Published in Angew Chem Int Ed Engl on January 01, 2009
Binary fluorous tagging enables the synthesis and separation of a 16-stereoisomer library of macrosphelides. Nat Chem (2012) 0.89
One-pot two-step radiosynthesis of a new (18)F-labeled thiol reactive prosthetic group and its conjugate for insulinoma imaging. Mol Pharm (2014) 0.85
Fluorine-18 Radiolabeled PET Tracers for Imaging Monoamine Transporters: Dopamine, Serotonin, and Norepinephrine. PET Clin (2009) 0.82
Triazole Appending Agent (TAAG): A New Synthon for Preparing Iodine-Based Molecular Imaging and Radiotherapy Agents. ACS Med Chem Lett (2012) 0.79
18F-glutathione conjugate as a PET tracer for imaging tumors that overexpress L-PGDS enzyme. PLoS One (2014) 0.77
Fluorine-18 patents (2009-2015). Part 2: new radiochemistry. Pharm Pat Anal (2016) 0.75
Journal club. An organic chemist highlights an ingenious way to make radiotracers. Nature (2009) 0.75
18F-labelled intermediates for radiosynthesis by modular build-up reactions: newer developments. Biomed Res Int (2014) 0.75
Fluorine in medicinal chemistry. Chem Soc Rev (2007) 6.99
A comparison of the behavior of (64)Cu-acetate and (64)Cu-ATSM in vitro and in vivo. J Nucl Med (2013) 1.55
Radiosynthesis and evaluation of [18F]Selectfluor bis(triflate). Angew Chem Int Ed Engl (2010) 1.48
18F labeling of arenes. Angew Chem Int Ed Engl (2012) 1.39
Palladium-catalyzed allylic fluorination. Angew Chem Int Ed Engl (2011) 1.24
Transition metal catalysis and nucleophilic fluorination. Chem Commun (Camb) (2012) 1.16
A general copper-mediated nucleophilic 18F fluorination of arenes. Angew Chem Int Ed Engl (2014) 1.14
Metal-free oxidative fluorination of phenols with [18F]fluoride. Angew Chem Int Ed Engl (2012) 1.10
Using chemical genetics and ATP analogues to dissect protein kinase function. ACS Chem Biol (2007) 1.06
Catalytic asymmetric fluorinations. Org Biomol Chem (2006) 1.06
Synthesis and reactivity of [18F]-N-fluorobenzenesulfonimide. Chem Commun (Camb) (2007) 1.05
Multi-stage learning for robust lung segmentation in challenging CT volumes. Med Image Comput Comput Assist Interv (2011) 1.05
A broadly applicable [18F]trifluoromethylation of aryl and heteroaryl iodides for PET imaging. Nat Chem (2013) 1.03
Organocatalyzed enantioselective fluorocyclizations. Angew Chem Int Ed Engl (2011) 1.03
Diels-Alder exo selectivity in terminal-substituted dienes and dienophiles: experimental discoveries and computational explanations. J Am Chem Soc (2009) 0.99
Synthesis and reactivity of novel gamma-phosphate modified ATP analogues. Bioorg Med Chem Lett (2009) 0.97
Gold-catalyzed intramolecular oxidative cross-coupling of nonactivated arenes. Chemistry (2010) 0.96
Use of the Resection Map system as guidance during hepatectomy. Surg Endosc (2010) 0.95
Enantioselective organocatalytic aldol reaction of ynones and its synthetic applications. Org Lett (2006) 0.95
Au(I) /Au(III) catalysis: an alternative approach for C-C oxidative coupling. Chemistry (2011) 0.95
The chemistry of propargylic and allylic fluorides. Chem Rev (2008) 0.93
Catalytic decarboxylative fluorination for the synthesis of tri- and difluoromethyl arenes. Org Lett (2013) 0.93
A quantitative comparison of wild-type and gatekeeper mutant cdk2 for chemical genetic studies with ATP analogues. Chembiochem (2009) 0.92
Trifluoromethylation of allylsilanes under photoredox catalysis. Org Lett (2013) 0.91
Diastereoselective ring-closing metathesis: synthesis of P-stereogenic phosphinates from prochiral phosphinic acid derivatives. J Org Chem (2005) 0.90
Enhanced aqueous Suzuki-Miyaura coupling allows site-specific polypeptide 18F-labeling. J Am Chem Soc (2013) 0.90
Evaluation of deuterated 18F- and 11C-labeled choline analogs for cancer detection by positron emission tomography. Clin Cancer Res (2012) 0.90
Catalytic hydrotrifluoromethylation of unactivated alkenes. J Am Chem Soc (2013) 0.90
The traceless Staudinger ligation for indirect 18F-radiolabelling. Org Biomol Chem (2010) 0.87
Automatic multi-organ segmentation using learning-based segmentation and level set optimization. Med Image Comput Comput Assist Interv (2011) 0.86
A catalytic asymmetric bioorganic route to enantioenriched tetrahydro- and dihydropyranones. J Am Chem Soc (2005) 0.86
Trifluoromethylation of allylsilanes under copper catalysis. Chemistry (2012) 0.85
[18F]fluorination of an arylboronic ester using [18F]selectfluor bis(triflate): application to 6-[18F]fluoro-L-DOPA. Chem Commun (Camb) (2013) 0.85
Enantioselective synthesis of P-stereogenic phosphinates and phosphine oxides by molybdenum-catalyzed asymmetric ring-closing metathesis. Angew Chem Int Ed Engl (2009) 0.84
Pd(II)-catalyzed cascade Wacker-Heck reaction: chemoselective coupling of two electron-deficient reactants. J Org Chem (2006) 0.84
Intramolecular OH···FC hydrogen bonding in fluorinated carbohydrates: CHF is a better hydrogen bond acceptor than CF2. Angew Chem Int Ed Engl (2013) 0.84
Synthesis of novel enantiopure fluorinated building blocks from acyclic chiral allylsilanes. Org Lett (2005) 0.83
Synthesis and evaluation of nucleoside radiotracers for imaging proliferation. Nucl Med Biol (2012) 0.83
Automated 3-D echocardiography analysis compared with manual delineations and SPECT MUGA. IEEE Trans Med Imaging (2002) 0.83
A novel radiotracer to image glycogen metabolism in tumors by positron emission tomography. Cancer Res (2014) 0.83
Asymmetric fluorocyclizations of alkenes. Acc Chem Res (2014) 0.83
Transition-metal-mediated reactions for C(sp2)-F bond construction: the state of play. Angew Chem Int Ed Engl (2009) 0.83
Copper-free click--a promising tool for pre-targeted PET imaging. Chem Commun (Camb) (2011) 0.83
Electrophilic fluorocyclization of allyl silanes. Angew Chem Int Ed Engl (2009) 0.83
Palladium-catalyzed substitution and cross-coupling of benzylic fluorides. Org Lett (2012) 0.83
Biodistribution and radiation dosimetry of deuterium-substituted 18F-fluoromethyl-[1, 2-2H4]choline in healthy volunteers. J Nucl Med (2014) 0.83
Regio- and enantioselective synthesis of allylic fluorides by electrophilic fluorodesilylation of allyl silanes. Angew Chem Int Ed Engl (2003) 0.82
Gold(I)-catalyzed alkoxyhalogenation of beta-hydroxy-alpha,alpha-difluoroynones. Angew Chem Int Ed Engl (2008) 0.82
Fluorine-directed diastereoselective iodocyclizations. Angew Chem Int Ed Engl (2008) 0.81
A concise synthesis of enantioenriched fluorinated carbocycles. Angew Chem Int Ed Engl (2007) 0.81
Synthesis of highly substituted pyridazines through alkynyl boronic ester cycloaddition reactions. Angew Chem Int Ed Engl (2005) 0.81
A dual radiolabelling approach for tracking metal complexes: investigating the speciation of copper bis(thiosemicarbazonates) in vitro and in vivo. Metallomics (2015) 0.81
Palladium-catalyzed oxidative cyclizations: synthesis of dihydropyranones and furanones. J Org Chem (2005) 0.81
Palladium-catalyzed substitution of allylic fluorides. Angew Chem Int Ed Engl (2009) 0.80
Asymmetric electrophilic fluorocyclization with carbon nucleophiles. Angew Chem Int Ed Engl (2013) 0.80
Pre-clinical evaluation of a 3-nitro-1,2,4-triazole analogue of [18F]FMISO as hypoxia-selective tracer for PET. Nucl Med Biol (2010) 0.80
Stereoselective synthesis of internal allylic fluorides. Org Biomol Chem (2004) 0.80
Sequential desymmetrization-fluorination: enantioselective synthesis of fluorinated cyclitols. Chemistry (2006) 0.80
New frontiers in the design and synthesis of imaging probes for PET oncology: current challenges and future directions. Mol Imaging Biol (2012) 0.79
Bis(thiosemicarbazones) as bifunctional chelators for the room temperature 64-copper labeling of peptides. Dalton Trans (2010) 0.79
Enantioselective synthesis of a key "A-ring" intermediate for the preparation of 1alpha-fluoro vitamin D3 analogues. J Org Chem (2006) 0.79
Bioorthogonal chemistry for (68) Ga radiolabelling of DOTA-containing compounds. J Labelled Comp Radiopharm (2013) 0.78
Sequential cross-metathesis/electrophilic fluorodesilylation: a novel entry to functionalized allylic fluorides. Org Lett (2003) 0.78
cis-Specific hydrofluorination of alkenylarenes under palladium catalysis through an ionic pathway. Angew Chem Int Ed Engl (2014) 0.78
Diastereoselective synthesis of P-stereogenic heterocycles via enyne ring-closing metathesis. Org Lett (2010) 0.78
Objective quantification of global and regional left ventricular systolic function by endocardial tracking of contrast echocardiographic sequences. Int J Cardiol (2007) 0.78
Radiolabeled RGD tracer kinetics annotates differential αvβ 3 integrin expression linked to cell intrinsic and vessel expression. Mol Imaging Biol (2013) 0.78
Diversity-oriented approach to CF3CHF-, CF3CFBr-, CF3CF2-, (CF3)2CH-, and CF3(SCF3)CH-substituted arenes from 1-(diazo-2,2,2-trifluoroethyl)arenes. Org Lett (2014) 0.78
Intramolecular hetero-Michael addition of beta-hydroxyenones for the preparation of highly substituted tetrahydropyranones. Chemistry (2006) 0.78
The chemoselective one-step alkylation and isolation of thiophosphorylated cdk2 substrates in the presence of native cysteine. Chembiochem (2011) 0.78
Gold-catalyzed cascade cyclization-oxidative alkynylation of allenoates. Org Lett (2010) 0.78
Electrophilic fluorodesilylation of allenylmethylsilanes: a novel entry to 2-fluoro-1,3-dienes. Org Lett (2005) 0.77
Radiochemistry: Flipping fluoride's reactivity. Nat Chem (2012) 0.77
Catalytic enantioselective synthesis of P-stereogenic compounds. Chem Commun (Camb) (2010) 0.77
Electrophilic fluorination of organosilanes. Org Biomol Chem (2005) 0.77
A two-directional approach to enantiopure 1,4-difluoro-cyclohexenes: synthesis of difluorinated cyclitol analogues. Org Lett (2008) 0.77
A fluorous and click approach for screening potential PET probes: Evaluation of potential hypoxia biomarkers. Bioorg Med Chem (2011) 0.77
Developments in fluorocyclization methodologies. Future Med Chem (2009) 0.76
An alkynylboronic ester cycloaddition route to functionalised aromatic boronic esters. Chem Commun (Camb) (2006) 0.76
Conformational analysis of fluorinated pyrrolidines using 19F-1H scalar couplings and heteronuclear NOEs. Chemistry (2012) 0.76
Identification, optimization, and pharmacology of acylurea GHS-R1a inverse agonists. J Med Chem (2014) 0.75
Single and double stereoselective fluorination of (E)-allylsilanes. Beilstein J Org Chem (2007) 0.75
Oxidative cyclization of beta-hydroxyenones with palladium(II): a novel entry to 2,3-dihydro-4H-pyran-4-ones. Org Lett (2004) 0.75
Synthesis and O-phosphorylation of 3,3,4,4-tetrafluoroaryl-C-nucleoside analogues. Org Biomol Chem (2010) 0.75
Synthesis and characterization of a novel N-F reagent derived from the ethano-Tröger's base: (1)JFN coupling constants as a signature for the N-F bond. Chem Commun (Camb) (2015) 0.75
Stereospecific anti SE2' fluorination of allenylsilanes: synthesis of enantioenriched propargylic fluorides. Org Biomol Chem (2008) 0.75
Synthesis of 3-fluoropyrrolidines and 4-fluoropyrrolidin-2-ones from allylic fluorides. Chemistry (2012) 0.75
Fluorous synthesis of allylic fluorides: C-F bond formation as the detagging process. Chem Commun (Camb) (2008) 0.75
Orthogonal 18F and 64Cu labelling of functionalised bis(thiosemicarbazonato) complexes. Chem Commun (Camb) (2010) 0.75
Exploring the roles of protein kinases using chemical genetics. Future Med Chem (2009) 0.75
Synthesis of propargylic fluorides from allenylsilanes. Chem Commun (Camb) (2006) 0.75
Unprecedented regiocontrol using an aldolase I antibody. Angew Chem Int Ed Engl (2002) 0.75
PET Imaging of Steroid Hormone Receptor Expression. Mol Imaging (2015) 0.75