Studies on the toxicology of podophyllotoxin and related substances.

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Published in Fed Proc on March 01, 1948

Authors

F S PHILIPS, M B CHENOWETH, C C HUNT

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The effect of stretch receptors from muscle on the discharge of motorneurons. J Physiol (1952) 4.33

Monosynaptic reflex response of spinal motoneurons to graded afferent stimulation. J Gen Physiol (1955) 3.72

An analysis of fibre diameter and receptor characteristics of myelinated cutaneous afferent fibres in cat. J Physiol (1960) 3.41

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The mammalian small-nerve fibers: a system for efferent nervous regulation of muscle spindle discharge. Res Publ Assoc Res Nerv Ment Dis (1952) 3.02

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Transmission in fractionated monosynaptic spinal reflex systems. J Gen Physiol (1955) 2.54

Motor innervation of skeletal muscle: multiple innervation of individual muscle fibres and motor unit function. J Physiol (1954) 2.48

Temporal fluctuation in excitability of spinal motoneurons and its influence on monosynaptic reflex response. J Gen Physiol (1955) 2.28

Cyclophosphamide and urinary bladder toxicity. Cancer Res (1961) 2.20

Properties of cutaneous touch receptors in cat. J Physiol (1960) 2.11

Properties of spinal interneurones. J Physiol (1959) 1.91

Recent contributions to the pharmacology of bis(2-haloethyl) amines and sulfides. J Pharmacol Exp Ther (1950) 1.77

Analysis of reflex variability in terms of partially correlated excitability fluctuation in a population of motoneurons. J Gen Physiol (1956) 1.75

Chromosome alteration and tumour inhibition by nitrogen mustards; the hypothesis of crosslinking alkylation. Nature (1950) 1.74

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Background discharge and evoked responses of spinal interneurones. J Physiol (1959) 1.51

Enzymatic deamination and vasodepressor effects of adenosine analogs. J Pharmacol Exp Ther (1952) 1.50

Spinal reflex mechanisms concerned with skeletal muscle. Physiol Rev (1960) 1.47

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Intrathecal amethopterin in neurological manifestations of leukemia. AMA Arch Intern Med (1958) 1.36

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A stationary manometric respirometer for isolated rat diaphragm allowing simultaneous direct registration of mechanical activity; observations with sodium azide and dinitrophenol. J Pharmacol Exp Ther (1952) 1.32

Pharmacological and pathological effects of alkylating agents. Ann N Y Acad Sci (1958) 1.30

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Responses of the nerve terminal of the Pacinian corpuscle. J Physiol (1962) 1.27

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The toxicity of actinomycin D. Ann N Y Acad Sci (1960) 1.24

The toxic effects of 6-mercaptopurine and related compounds. Ann N Y Acad Sci (1954) 1.18

Effect of 4-amino-pteroylglutamic acid (aminopterin) on early pregnancy. Proc Soc Exp Biol Med (1950) 1.17

Effect of adenosine analogs on isolated intestine and uterus. J Pharmacol Exp Ther (1954) 1.14

Adenine intoxication in relation to in vivo formation and deposition of 2,8-dioxyadenine in renal tubules. J Pharmacol Exp Ther (1952) 1.11

Effects of N-methylformamide and related compounds in mouse sarcoma 180. Proc Soc Exp Biol Med (1953) 1.08

Chelation as a mechanism of pharmacological action. Pharmacol Rev (1956) 1.06

Muscle stretch receptors; peripheral mechanisms and reflex function. Cold Spring Harb Symp Quant Biol (1952) 1.03

MITOMYCIN C: CHEMICAL AND BIOLOGICAL STUDIES ON ALKYLATION. Science (1963) 1.03

Metabolic disturbances produced by some fluoro-fatty acids; relation to the pharmacologic activity of these compounds. J Pharmacol Exp Ther (1952) 1.00

Pharmacology of mitomycin C. I. Toxicity and pathologic effects. Cancer Res (1960) 0.98

THE METABOLISM OF VOLATILE ANESTHETICS. II. IN VITRO METABOLISM OF METHOXYFLURANE AND HALOTHANE IN RAT LIVER SLICES AND CELL FRACTIONS. Biochem Pharmacol (1965) 0.98

HISTOCHEMICAL DEMONSTRATION OF ZINC IN THE DORSOLATERAL PROSTATE OF THE RAT: STUDIES WITH OXINE AND DITHIZONE. Am J Pathol (1965) 0.97

The nitrogen mustard-like actions of 2,4,6-tris (ethylenimino)-s-triazine and other bis(ethylenimines). J Pharmacol Exp Ther (1950) 0.93

Relations between zinc content and the selective cytotoxicity of diphenylthiocarbazone. Fed Proc (1961) 0.92

PHARMACOLOGY OF MITOMYCIN C. IV. EFFECTS IN VIVO ON NUCLEIC ACID SYNTHESIS; COMPARISON WITH ACTINOMYCIN D. Cancer Res (1963) 0.90

Factors influencing fluoroacetate poisoning; practical treatment with glycerol monoacetate. J Pharmacol Exp Ther (1951) 0.89

Monofluoroacetic acid and related compounds. Pharmacol Rev (1949) 0.88

Biological effects of 6-aminonicotinamide. Bull N Y Acad Med (1959) 0.88

Blood and tissue levels of ether, chloroform, halothane and methoxyflurane in dogs. Anesthesiology (1962) 0.87

Antagonism of three homologous mono-fluorinated fatty acids by several fatty acids. J Pharmacol Exp Ther (1954) 0.87

Effects of 6-mercaptopurine and analogs on experimental tumors. Ann N Y Acad Sci (1954) 0.87

Assays with first- or second-generation transplants of spontaneous mammary adenocarcinomas of mice. Cancer Res (1955) 0.87

The biological actions and therapeutic applications of the B-chloroethyl amines and sulfides. Science (1946) 0.86

The renal clearance of thiosulfate in man. Bull Johns Hopkins Hosp (1946) 0.86

Fluoroacetate and fluorobutyrate convulsions in the isolated cerebral cortex of the dog. J Pharmacol Exp Ther (1955) 0.86

The renal clearance of thiosulfate with observations on its volume distribution. Am J Physiol (1946) 0.85

Effects of thioguanine in mammals. Cancer (1957) 0.85

The action of 4-amino-N10-methyl-pteroylglutamic acid in mice, rats, and dogs. J Pharmacol Exp Ther (1950) 0.85

METABOLISM OF VOLATILE ANASTHETICS. I. CONVERSION IN VIVO OF SEVERAL ANESTHETICS TO 14CO-2 AND CHLORIDE. Biochem Pharmacol (1964) 0.84

Tissue copper determinations in a case of hepatolenticular degeneration treated with BAL (dimercaprol). Med Bull (Ann Arbor) (1953) 0.82

Production of fatty livers by 4-aminopyrazolo-(3, 4-d)-pyrimidine; toxicological and pathological studies. Proc Soc Exp Biol Med (1956) 0.81

Effects of 4-amino-pteroylglutamic acid in dogs with special reference to megaloblastosis. Proc Soc Exp Biol Med (1949) 0.80

The T deflection of isolated mammalian heart muscle electrogram. Circ Res (1953) 0.80

Studies of the action of 4-aminopteroylglutamic acid and its congeners in mammals. Ann N Y Acad Sci (1950) 0.79

Pharmacology of mitomycin C. II. Renal excretion and metabolism by tissue hemogenates. J Pharmacol Exp Ther (1961) 0.78

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Electrogram of isolated papillary muscle of the cat heart. Am J Physiol (1949) 0.75

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Therapeutic uses of BAL. N Y State J Med (1948) 0.75

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Pharmacology of fluoroacetate. Fed Proc (1946) 0.75

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Reversal of the pressor response to carotid clamping by fluoroacetate-fluoride mixtures. J Pharmacol Exp Ther (1953) 0.75

Studies on ventricular fibrillation produced by epinephrine during hydrocarbon inhalation. Fed Proc (1948) 0.75

Toxicological and pathological studies with 3,3-dimethyl-1-phenyltriazene: with special reference to hepatic damage. Proc Soc Exp Biol Med (1957) 0.75

Ventricular fibrillation induced by hydrocarbons and epinephrine. J Ind Hyg Toxicol (1946) 0.75

Energy metabolism of rabbit intestine as influenced by metabolic blocking agents. J Pharmacol Exp Ther (1950) 0.75

Tolerance to fluoroacetate and fluorobutyrate in rats. J Pharmacol Exp Ther (1952) 0.75

Toxicity of 2,3-dimercaptopropanol (BAL). J Pharmacol Exp Ther (1946) 0.75