMAJ (2010) 3.60
Clinical consequences of red cell storage in the critically ill. Transfusion (2006) 3.57
Systematic review: the Trousseau syndrome revisited: should we screen extensively for cancer in patients with venous thromboembolism? Ann Intern Med (2008) 3.56
Overdiagnosis of asthma in obese and nonobese adults. CMAJ (2008) 3.23
Clinical inertia in response to inadequate glycemic control: do specialists differ from primary care physicians? Diabetes Care (2005) 3.02
Correlates of severe disease in patients with 2009 pandemic influenza (H1N1) virus infection. CMAJ (2010) 2.96
Fluids after cardiac surgery: a pilot study of the use of colloids versus crystalloids. Crit Care Med (2010) 2.82
Effect of study setting on anticoagulation control: a systematic review and metaregression. Chest (2006) 2.79
Prevalence of information gaps in the emergency department and the effect on patient outcomes. CMAJ (2003) 2.76
Safety of cell therapy with mesenchymal stromal cells (SafeCell): a systematic review and meta-analysis of clinical trials. PLoS One (2012) 2.75
Clinical outcomes following institution of the Canadian universal leukoreduction program for red blood cell transfusions. JAMA (2003) 2.74
Time-dependent bias was common in survival analyses published in leading clinical journals. J Clin Epidemiol (2004) 2.70
Effect of point-of-care computer reminders on physician behaviour: a systematic review. CMAJ (2010) 2.67
The association between continuity of care and outcomes: a systematic and critical review. J Eval Clin Pract (2010) 2.52
Impact of specialist follow-up in outpatients with congestive heart failure. CMAJ (2005) 2.50
Overuse of magnetic resonance imaging. JAMA Intern Med (2013) 2.46
Ottawa Hospital Patient Safety Study: incidence and timing of adverse events in patients admitted to a Canadian teaching hospital. CMAJ (2004) 2.45
Preservation of renal function following partial or radical nephrectomy using 24-hour creatinine clearance. Eur Urol (2008) 2.43
Activated protein C and septic shock: a propensity-matched cohort study*. Crit Care Med (2012) 2.39
Effect of weight reduction on respiratory function and airway reactivity in obese women. Chest (2004) 2.35
Early intravenous unfractionated heparin and mortality in septic shock. Crit Care Med (2008) 2.35
Burden of potentially avoidable anticoagulant-associated hemorrhagic and thromboembolic events in the elderly. Chest (2007) 2.23
Association of diagnostic radiation exposure and second abdominal-pelvic malignancies after testicular cancer. J Clin Oncol (2011) 2.18
Electronically screening discharge summaries for adverse medical events. J Am Med Inform Assoc (2003) 2.15
Identifying Obstructive Sleep Apnea in Administrative Data: A Study of Diagnostic Accuracy. Anesthesiology (2015) 2.12
The effect of pentoxifylline on proteinuria in diabetic kidney disease: a meta-analysis. Am J Kidney Dis (2008) 2.09
Hospital mortality: when failure is not a good measure of success. CMAJ (2008) 1.98
A prospective cohort study found that provider and information continuity was low after patient discharge from hospital. J Clin Epidemiol (2010) 1.95
Administrative database research infrequently used validated diagnostic or procedural codes. J Clin Epidemiol (2011) 1.94
The effect of hospital occupancy on emergency department length of stay and patient disposition. Acad Emerg Med (2003) 1.93
Impact of ambulatory surgery day of the week on postoperative outcomes: a population-based cohort study. Can J Anaesth (2015) 1.93
Threats to validity in the design and conduct of preclinical efficacy studies: a systematic review of guidelines for in vivo animal experiments. PLoS Med (2013) 1.92
Mapping out the emergency department disposition decision for high-acuity patients. Ann Emerg Med (2012) 1.90
A novel equation to estimate glomerular filtration rate using beta-trace protein. Clin Chem (2007) 1.85
Assessment of thiopurine S-methyltransferase activity in patients prescribed thiopurines: a systematic review. Ann Intern Med (2011) 1.81
Revisiting transfusion practices in critically ill patients. Crit Care Med (2005) 1.78
The Age of Blood Evaluation (ABLE) randomized controlled trial: study design. Transfus Med Rev (2011) 1.71
Incidence of potentially avoidable urgent readmissions and their relation to all-cause urgent readmissions. CMAJ (2011) 1.69
Information exchange among physicians caring for the same patient in the community. CMAJ (2008) 1.67
Effect of beta-blocker prescription on the incidence of postoperative myocardial infarction after hip and knee arthroplasty. Anesthesiology (2009) 1.65
Use of primary prevention implantable cardioverter-defibrillators in a population-based cohort is associated with a significant survival benefit. Circ Arrhythm Electrophysiol (2012) 1.60
A systematic review and meta-analysis of efficacy, cost-effectiveness, and safety of selected complementary and alternative medicine for neck and low-back pain. Evid Based Complement Alternat Med (2011) 1.59
A risk scoring system to identify emergency department patients with heart failure at high risk for serious adverse events. Acad Emerg Med (2013) 1.59
A pilot trial evaluating the clinical effects of prolonged storage of red cells. Anesth Analg (2005) 1.59
Prevalence, risk factors, and outcomes of delirium in mechanically ventilated adults. Crit Care Med (2015) 1.58
Systematic review of measures of clinical significance employed in randomized controlled trials of drugs for dementia. J Am Geriatr Soc (2009) 1.54
The prognostic significance of capsular incision into tumor during radical prostatectomy. Eur Urol (2010) 1.53
Calcineurin inhibitor withdrawal from sirolimus-based therapy in kidney transplantation: a systematic review of randomized trials. Am J Transplant (2005) 1.53
Continuous multi-parameter heart rate variability analysis heralds onset of sepsis in adults. PLoS One (2009) 1.52
Resuscitating patients with early severe sepsis: a Canadian multicentre observational study. Can J Anaesth (2007) 1.52
Maternal age and risk of stillbirth: a systematic review. CMAJ (2008) 1.51
Long-term outcomes and resource utilization of endovascular versus open repair of abdominal aortic aneurysms in Ontario. J Vasc Surg (2010) 1.47
Red blood cell transfusion practices amongst Canadian anesthesiologists: a survey. Can J Anaesth (2006) 1.47
Exacerbation frequency and clinical outcomes in adult patients with cystic fibrosis. Thorax (2011) 1.46
Using the Johns Hopkins Aggregated Diagnosis Groups (ADGs) to predict mortality in a general adult population cohort in Ontario, Canada. Med Care (2011) 1.43
Unplanned readmissions after hospital discharge among patients identified as being at high risk for readmission using a validated predictive algorithm. Open Med (2011) 1.43
Cardiac complications in patients with community-acquired pneumonia: a systematic review and meta-analysis of observational studies. PLoS Med (2011) 1.42
Reducing the amount of blood transfused: a systematic review of behavioral interventions to change physicians' transfusion practices. Arch Intern Med (2005) 1.41
Clinical review: Canadian National Advisory Committee on Blood and Blood Products--Massive transfusion consensus conference 2011: report of the panel. Crit Care (2011) 1.40
Estimating glomerular filtration rate in kidney transplantation: is the new chronic kidney disease epidemiology collaboration equation any better? Clin Chem (2009) 1.39
A survey of Canadian intensivists' resuscitation practices in early septic shock. Crit Care (2007) 1.37
The effect of hospital-acquired Clostridium difficile infection on in-hospital mortality. Arch Intern Med (2010) 1.36