Published in J Gen Virol on January 01, 2009
Identification of an effective siRNA target site and functional regulatory elements, within the hepatitis B virus posttranscriptional regulatory element. Virol J (2010) 0.85
Gene therapeutic approaches to inhibit hepatitis B virus replication. World J Hepatol (2015) 0.82
Baculovirus-mediated gene delivery and RNAi applications. Viruses (2015) 0.79
Progress in the use of RNA interference as a therapy for chronic hepatitis B virus infection. Genome Med (2010) 0.79
Inhibition of hepatitis B virus replication in vivo using lipoplexes containing altritol-modified antiviral siRNAs. Artif DNA PNA XNA (2010) 0.78
trans-Complementation of HBV rtM204I mutant replication by HBV wild-type polymerase. Virology (2009) 0.75
Changes in innate and permissive immune responses after hbv transgenic mouse vaccination and long-term-siRNA treatment [corrected]. PLoS One (2013) 0.75
Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction. Anal Biochem (1987) 281.19
Potent and specific genetic interference by double-stranded RNA in Caenorhabditis elegans. Nature (1998) 72.56
An abundant class of tiny RNAs with probable regulatory roles in Caenorhabditis elegans. Science (2001) 44.16
An RNA-directed nuclease mediates post-transcriptional gene silencing in Drosophila cells. Nature (2000) 23.17
Argonaute2, a link between genetic and biochemical analyses of RNAi. Science (2001) 15.32
Human hepatocellular carcinoma cell lines secrete the major plasma proteins and hepatitis B surface antigen. Science (1980) 13.44
The molecular biology of the hepatitis B viruses. Annu Rev Biochem (1987) 12.32
Hepatitis B virus infection--natural history and clinical consequences. N Engl J Med (2004) 10.91
Hepatitis B virus. The major etiology of hepatocellular carcinoma. Cancer (1988) 7.05
Baculovirus as versatile vectors for protein expression in insect and mammalian cells. Nat Biotechnol (2005) 3.37
Orthotopic liver transplantation for patients with hepatitis B virus-related liver disease. Hepatology (1991) 3.34
Inhibition of hepatitis B virus in mice by RNA interference. Nat Biotechnol (2003) 3.15
Efficient gene transfer into human hepatocytes by baculovirus vectors. Proc Natl Acad Sci U S A (1995) 2.60
Baculovirus-mediated gene transfer into mammalian cells. Proc Natl Acad Sci U S A (1996) 2.50
Global programme for control of hepatitis B infection. Vaccine (1995) 2.17
Hepatitis B virus mutants associated with 3TC and famciclovir administration are replication defective. Hepatology (1998) 2.01
RNA interference-mediated control of hepatitis B virus and emergence of resistant mutant. Gastroenterology (2005) 1.85
Low dynamic state of viral competition in a chronic avian hepadnavirus infection. J Virol (2000) 1.66
Inhibition of hepatitis B virus expression and replication by RNA interference. Hepatology (2003) 1.59
Baculovirus induces an innate immune response and confers protection from lethal influenza virus infection in mice. J Immunol (2003) 1.57
Recombinant baculoviruses as mammalian cell gene-delivery vectors. Trends Biotechnol (2002) 1.55
Combination therapy with lamivudine and famciclovir for chronic hepatitis B-infected Chinese patients: a viral dynamics study. Hepatology (2000) 1.50
Prophylaxis against hepatitis B recurrence following liver transplantation using combination lamivudine and hepatitis B immune globulin. Hepatology (1998) 1.48
Hepatitis B virus reinfection after orthotopic liver transplantation. Serological and clinical implications. J Hepatol (1992) 1.46
Hepatitis B virus replication in human HepG2 cells mediated by hepatitis B virus recombinant baculovirus. Hepatology (1998) 1.41
Clearance of hepatitis B virus from the liver of transgenic mice by short hairpin RNAs. Proc Natl Acad Sci U S A (2005) 1.30
Prevention of hepatitis B recurrence after liver transplantation using lamivudine or lamivudine combined with hepatitis B Immunoglobulin prophylaxis. Liver Transpl (2006) 1.29
Baculovirus-based vaccination vectors allow for efficient induction of immune responses against plasmodium falciparum circumsporozoite protein. Mol Ther (2007) 1.18
Nucleoside analogues for chronic hepatitis B: antiviral efficacy and viral resistance. Am J Gastroenterol (2002) 1.12
Use of the hepatitis B virus recombinant baculovirus-HepG2 system to study the effects of (-)-beta-2',3'-dideoxy-3'-thiacytidine on replication of hepatitis B virus and accumulation of covalently closed circular DNA. Antimicrob Agents Chemother (1999) 1.05
An efficacy and cost-effectiveness analysis of combination hepatitis B immune globulin and lamivudine to prevent recurrent hepatitis B after orthotopic liver transplantation compared with hepatitis B immune globulin monotherapy. Liver Transpl (2000) 1.05
Recombinant baculovirus containing the diphtheria toxin A gene for malignant glioma therapy. Cancer Res (2006) 1.03
Long-term inhibition of hepatitis B virus in transgenic mice by double-stranded adeno-associated virus 8-delivered short hairpin RNA. Gene Ther (2006) 1.00
Stable inhibition of hepatitis B virus proteins by small interfering RNA expressed from viral vectors. J Gene Med (2005) 0.98
siRNA-mediated inhibition of HBV replication and expression. World J Gastroenterol (2004) 0.93
RNA interference mediated in human primary cells via recombinant baculoviral vectors. Mol Ther (2005) 0.89
Rebound of hepatitis B virus replication in HepG2 cells after cessation of antiviral treatment. J Virol (2002) 0.88
Hepatitis B virus infection. Bull World Health Organ (1998) 0.85
Inhibition of Hepatitis B virus cccDNA replication by siRNA. Biochem Biophys Res Commun (2007) 0.85
Direct vaccination with pseudotype baculovirus expressing murine telomerase induces anti-tumor immunity comparable with RNA-electroporated dendritic cells in a murine glioma model. Cancer Lett (2006) 0.84
Comparison of anti-hepatitis B virus activities of lamivudine and clevudine by a quantitative assay. Antimicrob Agents Chemother (2003) 0.83
Use of baculovirus expression vectors. Methods Mol Biol (1997) 0.81
A retrovirus-based system to stably silence hepatitis B virus genes by RNA interference. Biotechnol Lett (2006) 0.81
Therapeutic inhibition of hepatitis B virus surface antigen expression by RNA interference. Biochem Biophys Res Commun (2005) 0.81
Combination of small interfering RNAs mediates greater suppression on hepatitis B virus cccDNA in HepG2.2.15 cells. World J Gastroenterol (2008) 0.78
In vitro study of the effects of precore and lamivudine-resistant mutations on hepatitis B virus replication. J Virol (2007) 0.78
Ligand activation of peroxisome proliferator-activated receptor beta/delta (PPARbeta/delta) attenuates carbon tetrachloride hepatotoxicity by downregulating proinflammatory gene expression. Toxicol Sci (2008) 1.07
Nanoliposomal ceramide prevents in vivo growth of hepatocellular carcinoma. Gut (2010) 1.02
Regression of established hepatocellular carcinoma is induced by chemoimmunotherapy in an orthotopic murine model. Hepatology (2012) 0.93
Tumor necrosis factor-alpha acts as a complete mitogen for primary rat hepatocytes. Am J Pathol (2003) 0.89
Rebound of hepatitis B virus replication in HepG2 cells after cessation of antiviral treatment. J Virol (2002) 0.88
Gap junction-mediated intercellular communication in a long-term primary mouse hepatocyte culture system. Hepatology (2003) 0.87
Comparison of anti-hepatitis B virus activities of lamivudine and clevudine by a quantitative assay. Antimicrob Agents Chemother (2003) 0.83
Elevated hepatic iron activates NF-E2-related factor 2-regulated pathway in a dietary iron overload mouse model. Toxicol Sci (2012) 0.82
The lipophilic iron compound TMH-ferrocene [(3,5,5-trimethylhexanoyl)ferrocene] increases iron concentrations, neuronal L-ferritin, and heme oxygenase in brains of BALB/c mice. Biol Trace Elem Res (2002) 0.81
Iron potentiates acetaminophen-induced oxidative stress and mitochondrial dysfunction in cultured mouse hepatocytes. Toxicol Sci (2010) 0.79
Expression of E-cadherin and other paracellular junction genes is decreased in iron-loaded hepatocytes. Am J Pathol (2003) 0.79
In vitro study of the effects of precore and lamivudine-resistant mutations on hepatitis B virus replication. J Virol (2007) 0.78
Myocyte Dedifferentiation Drives Extraocular Muscle Regeneration in Adult Zebrafish. Invest Ophthalmol Vis Sci (2015) 0.78
3,5,5-trimethyl-hexanoyl-ferrocene diet protects mice from moderate transient acetaminophen-induced hepatotoxicity. Toxicol Sci (2011) 0.77
Effects of modulators of protein phosphorylation on heme metabolism in human hepatic cells: induction of delta-aminolevulinic synthase mRNA and protein by okadaic acid. DNA Cell Biol (2002) 0.75
trans-Complementation of HBV rtM204I mutant replication by HBV wild-type polymerase. Virology (2009) 0.75