Evidence that the bulge region is a site of relative immune privilege in human hair follicles.

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🔗 View Article (PMID 18795933)

Published in Br J Dermatol on September 15, 2008

Authors

K C Meyer1, J E Klatte, H V Dinh, M J Harries, K Reithmayer, W Meyer, R Sinclair, R Paus

Author Affiliations

1: Department of Dermatology, Allergology and Venereology, University of Lübeck, Ratzeburger Allee 160, D-23538 Lübeck, Germany.

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Multivisceral resection of advanced colorectal carcinoma. Langenbecks Arch Surg (1999) 1.19

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Comparison of use of phenotypic and genotypic characteristics for identification of species of the anamorph genus Candida and related teleomorph yeast species. J Clin Microbiol (1997) 1.12

Immunity to equine influenza: relationship of vaccine-induced antibody in young Thoroughbred racehorses to protection against field infection with influenza A/equine-2 viruses (H3N8). Equine Vet J (2000) 1.12

Empirically supported ethical research practice: the costs and benefits of research from the participants' view. Account Res (2001) 1.11

Global VGIIa isolates are of comparable virulence to the major fatal Cryptococcus gattii Vancouver Island outbreak genotype. Clin Microbiol Infect (2011) 1.10

Lignin peroxidase H2 from Phanerochaete chrysosporium: purification, characterization and stability to temperature and pH. Arch Biochem Biophys (1990) 1.10