Published in Biochemistry on April 19, 1977
Multiple modes of activation of latent human fibroblast collagenase: evidence for the role of a Cys73 active-site zinc complex in latency and a "cysteine switch" mechanism for activation. Proc Natl Acad Sci U S A (1990) 2.68
Neutral metalloproteinases produced by human mononuclear phagocytes. Enzyme profile, regulation, and expression during cellular development. J Clin Invest (1990) 2.56
Tissue cooperation in a proteolytic cascade activating human interstitial collagenase. Proc Natl Acad Sci U S A (1989) 2.26
Preferential digestion of basement membrane collagen by an enzyme derived from a metastatic murine tumor. Proc Natl Acad Sci U S A (1979) 2.25
Marfan syndrome: abnormal alpha 2 chain in type I collagen. Proc Natl Acad Sci U S A (1981) 1.78
Scleroderma: increased biosynthesis of triple-helical type I and type III procollagens associated with unaltered expression of collagenase by skin fibroblasts in culture. J Clin Invest (1979) 1.73
The interaction of purified rabbit bone collagenase with purified rabbit bone metalloproteinase inhibitor. Biochem J (1983) 1.72
Abnormal alpha 2-chain in type I collagen from a patient with a form of osteogenesis imperfecta. J Clin Invest (1983) 1.71
Stimulation of in vitro human skin collagenase expression by platelet-derived growth factor. Proc Natl Acad Sci U S A (1985) 1.65
Primary structure and cDNA cloning of human fibroblast collagenase inhibitor. Proc Natl Acad Sci U S A (1986) 1.63
Human alveolar macrophages produce a fibroblast-like collagenase and collagenase inhibitor. J Clin Invest (1985) 1.61
Purification of pig synovial collagenase to high specific activity. Biochem J (1979) 1.53
Collagenase production by rheumatoid synovial cells: morphological and immunohistochemical studies of the dendritic cell. Ann Rheum Dis (1979) 1.50
Isolated osteoclasts resorb the organic and inorganic components of bone. J Cell Biol (1986) 1.47
Human fibroblast collagenase: glycosylation and tissue-specific levels of enzyme synthesis. Proc Natl Acad Sci U S A (1986) 1.44
Purification, characterization and inhibition of human skin collagenase. Biochem J (1978) 1.35
Immune modulation of metalloproteinase production in human macrophages. Selective pretranslational suppression of interstitial collagenase and stromelysin biosynthesis by interferon-gamma. J Clin Invest (1990) 1.28
Biosynthesis and secretion of procollagenase by rabbit synovial fibroblasts. Inhibition of procollagenase secretion by monensin and evidence for glycosylation of procollagenase. Biochem J (1983) 1.21
Collagenase is a major gene product of induced rabbit synovial fibroblasts. J Cell Biol (1984) 1.20
Platelet-derived collagenase inhibitor: characterization and subcellular localization. Proc Natl Acad Sci U S A (1985) 1.15
Activation in vitro of rheumatoid synovial collagenase from cell cultures. J Clin Invest (1978) 1.14
Determination of interstitial collagenase (MMP-1) in patients with rheumatoid arthritis. Ann Rheum Dis (1995) 1.12
Recessive dystrophic epidermolysis bullosa: evidence for an altered collagenase in fibroblast cultures. Proc Natl Acad Sci U S A (1977) 1.07
Differentiation of a human leukemia cell line and expression of collagenase inhibitor. Proc Natl Acad Sci U S A (1985) 1.05
Complete degradation of type X collagen requires the combined action of interstitial collagenase and osteoclast-derived cathepsin-B. J Clin Invest (1995) 1.04
Heparin inhibits the induction of three matrix metalloproteinases (stromelysin, 92-kD gelatinase, and collagenase) in primate arterial smooth muscle cells. J Clin Invest (1994) 1.04
Heterogeneity among human collagenases demonstrated by monoclonal antibody that selectively recognizes and inhibits human neutrophil collagenase. J Exp Med (1984) 1.00
Interleukin 13 blocks the release of collagen from bovine nasal cartilage treated with proinflammatory cytokines. Ann Rheum Dis (2001) 0.99
Increased expression levels of integrin alphavbeta5 on scleroderma fibroblasts. Am J Pathol (2004) 0.98
Metalloproteinases and tissue inhibitor of metalloproteinases in mesothelial cells. Cellular differentiation influences expression. J Clin Invest (1993) 0.97
Properties of pig synovial collagenase. Biochem J (1980) 0.96
Human skin collagenase in recessive dystrophic epidermolysis bullosa. Purification of a mutant enzyme from fibroblast cultures. J Clin Invest (1982) 0.94
Autoregulation of collagenase production by a protein synthesized and secreted by synovial fibroblasts: cellular mechanism for control of collagen degradation. Proc Natl Acad Sci U S A (1985) 0.93
The fibrinolytic system in dissemination and matrix protein deposition during a mycobacterium infection. Am J Pathol (2003) 0.93
Thermal stability of human-fibroblast-collagenase-cleavage products of type-I and type-III collagens. Biochem J (1987) 0.91
Transforming growth factor alpha induces collagen degradation and cell migration in differentiating human epidermal raft cultures. Cell Regul (1991) 0.90
Pathology of collagen degradation. A review. Am J Pathol (1978) 0.89
Purification of a metalloproteinase inhibitor from human rheumatoid synovial fluid. Biochem J (1985) 0.88
Enhanced biosynthesis of human skin collagenase in fibroblast cultures from recessive dystrophic epidermolysis bullosa. J Clin Invest (1980) 0.87
Human osteoblasts in vitro secrete tissue inhibitor of metalloproteinases and gelatinase but not interstitial collagenase as major cellular products. J Clin Invest (1989) 0.86
Radioimmunoassay of soluble and insoluble collagenases in fibrotic liver. Biochem J (1984) 0.84
Regulation of connective tissue collagenase production: stimulators from adult and fetal epidermal cells. J Cell Biol (1984) 0.82
Correlation of collagenase secretion with metastatic-colonization potential in naturally occurring murine mammary tumours. Br J Cancer (1982) 0.82
Esculetin inhibits cartilage resorption induced by interleukin 1alpha in combination with oncostatin M. Ann Rheum Dis (2001) 0.80
Mycoplasma-induced BALB/c 3T3 collagenase is a mammalian enzyme. Biochem J (1983) 0.79
Collagen degradation in the pregnant human cervix at term and after prostaglandin-induced cervical ripening. Arch Gynecol (1987) 0.77
Collagenase activity in the cervix of non-pregnant and pregnant women. Arch Gynecol Obstet (1990) 0.75
Age-related thermal stability and susceptibility to proteolysis of rat bone collagen. Biochem J (1990) 0.75
SV40-transformed human lung fibroblasts secrete a 92-kDa type IV collagenase which is identical to that secreted by normal human macrophages. J Biol Chem (1989) 5.64
H-ras oncogene-transformed human bronchial epithelial cells (TBE-1) secrete a single metalloprotease capable of degrading basement membrane collagen. J Biol Chem (1988) 4.06
Human fibroblast collagenase. Complete primary structure and homology to an oncogene transformation-induced rat protein. J Biol Chem (1986) 3.67
Revised clinical and laboratory criteria for subtypes of inherited epidermolysis bullosa. A consensus report by the Subcommittee on Diagnosis and Classification of the National Epidermolysis Bullosa Registry. J Am Acad Dermatol (1991) 2.79
Neutral metalloproteinases produced by human mononuclear phagocytes. Enzyme profile, regulation, and expression during cellular development. J Clin Invest (1990) 2.56
Studies on collagenase from rheumatoid synovium in tissue culture. J Clin Invest (1968) 2.42
The collagen substrate specificity of human skin fibroblast collagenase. J Biol Chem (1981) 2.26
Tissue cooperation in a proteolytic cascade activating human interstitial collagenase. Proc Natl Acad Sci U S A (1989) 2.26
Human collagenase: identification and characterization of an enzyme from rheumatoid synovium in culture. Science (1967) 2.15
Vascular endothelial growth factor induces interstitial collagenase expression in human endothelial cells. J Cell Physiol (1992) 2.14
Human 72-kilodalton type IV collagenase forms a complex with a tissue inhibitor of metalloproteases designated TIMP-2. Proc Natl Acad Sci U S A (1989) 2.12
Collagenase production by human skin fibroblasts. Biochem Biophys Res Commun (1975) 2.12
Human skin collagenase. Isolation and mechanism of attack on the collagen molecule. Biochim Biophys Acta (1968) 2.05
Revised classification system for inherited epidermolysis bullosa: Report of the Second International Consensus Meeting on diagnosis and classification of epidermolysis bullosa. J Am Acad Dermatol (2000) 1.97
Comparison of nerve cell and nerve cell plus Schwann cell cultures, with particular emphasis on basal lamina and collagen formation. J Cell Biol (1980) 1.96
Human skin fibroblast collagenase inhibitor. Comparative studies in human connective tissues, serum, and amniotic fluid. J Biol Chem (1983) 1.89
Human skin fibroblast stromelysin: structure, glycosylation, substrate specificity, and differential expression in normal and tumorigenic cells. Proc Natl Acad Sci U S A (1987) 1.89
The activation of human skin fibroblast procollagenase. Sequence identification of the major conversion products. J Biol Chem (1987) 1.78
Scleroderma: increased biosynthesis of triple-helical type I and type III procollagens associated with unaltered expression of collagenase by skin fibroblasts in culture. J Clin Invest (1979) 1.73
Connective tissue nevi of the skin. Clinical, genetic, and histopathologic classification of hamartomas of the collagen, elastin, and proteoglycan type. J Am Acad Dermatol (1980) 1.71
Human type VII collagen: cDNA cloning and chromosomal mapping of the gene. Proc Natl Acad Sci U S A (1991) 1.66
Stimulation of in vitro human skin collagenase expression by platelet-derived growth factor. Proc Natl Acad Sci U S A (1985) 1.65
Integrin alpha 2 beta 1 (VLA-2) mediates reorganization and contraction of collagen matrices by human cells. Cell (1991) 1.65
Primary structure and cDNA cloning of human fibroblast collagenase inhibitor. Proc Natl Acad Sci U S A (1986) 1.63
Rat collagenase. Cloning, amino acid sequence comparison, and parathyroid hormone regulation in osteoblastic cells. J Biol Chem (1990) 1.63
Phenytoin therapy of recessive dystrophic epidermolysis bullosa. Clinical trial and proposed mechanism of action on collagenase. N Engl J Med (1980) 1.58
A program of cell death and extracellular matrix degradation is activated in the amnion before the onset of labor. J Clin Invest (1996) 1.57
Cutaneous mycobacteriosis: analysis of 34 cases with a new classification of the disease. Medicine (Baltimore) (1981) 1.57
Human skin collagenase: relationship to the pathogenesis of epidermolysis bullosa dystrophica. J Invest Dermatol (1969) 1.54
Inhibition of human skin collagenase by human serum. J Lab Clin Med (1970) 1.53
The collagen substrate specificity of human neutrophil collagenase. J Biol Chem (1987) 1.49
Human skin fibroblast collagenase inhibitor. Purification and biochemical characterization. J Biol Chem (1983) 1.49
Extracorporeal photopheresis for the treatment of cutaneous T-cell lymphoma. J Am Acad Dermatol (1992) 1.48
Isolated osteoclasts resorb the organic and inorganic components of bone. J Cell Biol (1986) 1.47
Human skin fibroblast collagenase: chemical properties of precursor and active forms. Biochemistry (1978) 1.47
Human fibroblast collagenase: glycosylation and tissue-specific levels of enzyme synthesis. Proc Natl Acad Sci U S A (1986) 1.44
The North American experience with photopheresis. Ther Apher (1999) 1.42
Human skin fibroblast procollagenase: mechanisms of activation by organomercurials and trypsin. Biochemistry (1983) 1.39
Enzyme-linked immunosorbent assay for human skin collagenase. Coll Relat Res (1983) 1.38
A specific inhibitor of vertebrate collagenase produced by human skin fibroblasts. J Biol Chem (1979) 1.37
Human skin fibroblast collagenase: interaction with substrate and inhibitor. Coll Relat Res (1985) 1.37
Collagenase-3 binds to a specific receptor and requires the low density lipoprotein receptor-related protein for internalization. J Biol Chem (1999) 1.36
Quantitation and immunocytochemical localization of human skin collagenase in basal cell carcinoma. J Invest Dermatol (1977) 1.33
Human skin collagenase. The role of serum alpha-globulins in the control of activity in vivo and in vitro. Proc Natl Acad Sci U S A (1971) 1.31
Collagenase from rat uterus. Isolation and partial characterization. Biochemistry (1970) 1.30
Human skin collagenase: localization and distribution in normal human skin. J Invest Dermatol (1969) 1.28
Differential susceptibility of type X collagen to cleavage by two mammalian interstitial collagenases and 72-kDa type IV collagenase. J Biol Chem (1990) 1.28
Premature termination codons in the type VII collagen gene (COL7A1) underlie severe, mutilating recessive dystrophic epidermolysis bullosa. Genomics (1994) 1.28
Guidelines for clinical trials in systemic sclerosis (scleroderma). I. Disease-modifying interventions. The American College of Rheumatology Committee on Design and Outcomes in Clinical Trials in Systemic Sclerosis. Arthritis Rheum (1995) 1.28
Interstitial collagenase (matrix metalloproteinase-1) expresses serpinase activity. J Clin Invest (1991) 1.25
The assembly of laminin-5 subunits. J Biol Chem (1995) 1.24
Different collagenase gene products have different roles in degradation of type I collagen. J Biol Chem (1996) 1.23
Manganese superoxide dismutase signals matrix metalloproteinase expression via H2O2-dependent ERK1/2 activation. J Biol Chem (2001) 1.23
EGF and TGF alpha influence in vitro lung development by the induction of matrix-degrading metalloproteinases. Int J Dev Biol (1991) 1.22
Type X collagen contains two cleavage sites for a vertebrate collagenase. J Biol Chem (1986) 1.22
Initiation of osteoclast bone resorption by interstitial collagenase. J Biol Chem (1997) 1.21
Melanoma growth-stimulatory activity/GRO decreases collagen expression by human fibroblasts. Regulation by C-X-C but not C-C cytokines. J Biol Chem (1993) 1.21
Growth stimulation of human keratinocytes by tissue inhibitor of metalloproteinases. J Invest Dermatol (1991) 1.21
The collagen substrate specificity of rat uterus collagenase. J Biol Chem (1983) 1.20
Recessive dystrophic epidermolysis bullosa phenotype is preserved in xenografts using SCID mice: development of an experimental in vivo model. J Invest Dermatol (1992) 1.20
Human skin fibroblast collagenase. Assessment of activation energy and deuterium isotope effect with collagenous substrates. J Biol Chem (1981) 1.17
Platelet-derived collagenase inhibitor: characterization and subcellular localization. Proc Natl Acad Sci U S A (1985) 1.15
Purification and properties of a gelatin-specific neutral protease from human skin. J Biol Chem (1981) 1.15
Purification and properties of rat uterine procollagenase. Arch Biochem Biophys (1983) 1.15
The function of Ca+ in the action of mammalian collagenases. Arch Biochem Biophys (1976) 1.13
Isotretinoin treatment of Darier's disease. J Am Acad Dermatol (1982) 1.13
The gelatinolytic activity of rat uterus collagenase. J Biol Chem (1985) 1.13
Role of matrix metalloproteinases in failure to re-epithelialize after corneal injury. Am J Pathol (1996) 1.13
Animal and human collagenases. J Invest Dermatol (1970) 1.12
The gelatinolytic activity of human skin fibroblast collagenase. J Biol Chem (1982) 1.12