Published in RNA on September 29, 2008
Experimental strategies for microRNA target identification. Nucleic Acids Res (2011) 3.00
A quantitative targeted proteomics approach to validate predicted microRNA targets in C. elegans. Nat Methods (2010) 1.82
miR-107 regulates granulin/progranulin with implications for traumatic brain injury and neurodegenerative disease. Am J Pathol (2010) 1.54
Anti-Argonaute RIP-Chip shows that miRNA transfections alter global patterns of mRNA recruitment to microribonucleoprotein complexes. RNA (2009) 1.45
West Nile virus encodes a microRNA-like small RNA in the 3' untranslated region which up-regulates GATA4 mRNA and facilitates virus replication in mosquito cells. Nucleic Acids Res (2011) 1.44
Tandem affinity purification of miRNA target mRNAs (TAP-Tar). Nucleic Acids Res (2009) 1.32
Survey of Computational Algorithms for MicroRNA Target Prediction. Curr Genomics (2009) 1.31
Specific sequence determinants of miR-15/107 microRNA gene group targets. Nucleic Acids Res (2011) 1.08
Individual microRNAs (miRNAs) display distinct mRNA targeting "rules". RNA Biol (2010) 1.04
MicroRNA-510 promotes cell and tumor growth by targeting peroxiredoxin1 in breast cancer. Breast Cancer Res (2013) 1.03
Isolation and identification of cell-specific microRNAs targeting a messenger RNA using a biotinylated anti-sense oligonucleotide capture affinity technique. Nucleic Acids Res (2013) 0.92
Regulation of the C. elegans molt by pqn-47. Dev Biol (2011) 0.90
Novel miR390-dependent transacting siRNA precursors in plants revealed by a PCR-based experimental approach and database analysis. J Biomed Biotechnol (2009) 0.88
High-throughput experimental studies to identify miRNA targets directly, with special focus on the mammalian brain. Brain Res (2010) 0.86
Integrative miRNA and Gene Expression Profiling Analysis of Human Quiescent Hepatic Stellate Cells. Sci Rep (2015) 0.84
Tiny giants of gene regulation: experimental strategies for microRNA functional studies. Wiley Interdiscip Rev Dev Biol (2016) 0.80
Bioinformatics analysis identify novel OB fold protein coding genes in C. elegans. PLoS One (2013) 0.77
A whole-mount in situ hybridization method for microRNA detection in Caenorhabditis elegans. RNA (2016) 0.75
MicroRNAs: genomics, biogenesis, mechanism, and function. Cell (2004) 198.59
The C. elegans heterochronic gene lin-4 encodes small RNAs with antisense complementarity to lin-14. Cell (1993) 64.62
Prediction of mammalian microRNA targets. Cell (2003) 53.70
Combinatorial microRNA target predictions. Nat Genet (2005) 50.48
Microarray analysis shows that some microRNAs downregulate large numbers of target mRNAs. Nature (2005) 48.95
Identification of novel genes coding for small expressed RNAs. Science (2001) 44.44
An abundant class of tiny RNAs with probable regulatory roles in Caenorhabditis elegans. Science (2001) 44.16
The 21-nucleotide let-7 RNA regulates developmental timing in Caenorhabditis elegans. Nature (2000) 39.31
miRBase: tools for microRNA genomics. Nucleic Acids Res (2007) 38.61
An extensive class of small RNAs in Caenorhabditis elegans. Science (2001) 34.17
Posttranscriptional regulation of the heterochronic gene lin-14 by lin-4 mediates temporal pattern formation in C. elegans. Cell (1993) 33.79
RAS is regulated by the let-7 microRNA family. Cell (2005) 30.24
Ensembl 2008. Nucleic Acids Res (2007) 20.67
Zebrafish MiR-430 promotes deadenylation and clearance of maternal mRNAs. Science (2006) 18.14
The microRNAs of Caenorhabditis elegans. Genes Dev (2003) 17.70
Expression profiling reveals off-target gene regulation by RNAi. Nat Biotechnol (2003) 16.63
The diverse functions of microRNAs in animal development and disease. Dev Cell (2006) 15.62
Regulation by let-7 and lin-4 miRNAs results in target mRNA degradation. Cell (2005) 15.26
Large-scale sequencing reveals 21U-RNAs and additional microRNAs and endogenous siRNAs in C. elegans. Cell (2006) 15.12
Small non-coding RNAs in animal development. Nat Rev Mol Cell Biol (2008) 12.35
The lin-41 RBCC gene acts in the C. elegans heterochronic pathway between the let-7 regulatory RNA and the LIN-29 transcription factor. Mol Cell (2000) 10.92
microRNA target predictions in animals. Nat Genet (2006) 10.76
Discovering microRNAs from deep sequencing data using miRDeep. Nat Biotechnol (2008) 10.17
A genome-wide map of conserved microRNA targets in C. elegans. Curr Biol (2006) 10.14
MicroRNAs and other tiny endogenous RNAs in C. elegans. Curr Biol (2003) 9.90
Intronic microRNA precursors that bypass Drosha processing. Nature (2007) 9.65
The C. elegans microRNA let-7 binds to imperfect let-7 complementary sites from the lin-41 3'UTR. Genes Dev (2004) 8.42
Perfect seed pairing is not a generally reliable predictor for miRNA-target interactions. Nat Struct Mol Biol (2006) 7.97
Widespread siRNA "off-target" transcript silencing mediated by seed region sequence complementarity. RNA (2006) 7.06
3' UTR seed matches, but not overall identity, are associated with RNAi off-targets. Nat Methods (2006) 6.96
The Caenorhabditis elegans hunchback-like gene lin-57/hbl-1 controls developmental time and is regulated by microRNAs. Dev Cell (2003) 6.86
The C elegans hunchback homolog, hbl-1, controls temporal patterning and is a probable microRNA target. Dev Cell (2003) 6.74
Large-scale analysis of gene function in Caenorhabditis elegans by high-throughput RNAi. Curr Biol (2001) 6.05
Isolation of microRNA targets by miRNP immunopurification. RNA (2007) 5.50
Most Caenorhabditis elegans microRNAs are individually not essential for development or viability. PLoS Genet (2007) 5.33
A bulged lin-4/lin-14 RNA duplex is sufficient for Caenorhabditis elegans lin-14 temporal gradient formation. Genes Dev (1996) 5.27
Computational and experimental identification of C. elegans microRNAs. Mol Cell (2003) 5.22
A biochemical approach to identifying microRNA targets. Proc Natl Acad Sci U S A (2007) 5.16
Short interfering RNAs can induce unexpected and divergent changes in the levels of untargeted proteins in mammalian cells. Proc Natl Acad Sci U S A (2004) 4.85
Systematic identification of C. elegans miRISC proteins, miRNAs, and mRNA targets by their interactions with GW182 proteins AIN-1 and AIN-2. Mol Cell (2007) 4.22
The time of appearance of the C. elegans let-7 microRNA is transcriptionally controlled utilizing a temporal regulatory element in its promoter. Dev Biol (2003) 3.92
Specificity of short interfering RNA determined through gene expression signatures. Proc Natl Acad Sci U S A (2003) 3.74
WormBase 2007. Nucleic Acids Res (2007) 3.69
Molecular architecture of a miRNA-regulated 3' UTR. RNA (2008) 3.11
The temporal patterning microRNA let-7 regulates several transcription factors at the larval to adult transition in C. elegans. Dev Cell (2005) 2.81
The timing of lin-4 RNA accumulation controls the timing of postembryonic developmental events in Caenorhabditis elegans. Dev Biol (1999) 2.59
Patterns of flanking sequence conservation and a characteristic upstream motif for microRNA gene identification. RNA (2004) 2.17
The mir-84 and let-7 paralogous microRNA genes of Caenorhabditis elegans direct the cessation of molting via the conserved nuclear hormone receptors NHR-23 and NHR-25. Development (2006) 1.86
Post-embryonic expression of C. elegans microRNAs belonging to the lin-4 and let-7 families in the hypodermis and the reproductive system. Dev Dyn (2005) 1.66
A novel method to detect functional microRNA targets. J Mol Biol (2006) 1.11
Caenorhabditis elegans T-box genes tbx-9 and tbx-8 are required for formation of hypodermis and body-wall muscle in embryogenesis. Genes Cells (2004) 1.01
Distinct ribonucleoprotein reservoirs for microRNA and siRNA populations in C. elegans. RNA (2007) 0.86