Published in Eur J Clin Pharmacol on February 11, 2009
Autonomic and hemodynamic origins of pre-hypertension: central role of heredity. J Am Coll Cardiol (2012) 1.59
Targeting microglia-mediated neurotoxicity: the potential of NOX2 inhibitors. Cell Mol Life Sci (2012) 1.14
Sequence diversity in CYP3A promoters and characterization of the genetic basis of polymorphic CYP3A5 expression. Nat Genet (2001) 5.80
Increased risk of atherothrombotic events associated with cytochrome P450 3A5 polymorphism in patients taking clopidogrel. CMAJ (2006) 2.01
Clinical review: Prevention and therapy of vasospasm in subarachnoid hemorrhage. Crit Care (2007) 1.42
Effect of the mutation (C3435T) at exon 26 of the MDR1 gene on expression level of MDR1 messenger ribonucleic acid in duodenal enterocytes of healthy Japanese subjects. Clin Pharmacol Ther (2002) 1.30
Nimodipine. A review of its pharmacodynamic and pharmacokinetic properties, and therapeutic potential in cerebrovascular disease. Drugs (1989) 1.25
Nimodipine for primary degenerative, mixed and vascular dementia. Cochrane Database Syst Rev (2002) 1.21
Nimodipine and its use in cerebrovascular disease: evidence from recent preclinical and controlled clinical studies. Clin Exp Hypertens (2008) 1.14
CACNA1C polymorphisms are associated with the efficacy of calcium channel blockers in the treatment of hypertension. Pharmacogenomics (2006) 1.01
The effect of CYP3A5 and MDR1 polymorphic expression on cyclosporine oral disposition in renal transplant patients. J Clin Pharmacol (2003) 1.00
CYP3A5 genotype did not impact on nifedipine disposition in healthy volunteers. Pharmacogenomics J (2004) 1.00
Influence of CYP3A5 genotype on the pharmacokinetics and pharmacodynamics of the cytochrome P4503A probes alfentanil and midazolam. Clin Pharmacol Ther (2007) 0.99
Pharmacogenetics of antihypertensive treatment. Vascul Pharmacol (2005) 0.97
Combined nimodipine and citicoline reduce infarct size, attenuate apoptosis and increase bcl-2 expression after focal cerebral ischemia. Neuroscience (2003) 0.95
Differential effects of valproic acid and enzyme-inducing anticonvulsants on nimodipine pharmacokinetics in epileptic patients. Br J Clin Pharmacol (1991) 0.93
Effect of ABCB1 (MDR1) haplotypes derived from G2677T/C3435T on the pharmacokinetics of amlodipine in healthy subjects. Br J Clin Pharmacol (2006) 0.90
Detection of MDR1 single nucleotide polymorphisms C3435T and G2677T using real-time polymerase chain reaction: MDR1 single nucleotide polymorphism genotyping assay. AAPS PharmSci (2002) 0.89
Effect of CYP3A5*3 genotype on the pharmacokinetics and pharmacodynamics of amlodipine in healthy Korean subjects. Clin Pharmacol Ther (2006) 0.83
Enzyme kinetics and inhibition of nimodipine metabolism in human liver microsomes. Acta Pharmacol Sin (2000) 0.82
Cytochrome P450 3A5 genotype is associated with verapamil response in healthy subjects. Clin Pharmacol Ther (2007) 0.82
Evidence-based pharmacotherapy for cerebral vasospasm. Neurol Res (2008) 0.81
Nimodipine restores the altered hippocampal phenytoin pharmacokinetics in a refractory epileptic model. Neurosci Lett (2007) 0.81
Interaction of digoxin with antihypertensive drugs via MDR1. Life Sci (2002) 0.79
P-glycoprotein restricted transport of nimodipine across blood-brain barrier. Acta Pharmacol Sin (2003) 0.77
Effect of P-glycoprotein inhibitors erythromycin and cyclosporin A on brain pharmacokinetics of nimodipine in rats. Eur J Drug Metab Pharmacokinet (2004) 0.75
Identification of ligands for DAF-12 that govern dauer formation and reproduction in C. elegans. Cell (2006) 3.82
Structure of the CCR5 chemokine receptor-HIV entry inhibitor maraviroc complex. Science (2013) 3.17
The hippo tumor pathway promotes TAZ degradation by phosphorylating a phosphodegron and recruiting the SCF{beta}-TrCP E3 ligase. J Biol Chem (2010) 2.27
MirSNP, a database of polymorphisms altering miRNA target sites, identifies miRNA-related SNPs in GWAS SNPs and eQTLs. BMC Genomics (2012) 1.61
TRF2 promotes multidrug resistance in gastric cancer cells. Cancer Biol Ther (2006) 1.57
Compound 49b prevents diabetes-induced apoptosis through increased IGFBP-3 levels. Invest Ophthalmol Vis Sci (2012) 1.46
Efficient incorporation of eukaryotic initiation factor 1 into the multifactor complex is critical for formation of functional ribosomal preinitiation complexes in vivo. J Biol Chem (2004) 1.43
The involvement of AMPA-ERK1/2-BDNF pathway in the mechanism of new antidepressant action of prokinetic meranzin hydrate. Amino Acids (2012) 1.41
Eukaryotic translation initiation factor 5 is critical for integrity of the scanning preinitiation complex and accurate control of GCN4 translation. Mol Cell Biol (2005) 1.34
Cepred: predicting the co-expression patterns of the human intronic microRNAs with their host genes. PLoS One (2009) 1.27
Genome biology of Actinobacillus pleuropneumoniae JL03, an isolate of serotype 3 prevalent in China. PLoS One (2008) 1.23
Comparative genomic characterization of Actinobacillus pleuropneumoniae. J Bacteriol (2010) 1.22
MicroRNA-195-5p suppresses glucose uptake and proliferation of human bladder cancer T24 cells by regulating GLUT3 expression. FEBS Lett (2012) 1.20
Chemopreventive effects of heat-processed Panax quinquefolius root on human breast cancer cells. Anticancer Res (2008) 1.20
Music therapy for people with schizophrenia and schizophrenia-like disorders. Cochrane Database Syst Rev (2011) 1.20
The association between a genetic polymorphism of coproporphyrinogen oxidase, dental mercury exposure and neurobehavioral response in humans. Neurotoxicol Teratol (2005) 1.17
Hospital pharmacists' knowledge and opinions regarding adverse drug reaction reporting in Northern China. Pharmacoepidemiol Drug Saf (2010) 1.17
Chronic low-level mercury exposure, BDNF polymorphism, and associations with cognitive and motor function. Neurotoxicol Teratol (2005) 1.15
PP1 cooperates with ASPP2 to dephosphorylate and activate TAZ. J Biol Chem (2010) 1.15
Change in nutritional status modulates the abundance of critical pre-initiation intermediate complexes during translation initiation in vivo. J Mol Biol (2007) 1.13
A mouse dry eye model induced by topical administration of benzalkonium chloride. Mol Vis (2011) 1.13
Detection of adulteration of notoginseng root extract with other panax species by quantitative HPLC coupled with PCA. J Agric Food Chem (2009) 1.10
Activation of c-Jun N-terminal protein kinase is a common mechanism underlying paraquat- and rotenone-induced dopaminergic cell apoptosis. Toxicol Sci (2007) 1.07
A novel polymyxin derivative that lacks the fatty acid tail and carries only three positive charges has strong synergism with agents excluded by the intact outer membrane. Antimicrob Agents Chemother (2010) 1.06
LXRβ is required for glucocorticoid-induced hyperglycemia and hepatosteatosis in mice. J Clin Invest (2010) 1.06
Novel antioxidant peptides from fermented mushroom Ganoderma lucidum. J Agric Food Chem (2004) 1.02
Characterization and promoter analysis of the mouse nestin gene. FEBS Lett (2004) 1.01
ASEB: a web server for KAT-specific acetylation site prediction. Nucleic Acids Res (2012) 0.99
Synthesis, characterization, and receptor interaction profiles of enantiomeric bile acids. J Med Chem (2007) 0.99
Increasing threat of brucellosis to low-risk persons in urban settings, China. Emerg Infect Dis (2014) 0.98
Design and synthesis of furoxan-based nitric oxide-releasing glucocorticoid derivatives with potent anti-inflammatory activity and improved safety. Bioorg Med Chem Lett (2006) 0.98
Human prostate cancer harbors the stem cell properties of bone marrow mesenchymal stem cells. Clin Cancer Res (2011) 0.97
Illusory motion due to causal time filtering. Vision Res (2009) 0.95
Src-stimulated IRTKS phosphorylation enhances cell migration. FEBS Lett (2011) 0.94
Enhanced biofilm formation and reduced virulence of Actinobacillus pleuropneumoniae luxS mutant. Microb Pathog (2008) 0.94
Ursolic acid promotes the neuroprotection by activating Nrf2 pathway after cerebral ischemia in mice. Brain Res (2012) 0.94
miR-372 down-regulates the oncogene ATAD2 to influence hepatocellular carcinoma proliferation and metastasis. BMC Cancer (2014) 0.94
Design, synthesis and evaluation of nitric oxide releasing derivatives of 3-n-butylphthalide as antiplatelet and antithrombotic agents. Org Biomol Chem (2011) 0.93
A mouse model of limbal stem cell deficiency induced by topical medication with the preservative benzalkonium chloride. Invest Ophthalmol Vis Sci (2013) 0.93
Hepatoprotective effects of Ganoderma lucidum peptides against D-galactosamine-induced liver injury in mice. J Ethnopharmacol (2008) 0.92
DNA sequencing of close to 1000 bases in 40 minutes by capillary electrophoresis using dimethyl sulfoxide and urea as denaturants in replaceable linear polyacrylamide solutions. Electrophoresis (2002) 0.92
Anti-angiogenic and anti-inflammatory effects of SERPINA3K on corneal injury. PLoS One (2011) 0.92
Endostar, a modified endostatin inhibits non small cell lung cancer cell in vitro invasion through osteopontin-related mechanism. Eur J Pharmacol (2009) 0.92
Hyperbaric oxygen preconditioning promotes angiogenesis in rat liver after partial hepatectomy. Life Sci (2008) 0.92
Framelet-based blind motion deblurring from a single image. IEEE Trans Image Process (2011) 0.92
High-performance liquid chromatography spectrometric analysis of trans-resveratrol in rat plasma. J Chromatogr B Analyt Technol Biomed Life Sci (2006) 0.92
A comprehensive analysis of GATA-1-regulated miRNAs reveals miR-23a to be a positive modulator of erythropoiesis. Nucleic Acids Res (2013) 0.91
A Fur-like protein PerR regulates two oxidative stress response related operons dpr and metQIN in Streptococcus suis. BMC Microbiol (2012) 0.91
Systematic identification and evolutionary features of rhesus monkey small nucleolar RNAs. BMC Genomics (2010) 0.91
Recent progress in predicting protein sub-subcellular locations. Expert Rev Proteomics (2011) 0.91
Astragaloside IV improved intracellular calcium handling in hypoxia-reoxygenated cardiomyocytes via the sarcoplasmic reticulum Ca-ATPase. Pharmacology (2008) 0.91
Antiproliferative effects of different plant parts of Panax notoginseng on SW480 human colorectal cancer cells. Phytother Res (2009) 0.90
Computational prediction of associations between long non-coding RNAs and proteins. BMC Genomics (2013) 0.90
Phosphorylation of caspase-7 by p21-activated protein kinase (PAK) 2 inhibits chemotherapeutic drug-induced apoptosis of breast cancer cell lines. J Biol Chem (2011) 0.90
Ethnic differences in distribution of serum prostate-specific antigen: a study in a healthy Chinese male population. Urology (2004) 0.90
hUbiquitome: a database of experimentally verified ubiquitination cascades in humans. Database (Oxford) (2011) 0.90
c-Maf is required for the development of dorsal horn laminae III/IV neurons and mechanoreceptive DRG axon projections. J Neurosci (2012) 0.90
Net greenhouse gas balance in China's Croplands over the last three decades and its mitigation potential. Environ Sci Technol (2014) 0.89
Sonic and desert hedgehog signaling in human fetal prostate development. Prostate (2007) 0.89
Role of virtues and perceived life stress in affecting psychological symptoms among Chinese college students. J Am Coll Health (2014) 0.89
A photometric high-throughput method for identification of electrochemically active bacteria using a WO3 nanocluster probe. Sci Rep (2013) 0.89
Studies on the antioxidant and hepatoprotective activities of polysaccharides from Talinum triangulare. J Ethnopharmacol (2011) 0.88
Gas-phase thermochemical properties of pyrimidine nucleobases. J Org Chem (2008) 0.87
Functional insight into the C-terminal extension of halolysin SptA from haloarchaeon Natrinema sp. J7. PLoS One (2011) 0.87
The expectorant activity of naringenin. Pulm Pharmacol Ther (2007) 0.87
Therapeutic effects of epidermal growth factor on benzalkonium chloride-induced dry eye in a mouse model. Invest Ophthalmol Vis Sci (2012) 0.87
Analysis on Actinobacillus pleuropneumoniae LuxS regulated genes reveals pleiotropic roles of LuxS/AI-2 on biofilm formation, adhesion ability and iron metabolism. Microb Pathog (2011) 0.86
The association between serotonin transporter gene promotor polymorphism (5-HTTLPR) and elemental mercury exposure on mood and behavior in humans. J Toxicol Environ Health A (2010) 0.86
The proteomic analysis of human neonatal umbilical cord serum by mass spectrometry. Acta Pharmacol Sin (2009) 0.86
Identification of GAS1 as an epirubicin resistance-related gene in human gastric cancer cells with a partially randomized small interfering RNA library. J Biol Chem (2009) 0.86
Leonurine protects brain injury by increased activities of UCP4, SOD, CAT and Bcl-2, decreased levels of MDA and Bax, and ameliorated ultrastructure of mitochondria in experimental stroke. Brain Res (2012) 0.86
PET imaging of Oatp-mediated hepatobiliary transport of [(11)C] rosuvastatin in the rat. Mol Pharm (2014) 0.86
Inhibition of high glucose-induced VEGF release in retinal ganglion cells by RNA interference targeting G protein-coupled receptor 91. Exp Eye Res (2013) 0.86
Comparative study on preparative methods of DC-Chol/DOPE liposomes and formulation optimization by determining encapsulation efficiency. Int J Pharm (2012) 0.86
Excellent selectivity for actinides with a tetradentate 2,9-diamide-1,10-phenanthroline ligand in highly acidic solution: a hard-soft donor combined strategy. Inorg Chem (2014) 0.86
Recombinant interferon-γ lentivirus co-infection inhibits adenovirus replication ex vivo. PLoS One (2012) 0.86
Accurate hierarchical control of hollow crossed NiCo2O4 nanocubes for superior lithium storage. Nanoscale (2014) 0.85
PCBP1 is required for maintenance of the transcriptionally silent state in fully grown mouse oocytes. Cell Cycle (2012) 0.85
Development of an LC-MS/MS assay to determine plasma pharmacokinetics of the radioprotectant octadecenyl thiophosphate (OTP) in monkeys. J Chromatogr B Analyt Technol Biomed Life Sci (2010) 0.85
The separate roles of endothelin receptors participate in remodeling of matrix metalloproteinase and connexin 43 of cardiac fibroblasts in maladaptive response to isoproterenol. Eur J Pharmacol (2010) 0.85
Association of HMGB1 and HMGB2 genetic polymorphisms with lung cancer chemotherapy response. Clin Exp Pharmacol Physiol (2014) 0.85
The thermodynamic analysis of protein stabilization by sucrose and glycerol against pressure-induced unfolding. Eur J Biochem (2003) 0.85
Alleviation of ovariectomy-induced osteoporosis in rats by Panax notoginseng saponins. J Nat Med (2010) 0.85
Overexpression of PML induced apoptosis in bladder cancer cell by caspase dependent pathway. Cancer Lett (2005) 0.85
Cardioprotective effects of Astragali Radix against isoproterenol-induced myocardial injury in rats and its possible mechanism. Phytother Res (2008) 0.85
Bioactive equivalence of combinatorial components identified in screening of an herbal medicine. Pharm Res (2014) 0.84
(S)-ZJM-289, a nitric oxide-releasing derivative of 3-n-butylphthalide, protects against ischemic neuronal injury by attenuating mitochondrial dysfunction and associated cell death. Neurochem Int (2011) 0.84
Protective effect of glycyrrhizin, glycyrrhetic acid and matrine on acute cholestasis induced by alpha-naphthyl isothiocyanate in rats. Planta Med (2007) 0.84
Anti-Asthmatic Effects of Ginsenoside Rb1 in a Mouse Model of Allergic Asthma Through Relegating Th1/Th2. Inflammation (2015) 0.84
Phosphoinositide 3-kinase p110δ mediates estrogen- and FSH-stimulated ovarian follicle growth. Mol Endocrinol (2013) 0.84
Improved solvent-free microwave extraction of essential oil from dried Cuminum cyminum L. and Zanthoxylum bungeanum Maxim. J Chromatogr A (2005) 0.84
NG, a novel PABA/NO-based oleanolic acid derivative, induces human hepatoma cell apoptosis via a ROS/MAPK-dependent mitochondrial pathway. Eur J Pharmacol (2012) 0.84
DAPT protects brain against cerebral ischemia by down-regulating the expression of Notch 1 and nuclear factor κB in rats. Neurol Sci (2012) 0.84
Hierarchical synthesis of Mo-Sn oxide cage-bell hybrid structures with superior lithium storage. Chem Commun (Camb) (2013) 0.84
A peripheral element assembles the compact core structure essential for group I intron self-splicing. Nucleic Acids Res (2005) 0.84
HSCARG inhibits activation of NF-kappaB by interacting with IkappaB kinase-beta. J Cell Sci (2009) 0.84
Therapeutic effects of topical doxycycline in a benzalkonium chloride-induced mouse dry eye model. Invest Ophthalmol Vis Sci (2014) 0.84
Effect of skill level on cardiorespiratory and metabolic responses during Tai Chi training. Eur J Sport Sci (2011) 0.83