PubRank

Jane Worthington

Author PubWeight™ 229.09‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Association scan of 14,500 nonsynonymous SNPs in four diseases identifies autoimmunity variants. Nat Genet 2007 12.62
2 Genome-wide association study of CNVs in 16,000 cases of eight common diseases and 3,000 shared controls. Nature 2010 12.27
3 Genome-wide association study meta-analysis identifies seven new rheumatoid arthritis risk loci. Nat Genet 2010 9.90
4 Meta-analysis and imputation refines the association of 15q25 with smoking quantity. Nat Genet 2010 8.55
5 A genome-wide association study identifies new psoriasis susceptibility loci and an interaction between HLA-C and ERAP1. Nat Genet 2010 8.48
6 Common variants at CD40 and other loci confer risk of rheumatoid arthritis. Nat Genet 2008 7.07
7 Rheumatoid arthritis association at 6q23. Nat Genet 2007 6.71
8 A genome-wide association study of psoriasis and psoriatic arthritis identifies new disease loci. PLoS Genet 2008 5.85
9 Five amino acids in three HLA proteins explain most of the association between MHC and seropositive rheumatoid arthritis. Nat Genet 2012 5.11
10 Whole-genome scan, in a complex disease, using 11,245 single-nucleotide polymorphisms: comparison with microsatellites. Am J Hum Genet 2004 4.76
11 High-density genetic mapping identifies new susceptibility loci for rheumatoid arthritis. Nat Genet 2012 4.46
12 Pervasive sharing of genetic effects in autoimmune disease. PLoS Genet 2011 4.42
13 Bayesian inference analyses of the polygenic architecture of rheumatoid arthritis. Nat Genet 2012 4.41
14 Identification of 15 new psoriasis susceptibility loci highlights the role of innate immunity. Nat Genet 2012 4.13
15 Whole-genome linkage analysis of rheumatoid arthritis susceptibility loci in 252 affected sibling pairs in the United Kingdom. Arthritis Rheum 2002 3.78
16 Meta-analysis of genome-wide association studies in celiac disease and rheumatoid arthritis identifies fourteen non-HLA shared loci. PLoS Genet 2011 3.68
17 Genetic variants at CD28, PRDM1 and CD2/CD58 are associated with rheumatoid arthritis risk. Nat Genet 2009 3.52
18 Bayesian refinement of association signals for 14 loci in 3 common diseases. Nat Genet 2012 3.31
19 Rheumatoid arthritis susceptibility loci at chromosomes 10p15, 12q13 and 22q13. Nat Genet 2008 3.18
20 Association between the PTPN22 gene and rheumatoid arthritis and juvenile idiopathic arthritis in a UK population: further support that PTPN22 is an autoimmunity gene. Arthritis Rheum 2005 2.93
21 Genome-wide association study of systemic sclerosis identifies CD247 as a new susceptibility locus. Nat Genet 2010 2.61
22 Identification of ZNF313/RNF114 as a novel psoriasis susceptibility gene. Hum Mol Genet 2008 2.42
23 Meta-analysis identifies nine new loci associated with rheumatoid arthritis in the Japanese population. Nat Genet 2012 2.31
24 Rheumatoid arthritis risk allele PTPRC is also associated with response to anti-tumor necrosis factor alpha therapy. Arthritis Rheum 2010 2.08
25 Re-evaluation of putative rheumatoid arthritis susceptibility genes in the post-genome wide association study era and hypothesis of a key pathway underlying susceptibility. Hum Mol Genet 2008 2.08
26 Investigation of genetic variation across the protein tyrosine phosphatase gene in patients with rheumatoid arthritis in the UK. Ann Rheum Dis 2006 1.99
27 Reevaluation of the interaction between HLA-DRB1 shared epitope alleles, PTPN22, and smoking in determining susceptibility to autoantibody-positive and autoantibody-negative rheumatoid arthritis in a large UK Caucasian population. Arthritis Rheum 2009 1.95
28 Overlapping genetic susceptibility variants between three autoimmune disorders: rheumatoid arthritis, type 1 diabetes and coeliac disease. Arthritis Res Ther 2010 1.85
29 Identification of novel genetic markers associated with clinical phenotypes of systemic sclerosis through a genome-wide association strategy. PLoS Genet 2011 1.80
30 Quantitative heritability of anti-citrullinated protein antibody-positive and anti-citrullinated protein antibody-negative rheumatoid arthritis. Arthritis Rheum 2009 1.80
31 A functional haplotype of the PADI4 gene associated with rheumatoid arthritis in a Japanese population is not associated in a United Kingdom population. Arthritis Rheum 2004 1.79
32 EULAR recommendations for terminology and research in individuals at risk of rheumatoid arthritis: report from the Study Group for Risk Factors for Rheumatoid Arthritis. Ann Rheum Dis 2012 1.78
33 Informed conditioning on clinical covariates increases power in case-control association studies. PLoS Genet 2012 1.57
34 Identification of AF4/FMR2 family, member 3 (AFF3) as a novel rheumatoid arthritis susceptibility locus and confirmation of two further pan-autoimmune susceptibility genes. Hum Mol Genet 2009 1.55
35 Use of a multiethnic approach to identify rheumatoid- arthritis-susceptibility loci, 1p36 and 17q12. Am J Hum Genet 2012 1.46
36 Polymorphisms in the IL-12beta and IL-23R genes are associated with psoriasis of early onset in a UK cohort. J Invest Dermatol 2007 1.44
37 Combined effects of three independent SNPs greatly increase the risk estimate for RA at 6q23. Hum Mol Genet 2009 1.37
38 Data for Genetic Analysis Workshop (GAW) 15 Problem 2, genetic causes of rheumatoid arthritis and associated traits. BMC Proc 2007 1.36
39 Study of the common genetic background for rheumatoid arthritis and systemic lupus erythematosus. Ann Rheum Dis 2010 1.36
40 Rare, low-frequency, and common variants in the protein-coding sequence of biological candidate genes from GWASs contribute to risk of rheumatoid arthritis. Am J Hum Genet 2012 1.35
41 Protective effect of noninherited maternal HLA-DR antigens on rheumatoid arthritis development. Proc Natl Acad Sci U S A 2007 1.29
42 Investigation of association of the IL12B and IL23R genes with psoriatic arthritis. Arthritis Rheum 2008 1.28
43 Whole-genome screening for susceptibility genes in multicase families with Behçet's disease. Arthritis Rheum 2005 1.27
44 Investigation of potential non-HLA rheumatoid arthritis susceptibility loci in a European cohort increases the evidence for nine markers. Ann Rheum Dis 2010 1.25
45 A GWAS follow-up study reveals the association of the IL12RB2 gene with systemic sclerosis in Caucasian populations. Hum Mol Genet 2011 1.24
46 Association of the IL2RA/CD25 gene with juvenile idiopathic arthritis. Arthritis Rheum 2009 1.23
47 Identification of CSK as a systemic sclerosis genetic risk factor through Genome Wide Association Study follow-up. Hum Mol Genet 2012 1.17
48 The shared epitope hypothesis in rheumatoid arthritis: evaluation of alternative classification criteria in a large UK Caucasian cohort. Arthritis Rheum 2008 1.16
49 Evidence for common genetic control in pathways of inflammation for Crohn's disease and psoriatic arthritis. Arthritis Rheum 2005 1.16
50 Association of the tumour necrosis factor-308 variant with differential response to anti-TNF agents in the treatment of rheumatoid arthritis. Hum Mol Genet 2008 1.16
51 Use of gene expression profiling to identify a novel glucocorticoid sensitivity determining gene, BMPRII. FASEB J 2006 1.15
52 Genetic markers of rheumatoid arthritis susceptibility in anti-citrullinated peptide antibody negative patients. Ann Rheum Dis 2012 1.14
53 Overlap of disease susceptibility loci for rheumatoid arthritis and juvenile idiopathic arthritis. Ann Rheum Dis 2009 1.10
54 Identification of a novel susceptibility locus for juvenile idiopathic arthritis by genome-wide association analysis. Arthritis Rheum 2009 1.09
55 HLA-Cw6 and HLA-DRB1*07 together are associated with less severe joint disease in psoriatic arthritis. Ann Rheum Dis 2007 1.08
56 Association of CD40 with rheumatoid arthritis confirmed in a large UK case-control study. Ann Rheum Dis 2009 1.07
57 PADI4 genotype is not associated with rheumatoid arthritis in a large UK Caucasian population. Ann Rheum Dis 2009 1.06
58 A replication study confirms the association of TNFSF4 (OX40L) polymorphisms with systemic sclerosis in a large European cohort. Ann Rheum Dis 2010 1.05
59 Investigation of the SLC22A4 gene (associated with rheumatoid arthritis in a Japanese population) in a United Kingdom population of rheumatoid arthritis patients. Arthritis Rheum 2005 1.04
60 Genetic susceptibility to rheumatoid arthritis: an emerging picture. Arthritis Rheum 2009 1.04
61 Investigation of rheumatoid arthritis susceptibility loci in juvenile idiopathic arthritis confirms high degree of overlap. Ann Rheum Dis 2012 1.01
62 The distribution of the endogenous retroviruses HERV-K113 and HERV-K115 in health and disease. Genomics 2005 1.00
63 Investigation of rheumatoid arthritis genetic susceptibility markers in the early rheumatoid arthritis study further replicates the TRAF1 association with radiological damage. J Rheumatol 2012 0.98
64 The role of rheumatoid arthritis genetic susceptibility markers in the prediction of erosive disease in patients with early inflammatory polyarthritis: results from the Norfolk Arthritis Register. Rheumatology (Oxford) 2010 0.98
65 Evaluation of the rheumatoid arthritis susceptibility loci HLA-DRB1, PTPN22, OLIG3/TNFAIP3, STAT4 and TRAF1/C5 in an inception cohort. Arthritis Res Ther 2010 0.98
66 Investigation of susceptibility loci identified in the UK rheumatoid arthritis whole-genome scan in a further series of 217 UK affected sibling pairs. Arthritis Rheum 2004 0.97
67 Genetic epidemiology of rheumatoid arthritis. Curr Opin Rheumatol 2006 0.97
68 Predicting the risk of rheumatoid arthritis and its age of onset through modelling genetic risk variants with smoking. PLoS Genet 2013 0.96
69 Evidence to support IL-13 as a risk locus for psoriatic arthritis but not psoriasis vulgaris. Ann Rheum Dis 2011 0.96
70 Macrophage migration inhibitory factor gene polymorphism is associated with psoriasis. J Invest Dermatol 2004 0.96
71 Haplotype analysis in simplex families and novel analytic approaches in a case-control cohort reveal no evidence of association of the CTLA-4 gene with rheumatoid arthritis. Arthritis Rheum 2004 0.95
72 A systemic sclerosis and systemic lupus erythematosus pan-meta-GWAS reveals new shared susceptibility loci. Hum Mol Genet 2013 0.94
73 New data and an old puzzle: the negative association between schizophrenia and rheumatoid arthritis. Int J Epidemiol 2015 0.93
74 Human genetics in rheumatoid arthritis guides a high-throughput drug screen of the CD40 signaling pathway. PLoS Genet 2013 0.93
75 Subtype specific genetic associations for juvenile idiopathic arthritis: ERAP1 with the enthesitis related arthritis subtype and IL23R with juvenile psoriatic arthritis. Arthritis Res Ther 2011 0.93
76 Linkage analysis of rheumatoid arthritis in US and UK families reveals interactions between HLA-DRB1 and loci on chromosomes 6q and 16p. Arthritis Rheum 2006 0.92
77 Association of DRD4 in children with ADHD and comorbid conduct problems. Am J Med Genet 2002 0.92
78 The dinucleotide (CA) repeat polymorphism of estrogen receptor beta but not the dinucleotide (TA) repeat polymorphism of estrogen receptor alpha is associated with venous ulceration. J Steroid Biochem Mol Biol 2005 0.92
79 Investigation of association between the TRAF family genes and RA susceptibility. Ann Rheum Dis 2007 0.92
80 Apolipoprotein E genotype does not predict decline in intelligence in healthy older adults. Neurosci Lett 2002 0.91
81 Investigation of genetic variants within candidate genes of the TNFRSF1B signalling pathway on the response to anti-TNF agents in a UK cohort of rheumatoid arthritis patients. Pharmacogenet Genomics 2009 0.91
82 The systemic lupus erythematosus IRF5 risk haplotype is associated with systemic sclerosis. PLoS One 2013 0.91
83 Functional variants of Fc gamma receptor (FCGR2A) and FCGR3A are not associated with susceptibility to systemic sclerosis in a large European Study (EUSTAR). J Rheumatol 2010 0.90
84 Investigation of type 1 diabetes and coeliac disease susceptibility loci for association with juvenile idiopathic arthritis. Ann Rheum Dis 2010 0.90
85 Genetic variation in efflux transporters influences outcome to methotrexate therapy in patients with psoriasis. J Invest Dermatol 2008 0.90
86 Confirmation of TNIP1 but not RHOB and PSORS1C1 as systemic sclerosis risk factors in a large independent replication study. Ann Rheum Dis 2012 0.89
87 Investigation of the MHC2TA gene, associated with rheumatoid arthritis in a Swedish population, in a UK rheumatoid arthritis cohort. Arthritis Rheum 2006 0.89
88 Additional genetic susceptibility for rheumatoid arthritis telomeric of the DRB1 locus. Arthritis Rheum 2004 0.88
89 Influence of the IL6 gene in susceptibility to systemic sclerosis. J Rheumatol 2012 0.88
90 Confirmation of association of the macrophage migration inhibitory factor gene with systemic sclerosis in a large European population. Rheumatology (Oxford) 2011 0.88
91 Identification of BACH2 and RAD51B as rheumatoid arthritis susceptibility loci in a meta-analysis of genome-wide data. Arthritis Rheum 2013 0.88
92 Expression of the autoimmunity associated TNFAIP3 is increased in rheumatoid arthritis but does not differ according to genotype at 6q23. Rheumatology (Oxford) 2012 0.87
93 Identification of the tyrosine-protein phosphatase non-receptor type 2 as a rheumatoid arthritis susceptibility locus in europeans. PLoS One 2013 0.86
94 The CX3CL1-CX3CR1 system and psoriasis. Exp Dermatol 2006 0.86
95 Evidence for a novel rheumatoid arthritis susceptibility locus on chromosome 6p. Arthritis Rheum 2004 0.86
96 Rare variation at the TNFAIP3 locus and susceptibility to rheumatoid arthritis. Hum Genet 2010 0.85
97 Novel rheumatoid arthritis susceptibility locus at 22q12 identified in an extended UK genome-wide association study. Arthritis Rheumatol 2014 0.85
98 Association of a non-synonymous functional variant of the ITGAM gene with systemic sclerosis. Ann Rheum Dis 2011 0.85
99 Characterisation of the genomic architecture of human chromosome 17q and evaluation of different methods for haplotype block definition. BMC Genet 2005 0.84
100 Confirmation of association of the REL locus with rheumatoid arthritis susceptibility in the UK population. Ann Rheum Dis 2009 0.84
101 Genetic susceptibility to psoriasis: an emerging picture. Genome Med 2009 0.84
102 Genetic variation in CCR5 does not predict clinical outcome in inflammatory arthritis. Arthritis Rheum 2003 0.84
103 Interaction analysis between HLA-DRB1 shared epitope alleles and MHC class II transactivator CIITA gene with regard to risk of rheumatoid arthritis. PLoS One 2012 0.84
104 Relationship between area-level socio-economic deprivation and autoantibody status in patients with rheumatoid arthritis: multicentre cross-sectional study. Ann Rheum Dis 2012 0.84
105 Polymorphisms in IGF-binding protein 1 are associated with impaired renal function in type 2 diabetes. Diabetes 2005 0.83
106 Polymorphisms in the mannose binding lectin (MBL) gene are not associated with radiographic erosions in rheumatoid or inflammatory polyarthritis. J Rheumatol 2004 0.83
107 Implication of IL-2/IL-21 region in systemic sclerosis genetic susceptibility. Ann Rheum Dis 2012 0.83
108 Genetic epidemiology of psoriatic arthritis. Mod Rheumatol 2004 0.81
109 New insight on the Xq28 association with systemic sclerosis. Ann Rheum Dis 2013 0.81
110 Fine mapping of genes within the IDDM8 region in rheumatoid arthritis. Arthritis Res Ther 2006 0.81
111 Investigating the viability of genetic screening/testing for RA susceptibility using combinations of five confirmed risk loci. Rheumatology (Oxford) 2009 0.81
112 Association of the FCRL3 gene with rheumatoid arthritis: a further example of population specificity? Arthritis Res Ther 2006 0.80
113 Genetic epidemiology: systemic sclerosis. Arthritis Res 2002 0.80
114 A genome-wide association study follow-up suggests a possible role for PPARG in systemic sclerosis susceptibility. Arthritis Res Ther 2014 0.80
115 No association between polymorphisms in the interleukin-15 gene and early-onset psoriasis in a UK cohort suggests heterogeneity for this susceptibility locus identified in Chinese psoriasis patients. J Invest Dermatol 2008 0.80
116 TNFR2 is not associated with rheumatoid arthritis susceptibility in a Caucasian population. Arthritis Rheum 2005 0.78
117 No evidence of association of two 5HT transporter gene polymorphisms and attention deficit hyperactivity disorder. Psychiatr Genet 2003 0.78
118 Metaanalysis of the association of smoking and PTPN22 R620W genotype on autoantibody status and radiological erosions in rheumatoid arthritis. J Rheumatol 2013 0.78
119 Identification of IL12RB1 as a novel systemic sclerosis susceptibility locus. Arthritis Rheumatol 2014 0.78
120 Association of familial and sporadic rheumatoid arthritis with a single corticotropin-releasing hormone genomic region (8q12.3) haplotype. Arthritis Rheum 2002 0.78
121 Polymorphisms in COL15 gene are not associated with systemic sclerosis. J Rheumatol 2008 0.77
122 No evidence for association of the KLF12 gene with rheumatoid arthritis in a large UK cohort. Ann Rheum Dis 2009 0.76
123 Genotype at the sIL-6R A358C polymorphism does not influence response to anti-TNF therapy in patients with rheumatoid arthritis. Rheumatology (Oxford) 2009 0.76
124 Polymorphisms in the interleukin 4, interleukin 13, and corresponding receptor genes are not associated with systemic sclerosis and do not influence gene expression. J Rheumatol 2011 0.76
125 No evidence of association between HLA-DRB1 and attention deficit hyperactivity disorder. Psychiatr Genet 2003 0.76
126 Linkage analysis of cross-sectional and longitudinally derived phenotypic measures to identify loci influencing blood pressure. BMC Genet 2003 0.75
127 Corrigendum: Statistical colocalization of genetic risk variants for related autoimmune diseases in the context of common controls. Nat Genet 2015 0.75
128 KCNA5 gene is not confirmed as a systemic sclerosis-related pulmonary arterial hypertension genetic susceptibility factor. Arthritis Res Ther 2012 0.75
129 Investigation of association of the DLG5 gene with psoriatic arthritis. Ann Rheum Dis 2007 0.75
130 Commentary on "Genetic linkage and transmission disequilibrium of marker haplotypes at chromosome 1q41 in human systemic lupus erythematosus", by RR Graham et al. Arthritis Res 2001 0.75
131 An MIF Promoter Polymorphism Is Associated with Susceptibility to Pulmonary Arterial Hypertension in Diffuse Cutaneous Systemic Sclerosis. J Rheumatol 2017 0.75
132 Rheumatoid arthritis-associated polymorphisms at 6q23 are associated with radiological damage in autoantibody-positive RA. J Rheumatol 2012 0.75