Published in J Biol Chem on January 09, 2009
JMJD2A contributes to breast cancer progression through transcriptional repression of the tumor suppressor ARHI. Breast Cancer Res (2014) 1.47
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Building the actin cytoskeleton: filopodia contribute to the construction of contractile bundles in the lamella. J Cell Biol (2008) 1.70
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Mechanisms in LPA-induced tumor cell migration: critical role of phosphorylated ERK. J Cell Sci (2003) 1.51
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PAK5, a new brain-specific kinase, promotes neurite outgrowth in N1E-115 cells. Mol Cell Biol (2002) 1.49
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Ca2+ influx through L-type Ca2+ channels controls the trailing tail contraction in growth factor-induced fibroblast cell migration. J Biol Chem (2005) 1.36
p21-activated Kinase 1 (Pak1)-dependent phosphorylation of Raf-1 regulates its mitochondrial localization, phosphorylation of BAD, and Bcl-2 association. J Biol Chem (2005) 1.34
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The MEK1 scaffolding protein MP1 regulates cell spreading by integrating PAK1 and Rho signals. Mol Cell Biol (2005) 1.34
Signal cross talks for sustained MAPK activation and cell migration: the potential role of reactive oxygen species. Cancer Metastasis Rev (2008) 1.30
The p21-activated kinase PAK is negatively regulated by POPX1 and POPX2, a pair of serine/threonine phosphatases of the PP2C family. Curr Biol (2002) 1.30
The integrin-binding protein Nischarin regulates cell migration by inhibiting PAK. EMBO J (2004) 1.25
Emerging functions of p21-activated kinases in human cancer cells. J Cell Physiol (2002) 1.25
Mechanism of p21-activated kinase 6-mediated inhibition of androgen receptor signaling. J Biol Chem (2003) 1.24
Bombesin, lysophosphatidic acid, and epidermal growth factor rapidly stimulate focal adhesion kinase phosphorylation at Ser-910: requirement for ERK activation. J Biol Chem (2003) 1.21
Cooperativity between the Ras-ERK and Rho-Rho kinase pathways in urokinase-type plasminogen activator-stimulated cell migration. J Biol Chem (2002) 1.17
Adhesion stimulates direct PAK1/ERK2 association and leads to ERK-dependent PAK1 Thr212 phosphorylation. J Biol Chem (2004) 1.06
Temporal and quantitative regulation of mitogen-activated protein kinase (MAPK) modulates cell motility and invasion. Oncogene (2001) 1.03
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Trihydrophobin 1 is a new negative regulator of A-Raf kinase. J Biol Chem (2003) 0.81
Ubiquitin-dependent proteolysis of trihydrophobin 1 (TH1) by the human papilloma virus E6-associated protein (E6-AP). J Cell Biochem (2007) 0.80
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PWT-458, a novel pegylated-17-hydroxywortmannin, inhibits phosphatidylinositol 3-kinase signaling and suppresses growth of solid tumors. Cancer Biol Ther (2005) 1.70
Fabrication of cell microintegrated blood vessel constructs through electrohydrodynamic atomization. Biomaterials (2007) 1.34
MicroRNA-449 and microRNA-34b/c function redundantly in murine testes by targeting E2F transcription factor-retinoblastoma protein (E2F-pRb) pathway. J Biol Chem (2012) 1.31
Pericyte-based human tissue engineered vascular grafts. Biomaterials (2010) 1.25
A bilayered elastomeric scaffold for tissue engineering of small diameter vascular grafts. Acta Biomater (2009) 1.20
Hepatitis B virus X protein blunts senescence-like growth arrest of human hepatocellular carcinoma by reducing Notch1 cleavage. Hepatology (2010) 1.19
Tissue-to-cellular level deformation coupling in cell micro-integrated elastomeric scaffolds. Biomaterials (2008) 1.18
Hybrid inhibitors of phosphatidylinositol 3-kinase (PI3K) and the mammalian target of rapamycin (mTOR): design, synthesis, and superior antitumor activity of novel wortmannin-rapamycin conjugates. J Med Chem (2010) 1.17
Cyclin D3/CDK11p58 complex is involved in the repression of androgen receptor. Mol Cell Biol (2007) 1.16
Surgical results of anterior corpectomy in the aged patients with cervical myelopathy. Eur Spine J (2007) 1.15
In vivo assessment of a tissue-engineered vascular graft combining a biodegradable elastomeric scaffold and muscle-derived stem cells in a rat model. Tissue Eng Part A (2010) 1.14
Ribosomal RACK1 promotes chemoresistance and growth in human hepatocellular carcinoma. J Clin Invest (2012) 1.11
Transient elastic support for vein grafts using a constricting microfibrillar polymer wrap. Biomaterials (2008) 1.10
Use of adenovirus-delivered siRNA to target oncoprotein p28GANK in hepatocellular carcinoma. Gastroenterology (2005) 1.09
Proteomic analysis of hepatitis B virus-associated hepatocellular carcinoma: Identification of potential tumor markers. Proteomics (2005) 1.08
Accurate qualitative and quantitative proteomic analysis of clinical hepatocellular carcinoma using laser capture microdissection coupled with isotope-coded affinity tag and two-dimensional liquid chromatography mass spectrometry. Mol Cell Proteomics (2004) 1.07
Interaction of p58(PITSLRE), a G2/M-specific protein kinase, with cyclin D3. J Biol Chem (2002) 1.06
Hepatitis B virus large surface antigen promotes liver carcinogenesis by activating the Src/PI3K/Akt pathway. Cancer Res (2011) 1.05
Morphological and mechanical characteristics of the reconstructed rat abdominal wall following use of a wet electrospun biodegradable polyurethane elastomer scaffold. Biomaterials (2010) 1.04
Proteome analysis of hepatocellular carcinoma by laser capture microdissection. Proteomics (2006) 1.02
Snail is an independent prognostic predictor for progression and patient survival of gastric cancer. Cancer Sci (2012) 1.01
Thermally responsive injectable hydrogel incorporating methacrylate-polylactide for hydrolytic lability. Biomacromolecules (2010) 1.00
Hepatitis B virus X protein confers resistance of hepatoma cells to anoikis by up-regulating and activating p21-activated kinase 1. Gastroenterology (2012) 1.00
Regulation of spindle and chromatin dynamics during early and late stages of oocyte maturation by aurora kinases. Mol Hum Reprod (2008) 1.00
MicroRNA-185 suppresses proliferation, invasion, migration, and tumorigenicity of human prostate cancer cells through targeting androgen receptor. Mol Cell Biochem (2013) 0.99
Protein-reactive, thermoresponsive copolymers with high flexibility and biodegradability. Biomacromolecules (2008) 0.99
Elastomeric electrospun polyurethane scaffolds: the interrelationship between fabrication conditions, fiber topology, and mechanical properties. Adv Mater (2011) 0.98
Pegylated wortmannin and 17-hydroxywortmannin conjugates as phosphoinositide 3-kinase inhibitors active in human tumor xenograft models. J Med Chem (2006) 0.98
Elevated beta1,4-galactosyltransferase I in highly metastatic human lung cancer cells. Identification of E1AF as important transcription activator. J Biol Chem (2004) 0.95
Klotho endows hepatoma cells with resistance to anoikis via VEGFR2/PAK1 activation in hepatocellular carcinoma. PLoS One (2013) 0.95
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ATF5 increases cisplatin-induced apoptosis through up-regulation of cyclin D3 transcription in HeLa cells. Biochem Biophys Res Commun (2005) 0.94
Microstructural manipulation of electrospun scaffolds for specific bending stiffness for heart valve tissue engineering. Acta Biomater (2012) 0.93
Lectin-like oxidized low-density lipoprotein receptor-1 delivers heat shock protein 60-fused antigen into the MHC class I presentation pathway. J Immunol (2010) 0.93
Measurement of hydroxyapatite density and Knoop hardness in sound human enamel and a correlational analysis between them. Arch Oral Biol (2010) 0.93
Hepatitis B virus X protein promotes hepatoma cell invasion and metastasis by stabilizing Snail protein. Cancer Sci (2012) 0.92
In vivo performance of a phospholipid-coated bioerodable elastomeric graft for small-diameter vascular applications. J Biomed Mater Res A (2010) 0.92
N-acetylglucosaminyltransferase V confers hepatoma cells with resistance to anoikis through EGFR/PAK1 activation. Glycobiology (2013) 0.92
Induction of apoptosis by p110C requires mitochondrial translocation of the proapoptotic BCL-2 family member BAD. FEBS Lett (2006) 0.91
Effects of Nidus Vespae extract and chemical fractions on glucosyltransferases, adherence and biofilm formation of Streptococcus mutans. Arch Oral Biol (2007) 0.91
Quantitative analysis of serum IgG galactosylation assists differential diagnosis of ovarian cancer. J Proteome Res (2013) 0.91
Biodegradable polyurethane ureas with variable polyester or polycarbonate soft segments: effects of crystallinity, molecular weight, and composition on mechanical properties. Biomacromolecules (2011) 0.91
Up-regulation of RACK1 by TGF-β1 promotes hepatic fibrosis in mice. PLoS One (2013) 0.90
Non-invasive characterization of polyurethane-based tissue constructs in a rat abdominal repair model using high frequency ultrasound elasticity imaging. Biomaterials (2013) 0.90
Mineral densities and elemental content in different layers of healthy human enamel with varying teeth age. Arch Oral Biol (2011) 0.89
Singapore familial adenomatous polyposis (FAP) patients with classical adenomatous polyposis but undetectable APC mutations have accelerated cancer progression. Am J Gastroenterol (2006) 0.89
The C-terminal kinase domain of the p34cdc2-related PITSLRE protein kinase (p110C) associates with p21-activated kinase 1 and inhibits its activity during anoikis. J Biol Chem (2003) 0.89
Alpha2,3-Sialylation regulates the stability of stem cell marker CD133. J Biochem (2010) 0.89
Combined anti-tumor effects of IFN-α and sorafenib on hepatocellular carcinoma in vitro and in vivo. Biochem Biophys Res Commun (2012) 0.88
Protein kinases D2 and D3 are novel growth regulators in HCC1806 triple-negative breast cancer cells. Anticancer Res (2013) 0.88
Sorafenib suppresses growth and survival of hepatoma cells by accelerating degradation of enhancer of zeste homolog 2. Cancer Sci (2013) 0.88
Cyclin D3 interacts with human activating transcription factor 5 and potentiates its transcription activity. Biochem Biophys Res Commun (2004) 0.88
Knockdown of BCL2L12 leads to cisplatin resistance in MDA-MB-231 breast cancer cells. Biochim Biophys Acta (2008) 0.88
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Effect of compounds of Galla chinensis and their combined effects with fluoride on remineralization of initial enamel lesion in vitro. J Dent (2008) 0.87
CDK11p58 represses vitamin D receptor-mediated transcriptional activation through promoting its ubiquitin-proteasome degradation. Biochem Biophys Res Commun (2009) 0.87
Cdc34-mediated degradation of ATF5 is blocked by cisplatin. J Biol Chem (2008) 0.87
SGT, a Hsp90beta binding partner, is accumulated in the nucleus during cell apoptosis. Biochem Biophys Res Commun (2006) 0.87
Thr-370 is responsible for CDK11(p58) autophosphorylation, dimerization, and kinase activity. J Biol Chem (2010) 0.87
Competition between yogurt probiotics and periodontal pathogens in vitro. Acta Odontol Scand (2010) 0.86
The oncogenic role of EIF3D is associated with increased cell cycle progression and motility in prostate cancer. Med Oncol (2015) 0.86
Discovering multiple transcripts of human hepatocytes using massively parallel signature sequencing (MPSS). BMC Genomics (2007) 0.86
Down-regulation of beta1,4GalT V at protein level contributes to arsenic trioxide-induced glioma cell apoptosis. Cancer Lett (2008) 0.86
Molecular characterization of two novel isoforms and a soluble form of mouse CLEC-2. Biochem Biophys Res Commun (2008) 0.86
Laminarin-mediated targeting to Dectin-1 enhances antigen-specific immune responses. Biochem Biophys Res Commun (2009) 0.85
Increase of macrophage migration inhibitory factor (MIF) expression in cardiomyocytes during chronic hypoxia. Clin Chim Acta (2009) 0.85
Cyclin D3 interacts with vitamin D receptor and regulates its transcription activity. Biochem Biophys Res Commun (2005) 0.85
Role of MUC20 overexpression as a predictor of recurrence and poor outcome in colorectal cancer. J Transl Med (2013) 0.85
Repression of estrogen receptor alpha by CDK11p58 through promoting its ubiquitin-proteasome degradation. J Biochem (2009) 0.85
Overexpression of small glutamine-rich TPR-containing protein promotes apoptosis in 7721 cells. FEBS Lett (2005) 0.85
Microglial LOX-1 reacts with extracellular HSP60 to bridge neuroinflammation and neurotoxicity. Neurochem Int (2012) 0.85
Histone H3 (lys-9) deacetylation is associated with transcriptional silencing of E-cadherin in colorectal cancer cell lines. Cancer Invest (2008) 0.85
beta-Glucan oligosaccharide enhances CD8(+) T cells immune response induced by a DNA vaccine encoding hepatitis B virus core antigen. J Biomed Biotechnol (2010) 0.85
Down-regulation of the expression of beta1,4-galactosyltransferase V promotes integrin beta1 maturation. Biochem Biophys Res Commun (2006) 0.84
Sox2 is translationally activated by eukaryotic initiation factor 4E in human glioma-initiating cells. Biochem Biophys Res Commun (2010) 0.84
Identification of dynein light chain 2 as an interaction partner of p21-activated kinase 1. Biochem Biophys Res Commun (2005) 0.84
Biodegradable elastic patch plasty ameliorates left ventricular adverse remodeling after ischemia-reperfusion injury: a preclinical study of a porous polyurethane material in a porcine model. J Thorac Cardiovasc Surg (2012) 0.84
E1AF promotes breast cancer cell cycle progression via upregulation of Cyclin D3 transcription. Biochem Biophys Res Commun (2007) 0.84