Recurrent chemical reactivations of EBV promotes genome instability and enhances tumor progression of nasopharyngeal carcinoma cells.

PubWeight™: 1.02‹?› | Rank: Top 15%

🔗 View Article (PMID 19132751)

Published in Int J Cancer on May 01, 2009

Authors

Chih-Yeu Fang1, Chia-Huei Lee, Chung-Chun Wu, Yu-Ting Chang, Shu-Ling Yu, Sheng-Ping Chou, Ping-Ting Huang, Chi-Long Chen, Jia-Woei Hou, Yao Chang, Ching-Hwa Tsai, Kenzo Takada, Jen-Yang Chen

Author Affiliations

1: National Institute of Cancer Research, National Health Research Institutes, Zhunan, Taiwan.

Articles citing this

The role of Epstein-Barr virus in epithelial malignancies. J Pathol (2015) 1.11

Epstein-Barr virus DNase (BGLF5) induces genomic instability in human epithelial cells. Nucleic Acids Res (2009) 0.96

Epstein-Barr virus BGLF4 kinase retards cellular S-phase progression and induces chromosomal abnormality. PLoS One (2012) 0.86

EGCG inhibits proliferation, invasiveness and tumor growth by up-regulation of adhesion molecules, suppression of gelatinases activity, and induction of apoptosis in nasopharyngeal carcinoma cells. Int J Mol Sci (2015) 0.85

The synergistic effect of chemical carcinogens enhances Epstein-Barr virus reactivation and tumor progression of nasopharyngeal carcinoma cells. PLoS One (2012) 0.84

Epstein-Barr virus BALF3 mediates genomic instability and progressive malignancy in nasopharyngeal carcinoma. Oncotarget (2014) 0.84

How virus persistence can initiate the tumorigenesis process. World J Virol (2013) 0.84

A novel statistical prognostic score model that includes serum CXCL5 levels and clinical classification predicts risk of disease progression and survival of nasopharyngeal carcinoma patients. PLoS One (2013) 0.83

Epstein-Barr virus Zta upregulates matrix metalloproteinases 3 and 9 that synergistically promote cell invasion in vitro. PLoS One (2013) 0.79

The biological properties of different Epstein-Barr virus strains explain their association with various types of cancers. Oncotarget (2016) 0.79

Epstein-Barr virus BZLF1 protein impairs accumulation of host DNA damage proteins at damage sites in response to DNA damage. Lab Invest (2015) 0.78

DNA Damage Signaling Is Induced in the Absence of Epstein-Barr Virus (EBV) Lytic DNA Replication and in Response to Expression of ZEBRA. PLoS One (2015) 0.78

Inhibitory activities of microalgal extracts against Epstein-Barr virus DNA release from lymphoblastoid cells. J Zhejiang Univ Sci B (2011) 0.77

EBV reactivation as a target of luteolin to repress NPC tumorigenesis. Oncotarget (2016) 0.77

High cell density and latent membrane protein 1 expression induce cleavage of the mixed lineage leukemia gene at 11q23 in nasopharyngeal carcinoma cell line. J Biomed Sci (2010) 0.76

Epstein-Barr virus infection and nasopharyngeal carcinoma. Philos Trans R Soc Lond B Biol Sci (2017) 0.75

Identification of Novel Small Organic Compounds with Diverse Structures for the Induction of Epstein-Barr Virus (EBV) Lytic Cycle in EBV-Positive Epithelial Malignancies. PLoS One (2015) 0.75

Inhibition of Epstein-Barr virus reactivation by the flavonoid apigenin. J Biomed Sci (2017) 0.75

WTC-01, a novel synthetic oxime-flavone compound, destabilizes microtubules in human nasopharyngeal carcinoma cells in vitro and in vivo. Br J Pharmacol (2015) 0.75

Epstein-Barr virus lytic reactivation regulation and its pathogenic role in carcinogenesis. Int J Biol Sci (2016) 0.75

Bortezomib promotes KHSV and EBV lytic cycle by activating JNK and autophagy. Sci Rep (2017) 0.75

Allelic imbalance and abnormal expression of FHIT in endemic nasopharyngeal carcinoma: association with clinicopathological features. Eur Arch Otorhinolaryngol (2010) 0.75

Articles by these authors

EB virus-encoded RNAs are recognized by RIG-I and activate signaling to induce type I IFN. EMBO J (2006) 2.51

Activation of DNA methyltransferase 1 by EBV latent membrane protein 2A leads to promoter hypermethylation of PTEN gene in gastric carcinoma. Cancer Res (2009) 1.99

Nationwide survey of hemophagocytic lymphohistiocytosis in Japan. Int J Hematol (2007) 1.90

Epstein-Barr virus RNA confers resistance to interferon-alpha-induced apoptosis in Burkitt's lymphoma. EMBO J (2002) 1.89

Detection of severe acute respiratory syndrome-associated coronavirus in pneumocytes of the lung. Am J Clin Pathol (2004) 1.71

Expression of viral microRNAs in Epstein-Barr virus-associated gastric carcinoma. J Virol (2006) 1.62

Systemic human orbital fat-derived stem/stromal cell transplantation ameliorates acute inflammation in lipopolysaccharide-induced acute lung injury. Crit Care Med (2012) 1.60

Epstein-Barr virus (EBV)-encoded small RNA is released from EBV-infected cells and activates signaling from Toll-like receptor 3. J Exp Med (2009) 1.60

The effectiveness of silver-releasing dressings in the management of non-healing chronic wounds: a meta-analysis. J Clin Nurs (2009) 1.59

Editing of Epstein-Barr virus-encoded BART6 microRNAs controls their dicer targeting and consequently affects viral latency. J Biol Chem (2010) 1.59

Classification of Epstein-Barr virus-positive gastric cancers by definition of DNA methylation epigenotypes. Cancer Res (2011) 1.57

Establishment of a young mouse model and identification of an allelic variation of zmpB in complicated pneumonia caused by Streptococcus pneumoniae. Crit Care Med (2008) 1.50

Long-term follow-up of ulcerative colitis in Taiwan. J Chin Med Assoc (2012) 1.48

SOX9 expression and its methylation status in gastric cancer. Virchows Arch (2012) 1.47

DNA methyltransferase inhibition restores erythropoietin production in fibrotic murine kidneys. J Clin Invest (2016) 1.47

Spectrum of MLL2 (ALR) mutations in 110 cases of Kabuki syndrome. Am J Med Genet A (2011) 1.43

Activation of DNA methyltransferase 1 by EBV LMP1 Involves c-Jun NH(2)-terminal kinase signaling. Cancer Res (2006) 1.38

Epstein-Barr virus latent membrane protein 1 induces micronucleus formation, represses DNA repair and enhances sensitivity to DNA-damaging agents in human epithelial cells. Oncogene (2004) 1.38

Syk tyrosine kinase mediates Epstein-Barr virus latent membrane protein 2A-induced cell migration in epithelial cells. J Biol Chem (2006) 1.37

Epstein-Barr virus infection alters cellular signal cascades in human nasopharyngeal epithelial cells. Neoplasia (2006) 1.37

Long-term results of anti-Helicobacter pylori therapy in early-stage gastric high-grade transformed MALT lymphoma. J Natl Cancer Inst (2005) 1.35

Tumor necrosis factor-alpha and interleukin-10 promoter polymorphisms in Epstein-Barr virus-associated gastric carcinoma. J Infect Dis (2001) 1.35

Nasopharyngeal carcinoma and genetic polymorphisms of DNA repair enzymes XRCC1 and hOGG1. Cancer Epidemiol Biomarkers Prev (2003) 1.33

Epstein-Barr virus nuclear protein EBNA3C is required for cell cycle progression and growth maintenance of lymphoblastoid cells. Proc Natl Acad Sci U S A (2006) 1.33

Epstein-Barr virus-encoded LMP2A regulates viral and cellular gene expression by modulation of the NF-kappaB transcription factor pathway. Proc Natl Acad Sci U S A (2004) 1.32

Critical role of Epstein-Barr Virus (EBV)-encoded RNA in efficient EBV-induced B-lymphocyte growth transformation. J Virol (2005) 1.32

Epstein-Barr virus BGLF4 kinase induces disassembly of the nuclear lamina to facilitate virion production. J Virol (2008) 1.31

Autocrine growth of Epstein-Barr virus-positive gastric carcinoma cells mediated by an Epstein-Barr virus-encoded small RNA. Cancer Res (2003) 1.31

Downregulation of microRNA-200 in EBV-associated gastric carcinoma. Cancer Res (2010) 1.25

Epstein-Barr virus BZLF1 gene, a switch from latency to lytic infection, is expressed as an immediate-early gene after primary infection of B lymphocytes. J Virol (2006) 1.24

Epstein-Barr virus-encoded small RNA induces insulin-like growth factor 1 and supports growth of nasopharyngeal carcinoma-derived cell lines. Oncogene (2005) 1.24

Epstein-Barr virus (EBV)-encoded BARF1 gene is expressed in nasopharyngeal carcinoma and EBV-associated gastric carcinoma tissues in the absence of lytic gene expression. J Med Virol (2005) 1.23

T-cell regulatory gene CTLA-4 polymorphism/haplotype association with autoimmune pancreatitis. Clin Chem (2007) 1.21

Detection of Epstein-Barr virus BGLF4 protein kinase in virus replication compartments and virus particles. J Gen Virol (2005) 1.21

Production of high-titer Epstein-Barr virus recombinants derived from Akata cells by using a bacterial artificial chromosome system. J Virol (2004) 1.20

TLR9 contributes to the recognition of EBV by primary monocytes and plasmacytoid dendritic cells. J Immunol (2010) 1.19

Epstein-Barr virus nuclear antigens 3C and 3A maintain lymphoblastoid cell growth by repressing p16INK4A and p14ARF expression. Proc Natl Acad Sci U S A (2011) 1.18

Prospective measurement of Epstein-Barr virus-DNA in plasma and peripheral blood mononuclear cells of extranodal NK/T-cell lymphoma, nasal type. Blood (2011) 1.17

Epstein-Barr virus (EBV)-encoded RNA promotes growth of EBV-infected T cells through interleukin-9 induction. Cancer Res (2004) 1.17

Epstein-Barr virus (EBV) genome and expression in breast cancer tissue: effect of EBV infection of breast cancer cells on resistance to paclitaxel (Taxol). J Virol (2006) 1.16

Cyclin D1 overexpression supports stable EBV infection in nasopharyngeal epithelial cells. Proc Natl Acad Sci U S A (2012) 1.15

Symmetrical localization of extrachromosomally replicating viral genomes on sister chromatids. J Cell Sci (2007) 1.13

Epstein-Barr virus seroreactivity among unaffected individuals within high-risk nasopharyngeal carcinoma families in Taiwan. Int J Cancer (2004) 1.13

Epstein-Barr virus latent membrane protein 2A regulates c-Jun protein through extracellular signal-regulated kinase. J Virol (2002) 1.13

Increase of programmed death-1-expressing intratumoral CD8 T cells predicts a poor prognosis for nasopharyngeal carcinoma. Mod Pathol (2010) 1.12

Multiple-dose safety, tolerability, and pharmacokinetics of oral nemonoxacin (TG-873870) in healthy volunteers. Antimicrob Agents Chemother (2009) 1.12

Epstein-Barr-virus-encoded LMP2A induces primary epithelial cell migration and invasion: possible role in nasopharyngeal carcinoma metastasis. J Virol (2005) 1.12

Epstein-Barr virus BGLF4 kinase suppresses the interferon regulatory factor 3 signaling pathway. J Virol (2008) 1.11

Role of EBERs in the pathogenesis of EBV infection. Adv Cancer Res (2010) 1.11

Epstein-Barr virus BGLF4 kinase induces premature chromosome condensation through activation of condensin and topoisomerase II. J Virol (2007) 1.11

Induction of the early growth response 1 gene by Epstein-Barr virus lytic transactivator Zta. J Virol (2006) 1.11

Rsf-1, a chromatin remodeling protein, induces DNA damage and promotes genomic instability. J Biol Chem (2010) 1.10

A novel animal model of Epstein-Barr virus-associated hemophagocytic lymphohistiocytosis in humanized mice. Blood (2011) 1.10

Human SCARB2 transgenic mice as an infectious animal model for enterovirus 71. PLoS One (2013) 1.10

Primary pleural angiosarcoma as a mimicker of mesothelioma: a case report **VS**. Diagn Pathol (2011) 1.09

Human B cells immortalized with Epstein-Barr virus upregulate CCR6 and CCR10 and downregulate CXCR4 and CXCR5. J Virol (2002) 1.08

Epstein-Barr virus nuclear protein EBNA3C residues critical for maintaining lymphoblastoid cell growth. Proc Natl Acad Sci U S A (2009) 1.07

Efficacy and safety of nemonoxacin versus levofloxacin for community-acquired pneumonia. Antimicrob Agents Chemother (2010) 1.05

Malignant transformation of Epstein-Barr virus-negative Akata cells by introduction of the BARF1 gene carried by Epstein-Barr virus. J Virol (2003) 1.05

Regulation of matrix metalloproteinase-1 by Epstein-Barr virus proteins. Cancer Res (2003) 1.05

Endoplasmic reticulum stress triggers XBP-1-mediated up-regulation of an EBV oncoprotein in nasopharyngeal carcinoma. Cancer Res (2009) 1.04

Variation of the killer cell immunoglobulin-like receptors and HLA-C genes in nasopharyngeal carcinoma. Cancer Epidemiol Biomarkers Prev (2005) 1.03

Epstein-Barr virus-encoded poly(A)- RNA confers resistance to apoptosis mediated through Fas by blocking the PKR pathway in human epithelial intestine 407 cells. J Virol (2005) 1.03

Epstein-Barr virus latent membrane protein 2A promotes invasion of nasopharyngeal carcinoma cells through ERK/Fra-1-mediated induction of matrix metalloproteinase 9. J Virol (2012) 1.03

Epstein-Barr virus infection in immortalized nasopharyngeal epithelial cells: regulation of infection and phenotypic characterization. Int J Cancer (2010) 1.02

Epstein-Barr virus lytic transactivator Zta enhances chemotactic activity through induction of interleukin-8 in nasopharyngeal carcinoma cells. J Virol (2008) 1.02

Adiponectin as a potential differential marker to distinguish pancreatic cancer and chronic pancreatitis. Pancreas (2007) 1.02

Role of Twist in head and neck carcinoma with lymph node metastasis. Anticancer Res (2008) 1.02

A study of grid artifacts formation and elimination in computed radiographic images. J Digit Imaging (2006) 1.02

Independent effect of EBV and cigarette smoking on nasopharyngeal carcinoma: a 20-year follow-up study on 9,622 males without family history in Taiwan. Cancer Epidemiol Biomarkers Prev (2009) 1.01

The ESCRT machinery is recruited by the viral BFRF1 protein to the nucleus-associated membrane for the maturation of Epstein-Barr Virus. PLoS Pathog (2012) 1.01

Effect of phosphorylation on the transactivation activity of Epstein-Barr virus BMRF1, a major target of the viral BGLF4 kinase. J Gen Virol (2008) 1.01

Epstein-Barr virus (EBV)-encoded RNA 2 (EBER2) but not EBER1 plays a critical role in EBV-induced B-cell growth transformation. J Virol (2007) 1.00

Roles of cell signaling pathways in cell-to-cell contact-mediated Epstein-Barr virus transmission. J Virol (2012) 1.00

EBV-expressing AGS gastric carcinoma cell sublines present increased motility and invasiveness. Int J Cancer (2002) 1.00

Epstein-Barr virus LMP1 inhibits the expression of SAP gene and upregulates Th1 cytokines in the pathogenesis of hemophagocytic syndrome. Blood (2005) 1.00

Identification of a novel protein 3a from severe acute respiratory syndrome coronavirus. FEBS Lett (2004) 0.99

Genome-wide transcription program and expression of the Rta responsive gene of Epstein-Barr virus. Virology (2005) 0.99

The role of Epstein-Barr virus-encoded small RNAs (EBERs) in oncogenesis. Rev Med Virol (2002) 0.99

Variable expressivity in Patau syndrome is not all related to trisomy 13 mosaicism. Am J Med Genet A (2007) 0.99

Infection of HHV-8+ primary effusion lymphoma cells with a recombinant Epstein-Barr virus leads to restricted EBV latency, altered phenotype, and increased tumorigenicity without affecting TCL1 expression. Blood (2003) 0.99

Human cellular protein VRK2 interacts specifically with Epstein-Barr virus BHRF1, a homologue of Bcl-2, and enhances cell survival. J Gen Virol (2006) 0.98

Novel nuclear export signal-interacting protein, NESI, critical for the assembly of hepatitis delta virus. J Virol (2005) 0.98

Epstein-Barr virus transforming protein LMP1 plays a critical role in virus production. J Virol (2005) 0.98

Incidence, endoscopic morphology and distribution of metastatic lesions in the gastrointestinal tract. J Gastroenterol Hepatol (2007) 0.98

Epstein-Barr virus nuclear protein 3C domains necessary for lymphoblastoid cell growth: interaction with RBP-Jkappa regulates TCL1. J Virol (2009) 0.98

Association of the -160 C --> a promoter polymorphism of E-cadherin gene with gastric carcinoma risk. Cancer (2002) 0.98

Role of the TSG101 gene in Epstein-Barr virus late gene transcription. J Virol (2006) 0.98

Metastatic hepatocellular carcinoma in the nasal septum: report of a case. J Formos Med Assoc (2002) 0.97

Epstein-Barr virus nuclear antigen 1 is a DNA-binding protein with strong RNA-binding activity. J Gen Virol (2004) 0.97