Genetic polymorphism of inosine triphosphate pyrophosphatase is a determinant of mercaptopurine metabolism and toxicity during treatment for acute lymphoblastic leukemia.

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Published in Clin Pharmacol Ther on August 06, 2008

Authors

G Stocco1, M H Cheok, K R Crews, T Dervieux, D French, D Pei, W Yang, C Cheng, C-H Pui, M V Relling, W E Evans

Author Affiliations

1: Department of Pharmaceutical Sciences, St Jude Children's Research Hospital, Memphis, Tennessee, USA.

Associated clinical trials:

Therapy for Newly Diagnosed Patients With Acute Lymphoblastic Leukemia | NCT00137111

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