Evaluation of serum CC-16 as a biomarker for COPD in the ECLIPSE cohort.

PubWeight™: 2.25‹?› | Rank: Top 2%

🔗 View Article (PMID 18757456)

Published in Thorax on August 29, 2008

Authors

D A Lomas1, E K Silverman, L D Edwards, B E Miller, H O Coxson, R Tal-Singer, Evaluation of COPD Longitudinally to Identify Predictive Surrogate Endpoints (ECLIPSE) investigators

Author Affiliations

1: Department of Medicine, University of Cambridge, Cambridge Institute for Medical Research, Wellcome Trust/MRC Building, Hills Road, Cambridge CB2 0XY, UK. dal16@cam.ac.uk

Associated clinical trials:

Evaluation of COPD (Chronic Obstructive Pulmonary Disease) to Longitudinally Identify Predictive Surrogate Endpoints (ECLIPSE) | NCT00292552

Articles citing this

Club cell protein 16 and disease progression in chronic obstructive pulmonary disease. Am J Respir Crit Care Med (2013) 2.82

Genome-wide association analysis of blood biomarkers in chronic obstructive pulmonary disease. Am J Respir Crit Care Med (2012) 1.72

Relation between circulating CC16 concentrations, lung function, and development of chronic obstructive pulmonary disease across the lifespan: a prospective study. Lancet Respir Med (2015) 1.65

Serum concentrations of club cell secretory protein (Clara) and cancer mortality in adults: a population-based, prospective cohort study. Lancet Respir Med (2013) 1.58

Protective role for club cell secretory protein-16 (CC16) in the development of COPD. Eur Respir J (2015) 1.50

COPD association and repeatability of blood biomarkers in the ECLIPSE cohort. Respir Res (2011) 1.43

RNA-Seq quantification of the human small airway epithelium transcriptome. BMC Genomics (2012) 1.28

Variable DNA methylation is associated with chronic obstructive pulmonary disease and lung function. Am J Respir Crit Care Med (2011) 1.26

Serum PARC/CCL-18 concentrations and health outcomes in chronic obstructive pulmonary disease. Am J Respir Crit Care Med (2011) 1.23

Blood fibrinogen as a biomarker of chronic obstructive pulmonary disease. Thorax (2012) 1.23

The role of matrix metalloproteinase-9 in cigarette smoke-induced emphysema. Am J Respir Crit Care Med (2010) 1.16

Genetics of sputum gene expression in chronic obstructive pulmonary disease. PLoS One (2011) 1.11

Inflammatory and repair serum biomarker pattern: association to clinical outcomes in COPD. Respir Res (2012) 1.07

Systemic biomarkers of neutrophilic inflammation, tissue injury and repair in COPD patients with differing levels of disease severity. PLoS One (2012) 1.03

Macrophage chitinase 1 stratifies chronic obstructive lung disease. Am J Respir Cell Mol Biol (2009) 1.02

Airway inflammation in Japanese COPD patients compared with smoking and nonsmoking controls. Int J Chron Obstruct Pulmon Dis (2015) 0.96

Measurement of MMP-9 and -12 degraded elastin (ELM) provides unique information on lung tissue degradation. BMC Pulm Med (2012) 0.94

Novel outcomes and end points: biomarkers in chronic obstructive pulmonary disease clinical trials. Proc Am Thorac Soc (2011) 0.92

Inhaled LPS challenges in smokers: a study of pulmonary and systemic effects. Br J Clin Pharmacol (2012) 0.88

Biomarkers and bacterial pneumonia risk in patients with treated HIV infection: a case-control study. PLoS One (2013) 0.86

Trachea epithelium as a "canary" for cigarette smoking-induced biologic phenotype of the small airway epithelium. Clin Transl Sci (2009) 0.84

Characterization of the inflammatory response to inhaled lipopolysaccharide in mild to moderate chronic obstructive pulmonary disease. Br J Clin Pharmacol (2015) 0.82

Budesonide/formoterol enhances the expression of pro Surfactant Protein-B in lungs of COPD patients. PLoS One (2013) 0.82

Urine Club Cell 16-kDa Secretory Protein and Childhood Wheezing Illnesses After Lower Respiratory Tract Infections in Infancy. Pediatr Allergy Immunol Pulmonol (2015) 0.80

Surfactant protein D, Club cell protein 16, Pulmonary and activation-regulated chemokine, C-reactive protein, and Fibrinogen biomarker variation in chronic obstructive lung disease. Respir Res (2014) 0.79

Identification of lung-specific genes by meta-analysis of multiple tissue RNA-seq data. FEBS Open Bio (2016) 0.79

Repression of CC16 by cigarette smoke (CS) exposure. PLoS One (2015) 0.79

Biomarkers in airway diseases. Can Respir J (2013) 0.79

Susceptibility to COPD: differential proteomic profiling after acute smoking. PLoS One (2014) 0.78

COPD and biomarkers: the search goes on. Thorax (2008) 0.78

Mass casualties and health care following the release of toxic chemicals or radioactive material--contribution of modern biotechnology. Int J Environ Res Public Health (2011) 0.77

Biomarkers of lung injury in cardiothoracic surgery. Dis Markers (2015) 0.77

Responsiveness of blood and sputum inflammatory cells in Japanese COPD patients, non-COPD smoking controls, and non-COPD nonsmoking controls. Int J Chron Obstruct Pulmon Dis (2016) 0.77

Challenges and Current Efforts in the Development of Biomarkers for Chronic Inflammatory and Remodeling Conditions of the Lungs. Biomark Insights (2016) 0.76

Club Cell Protein 16 (CC16) Augmentation: A Potential Disease-modifying Approach for Chronic Obstructive Pulmonary Disease (COPD). Expert Opin Ther Targets (2016) 0.76

Functional capacity, health status, and inflammatory biomarker profile in a cohort of patients with chronic obstructive pulmonary disease. J Cardiopulm Rehabil Prev (2015) 0.76

Fetuin-B (FETUB): a Plasma Biomarker Candidate Related to the Severity of Lung Function in COPD. Sci Rep (2016) 0.76

Club Cell-16 and RelB as Novel Determinants of Arterial Stiffness in Exacerbating COPD Patients. PLoS One (2016) 0.75

Intraoperative cell salvage during cardiac surgery is associated with reduced postoperative lung injury. Interact Cardiovasc Thorac Surg (2015) 0.75

Role Of Hif2α Oxygen Sensing Pathway In Bronchial Epithelial Club Cell Proliferation. Sci Rep (2016) 0.75

Chronic obstructive pulmonary disease with mild airflow limitation: current knowledge and proposal for future research - a consensus document from six scientific societies. Int J Chron Obstruct Pulmon Dis (2017) 0.75

Articles by these authors

Characterisation of COPD heterogeneity in the ECLIPSE cohort. Respir Res (2010) 5.17

Estimation and tests of haplotype-environment interaction when linkage phase is ambiguous. Hum Hered (2003) 5.06

Evaluation of COPD Longitudinally to Identify Predictive Surrogate End-points (ECLIPSE). Eur Respir J (2008) 4.53

Amplification of inflammation in emphysema and its association with latent adenoviral infection. Am J Respir Crit Care Med (2001) 4.25

The effect of polymorphisms of the beta(2)-adrenergic receptor on the response to regular use of albuterol in asthma. Am J Respir Crit Care Med (2000) 3.08

CD18-dependent and -independent mechanisms of neutrophil emigration in the pulmonary and systemic microcirculation of rabbits. J Immunol (1990) 2.94

Patterns of Growth and Decline in Lung Function in Persistent Childhood Asthma. N Engl J Med (2016) 2.89

Heterogeneity of therapeutic responses in asthma. Br Med Bull (2000) 2.86

Analysis of individual human trigeminal ganglia for latent herpes simplex virus type 1 and varicella-zoster virus nucleic acids using real-time PCR. J Virol (2000) 2.70

Characterization of a highly invasive and spontaneously metastatic human malignant melanoma cell line. Int J Cancer (1991) 2.26

Identification and initial characterization of four novel members of the interleukin-1 family. J Biol Chem (2000) 2.24

Associations of IL6 polymorphisms with lung function decline and COPD. Thorax (2009) 2.00

The role of domestic animals in the epidemiology of plague. II. Antibody to Yersinia pestis in sera of dogs and cats. J Infect Dis (1971) 1.99

Tumor heterogeneity: biological implications and therapeutic consequences. Cancer Metastasis Rev (1983) 1.96

Outbreak of a nosocomial infection with a strain of Proteus rettgeri resistant to many antimicrobials. Am J Clin Pathol (1974) 1.95

Quantifying the extent of emphysema: factors associated with radiologists' estimations and quantitative indices of emphysema severity using the ECLIPSE cohort. Acad Radiol (2011) 1.88

Estimation of lung growth using computed tomography. Eur Respir J (2003) 1.78

High frequency of luteal phase deficiency and anovulation in recreational women runners: blunted elevation in follicle-stimulating hormone observed during luteal-follicular transition. J Clin Endocrinol Metab (1998) 1.77

Characterization of metastatic heterogeneity among subpopulations of a single mouse mammary tumor: heterogeneity in phenotypic stability. Invasion Metastasis (1983) 1.67

Elastase and cathepsin G of human monocytes. Quantification of cellular content, release in response to stimuli, and heterogeneity in elastase-mediated proteolytic activity. J Immunol (1989) 1.67

Ordering patterns and utilization of bacteriologic culture reports. Arch Intern Med (1973) 1.67

Comparison of neutrophil and capillary diameters and their relation to neutrophil sequestration in the lung. J Appl Physiol (1985) (1993) 1.65

Preoperative severity of emphysema predictive of improvement after lung volume reduction surgery: use of CT morphometry. Chest (2000) 1.63

Naturally occurring mutations in the human 5-lipoxygenase gene promoter that modify transcription factor binding and reporter gene transcription. J Clin Invest (1997) 1.63

CTLA4 gene polymorphisms are associated with chronic bronchitis. Eur Respir J (2009) 1.62

Quantitative computed tomography: emphysema and airway wall thickness by sex, age and smoking. Eur Respir J (2009) 1.61

Polymorphisms in the superoxide dismutase-3 gene are associated with emphysema in COPD. COPD (2010) 1.60

Core to rind distribution of severe emphysema predicts outcome of lung volume reduction surgery. Am J Respir Crit Care Med (2001) 1.57

Serum surfactant protein D is steroid sensitive and associated with exacerbations of COPD. Eur Respir J (2009) 1.56

Alpha1-antitrypsin deficiency. 2: genetic aspects of alpha(1)-antitrypsin deficiency: phenotypes and genetic modifiers of emphysema risk. Thorax (2004) 1.55

Bone health is not affected by luteal phase abnormalities and decreased ovarian progesterone production in female runners. J Clin Endocrinol Metab (1997) 1.54

Quantification of skeletal alkaline phosphatase in osteoporotic serum by wheat germ agglutinin precipitation, heat inactivation, and a two-site immunoradiometric assay. Clin Chem (1994) 1.50

Chronic obstructive pulmonary disease in alpha1-antitrypsin PI MZ heterozygotes: a meta-analysis. Thorax (2004) 1.48

Fluticasone alone or in combination with salmeterol vs triamcinolone in asthma. Chest (1999) 1.48

Characterization of the cysJIH regions of Salmonella typhimurium and Escherichia coli B. DNA sequences of cysI and cysH and a model for the siroheme-Fe4S4 active center of sulfite reductase hemoprotein based on amino acid homology with spinach nitrite reductase. J Biol Chem (1989) 1.47

Comparative culture methods on 101 intravenous catheters. Routine, semiquantitative, and blood cultures. Arch Intern Med (1983) 1.47

Impact of non-linear smoking effects on the identification of gene-by-smoking interactions in COPD genetics studies. Thorax (2010) 1.46

Univariate and multivariate family-based association analysis of the IL-13 ARG130GLN polymorphism in the Childhood Asthma Management Program. Genet Epidemiol (2002) 1.46

Characterization of the flavoprotein moieties of NADPH-sulfite reductase from Salmonella typhimurium and Escherichia coli. Physicochemical and catalytic properties, amino acid sequence deduced from DNA sequence of cysJ, and comparison with NADPH-cytochrome P-450 reductase. J Biol Chem (1989) 1.44

EMPHYSEMA QUANTIFICATION IN A MULTI-SCANNER HRCT COHORT USING LOCAL INTENSITY DISTRIBUTIONS. Proc IEEE Int Symp Biomed Imaging (2012) 1.42

Association between a sequence variant in the IL-4 gene promoter and FEV(1) in asthma. Am J Respir Crit Care Med (1999) 1.39

Characterization of domains of herpes simplex virus type 1 glycoprotein E involved in Fc binding activity for immunoglobulin G aggregates. J Virol (1994) 1.36

The epidemiology of 2056 remote site infections and 1966 surgical wound infections occurring in 1865 patients: a four year study of 40,923 operations at Rush-Presbyterian-St. Luke's Hospital, Chicago. Ann Surg (1976) 1.34

The genetics of chronic obstructive pulmonary disease. Respir Res (2001) 1.33

Chronic obstructive pulmonary disease. 1: Susceptibility factors for COPD the genotype-environment interaction. Thorax (2002) 1.31

Purification of the cysB protein from Salmonella typhimurium. J Biol Chem (1987) 1.28

Role of p38 mitogen-activated protein kinase in rhinovirus-induced cytokine production by bronchial epithelial cells. J Immunol (2000) 1.25

Macrophage-mediated induction of drug-resistant variants in a mouse mammary tumor cell line. Cancer Res (1986) 1.20

Computed tomographic imaging of the airways: relationship to structure and function. Eur Respir J (2005) 1.20

Herpes simplex virus type 1 glycoprotein E domains involved in virus spread and disease. J Virol (2000) 1.19

Effect of polymorphism of the beta(2)-adrenergic receptor on response to regular use of albuterol in asthma. Int Arch Allergy Immunol (2001) 1.18

Computed tomographic estimation of lung dimensions throughout the growth period. Eur Respir J (2006) 1.17

Exhaled nitric oxide in patients with asthma: association with NOS1 genotype. Am J Respir Crit Care Med (2000) 1.16

Smoking related COPD and facial wrinkling: is there a common susceptibility? Thorax (2006) 1.15

Familial aggregation of FEF(25-75) and FEF(25-75)/FVC in families with severe, early onset COPD. Thorax (2004) 1.15

Growth interaction in vivo between tumor subpopulations derived from a single mouse mammary tumor. Cancer Res (1980) 1.14

Quantitation of neutrophil migration in acute bacterial pneumonia in rabbits. J Appl Physiol (1985) (1994) 1.13

Interactions between tumor subpopulations affecting their sensitivity to the antineoplastic agents cyclophosphamide and methotrexate. Cancer Res (1981) 1.13

Lung structure and function in cigarette smokers. Thorax (1994) 1.12

Prediction of the rate of decline in FEV(1) in smokers using quantitative Computed Tomography. Thorax (2009) 1.12

Factors affecting growth and drug sensitivity of mouse mammary tumor lines in collagen gel cultures. Cancer Res (1985) 1.12

Clinical determinants of exacerbations in severe, early-onset COPD. Eur Respir J (2007) 1.11

An antibody that blocks insulin-like growth factor (IGF) binding to the type II IGF receptor is neither an agonist nor an inhibitor of IGF-stimulated biologic responses in L6 myoblasts. J Biol Chem (1987) 1.11

Erythrocyte and polymorphonuclear cell transit time and concentration in human pulmonary capillaries. J Appl Physiol (1985) (1994) 1.10

Enhanced metastatic ability of TNF-alpha-treated malignant melanoma cells is reduced by intercellular adhesion molecule-1 (ICAM-1, CD54) antisense oligonucleotides. Exp Cell Res (1994) 1.09

Spontaneous fusion between metastatic mammary tumor subpopulations. J Cell Biochem (1988) 1.08

Risk of local and systemic infections associated with umbilical vein catheterization: a prospective study in 86 newborn patients. Pediatrics (1971) 1.06

Association of COPD candidate genes with computed tomography emphysema and airway phenotypes in severe COPD. Eur Respir J (2010) 1.06

Therapeutic implications of tumor heterogeneity. Semin Oncol (1989) 1.06

FACS quantitation of leucine aminopeptidase and acid phosphatase on tumor-associated macrophages from metastatic and nonmetastatic mouse mammary tumors. J Leukoc Biol (1985) 1.05

The protease inhibitor PI*S allele and COPD: a meta-analysis. Eur Respir J (2005) 1.04

Coronary artery calcification is increased in patients with COPD and associated with increased morbidity and mortality. Thorax (2014) 1.02

The pharmacokinetics of milrinone in pediatric patients after cardiac surgery. Anesthesiology (1999) 1.00

The African-American Health Project (AAHP): study overview and select findings on high risk behaviors and psychiatric disorders in African American men. Ethn Health (1997) 0.99

Application of an algorithm for the diagnosis of asthma in Chinese families: limitations and alternatives for the phenotypic assessment of asthma in family-based genetic studies. Am J Respir Crit Care Med (2000) 0.99

Use of a glucocorticoid-inducible promoter for expression of herpes simplex virus type 1 glycoprotein gC1, a cytotoxic protein in mammalian cells. Mol Cell Biol (1989) 0.98

Infections and use of antimicrobials in an 800-bed hospital. Public Health Rep (1969) 0.98

Polymorphic variation in surfactant protein B is associated with COPD exacerbations. Eur Respir J (2008) 0.98

Calcium fluxes in isolated acinar cells from rat parotid. Effect of adrenergic and cholinergic stimulation. J Biol Chem (1977) 0.97

Silica-induced hypertrophy of type II cells in the lungs of rats. Lab Invest (1986) 0.97

Risk factors for childhood asthma in Costa Rica. Chest (2001) 0.96

Bronchodilator responsiveness and serum total IgE levels in families of probands with severe early-onset COPD. Eur Respir J (1999) 0.96

Case-control association studies in pharmacogenetics. Pharmacogenomics J (2001) 0.96

Semiquantitative cultures and routine tip cultures on umbilical catheters. J Pediatr (1982) 0.96

Candidate genes for COPD in two large data sets. Eur Respir J (2010) 0.96

Growth regulation of mouse mammary tumor cells in collagen gel cultures by diffusible factors produced by normal mammary gland epithelium and stromal fibroblasts. Cancer Res (1989) 0.95

Quantitation of silica-induced type II cell hyperplasia by using alkaline phosphatase histochemistry in glycol methacrylate embedded lung. Exp Lung Res (1987) 0.95

Differential influence of organ site on three subpopulations of a single mouse mammary tumor at two distinct steps in metastasis. Int J Cancer (1991) 0.94

A comparative study of 48 host valve and 24 prosthetic valve endocarditis cases. Am Heart J (1976) 0.94

Plethysmography and impulse oscillometry assessment of tiotropium and ipratropium bromide; a randomized, double-blind, placebo-controlled, cross-over study in healthy subjects. Br J Clin Pharmacol (2006) 0.92

Bronchiolitis obliterans following lung transplantation: early detection using computed tomographic scanning. Thorax (2006) 0.92

Alkaline phosphatase histochemistry discriminates peritubular cells in primary rat testicular cell culture. J Androl (1987) 0.90

Metabolic cooperation between mouse mammary tumor subpopulations in three-dimensional collagen gel cultures. Cancer Res (1986) 0.89

Physiological and morphological determinants of maximal expiratory flow in chronic obstructive lung disease. Eur Respir J (1996) 0.89