Published in Development on August 06, 2008
Hairy tale of signaling in hair follicle development and cycling. Semin Cell Dev Biol (2012) 1.22
Micro-RNA-31 controls hair cycle-associated changes in gene expression programs of the skin and hair follicle. FASEB J (2010) 1.21
Epidermal ablation of Dlx3 is linked to IL-17-associated skin inflammation. Proc Natl Acad Sci U S A (2011) 1.05
Palmitoylation regulates epidermal homeostasis and hair follicle differentiation. PLoS Genet (2009) 1.04
Signaling involved in hair follicle morphogenesis and development. Int J Mol Sci (2014) 0.97
Abnormal hair follicle development and altered cell fate of follicular keratinocytes in transgenic mice expressing DeltaNp63alpha. Development (2010) 0.96
Abnormal placental development and early embryonic lethality in EpCAM-null mice. PLoS One (2009) 0.95
Neural crest deletion of Dlx3 leads to major dentin defects through down-regulation of Dspp. J Biol Chem (2012) 0.93
Multifactorial ERβ and NOTCH1 control of squamous differentiation and cancer. J Clin Invest (2014) 0.92
Hair keratin mutations in tooth enamel increase dental decay risk. J Clin Invest (2014) 0.91
To grow or not to grow: hair morphogenesis and human genetic hair disorders. Semin Cell Dev Biol (2013) 0.86
Mutations in the endothelin receptor type A cause mandibulofacial dysostosis with alopecia. Am J Hum Genet (2015) 0.86
Mutant DLX 3 disrupts odontoblast polarization and dentin formation. Dev Biol (2010) 0.85
Cessation of epithelial Bmp signaling switches the differentiation of crown epithelia to the root lineage in a β-catenin-dependent manner. Mol Cell Biol (2013) 0.85
Post-transcriptional Regulation of Keratinocyte Progenitor Cell Expansion, Differentiation and Hair Follicle Regression by miR-22. PLoS Genet (2015) 0.83
Hairless plays a role in formation of inner root sheath via regulation of Dlx3 gene. J Biol Chem (2012) 0.82
Amelogenesis Imperfecta; Genes, Proteins, and Pathways. Front Physiol (2017) 0.82
Cutaneous retinoic acid levels determine hair follicle development and downgrowth. J Biol Chem (2012) 0.80
Transcriptional profiling of ectoderm specification to keratinocyte fate in human embryonic stem cells. PLoS One (2015) 0.80
SUMOylation of DLX3 by SUMO1 promotes its transcriptional activity. J Cell Biochem (2011) 0.79
ILK modulates epithelial polarity and matrix formation in hair follicles. Mol Biol Cell (2013) 0.79
Multiple roles of integrin-linked kinase in epidermal development, maturation and pigmentation revealed by molecular profiling. PLoS One (2012) 0.79
In vivo impact of Dlx3 conditional inactivation in neural crest-derived craniofacial bones. J Cell Physiol (2013) 0.78
The homeoprotein DLX3 and tumor suppressor p53 co-regulate cell cycle progression and squamous tumor growth. Oncogene (2015) 0.78
Functional Characterization of a Single Nucleotide Polymorphism in the 3' Untranslated Region of Sheep DLX3 Gene. PLoS One (2015) 0.76
Distal-less 3 haploinsufficiency results in elevated placental oxidative stress and altered fetal growth kinetics in the mouse. Placenta (2012) 0.76
Drug discovery for alopecia: gone today, hair tomorrow. Expert Opin Drug Discov (2015) 0.75
Senescence: novel insight into DLX3 mutations leading to enhanced bone formation in Tricho-Dento-Osseous syndrome. Sci Rep (2016) 0.75
DLX3 interacts with GCM1 and inhibits its transactivation-stimulating activity in a homeodomain-dependent manner in human trophoblast-derived cells. Sci Rep (2017) 0.75
Gata6 promotes hair follicle progenitor cell renewal by genome maintenance during proliferation. EMBO J (2016) 0.75
Theria-specific homeodomain and cis-regulatory element evolution of the Dlx3-4 bigene cluster in 12 different mammalian species. J Exp Zool B Mol Dev Evol (2012) 0.75
Adult hair follicle stem cells do not retain the older DNA strands in vivo during normal tissue homeostasis. Chromosome Res (2013) 0.75
Epidermal stem cells in the isthmus/infundibulum influence hair shaft differentiation: evidence from targeted DLX3 deletion. J Invest Dermatol (2014) 0.75
A novel DLX3-PKC integrated signaling network drives keratinocyte differentiation. Cell Death Differ (2017) 0.75
CtBP1 overexpression in keratinocytes perturbs skin homeostasis. J Invest Dermatol (2013) 0.75
Emerging roles of transit-amplifying cells in tissue regeneration and cancer. Wiley Interdiscip Rev Dev Biol (2017) 0.75
Role of thymosin beta 4 in hair growth. Mol Genet Genomics (2016) 0.75
VEGF165 induces differentiation of hair follicle stem cells into endothelial cells and plays a role in in vivo angiogenesis. J Cell Mol Med (2017) 0.75
Generalized lacZ expression with the ROSA26 Cre reporter strain. Nat Genet (1999) 55.63
Label-retaining cells reside in the bulge area of pilosebaceous unit: implications for follicular stem cells, hair cycle, and skin carcinogenesis. Cell (1990) 12.13
beta-Catenin controls hair follicle morphogenesis and stem cell differentiation in the skin. Cell (2001) 8.41
De Novo hair follicle morphogenesis and hair tumors in mice expressing a truncated beta-catenin in skin. Cell (1998) 7.95
Involvement of follicular stem cells in forming not only the follicle but also the epidermis. Cell (2000) 6.93
WNT signals are required for the initiation of hair follicle development. Dev Cell (2002) 6.63
Morphogenesis and renewal of hair follicles from adult multipotent stem cells. Cell (2001) 6.37
The secret life of the hair follicle. Trends Genet (1992) 4.94
Cyclic dermal BMP signalling regulates stem cell activation during hair regeneration. Nature (2008) 4.67
Tcf3 and Lef1 regulate lineage differentiation of multipotent stem cells in skin. Genes Dev (2001) 4.62
Scratching the surface of skin development. Nature (2007) 4.61
The sequence specificity of homeodomain-DNA interaction. Cell (1988) 4.22
Molecular mechanisms regulating hair follicle development. J Invest Dermatol (2002) 4.16
Distinct stem cell populations regenerate the follicle and interfollicular epidermis. Dev Cell (2005) 3.98
Keratin 15 promoter targets putative epithelial stem cells in the hair follicle bulge. J Invest Dermatol (2003) 3.72
New aspects of Wnt signaling pathways in higher vertebrates. Curr Opin Genet Dev (2001) 3.63
Essential role for Sonic hedgehog during hair follicle morphogenesis. Dev Biol (1999) 3.62
Epithelial Bmpr1a regulates differentiation and proliferation in postnatal hair follicles and is essential for tooth development. Development (2004) 3.46
Loss of a quiescent niche but not follicle stem cells in the absence of bone morphogenetic protein signaling. Proc Natl Acad Sci U S A (2007) 3.16
Molecular principles of hair follicle induction and morphogenesis. Bioessays (2005) 3.08
Noggin is a mesenchymally derived stimulator of hair-follicle induction. Nat Cell Biol (1999) 2.99
GATA-3: an unexpected regulator of cell lineage determination in skin. Genes Dev (2003) 2.97
The cutting-edge of mammalian development; how the embryo makes teeth. Nat Rev Genet (2004) 2.89
Lhx2 maintains stem cell character in hair follicles. Science (2006) 2.78
Defining BMP functions in the hair follicle by conditional ablation of BMP receptor IA. J Cell Biol (2003) 2.65
Transient activation of beta -catenin signaling in cutaneous keratinocytes is sufficient to trigger the active growth phase of the hair cycle in mice. Genes Dev (2003) 2.59
A survey of transformation markers in differentiating epidermal cell lines in culture. Cancer Res (1980) 2.53
BMP signaling in dermal papilla cells is required for their hair follicle-inductive properties. Genes Dev (2008) 2.41
Smad7-induced beta-catenin degradation alters epidermal appendage development. Dev Cell (2006) 2.41
WNT signaling in the control of hair growth and structure. Dev Biol (1999) 2.13
Inhibition of Bmp signaling affects growth and differentiation in the anagen hair follicle. EMBO J (2000) 2.01
Regulation of organogenesis. Common molecular mechanisms regulating the development of teeth and other organs. Int J Dev Biol (1995) 2.01
Dlx3 transcriptional regulation of osteoblast differentiation: temporal recruitment of Msx2, Dlx3, and Dlx5 homeodomain proteins to chromatin of the osteocalcin gene. Mol Cell Biol (2004) 1.99
Placental failure in mice lacking the homeobox gene Dlx3. Proc Natl Acad Sci U S A (1999) 1.96
Altered HOX gene expression in human skin and breast cancer cells. Cancer Biol Ther (2003) 1.86
Hoxc13 mutant mice lack external hair. Genes Dev (1998) 1.84
Generation of the primary hair follicle pattern. Proc Natl Acad Sci U S A (2006) 1.72
'Cyclic alopecia' in Msx2 mutants: defects in hair cycling and hair shaft differentiation. Development (2003) 1.70
Identification of a mutation in DLX3 associated with tricho-dento-osseous (TDO) syndrome. Hum Mol Genet (1998) 1.68
NF-kappaB transmits Eda A1/EdaR signalling to activate Shh and cyclin D1 expression, and controls post-initiation hair placode down growth. Development (2006) 1.66
Ectodysplasin has a dual role in ectodermal organogenesis: inhibition of Bmp activity and induction of Shh expression. Development (2007) 1.53
The transcriptional repressor CDP (Cutl1) is essential for epithelial cell differentiation of the lung and the hair follicle. Genes Dev (2001) 1.50
Regulation of epidermal differentiation by a Distal-less homeodomain gene. J Cell Biol (1996) 1.49
The mammary bud as a skin appendage: unique and shared aspects of development. J Mammary Gland Biol Neoplasia (2006) 1.39
Keratins of the human hair follicle. Int Rev Cytol (2005) 1.34
Evidence that the satin hair mutant gene Foxq1 is among multiple and functionally diverse regulatory targets for Hoxc13 during hair follicle differentiation. J Biol Chem (2006) 1.34
Transcriptome and phenotypic analysis reveals Gata3-dependent signalling pathways in murine hair follicles. Development (2006) 1.32
Transcriptional activation by the homeodomain protein distal-less 3. Nucleic Acids Res (1999) 1.28
Sustained epithelial beta-catenin activity induces precocious hair development but disrupts hair follicle down-growth and hair shaft formation. Development (2008) 1.27
Genomic structure and functional control of the Dlx3-7 bigene cluster. Proc Natl Acad Sci U S A (2002) 1.22
Overexpression of Hoxc13 in differentiating keratinocytes results in downregulation of a novel hair keratin gene cluster and alopecia. Development (2001) 1.17
The role of gene duplication in the evolution and function of the vertebrate Dlx/distal-less bigene clusters. J Struct Funct Genomics (2003) 1.12
HOXC13 is involved in the regulation of human hair keratin gene expression. J Biol Chem (2001) 1.07
Dermal-epidermal interactions. Clin Dermatol (1989) 1.05
Bone morphogenetic protein-2 (BMP-2) transactivates Dlx3 through Smad1 and Smad4: alternative mode for Dlx3 induction in mouse keratinocytes. Nucleic Acids Res (2002) 1.05
The Dlx3 protein harbors basic residues required for nuclear localization, transcriptional activity and binding to Msx1. J Cell Sci (2000) 1.03
Homeobox gene Dlx3 is regulated by p63 during ectoderm development: relevance in the pathogenesis of ectodermal dysplasias. Development (2007) 1.02
Regulation and function of Dlx3 in vertebrate development. Dev Dyn (2000) 0.98
Whn and mHa3 are components of the genetic hierarchy controlling hair follicle differentiation. Mech Dev (1999) 0.94
Distinct roles for Distal-less genes Dlx3 and Dlx5 in regulating ectodermal development in Xenopus. Mol Reprod Dev (2001) 0.94
Role of Scarf and its binding target proteins in epidermal calcium homeostasis. J Biol Chem (2007) 0.92
DLX3 c.561_562delCT mutation causes attenuated phenotype of tricho-dento-osseous syndrome. Am J Med Genet A (2008) 0.92
Foxn1 is required for tissue assembly and desmosomal cadherin expression in the hair shaft. Dev Dyn (2005) 0.86
Dlx genes, p63, and ectodermal dysplasias. Birth Defects Res C Embryo Today (2005) 0.84
WNT signals are required for the initiation of hair follicle development. Dev Cell (2002) 6.63
Wnt-dependent de novo hair follicle regeneration in adult mouse skin after wounding. Nature (2007) 5.19
The miRNA-processing enzyme dicer is essential for the morphogenesis and maintenance of hair follicles. Curr Biol (2006) 3.64
Epithelial Bmpr1a regulates differentiation and proliferation in postnatal hair follicles and is essential for tooth development. Development (2004) 3.46
Wnt/beta-catenin signaling acts upstream of N-myc, BMP4, and FGF signaling to regulate proximal-distal patterning in the lung. Dev Biol (2005) 2.73
Pathological responses to oncogenic Hedgehog signaling in skin are dependent on canonical Wnt/beta3-catenin signaling. Nat Genet (2008) 2.45
Wnt-beta-catenin signaling initiates taste papilla development. Nat Genet (2006) 2.43
Pax3 functions at a nodal point in melanocyte stem cell differentiation. Nature (2005) 2.37
Wnt/beta-catenin signaling directs multiple stages of tooth morphogenesis. Dev Biol (2007) 2.26
Canonical WNT signaling promotes mammary placode development and is essential for initiation of mammary gland morphogenesis. Development (2004) 2.24
p21WAF1/Cip1 is a negative transcriptional regulator of Wnt4 expression downstream of Notch1 activation. Genes Dev (2005) 2.17
Reciprocal requirements for EDA/EDAR/NF-kappaB and Wnt/beta-catenin signaling pathways in hair follicle induction. Dev Cell (2009) 2.17
BMP2 commitment to the osteogenic lineage involves activation of Runx2 by DLX3 and a homeodomain transcriptional network. J Biol Chem (2006) 2.15
Impaired notch signaling promotes de novo squamous cell carcinoma formation. Cancer Res (2006) 2.02
Dlx3 transcriptional regulation of osteoblast differentiation: temporal recruitment of Msx2, Dlx3, and Dlx5 homeodomain proteins to chromatin of the osteocalcin gene. Mol Cell Biol (2004) 1.99
Self-organizing and stochastic behaviors during the regeneration of hair stem cells. Science (2011) 1.96
Activation of beta-catenin signaling programs embryonic epidermis to hair follicle fate. Development (2008) 1.96
Hdac1 and Hdac2 act redundantly to control p63 and p53 functions in epidermal progenitor cells. Dev Cell (2010) 1.75
Homeodomain protein Dlx3 induces phosphorylation-dependent p63 degradation. Cell Cycle (2009) 1.62
The WNT7b promoter is regulated by TTF-1, GATA6, and Foxa2 in lung epithelium. J Biol Chem (2002) 1.59
Regulation of Dlx5 and Dlx6 gene expression by p63 is involved in EEC and SHFM congenital limb defects. Development (2008) 1.55
Wnt/β-catenin pathway in podocytes integrates cell adhesion, differentiation, and survival. J Biol Chem (2011) 1.51
Canonical wnt signaling is required for pancreatic carcinogenesis. Cancer Res (2013) 1.49
Distinct functions for Wnt/β-catenin in hair follicle stem cell proliferation and survival and interfollicular epidermal homeostasis. Cell Stem Cell (2013) 1.41
Dkk2 plays an essential role in the corneal fate of the ocular surface epithelium. Development (2006) 1.41
The mammary bud as a skin appendage: unique and shared aspects of development. J Mammary Gland Biol Neoplasia (2006) 1.39
Fgf9 from dermal γδ T cells induces hair follicle neogenesis after wounding. Nat Med (2013) 1.33
Lipid defect underlies selective skin barrier impairment of an epidermal-specific deletion of Gata-3. J Cell Biol (2006) 1.28
Role of homeobox genes in the patterning, specification, and differentiation of ectodermal appendages in mammals. J Cell Physiol (2008) 1.21
Brain and muscle Arnt-like protein-1 (BMAL1) controls circadian cell proliferation and susceptibility to UVB-induced DNA damage in the epidermis. Proc Natl Acad Sci U S A (2012) 1.19
Wnt/β-catenin signaling regulates postnatal development and regeneration of the salivary gland. Stem Cells Dev (2010) 1.17
Inducible deletion of epidermal Dicer and Drosha reveals multiple functions for miRNAs in postnatal skin. Development (2012) 1.11
Epidermal ablation of Dlx3 is linked to IL-17-associated skin inflammation. Proc Natl Acad Sci U S A (2011) 1.05
Bone morphogenetic protein-2 (BMP-2) transactivates Dlx3 through Smad1 and Smad4: alternative mode for Dlx3 induction in mouse keratinocytes. Nucleic Acids Res (2002) 1.05
Expression of Frizzled genes in developing and postnatal hair follicles. J Invest Dermatol (2004) 1.04
Hopx expression defines a subset of multipotent hair follicle stem cells and a progenitor population primed to give rise to K6+ niche cells. Development (2013) 1.02
Homeobox gene Dlx3 is regulated by p63 during ectoderm development: relevance in the pathogenesis of ectodermal dysplasias. Development (2007) 1.02
DKK1 mediated inhibition of Wnt signaling in postnatal mice leads to loss of TEC progenitors and thymic degeneration. PLoS One (2010) 0.99
Molecular consequences of a frameshifted DLX3 mutant leading to Tricho-Dento-Osseous syndrome. J Biol Chem (2008) 0.99
The novel murine Ca2+-binding protein, Scarf, is differentially expressed during epidermal differentiation. J Biol Chem (2003) 0.98
Suprabasin, a novel epidermal differentiation marker and potential cornified envelope precursor. J Biol Chem (2002) 0.98
A mutation in NFkB interacting protein 1 results in cardiomyopathy and abnormal skin development in wa3 mice. Hum Mol Genet (2005) 0.96
Epidermal patterning and induction of different hair types during mouse embryonic development. Birth Defects Res C Embryo Today (2009) 0.95
Abnormal placental development and early embryonic lethality in EpCAM-null mice. PLoS One (2009) 0.95
Neural crest deletion of Dlx3 leads to major dentin defects through down-regulation of Dspp. J Biol Chem (2012) 0.93
Role of Scarf and its binding target proteins in epidermal calcium homeostasis. J Biol Chem (2007) 0.92
Hair keratin mutations in tooth enamel increase dental decay risk. J Clin Invest (2014) 0.91
Hairy math: insights into hair-follicle spacing and orientation. Cell (2007) 0.91
Increased retinoic acid levels through ablation of Cyp26b1 determine the processes of embryonic skin barrier formation and peridermal development. J Cell Sci (2012) 0.87
Cell biology: The not-so-odd couple. Nature (2009) 0.87
Cutaneous retinoic acid levels determine hair follicle development and downgrowth. J Biol Chem (2012) 0.80
SUMOylation of DLX3 by SUMO1 promotes its transcriptional activity. J Cell Biochem (2011) 0.79
Wnt signaling influences the development of murine epidermal Langerhans cells. J Invest Dermatol (2011) 0.78
In vivo impact of Dlx3 conditional inactivation in neural crest-derived craniofacial bones. J Cell Physiol (2013) 0.78
Calmodulin 4 is dispensable for epidermal barrier formation and wound healing in mice. Exp Dermatol (2014) 0.76