Published in Mol Cancer on October 02, 2008
Barrett's oesophagus and oesophageal adenocarcinoma: time for a new synthesis. Nat Rev Cancer (2010) 3.27
Quantitation of DNA methylation by melt curve analysis. BMC Cancer (2009) 1.06
EZH2 dependent H3K27me3 is involved in epigenetic silencing of ID4 in prostate cancer. Oncotarget (2014) 0.94
DNA methylation profiling in Barrett's esophagus and esophageal adenocarcinoma reveals unique methylation signatures and molecular subclasses. Epigenetics (2011) 0.93
Role of epigenetic alterations in the pathogenesis of Barrett's esophagus and esophageal adenocarcinoma. Int J Clin Exp Pathol (2012) 0.92
Molecular mechanisms of Barrett's esophagus. Dig Dis Sci (2011) 0.89
Inhibitor of differentiation 4 (ID4): From development to cancer. Biochim Biophys Acta (2014) 0.89
Epigenetic and genetic silencing of CHFR in esophageal adenocarcinomas. Cancer (2010) 0.88
ID4 is frequently downregulated and partially hypermethylated in prostate cancer. World J Urol (2011) 0.84
Epigenetic inactivation of the SFRP1 gene in esophageal squamous cell carcinoma. Dig Dis Sci (2011) 0.84
Early events during neoplastic progression in Barrett's esophagus. Cancer Biomark (2010) 0.83
Genome-wide methylation analysis shows similar patterns in Barrett's esophagus and esophageal adenocarcinoma. Carcinogenesis (2013) 0.83
A Systematic Review of Esophageal MicroRNA Markers for Diagnosis and Monitoring of Barrett's Esophagus. Dig Dis Sci (2015) 0.82
Association of promoter methylation of RUNX3 gene with the development of esophageal cancer: a meta analysis. PLoS One (2014) 0.82
IGFBP7 is associated with poor prognosis in oesophageal adenocarcinoma and is regulated by promoter DNA methylation. Br J Cancer (2013) 0.80
Asymmetric strand segregation: epigenetic costs of genetic fidelity? PLoS Genet (2009) 0.78
Genetic and Epigenetic Alterations in Barrett's Esophagus and Esophageal Adenocarcinoma. Gastroenterol Clin North Am (2015) 0.78
Identification of the CIMP-like subtype and aberrant methylation of members of the chromosomal segregation and spindle assembly pathways in esophageal adenocarcinoma. Carcinogenesis (2016) 0.76
Integrated molecular analysis reveals complex interactions between genomic and epigenomic alterations in esophageal adenocarcinomas. Sci Rep (2017) 0.75
Hepatocyte paraffin 1 antigen as a biomarker for early diagnosis of Barrett esophagus. Am J Clin Pathol (2012) 0.75
Methylation-specific PCR: a novel PCR assay for methylation status of CpG islands. Proc Natl Acad Sci U S A (1996) 29.54
MethyLight: a high-throughput assay to measure DNA methylation. Nucleic Acids Res (2000) 9.30
Is there publication bias in the reporting of cancer risk in Barrett's esophagus? Gastroenterology (2000) 4.74
ID helix-loop-helix proteins in cell growth, differentiation and tumorigenesis. J Cell Sci (2000) 3.85
Epigenetic patterns in the progression of esophageal adenocarcinoma. Cancer Res (2001) 3.70
Evolution of neoplastic cell lineages in Barrett oesophagus. Nat Genet (1999) 3.30
NSAIDs modulate CDKN2A, TP53, and DNA content risk for progression to esophageal adenocarcinoma. PLoS Med (2007) 2.23
Inactivation of p16, RUNX3, and HPP1 occurs early in Barrett's-associated neoplastic progression and predicts progression risk. Oncogene (2005) 2.07
p16(INK4a) lesions are common, early abnormalities that undergo clonal expansion in Barrett's metaplastic epithelium. Cancer Res (2001) 2.06
Molecular and cellular features of esophageal cancer cells. J Cancer Res Clin Oncol (1993) 1.95
Aberrant methylation of secreted frizzled-related protein genes in esophageal adenocarcinoma and Barrett's esophagus. Int J Cancer (2005) 1.75
Risk of adenocarcinoma in Barrett's oesophagus: population based study. BMJ (2003) 1.61
Chromosomal imbalances in Barrett's adenocarcinoma and the metaplasia-dysplasia-carcinoma sequence. Am J Pathol (2000) 1.57
Focus on Barrett's esophagus and esophageal adenocarcinoma. Cancer Cell (2004) 1.57
Transcriptional profiling suggests that Barrett's metaplasia is an early intermediate stage in esophageal adenocarcinogenesis. Oncogene (2006) 1.55
TP53 gene mutations are rare in nondysplastic Barrett's esophagus. Dig Dis Sci (2006) 1.42
Genetic pathways involved in the progression of Barrett's metaplasia to adenocarcinoma. Br J Surg (2002) 1.40
Allelic loss of 9p21 and mutation of the CDKN2/p16 gene develop as early lesions during neoplastic progression in Barrett's esophagus. Oncogene (1996) 1.32
Mistaken identity of widely used esophageal adenocarcinoma cell line TE-7. Cancer Res (2007) 1.27
Epigenetic inactivation of ID4 in colorectal carcinomas correlates with poor differentiation and unfavorable prognosis. Clin Cancer Res (2004) 1.25
Aberrant hypermethylation of ID4 gene promoter region increases risk of lymph node metastasis in T1 breast cancer. Oncogene (2005) 1.24
Methylation of APC, TIMP3, and TERT: a new predictive marker to distinguish Barrett's oesophagus patients at risk for malignant transformation. J Pathol (2006) 1.12
Downregulation of ID4 by promoter hypermethylation in gastric adenocarcinoma. Oncogene (2003) 1.09
Metallothionien 3 expression is frequently down-regulated in oesophageal squamous cell carcinoma by DNA methylation. Mol Cancer (2005) 1.03
Id proteins in epithelial cells. Exp Cell Res (2003) 1.01
Chromosomal gains and genomic loss of p53 and p16 genes in Barrett's esophagus detected by fluorescence in situ hybridization of cytology specimens. Mod Pathol (2004) 1.00
p16 expression in Barrett's esophagus and esophageal adenocarcinoma: association with genetic and epigenetic alterations. Cancer Lett (2005) 1.00
LOH at the sites of the DCC, APC, and TP53 tumor suppressor genes occurs in Barrett's metaplasia and dysplasia adjacent to adenocarcinoma of the esophagus. Hum Pathol (1999) 0.98
A ligation assay for multiplex analysis of CpG methylation using bisulfite-treated DNA. Nucleic Acids Res (2007) 0.93
Frequent DNA methylation but not mutation of the ID4 gene in malignant lymphoma. J Clin Exp Hematop (2007) 0.92
Clinical use of p53 in Barrett's esophagus. Cancer Epidemiol Biomarkers Prev (2006) 0.89
Molecular findings in Barrett's epithelium. Dig Dis (2004) 0.88
Methylation of TIMP3 in esophageal squamous cell carcinoma. World J Gastroenterol (2008) 0.87
Multiple forms of genetic instability within a 2-Mb chromosomal segment of 3q26.3-q27 are associated with development of esophageal adenocarcinoma. Genes Chromosomes Cancer (2006) 0.81
Systematic review: the application of molecular pathogenesis to prevention and treatment of oesophageal adenocarcinoma. Aliment Pharmacol Ther (2007) 0.77
Final trial report of sentinel-node biopsy versus nodal observation in melanoma. N Engl J Med (2014) 10.69
High frequency of BRAF mutations in nevi. Nat Genet (2002) 9.95
A versatile gene-based test for genome-wide association studies. Am J Hum Genet (2010) 8.44
Meta-analysis identifies 29 additional ulcerative colitis risk loci, increasing the number of confirmed associations to 47. Nat Genet (2011) 7.98
Exome sequencing identifies recurrent somatic RAC1 mutations in melanoma. Nat Genet (2012) 7.00
Survival benefits from neoadjuvant chemoradiotherapy or chemotherapy in oesophageal carcinoma: a meta-analysis. Lancet Oncol (2007) 6.82
Menin associates with a trithorax family histone methyltransferase complex and with the hoxc8 locus. Mol Cell (2004) 6.08
Survival after neoadjuvant chemotherapy or chemoradiotherapy for resectable oesophageal carcinoma: an updated meta-analysis. Lancet Oncol (2011) 5.94
Surgery alone versus chemoradiotherapy followed by surgery for resectable cancer of the oesophagus: a randomised controlled phase III trial. Lancet Oncol (2005) 5.40
A genome-wide association study identifies novel alleles associated with hair color and skin pigmentation. PLoS Genet (2008) 4.57
Genome-wide association study identifies three loci associated with melanoma risk. Nat Genet (2009) 3.89
Common sequence variants on 20q11.22 confer melanoma susceptibility. Nat Genet (2008) 3.79
Transcriptional pathway signatures predict MEK addiction and response to selumetinib (AZD6244). Cancer Res (2010) 3.54
Adjuvant radiotherapy versus observation alone for patients at risk of lymph-node field relapse after therapeutic lymphadenectomy for melanoma: a randomised trial. Lancet Oncol (2012) 3.24
Progressive fibrosis in nonalcoholic steatohepatitis: association with altered regeneration and a ductular reaction. Gastroenterology (2007) 3.18
A single SNP in an evolutionary conserved region within intron 86 of the HERC2 gene determines human blue-brown eye color. Am J Hum Genet (2008) 3.00
A novel recurrent mutation in MITF predisposes to familial and sporadic melanoma. Nature (2011) 2.96
Melanocytic nevi, solar keratoses, and divergent pathways to cutaneous melanoma. J Natl Cancer Inst (2003) 2.70
Genome-wide association study identifies variants at 9p21 and 22q13 associated with development of cutaneous nevi. Nat Genet (2009) 2.65
International Consensus on Standardization of Data Collection for Complications Associated With Esophagectomy: Esophagectomy Complications Consensus Group (ECCG). Ann Surg (2015) 2.61
Comparison of the outcomes between open and minimally invasive esophagectomy. Ann Surg (2007) 2.60
CCAT2, a novel noncoding RNA mapping to 8q24, underlies metastatic progression and chromosomal instability in colon cancer. Genome Res (2013) 2.57
An autocrine TGF-beta/ZEB/miR-200 signaling network regulates establishment and maintenance of epithelial-mesenchymal transition. Mol Biol Cell (2011) 2.49
High-risk melanoma susceptibility genes and pancreatic cancer, neural system tumors, and uveal melanoma across GenoMEL. Cancer Res (2006) 2.40
Pathology features in Bethesda guidelines predict colorectal cancer microsatellite instability: a population-based study. Gastroenterology (2007) 2.39
Frequent somatic mutations in MAP3K5 and MAP3K9 in metastatic melanoma identified by exome sequencing. Nat Genet (2011) 2.36
Magnetic resonance imaging and spectroscopy accurately estimate the severity of steatosis provided the stage of fibrosis is considered. J Hepatol (2009) 2.30
Genome-wide association study identifies three new melanoma susceptibility loci. Nat Genet (2011) 2.29
Genome-wide association study identifies novel loci predisposing to cutaneous melanoma. Hum Mol Genet (2011) 2.26
Accuracy of PET-CT in predicting survival in patients with esophageal cancer. World J Surg (2012) 2.26
Assessment of higher order cognitive skills in undergraduate education: modified essay or multiple choice questions? Research paper. BMC Med Educ (2007) 2.23
Radiofrequency ablation of liver tumors: a systematic review. Arch Surg (2006) 2.22
Features associated with germline CDKN2A mutations: a GenoMEL study of melanoma-prone families from three continents. J Med Genet (2006) 2.17
A three-single-nucleotide polymorphism haplotype in intron 1 of OCA2 explains most human eye-color variation. Am J Hum Genet (2006) 2.14
Characterization of the Melanoma miRNAome by Deep Sequencing. PLoS One (2010) 2.08
Rare, evolutionarily unlikely missense substitutions in ATM confer increased risk of breast cancer. Am J Hum Genet (2009) 2.02
Nuclear PTEN expression and clinicopathologic features in a population-based series of primary cutaneous melanoma. Int J Cancer (2002) 2.02
Diagnosing skin cancer in primary care: how do mainstream general practitioners compare with primary care skin cancer clinic doctors? Med J Aust (2007) 1.99
Current Australian practice in the diagnosis and management of Barrett's oesophagus. ANZ J Surg (2013) 1.98
Metastasectomy for distant metastatic melanoma: analysis of data from the first Multicenter Selective Lymphadenectomy Trial (MSLT-I). Ann Surg Oncol (2012) 1.92
Tagging single nucleotide polymorphisms in cell cycle control genes and susceptibility to invasive epithelial ovarian cancer. Cancer Res (2007) 1.92
Association of Helicobacter pylori infection with reduced risk for esophageal cancer is independent of environmental and genetic modifiers. Gastroenterology (2010) 1.91
High-risk human papillomavirus in esophageal squamous cell carcinoma. Cancer Epidemiol Biomarkers Prev (2010) 1.83
Microarray expression profiling in melanoma reveals a BRAF mutation signature. Oncogene (2004) 1.83
Multiple pigmentation gene polymorphisms account for a substantial proportion of risk of cutaneous malignant melanoma. J Invest Dermatol (2009) 1.81
Gene expression signature predicts recurrence in lung adenocarcinoma. Clin Cancer Res (2007) 1.80
Steatosis: co-factor in other liver diseases. Hepatology (2005) 1.76
Interactive effects of MC1R and OCA2 on melanoma risk phenotypes. Hum Mol Genet (2004) 1.75
The Queensland Study of Melanoma: environmental and genetic associations (Q-MEGA); study design, baseline characteristics, and repeatability of phenotype and sun exposure measures. Twin Res Hum Genet (2008) 1.71
Ductular reactions in human liver: diversity at the interface. Hepatology (2011) 1.70
High rate of detection of primary aldosteronism, including surgically treatable forms, after 'non-selective' screening of hypertensive patients. J Hypertens (2003) 1.70
A genome-wide scan for naevus count: linkage to CDKN2A and to other chromosome regions. Eur J Hum Genet (2006) 1.70
Obesity and the risk of epithelial ovarian cancer: a systematic review and meta-analysis. Eur J Cancer (2007) 1.68
A genome-wide association study identifies new susceptibility loci for esophageal adenocarcinoma and Barrett's esophagus. Nat Genet (2013) 1.67
Laparoscopic repair of very large hiatus hernia with sutures versus absorbable mesh versus nonabsorbable mesh: a randomized controlled trial. Ann Surg (2015) 1.64
Temporal changes in the endoscopic frequency of new cases of Barrett's esophagus in an Australian health region. Am J Gastroenterol (2006) 1.63
Cigarette smoking and adenocarcinomas of the esophagus and esophagogastric junction: a pooled analysis from the international BEACON consortium. J Natl Cancer Inst (2010) 1.60
IFNgamma differentially controls the development of idiopathic pneumonia syndrome and GVHD of the gastrointestinal tract. Blood (2007) 1.59
Magnetic resonance imaging and spectroscopy for monitoring liver steatosis. J Magn Reson Imaging (2008) 1.56
Prospective randomized controlled trial of argon plasma coagulation ablation vs. endoscopic surveillance of patients with Barrett's esophagus after antireflux surgery. Gastrointest Endosc (2004) 1.56
IRF4 variants have age-specific effects on nevus count and predispose to melanoma. Am J Hum Genet (2010) 1.55
Type I-IFNs control GVHD and GVL responses after transplantation. Blood (2011) 1.54
Is concurrent radiation therapy required in patients receiving preoperative chemotherapy for adenocarcinoma of the oesophagus? A randomised phase II trial. Eur J Cancer (2011) 1.54
Cytokine expanded myeloid precursors function as regulatory antigen-presenting cells and promote tolerance through IL-10-producing regulatory T cells. J Immunol (2005) 1.53
Common variants at the MHC locus and at chromosome 16q24.1 predispose to Barrett's esophagus. Nat Genet (2012) 1.52
Soluble lymphotoxin is an important effector molecule in GVHD and GVL. Blood (2009) 1.50
Genome-wide copy number analysis in esophageal adenocarcinoma using high-density single-nucleotide polymorphism arrays. Cancer Res (2008) 1.50
Interactions among smoking, obesity, and symptoms of acid reflux in Barrett's esophagus. Cancer Epidemiol Biomarkers Prev (2005) 1.49
NRAS and BRAF mutations in cutaneous melanoma and the association with MC1R genotype: findings from Spanish and Austrian populations. J Invest Dermatol (2012) 1.49
Expression of HOXB2, a retinoic acid signaling target in pancreatic cancer and pancreatic intraepithelial neoplasia. Clin Cancer Res (2005) 1.48
Five-year follow-up of a multicenter, double-blind randomized clinical trial of laparoscopic Nissen vs anterior 90 degrees partial fundoplication. Arch Surg (2010) 1.48
Obesity and risk of ovarian cancer subtypes: evidence from the Ovarian Cancer Association Consortium. Endocr Relat Cancer (2013) 1.47
Serum hyaluronic acid with serum ferritin accurately predicts cirrhosis and reduces the need for liver biopsy in C282Y hemochromatosis. Hepatology (2009) 1.47
A genome scan for eye color in 502 twin families: most variation is due to a QTL on chromosome 15q. Twin Res (2004) 1.47
SiDCoN: a tool to aid scoring of DNA copy number changes in SNP chip data. PLoS One (2007) 1.46