Published in Proc Natl Acad Sci U S A on September 08, 2008
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Interactions between Tau and α-synuclein augment neurotoxicity in a Drosophila model of Parkinson's disease. Hum Mol Genet (2014) 0.95
Cytokine signaling through the JAK/STAT pathway is required for long-term memory in Drosophila. Proc Natl Acad Sci U S A (2011) 0.88
Macrophage-derived upd3 cytokine causes impaired glucose homeostasis and reduced lifespan in Drosophila fed a lipid-rich diet. Immunity (2015) 0.86
A steroid-controlled global switch in sensitivity to apoptosis during Drosophila development. Dev Biol (2013) 0.85
PI3K signaling and Stat92E converge to modulate glial responsiveness to axonal injury. PLoS Biol (2014) 0.83
The BTB-zinc finger transcription factor abrupt acts as an epithelial oncogene in Drosophila melanogaster through maintaining a progenitor-like cell state. PLoS Genet (2013) 0.83
Drosophila Rel proteins are central regulators of a robust, multi-organ immune network. J Cell Sci (2010) 0.83
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Transcription co-activator SAYP mediates the action of STAT activator. Nucleic Acids Res (2011) 0.80
Drosophila Wnt and STAT Define Apoptosis-Resistant Epithelial Cells for Tissue Regeneration after Irradiation. PLoS Biol (2016) 0.76
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Paracrine signaling through the JAK/STAT pathway activates invasive behavior of ovarian epithelial cells in Drosophila. Cell (2001) 2.05
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A protocol for mosaic analysis with a repressible cell marker (MARCM) in Drosophila. Nat Protoc (2006) 1.68
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Opposing roles for Drosophila JAK/STAT signalling during cellular proliferation. Oncogene (2005) 1.16
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Drosophila p53: meeting the Grim Reaper. Nat Cell Biol (2000) 0.89
A comparison of programmed cell death between species. Genome Biol (2000) 0.87
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Apoptotic cells can induce compensatory cell proliferation through the JNK and the Wingless signaling pathways. Dev Cell (2004) 4.71
The JAK-STAT pathway at twenty. Immunity (2012) 4.41
Signal transduction and the control of gene expression. Science (2002) 4.38
Caspase activity and a specific cytochrome C are required for sperm differentiation in Drosophila. Dev Cell (2003) 4.23
Decay rates of human mRNAs: correlation with functional characteristics and sequence attributes. Genome Res (2003) 4.07
Validating Stat3 in cancer therapy. Nat Med (2005) 2.96
Unfolded protein response in a Drosophila model for retinal degeneration. EMBO J (2006) 2.45
Regulation of Drosophila IAP1 degradation and apoptosis by reaper and ubcD1. Nat Cell Biol (2002) 2.42
Structural bases of unphosphorylated STAT1 association and receptor binding. Mol Cell (2005) 2.05
The DIAP1 RING finger mediates ubiquitination of Dronc and is indispensable for regulating apoptosis. Nat Cell Biol (2002) 1.97
A ubiquitin ligase complex regulates caspase activation during sperm differentiation in Drosophila. PLoS Biol (2007) 1.96
Apoptosis, stem cells, and tissue regeneration. Sci Signal (2010) 1.95
The Sept4 septin locus is required for sperm terminal differentiation in mice. Dev Cell (2005) 1.92
Regulation of the Drosophila apoptosome through feedback inhibition. Nat Cell Biol (2008) 1.83
Cyclin D1 is transcriptionally regulated by and required for transformation by activated signal transducer and activator of transcription 3. Cancer Res (2006) 1.69
Implications of an antiparallel dimeric structure of nonphosphorylated STAT1 for the activation-inactivation cycle. Proc Natl Acad Sci U S A (2005) 1.68
Regulation of apoptosis by XIAP ubiquitin-ligase activity. Genes Dev (2008) 1.63
Specificity of Distalless repression and limb primordia development by abdominal Hox proteins. Dev Cell (2002) 1.61
Sept4/ARTS is required for stem cell apoptosis and tumor suppression. Genes Dev (2010) 1.57
Dephosphorylation of phosphotyrosine on STAT1 dimers requires extensive spatial reorientation of the monomers facilitated by the N-terminal domain. Genes Dev (2006) 1.53
ER stress protects from retinal degeneration. EMBO J (2009) 1.47
Regulation of cell number by MAPK-dependent control of apoptosis: a mechanism for trophic survival signaling. Dev Cell (2002) 1.45
Expression of human Gaucher disease gene GBA generates neurodevelopmental defects and ER stress in Drosophila eye. PLoS One (2013) 1.45
The mitochondrial ARTS protein promotes apoptosis through targeting XIAP. EMBO J (2004) 1.42
The two Drosophila cytochrome C proteins can function in both respiration and caspase activation. EMBO J (2005) 1.42
A reinterpretation of the dimerization interface of the N-terminal domains of STATs. Protein Sci (2003) 1.39
IAP-antagonists exhibit non-redundant modes of action through differential DIAP1 binding. EMBO J (2003) 1.38
Independent and cooperative activation of chromosomal c-fos promoter by STAT3. J Biol Chem (2003) 1.32
Ero1L, a thiol oxidase, is required for Notch signaling through cysteine bridge formation of the Lin12-Notch repeats in Drosophila melanogaster. J Cell Biol (2008) 1.32
Dissociation time from DNA determines transcriptional function in a STAT1 linker mutant. J Biol Chem (2002) 1.26
Cytochrome c-d regulates developmental apoptosis in the Drosophila retina. EMBO Rep (2006) 1.26
STAT3-dependent enhanceosome assembly and disassembly: synergy with GR for full transcriptional increase of the alpha 2-macroglobulin gene. Genes Dev (2003) 1.22
Requirement of Ca2+ and CaMKII for Stat1 Ser-727 phosphorylation in response to IFN-gamma. Proc Natl Acad Sci U S A (2002) 1.21
Distinct pathways mediate UV-induced apoptosis in Drosophila embryos. Dev Cell (2003) 1.19
The microtubule-targeting agent CA4P regresses leukemic xenografts by disrupting interaction with vascular cells and mitochondrial-dependent cell death. Blood (2007) 1.17
CDK5 and MEKK1 mediate pro-apoptotic signalling following endoplasmic reticulum stress in an autosomal dominant retinitis pigmentosa model. Nat Cell Biol (2012) 1.17
Suppression of retinal degeneration in Drosophila by stimulation of ER-associated degradation. Proc Natl Acad Sci U S A (2009) 1.15
Regulation of R7 and R8 differentiation by the spalt genes. Dev Biol (2004) 1.13
Unfolded protein response in Drosophila: why another model can make it fly. Cell Cycle (2007) 1.12
Sept4/ARTS regulates stem cell apoptosis and skin regeneration. Science (2013) 1.11
Regulation of cell death by the ubiquitin-proteasome system. Curr Opin Cell Biol (2009) 1.11
Apoptotic cells can induce non-autonomous apoptosis through the TNF pathway. Elife (2013) 1.11
SnapShot: JAK-STAT signaling. Cell (2007) 1.10
Detection of apoptosis by terminal deoxynucleotidyl transferase-mediated dUTP nick-end labeling and acridine orange in Drosophila embryos and adult male gonads. Nat Protoc (2006) 1.10
Distinct transcriptional activation functions of STAT1alpha and STAT1beta on DNA and chromatin templates. J Biol Chem (2003) 1.10
Drosophila IAP antagonists form multimeric complexes to promote cell death. J Cell Biol (2010) 1.09
Xbp1-independent Ire1 signaling is required for photoreceptor differentiation and rhabdomere morphogenesis in Drosophila. Cell Rep (2013) 1.08
Amino acid residues required for physical and cooperative transcriptional interaction of STAT3 and AP-1 proteins c-Jun and c-Fos. Mol Cell Biol (2007) 1.07
Proteasome regulation by ADP-ribosylation. Cell (2013) 1.05
Two-color in vivo imaging of photoreceptor apoptosis and development in Drosophila. Dev Biol (2011) 1.03
Spalt transcription factors are required for R3/R4 specification and establishment of planar cell polarity in the Drosophila eye. Development (2004) 1.01
A modified UPR stress sensing system reveals a novel tissue distribution of IRE1/XBP1 activity during normal Drosophila development. Cell Stress Chaperones (2012) 1.00
Pathways regulating apoptosis during patterning and development. Curr Opin Genet Dev (2007) 0.98
A conserved F box regulatory complex controls proteasome activity in Drosophila. Cell (2011) 0.98
Negative regulation of STAT92E by an N-terminally truncated STAT protein derived from an alternative promoter site. Genes Dev (2002) 0.98
Coupling of apoptosis and L/R patterning controls stepwise organ looping. Curr Biol (2010) 0.96
Impaired tissue growth is mediated by checkpoint kinase 1 (CHK1) in the integrated stress response. J Cell Sci (2010) 0.92
A novel F-box protein is required for caspase activation during cellular remodeling in Drosophila. Development (2010) 0.89
Regulation of the proapoptotic ARTS protein by ubiquitin-mediated degradation. J Biol Chem (2005) 0.89
Drosophila Past1 is involved in endocytosis and is required for germline development and survival of the adult fly. J Cell Sci (2009) 0.89
Serpin B3/B4, activated by STAT3, promote survival of squamous carcinoma cells. Biochem Biophys Res Commun (2008) 0.86
Unfolded protein response in Gaucher disease: from human to Drosophila. Orphanet J Rare Dis (2013) 0.85
Transformation fingerprint: induced STAT3-C, v-Src and Ha-Ras cause small initial changes but similar established profiles in mRNA. Oncogene (2004) 0.83
Hippo and its mission for growth control. Nat Cell Biol (2003) 0.83
A Hopscotch-chromatin connection. Nat Genet (2006) 0.82
Letting go: modification of cell adhesion during apoptosis. J Biol (2009) 0.79
Reduced STAT3 activity in mice mimics clinical disease syndromes. Biochem Biophys Res Commun (2005) 0.78
Thiostrepton, a natural compound that triggers heat shock response and apoptosis in human cancer cells: a proteomics investigation. Adv Exp Med Biol (2014) 0.77
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Another tier for caspase regulation: IAPs as NEDD8 E3 ligases. Dev Cell (2010) 0.76
Correction: Expression of Human Gaucher Disease Gene GBA Generates Neurodevelopmental Defects and ER Stress in Drosophila Eye. PLoS One (2015) 0.75
A gain-of-function germline mutation in Drosophila ras1 affects apoptosis and cell fate during development. PLoS One (2011) 0.75
Hyung Don Ryoo: a healthy career in cellular death. J Cell Biol (2009) 0.75
Pro-apoptotic signaling pathway by CDK5 and MEKK1. Cell Cycle (2012) 0.75
Correction: Past1 Modulates Drosophila Eye Development. PLoS One (2017) 0.75
Obituary: Hidesaburo Hanafusa (1929-2009). Nature (2009) 0.75
Preface. Curr Top Dev Biol (2015) 0.75