| Rank |
Title |
Journal |
Year |
PubWeight™‹?› |
|
1
|
Association analyses of 249,796 individuals reveal 18 new loci associated with body mass index.
|
Nat Genet
|
2010
|
23.08
|
|
2
|
Hundreds of variants clustered in genomic loci and biological pathways affect human height.
|
Nature
|
2010
|
20.01
|
|
3
|
New genetic loci implicated in fasting glucose homeostasis and their impact on type 2 diabetes risk.
|
Nat Genet
|
2010
|
17.89
|
|
4
|
Variation in FTO contributes to childhood obesity and severe adult obesity.
|
Nat Genet
|
2007
|
13.62
|
|
5
|
Meta-analysis identifies 13 new loci associated with waist-hip ratio and reveals sexual dimorphism in the genetic basis of fat distribution.
|
Nat Genet
|
2010
|
7.94
|
|
6
|
Genetic variation in GIPR influences the glucose and insulin responses to an oral glucose challenge.
|
Nat Genet
|
2010
|
6.66
|
|
7
|
Sequence variants at CHRNB3-CHRNA6 and CYP2A6 affect smoking behavior.
|
Nat Genet
|
2010
|
6.49
|
|
8
|
Genome-wide association study for early-onset and morbid adult obesity identifies three new risk loci in European populations.
|
Nat Genet
|
2009
|
6.39
|
|
9
|
New loci associated with kidney function and chronic kidney disease.
|
Nat Genet
|
2010
|
5.58
|
|
10
|
Large-scale association analyses identify new loci influencing glycemic traits and provide insight into the underlying biological pathways.
|
Nat Genet
|
2012
|
4.73
|
|
11
|
A genome-wide approach accounting for body mass index identifies genetic variants influencing fasting glycemic traits and insulin resistance.
|
Nat Genet
|
2012
|
4.37
|
|
12
|
Common variants at 10 genomic loci influence hemoglobin A₁(C) levels via glycemic and nonglycemic pathways.
|
Diabetes
|
2010
|
4.07
|
|
13
|
68Ga-DOTA-Tyr3-octreotide PET in neuroendocrine tumors: comparison with somatostatin receptor scintigraphy and CT.
|
J Nucl Med
|
2007
|
3.98
|
|
14
|
Insulin-sensitive obesity.
|
Am J Physiol Endocrinol Metab
|
2010
|
3.46
|
|
15
|
Common nonsynonymous variants in PCSK1 confer risk of obesity.
|
Nat Genet
|
2008
|
3.24
|
|
16
|
Novel loci for adiponectin levels and their influence on type 2 diabetes and metabolic traits: a multi-ethnic meta-analysis of 45,891 individuals.
|
PLoS Genet
|
2012
|
3.21
|
|
17
|
Two new Loci for body-weight regulation identified in a joint analysis of genome-wide association studies for early-onset extreme obesity in French and german study groups.
|
PLoS Genet
|
2010
|
3.21
|
|
18
|
New gene functions in megakaryopoiesis and platelet formation.
|
Nature
|
2011
|
3.14
|
|
19
|
Sex-stratified genome-wide association studies including 270,000 individuals show sexual dimorphism in genetic loci for anthropometric traits.
|
PLoS Genet
|
2013
|
2.83
|
|
20
|
Serum retinol-binding protein is more highly expressed in visceral than in subcutaneous adipose tissue and is a marker of intra-abdominal fat mass.
|
Cell Metab
|
2007
|
2.69
|
|
21
|
Chymotrypsin C (CTRC) variants that diminish activity or secretion are associated with chronic pancreatitis.
|
Nat Genet
|
2007
|
2.48
|
|
22
|
Detailed physiologic characterization reveals diverse mechanisms for novel genetic Loci regulating glucose and insulin metabolism in humans.
|
Diabetes
|
2010
|
2.44
|
|
23
|
Plasma visfatin concentrations and fat depot-specific mRNA expression in humans.
|
Diabetes
|
2005
|
2.34
|
|
24
|
Variants in CPA1 are strongly associated with early onset chronic pancreatitis.
|
Nat Genet
|
2013
|
2.10
|
|
25
|
Serum levels of the adipokine progranulin depend on renal function.
|
Diabetes Care
|
2012
|
2.03
|
|
26
|
MicroRNA expression in human omental and subcutaneous adipose tissue.
|
PLoS One
|
2009
|
1.81
|
|
27
|
CFTR, SPINK1, CTRC and PRSS1 variants in chronic pancreatitis: is the role of mutated CFTR overestimated?
|
Gut
|
2012
|
1.77
|
|
28
|
A genome-wide association search for type 2 diabetes genes in African Americans.
|
PLoS One
|
2012
|
1.72
|
|
29
|
ENPP1 variants and haplotypes predispose to early onset obesity and impaired glucose and insulin metabolism in German obese children.
|
J Clin Endocrinol Metab
|
2006
|
1.71
|
|
30
|
Genome-wide association and functional follow-up reveals new loci for kidney function.
|
PLoS Genet
|
2012
|
1.68
|
|
31
|
Image fusion analysis of 99m Tc-HYNIC-octreotide scintigraphy and CT/MRI in patients with thyroid-associated orbitopathy: the importance of the lacrimal gland.
|
Eur J Nucl Med Mol Imaging
|
2003
|
1.45
|
|
32
|
Gastric bypass surgery alters behavioral and neural taste functions for sweet taste in obese rats.
|
Am J Physiol Gastrointest Liver Physiol
|
2010
|
1.36
|
|
33
|
Lipoatrophy associated with the use of insulin analogues: a new case associated with the use of insulin glargine and review of the literature.
|
Expert Opin Drug Saf
|
2010
|
1.33
|
|
34
|
Vaspin gene expression in human adipose tissue: association with obesity and type 2 diabetes.
|
Biochem Biophys Res Commun
|
2005
|
1.30
|
|
35
|
Association of FTO variants with BMI and fat mass in the self-contained population of Sorbs in Germany.
|
Eur J Hum Genet
|
2010
|
1.26
|
|
36
|
Grape seed proanthocyanidins improved cardiac recovery during reperfusion after ischemia in isolated rat hearts.
|
Am J Clin Nutr
|
2002
|
1.26
|
|
37
|
Combined proteomic and metabolomic profiling of serum reveals association of the complement system with obesity and identifies novel markers of body fat mass changes.
|
J Proteome Res
|
2011
|
1.20
|
|
38
|
Genetic variation in GPR133 is associated with height: genome wide association study in the self-contained population of Sorbs.
|
Hum Mol Genet
|
2009
|
1.16
|
|
39
|
Genetic variation in the Sorbs of eastern Germany in the context of broader European genetic diversity.
|
Eur J Hum Genet
|
2011
|
1.15
|
|
40
|
Ultrasound-guided lumbar facet nerve block: accuracy of a new technique confirmed by computed tomography.
|
Anesthesiology
|
2004
|
1.14
|
|
41
|
Integration of genome-wide association studies with biological knowledge identifies six novel genes related to kidney function.
|
Hum Mol Genet
|
2012
|
1.14
|
|
42
|
Long-term exercise training decreases interleukin-6 (IL-6) serum levels in subjects with impaired glucose tolerance: effect of the -174G/C variant in IL-6 gene.
|
Eur J Endocrinol
|
2008
|
1.11
|
|
43
|
Adipose tissue expression and genetic variants of the bone morphogenetic protein receptor 1A gene (BMPR1A) are associated with human obesity.
|
Diabetes
|
2009
|
1.11
|
|
44
|
Frameless stereotactic cannulation of the foramen ovale for ablative treatment of trigeminal neuralgia.
|
Neurosurgery
|
2006
|
1.11
|
|
45
|
68Ga-DOTA-Tyr3-octreotide PET for assessing response to somatostatin-receptor-mediated radionuclide therapy.
|
J Nucl Med
|
2009
|
1.10
|
|
46
|
Vaspin serum concentrations in patients with carotid stenosis.
|
Atherosclerosis
|
2008
|
1.08
|
|
47
|
Heme oxygenase-1-related carbon monoxide production and ventricular fibrillation in isolated ischemic/reperfused mouse myocardium.
|
FASEB J
|
2003
|
1.08
|
|
48
|
Genomic insights into the origin of farming in the ancient Near East.
|
Nature
|
2016
|
1.07
|
|
49
|
Palmitate induced IL-6 and MCP-1 expression in human bladder smooth muscle cells provides a link between diabetes and urinary tract infections.
|
PLoS One
|
2010
|
1.06
|
|
50
|
TCF7L2 gene polymorphisms confer an increased risk for early impairment of glucose metabolism and increased height in obese children.
|
J Clin Endocrinol Metab
|
2007
|
1.04
|
|
51
|
Sequence variants at CYP1A1-CYP1A2 and AHR associate with coffee consumption.
|
Hum Mol Genet
|
2011
|
1.03
|
|
52
|
Genetic variation in the visfatin gene (PBEF1) and its relation to glucose metabolism and fat-depot-specific messenger ribonucleic acid expression in humans.
|
J Clin Endocrinol Metab
|
2006
|
1.01
|
|
53
|
Ultrasonographic appearance of supinator syndrome.
|
J Ultrasound Med
|
2002
|
1.01
|
|
54
|
The genetics of fat distribution.
|
Diabetologia
|
2014
|
0.99
|
|
55
|
Targeted SNP genotyping using the TaqMan® assay.
|
Methods Mol Biol
|
2011
|
0.97
|
|
56
|
High-resolution sonography of lower extremity peripheral nerves: anatomic correlation and spectrum of disease.
|
J Ultrasound Med
|
2002
|
0.97
|
|
57
|
Genetics of adiponectin.
|
Biochimie
|
2012
|
0.96
|
|
58
|
Substantial increase in incidence of severe hypoglycemia between 1997-2000 and 2007-2010: a German longitudinal population-based study.
|
Diabetes Care
|
2012
|
0.96
|
|
59
|
Sonographically guided phenol injection in painful stump neuroma.
|
AJR Am J Roentgenol
|
2004
|
0.95
|
|
60
|
Parabrachial coding of sapid sucrose: relevance to reward and obesity.
|
Ann N Y Acad Sci
|
2009
|
0.94
|
|
61
|
Image fusion analysis of (99m)Tc-HYNIC-Tyr(3)-octreotide SPECT and diagnostic CT using an immobilisation device with external markers in patients with endocrine tumours.
|
Eur J Nucl Med Mol Imaging
|
2005
|
0.94
|
|
62
|
TCF7L2 and therapeutic response to sulfonylureas in patients with type 2 diabetes.
|
BMC Med Genet
|
2011
|
0.94
|
|
63
|
Polygenic contribution to obesity: genome-wide strategies reveal new targets.
|
Front Horm Res
|
2008
|
0.93
|
|
64
|
TAS2R38 and its influence on smoking behavior and glucose homeostasis in the German Sorbs.
|
PLoS One
|
2013
|
0.93
|
|
65
|
The rectogenital septum: morphology, function, and clinical relevance.
|
Dis Colon Rectum
|
2004
|
0.93
|
|
66
|
Virtual neck exploration: a new method for localizing abnormal parathyroid glands.
|
Ann Surg
|
2009
|
0.92
|
|
67
|
Ultrasonography of the accessory nerve: normal and pathologic findings in cadavers and patients with iatrogenic accessory nerve palsy.
|
J Ultrasound Med
|
2002
|
0.91
|
|
68
|
Population-genetic comparison of the Sorbian isolate population in Germany with the German KORA population using genome-wide SNP arrays.
|
BMC Genet
|
2011
|
0.91
|
|
69
|
Lack of association between the tagging SNP A+930-->G of SOCS3 and type 2 diabetes mellitus: meta-analysis of four independent study populations.
|
PLoS One
|
2008
|
0.91
|
|
70
|
Evaluation of A2BP1 as an obesity gene.
|
Diabetes
|
2010
|
0.91
|
|
71
|
Genome-wide association study identifies two novel regions at 11p15.5-p13 and 1p31 with major impact on acute-phase serum amyloid A.
|
PLoS Genet
|
2010
|
0.91
|
|
72
|
Genetic and evolutionary analyses of the human bone morphogenetic protein receptor 2 (BMPR2) in the pathophysiology of obesity.
|
PLoS One
|
2011
|
0.90
|
|
73
|
Common genetic variation near MC4R has a sex-specific impact on human brain structure and eating behavior.
|
PLoS One
|
2013
|
0.90
|
|
74
|
Contemporary paternal genetic landscape of Polish and German populations: from early medieval Slavic expansion to post-World War II resettlements.
|
Eur J Hum Genet
|
2012
|
0.90
|
|
75
|
A critical appraisal of time-lapse imaging for embryo selection: where are we and where do we need to go?
|
J Assist Reprod Genet
|
2015
|
0.89
|
|
76
|
Postthaw blastomere survival is predictive of the success of frozen-thawed embryo transfer cycles.
|
Fertil Steril
|
2004
|
0.89
|
|
77
|
Severe sulfonylurea-induced hypoglycemia: a problem of uncritical prescription and deficiencies of diabetes care in geriatric patients.
|
Expert Opin Drug Saf
|
2010
|
0.89
|
|
78
|
CT-MIBI image fusion: a new preoperative localization technique for primary, recurrent, and persistent hyperparathyroidism.
|
Surgery
|
2004
|
0.89
|
|
79
|
Effects of genetic variation in the visfatin gene (PBEF1) on obesity, glucose metabolism, and blood pressure in children.
|
Metabolism
|
2007
|
0.88
|
|
80
|
Follicular and luteal phase endometrial thickness and echogenic pattern and pregnancy outcome in oocyte donation cycles.
|
J Assist Reprod Genet
|
2009
|
0.88
|
|
81
|
Effects of genetic variants in ADCY5, GIPR, GCKR and VPS13C on early impairment of glucose and insulin metabolism in children.
|
PLoS One
|
2011
|
0.86
|
|
82
|
Role of genetic variation in the cannabinoid type 1 receptor gene (CNR1) in the pathophysiology of human obesity.
|
Pharmacogenomics
|
2010
|
0.86
|
|
83
|
Stereotactic CT-guided percutaneous stabilization of posterior pelvic ring fractures: a preclinical cadaver study.
|
J Vasc Interv Radiol
|
2008
|
0.86
|
|
84
|
No interactions between previously associated 2-hour glucose gene variants and physical activity or BMI on 2-hour glucose levels.
|
Diabetes
|
2012
|
0.86
|
|
85
|
The ultrasonographic appearance of the femoral nerve and cases of iatrogenic impairment.
|
J Ultrasound Med
|
2003
|
0.85
|
|
86
|
Mitochondrial gene expression and ventricular fibrillation in ischemic/reperfused nondiabetic and diabetic myocardium.
|
Biochem Pharmacol
|
2002
|
0.85
|
|
87
|
Impact of clinical factors and CYP2C9 variants for the risk of severe sulfonylurea-induced hypoglycemia.
|
Eur J Clin Pharmacol
|
2011
|
0.85
|
|
88
|
The administration of alpha-melanocyte-stimulating hormone protects the ischemic/reperfused myocardium.
|
Eur J Pharmacol
|
2003
|
0.85
|
|
89
|
Vaspin inhibits kallikrein 7 by serpin mechanism.
|
Cell Mol Life Sci
|
2013
|
0.84
|
|
90
|
Metabolic effects of the Gly1057Asp polymorphism in IRS-2 and interactions with obesity.
|
Diabetes
|
2003
|
0.83
|
|
91
|
Preliminary report: circulating levels of the adipokine vaspin in gestational diabetes mellitus and preeclampsia.
|
Metabolism
|
2009
|
0.83
|
|
92
|
Congenital pseudarthrosis of the clavicle causing thoracic outlet syndrome.
|
BMJ Case Rep
|
2013
|
0.83
|
|
93
|
R1467H variant in the rho guanine nucleotide exchange factor 11 (ARHGEF11) is associated with impaired glucose tolerance and type 2 diabetes in German Caucasians.
|
J Hum Genet
|
2008
|
0.83
|
|
94
|
Pathologic-sonographic correlation in temporomandibular joint pathology.
|
Eur Radiol
|
2006
|
0.83
|
|
95
|
Direct coaptation of extensive facial nerve defects after removal of the superficial part of the parotid gland: an anatomic study.
|
Head Neck
|
2002
|
0.82
|
|
96
|
Fibroblast growth factor-21 serum concentrations are associated with metabolic and hepatic markers in humans.
|
J Endocrinol
|
2013
|
0.82
|
|
97
|
Genetic and biochemical evidence for a functional role of BACE1 in the regulation of insulin mRNA expression.
|
Obesity (Silver Spring)
|
2013
|
0.82
|
|
98
|
Common variants in Mendelian kidney disease genes and their association with renal function.
|
J Am Soc Nephrol
|
2013
|
0.82
|
|
99
|
Global DNA methylation levels in human adipose tissue are related to fat distribution and glucose homeostasis.
|
Diabetologia
|
2014
|
0.82
|
|
100
|
Role of vaspin in human eating behaviour.
|
PLoS One
|
2013
|
0.81
|
|
101
|
CT-MIBI-SPECT image fusion predicts multiglandular disease in hyperparathyroidism.
|
Langenbecks Arch Surg
|
2009
|
0.81
|
|
102
|
C57BL/6JRj mice are protected against diet induced obesity (DIO).
|
Biochem Biophys Res Commun
|
2011
|
0.81
|
|
103
|
Serum vaspin concentrations are decreased after exercise-induced oxidative stress.
|
Obes Facts
|
2010
|
0.81
|
|
104
|
Repin1 maybe involved in the regulation of cell size and glucose transport in adipocytes.
|
Biochem Biophys Res Commun
|
2010
|
0.81
|
|
105
|
An ACACB variant implicated in diabetic nephropathy associates with body mass index and gene expression in obese subjects.
|
PLoS One
|
2013
|
0.80
|
|
106
|
Nicotinamide nucleotide transhydrogenase mRNA expression is related to human obesity.
|
Obesity (Silver Spring)
|
2013
|
0.80
|
|
107
|
Adipose tissue depot specific promoter methylation of TMEM18.
|
J Mol Med (Berl)
|
2014
|
0.80
|
|
108
|
The effect of ACACB cis-variants on gene expression and metabolic traits.
|
PLoS One
|
2011
|
0.79
|
|
109
|
A common variant of PNPLA3 (p.I148M) is not associated with alcoholic chronic pancreatitis.
|
PLoS One
|
2012
|
0.79
|
|
110
|
Cyclic GMP-mediated activation of a glibenclamide-sensitive mechanism in the rabbit sphincter of Oddi.
|
Dig Dis Sci
|
2004
|
0.79
|
|
111
|
Complete analysis of the human mesotrypsinogen gene (PRSS3) in patients with chronic pancreatitis.
|
Pancreatology
|
2010
|
0.78
|
|
112
|
Role of genetic variants in ADIPOQ in human eating behavior.
|
Genes Nutr
|
2014
|
0.78
|
|
113
|
CYP2C metabolism of oral antidiabetic drugs--impact on pharmacokinetics, drug interactions and pharmacogenetic aspects.
|
Expert Opin Drug Metab Toxicol
|
2012
|
0.78
|
|
114
|
Effect of genetic variation in the human fatty acid synthase gene (FASN) on obesity and fat depot-specific mRNA expression.
|
Obesity (Silver Spring)
|
2009
|
0.78
|
|
115
|
Genetic analyses of heme oxygenase 1 (HMOX1) in different forms of pancreatitis.
|
PLoS One
|
2012
|
0.78
|
|
116
|
Mutational analysis of the gene encoding the zymogen granule membrane glycoprotein 2 (GP2) in patients with chronic pancreatitis.
|
Pancreas
|
2010
|
0.77
|
|
117
|
THOC5: a novel gene involved in HDL-cholesterol metabolism.
|
J Lipid Res
|
2013
|
0.77
|
|
118
|
Novel heterozygous IGF1R mutation in two brothers with developing impaired glucose tolerance.
|
J Pediatr Endocrinol Metab
|
2015
|
0.77
|
|
119
|
Positional cloning of an obesity/diabetes susceptibility gene(s) on chromosome 11 in Pima Indians.
|
Ann N Y Acad Sci
|
2002
|
0.77
|
|
120
|
Role of genetic variation in the human sodium-glucose cotransporter 2 gene (SGLT2) in glucose homeostasis.
|
Pharmacogenomics
|
2011
|
0.77
|
|
121
|
Reduced food intake and body weight in mice deficient for the G protein-coupled receptor GPR82.
|
PLoS One
|
2011
|
0.77
|
|
122
|
Rapid response to and long-term effectiveness of anti-CD20 antibody in conventional therapy resistant Graves' orbitopathy: A five-year follow-up study.
|
Autoimmunity
|
2014
|
0.76
|
|
123
|
SGLT2: a potential target for the pharmacogenetics of Type 2 diabetes?
|
Pharmacogenomics
|
2013
|
0.76
|
|
124
|
Effects of SLC10A2 variant rs9514089 on gallstone risk and serum cholesterol levels- meta-analysis of three independent cohorts.
|
BMC Med Genet
|
2011
|
0.76
|
|
125
|
Phenotype of a patient with a de novo mutation in the hepatocyte nuclear factor 1beta/maturity-onset diabetes of the young type 5 gene.
|
Metabolism
|
2008
|
0.76
|
|
126
|
Noninvasive characterization of graft steatosis after liver transplantation.
|
Scand J Gastroenterol
|
2014
|
0.76
|
|
127
|
Blastocyst embryo transfer is the primary determinant for improved outcomes in oocyte donation cycles.
|
J Obstet Gynaecol Res
|
2010
|
0.76
|
|
128
|
Fat mass and obesity-associated (fto) gene and alcohol intake.
|
Addiction
|
2012
|
0.76
|
|
129
|
Sequence analysis of the human tyrosylprotein sulfotransferase-2 gene in subjects with chronic pancreatitis.
|
Pancreatology
|
2010
|
0.76
|
|
130
|
Analysis of a rare functional truncating mutation rs61757459 in vaspin (SERPINA12) on circulating vaspin levels.
|
J Mol Med (Berl)
|
2013
|
0.75
|
|
131
|
Antral follice counts (AFC) predict ovarian response and pregnancy outcomes in oocyte donation cycles.
|
J Assist Reprod Genet
|
2010
|
0.75
|
|
132
|
Involvement of the chemokine-like receptor GPR33 in innate immunity.
|
Biochem Biophys Res Commun
|
2010
|
0.75
|
|
133
|
The Ser1369Ala variant of ABCC8 and the risk for severe sulfonylurea-induced hypoglycemia in German patients with Type 2 diabetes.
|
Pharmacogenomics
|
2012
|
0.75
|
|
134
|
Genetic analyses of bone morphogenetic protein 2, 4 and 7 in congenital combined pituitary hormone deficiency.
|
BMC Endocr Disord
|
2013
|
0.75
|
|
135
|
[Do epigenetic factors have an influence on body weight? The era of epigenome-association-studies in adipositas research has begun].
|
Dtsch Med Wochenschr
|
2014
|
0.75
|
|
136
|
Hepatic insulin sensitizing substance: a novel 'sensocrine' mechanism to increase insulin sensitivity in anaesthetized rats.
|
Br J Pharmacol
|
2003
|
0.75
|
|
137
|
Congenic BB.SHR (D4Mit6-Npy-Spr) rats: a new aid to dissect the genetics of obesity.
|
Obes Res
|
2002
|
0.75
|
|
138
|
Virtual neck exploration in patients with hyperparathyroidism and former cervical operations.
|
Langenbecks Arch Surg
|
2008
|
0.75
|
|
139
|
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