Published in Cancer Res on March 10, 2009
Unleashing formins to remodel the actin and microtubule cytoskeletons. Nat Rev Mol Cell Biol (2009) 3.45
Actin, microtubules, and vimentin intermediate filaments cooperate for elongation of invadopodia. J Cell Biol (2010) 2.62
A novel spatiotemporal RhoC activation pathway locally regulates cofilin activity at invadopodia. Curr Biol (2011) 2.34
The actin-bundling protein fascin stabilizes actin in invadopodia and potentiates protrusive invasion. Curr Biol (2010) 2.23
Actin machinery and mechanosensitivity in invadopodia, podosomes and focal adhesions. J Cell Sci (2009) 2.13
Contractility of the cell rear drives invasion of breast tumor cells in 3D Matrigel. Proc Natl Acad Sci U S A (2011) 1.98
LIM kinases are required for invasive path generation by tumor and tumor-associated stromal cells. J Cell Biol (2010) 1.79
Endophilin-A2 functions in membrane scission in clathrin-independent endocytosis. Nature (2014) 1.51
CDC42-interacting protein 4 promotes metastasis of nasopharyngeal carcinoma by mediating invadopodia formation and activating EGFR signaling. J Exp Clin Cancer Res (2017) 1.44
Establishment and validation of computational model for MT1-MMP dependent ECM degradation and intervention strategies. PLoS Comput Biol (2012) 1.33
Endosomal WASH and exocyst complexes control exocytosis of MT1-MMP at invadopodia. J Cell Biol (2013) 1.28
Adhesion rings surround invadopodia and promote maturation. Biol Open (2012) 1.23
Three-dimensional migration of macrophages requires Hck for podosome organization and extracellular matrix proteolysis. Blood (2009) 1.18
Signaling inputs to invadopodia and podosomes. J Cell Sci (2013) 1.18
The regulation of MMP targeting to invadopodia during cancer metastasis. Front Cell Dev Biol (2015) 1.11
Cells assemble invadopodia-like structures and invade into matrigel in a matrix metalloprotease dependent manner in the circular invasion assay. PLoS One (2012) 1.08
mDia1 and WAVE2 proteins interact directly with IRSp53 in filopodia and are involved in filopodium formation. J Biol Chem (2011) 1.06
CellGeo: a computational platform for the analysis of shape changes in cells with complex geometries. J Cell Biol (2014) 1.04
Dynamic remodeling of the actin cytoskeleton by FMNL1γ is required for structural maintenance of the Golgi complex. J Cell Sci (2011) 1.02
Physiological type I collagen organization induces the formation of a novel class of linear invadosomes. Mol Biol Cell (2011) 1.01
DIAPH3 governs the cellular transition to the amoeboid tumour phenotype. EMBO Mol Med (2012) 1.01
Rif-mDia1 interaction is involved in filopodium formation independent of Cdc42 and Rac effectors. J Biol Chem (2011) 1.00
Digging a little deeper: the stages of invadopodium formation and maturation. Eur J Cell Biol (2014) 1.00
ARF6-JIP3/4 regulate endosomal tubules for MT1-MMP exocytosis in cancer invasion. J Cell Biol (2015) 0.98
Integrin-matrix clusters form podosome-like adhesions in the absence of traction forces. Cell Rep (2013) 0.98
Cdc42 and Tks5: a minimal and universal molecular signature for functional invadosomes. Cell Adh Migr (2014) 0.95
Nck1 and Grb2 localization patterns can distinguish invadopodia from podosomes. Eur J Cell Biol (2010) 0.95
Invasive cells in animals and plants: searching for LECA machineries in later eukaryotic life. Biol Direct (2013) 0.92
Control of MT1-MMP transport by atypical PKC during breast-cancer progression. Proc Natl Acad Sci U S A (2014) 0.91
Importance of RhoGTPases in formation, characteristics, and functions of invadosomes. Small GTPases (2014) 0.90
Mechanical interplay between invadopodia and the nucleus in cultured cancer cells. Sci Rep (2015) 0.89
LIMK Regulates Tumor-Cell Invasion and Matrix Degradation Through Tyrosine Phosphorylation of MT1-MMP. Sci Rep (2016) 0.88
Roles of rho GTPases in intracellular transport and cellular transformation. Int J Mol Sci (2013) 0.88
mDia1-3 in mammalian filopodia. Commun Integr Biol (2012) 0.85
HDAC6 deacetylase activity is required for hypoxia-induced invadopodia formation and cell invasion. PLoS One (2013) 0.84
The interplay between the proteolytic, invasive, and adhesive domains of invadopodia and their roles in cancer invasion. Cell Adh Migr (2014) 0.83
Dia-interacting protein (DIP) imposes migratory plasticity in mDia2-dependent tumor cells in three-dimensional matrices. PLoS One (2012) 0.82
Cell polarity signaling in the plasticity of cancer cell invasiveness. Oncotarget (2016) 0.82
An mDia2/ROCK signaling axis regulates invasive egress from epithelial ovarian cancer spheroids. PLoS One (2014) 0.81
Inhibition of breast cancer invasion by TIS21(/BTG2/Pc3)-Akt1-Sp1-Nox4 pathway targeting actin nucleators, mDia genes. Oncogene (2015) 0.79
Fertility and polarized cell growth depends on eIF5A for translation of polyproline-rich formins in Saccharomyces cerevisiae. Genetics (2014) 0.79
Palladin regulation of the actin structures needed for cancer invasion. Cell Adh Migr (2013) 0.79
The Formin Diaphanous Regulates Myoblast Fusion through Actin Polymerization and Arp2/3 Regulation. PLoS Genet (2015) 0.78
Drosophila homologue of Diaphanous 1 (DIAPH1) controls the metastatic potential of colon cancer cells by regulating microtubule-dependent adhesion. Oncotarget (2015) 0.78
ARF6 promotes the formation of Rac1 and WAVE-dependent ventral F-actin rosettes in breast cancer cells in response to epidermal growth factor. PLoS One (2015) 0.77
RAB2A controls MT1-MMP endocytic and E-cadherin polarized Golgi trafficking to promote invasive breast cancer programs. EMBO Rep (2016) 0.77
Development and validation of a comprehensive genomic diagnostic tool for myeloid malignancies. Blood (2016) 0.76
Proteomic analyses uncover a new function and mode of action for mouse homolog of Diaphanous 2 (mDia2). Mol Cell Proteomics (2015) 0.76
A three-dimensional collagen construct to model lipopolysaccharide-induced activation of BV2 microglia. J Neuroinflammation (2014) 0.76
mDia1 regulates breast cancer invasion by controlling membrane type 1-matrix metalloproteinase localization. Oncotarget (2016) 0.76
The role of Tks adaptor proteins in invadopodia formation, growth and metastasis of melanoma. Oncotarget (2016) 0.75
Phase 1/2 study of rilotumumab (AMG 102), a hepatocyte growth factor inhibitor, and erlotinib in patients with advanced non-small cell lung cancer. Cancer (2017) 0.75
Isolation and characterization of exosomes from cell culture supernatants and biological fluids. Curr Protoc Cell Biol (2006) 13.29
ARF proteins: roles in membrane traffic and beyond. Nat Rev Mol Cell Biol (2006) 7.75
Exosomes--vesicular carriers for intercellular communication. Curr Opin Cell Biol (2009) 6.96
Exosomal-like vesicles are present in human blood plasma. Int Immunol (2005) 6.04
Exosomes: a common pathway for a specialized function. J Biochem (2006) 5.79
Exosomes: endosomal-derived vesicles shipping extracellular messages. Curr Opin Cell Biol (2004) 5.71
Rab27a and Rab27b control different steps of the exosome secretion pathway. Nat Cell Biol (2009) 5.44
NOX2 controls phagosomal pH to regulate antigen processing during crosspresentation by dendritic cells. Cell (2006) 5.35
Cells release prions in association with exosomes. Proc Natl Acad Sci U S A (2004) 5.17
Force mapping in epithelial cell migration. Proc Natl Acad Sci U S A (2005) 5.08
Munc13-4 is essential for cytolytic granules fusion and is mutated in a form of familial hemophagocytic lymphohistiocytosis (FHL3). Cell (2003) 4.94
The biogenesis and functions of exosomes. Traffic (2002) 4.49
Protein interaction mapping: a Drosophila case study. Genome Res (2005) 4.15
Biogenesis, secretion, and intercellular interactions of exosomes and other extracellular vesicles. Annu Rev Cell Dev Biol (2014) 3.97
Cells respond to mechanical stress by rapid disassembly of caveolae. Cell (2011) 3.55
Shiga toxin induces tubular membrane invaginations for its uptake into cells. Nature (2007) 3.51
Exosome secretion: molecular mechanisms and roles in immune responses. Traffic (2011) 3.36
TCR activation of human T cells induces the production of exosomes bearing the TCR/CD3/zeta complex. J Immunol (2002) 3.28
A novel dendritic cell subset involved in tumor immunosurveillance. Nat Med (2006) 3.21
As we wait: coping with an imperfect nomenclature for extracellular vesicles. J Extracell Vesicles (2013) 3.01
Matrix invasion by tumour cells: a focus on MT1-MMP trafficking to invadopodia. J Cell Sci (2009) 2.94
Assembly and role of pili in group B streptococci. Mol Microbiol (2006) 2.92
Genome Alteration Print (GAP): a tool to visualize and mine complex cancer genomic profiles obtained by SNP arrays. Genome Biol (2009) 2.88
Regulation of dendritic cell migration by CD74, the MHC class II-associated invariant chain. Science (2008) 2.88
ARF6-regulated shedding of tumor cell-derived plasma membrane microvesicles. Curr Biol (2009) 2.82
Rab38 and Rab32 control post-Golgi trafficking of melanogenic enzymes. J Cell Biol (2006) 2.79
The Silver locus product Pmel17/gp100/Silv/ME20: controversial in name and in function. Pigment Cell Res (2005) 2.71
Rab27a regulates phagosomal pH and NADPH oxidase recruitment to dendritic cell phagosomes. Nat Cell Biol (2007) 2.69
Inhibition of retrograde transport protects mice from lethal ricin challenge. Cell (2010) 2.67
Functions of adaptor protein (AP)-3 and AP-1 in tyrosinase sorting from endosomes to melanosomes. Mol Biol Cell (2005) 2.56
Regulation of retromer recruitment to endosomes by sequential action of Rab5 and Rab7. J Cell Biol (2008) 2.56
The interaction of IQGAP1 with the exocyst complex is required for tumor cell invasion downstream of Cdc42 and RhoA. J Cell Biol (2008) 2.39
BLOC-1 interacts with BLOC-2 and the AP-3 complex to facilitate protein trafficking on endosomes. Mol Biol Cell (2006) 2.37
ICAM-1 on exosomes from mature dendritic cells is critical for efficient naive T-cell priming. Blood (2005) 2.34
A lumenal domain-dependent pathway for sorting to intralumenal vesicles of multivesicular endosomes involved in organelle morphogenesis. Dev Cell (2006) 2.29
Secretory cytotoxic granule maturation and exocytosis require the effector protein hMunc13-4. Nat Immunol (2007) 2.28
Cell-specific ATP7A transport sustains copper-dependent tyrosinase activity in melanosomes. Nature (2008) 2.15
Proprotein convertase cleavage liberates a fibrillogenic fragment of a resident glycoprotein to initiate melanosome biogenesis. J Cell Biol (2003) 2.12
BLOC-1 is required for cargo-specific sorting from vacuolar early endosomes toward lysosome-related organelles. Mol Biol Cell (2006) 2.11
Multifocal structure of the T cell - dendritic cell synapse. Eur J Immunol (2005) 2.09
Diverse subpopulations of vesicles secreted by different intracellular mechanisms are present in exosome preparations obtained by differential ultracentrifugation. J Extracell Vesicles (2012) 2.06
ARF6 controls post-endocytic recycling through its downstream exocyst complex effector. J Cell Biol (2003) 2.02
AP-1 and KIF13A coordinate endosomal sorting and positioning during melanosome biogenesis. J Cell Biol (2009) 1.99
MHC II in dendritic cells is targeted to lysosomes or T cell-induced exosomes via distinct multivesicular body pathways. Traffic (2009) 1.98
Analysis of ESCRT functions in exosome biogenesis, composition and secretion highlights the heterogeneity of extracellular vesicles. J Cell Sci (2013) 1.98
Contractility of the cell rear drives invasion of breast tumor cells in 3D Matrigel. Proc Natl Acad Sci U S A (2011) 1.98
Frequent PTEN genomic alterations and activated phosphatidylinositol 3-kinase pathway in basal-like breast cancer cells. Breast Cancer Res (2008) 1.94
RalB mobilizes the exocyst to drive cell migration. Mol Cell Biol (2006) 1.91
A dual mechanism controlling the localization and function of exocytic v-SNAREs. Proc Natl Acad Sci U S A (2003) 1.86
Exosomes as potent cell-free peptide-based vaccine. I. Dendritic cell-derived exosomes transfer functional MHC class I/peptide complexes to dendritic cells. J Immunol (2004) 1.86
Endosomes, exosomes and Trojan viruses. Trends Microbiol (2004) 1.84
The tetraspanin CD63 regulates ESCRT-independent and -dependent endosomal sorting during melanogenesis. Dev Cell (2011) 1.82
Phosphatidylinositol-4,5-bisphosphate hydrolysis directs actin remodeling during phagocytosis. J Cell Biol (2005) 1.81
Oxidative stress promotes myofibroblast differentiation and tumour spreading. EMBO Mol Med (2010) 1.81
The retromer complex and clathrin define an early endosomal retrograde exit site. J Cell Sci (2007) 1.80
Endocytic traffic in animal cell cytokinesis. Curr Opin Cell Biol (2008) 1.80
Involvement of caspase-cleaved and intact adaptor protein 1 complex in endosomal remodeling in maturing dendritic cells. Nat Immunol (2005) 1.76
TI-VAMP/VAMP7 is required for optimal phagocytosis of opsonised particles in macrophages. EMBO J (2004) 1.71
Golgi-localized GAP for Cdc42 functions downstream of ARF1 to control Arp2/3 complex and F-actin dynamics. Nat Cell Biol (2005) 1.67
Matrix architecture dictates three-dimensional migration modes of human macrophages: differential involvement of proteases and podosome-like structures. J Immunol (2009) 1.65
T84-intestinal epithelial exosomes bear MHC class II/peptide complexes potentiating antigen presentation by dendritic cells. Gastroenterology (2007) 1.60
Lysosome-related organelles: unusual compartments become mainstream. Curr Opin Cell Biol (2013) 1.59
Mycobacterial p(1)-type ATPases mediate resistance to zinc poisoning in human macrophages. Cell Host Microbe (2011) 1.59
Spermatocyte cytokinesis requires rapid membrane addition mediated by ARF6 on central spindle recycling endosomes. Development (2007) 1.57
MT1-MMP-dependent invasion is regulated by TI-VAMP/VAMP7. Curr Biol (2008) 1.55
Retrovirus infection strongly enhances scrapie infectivity release in cell culture. EMBO J (2006) 1.53
ARF6 Interacts with JIP4 to control a motor switch mechanism regulating endosome traffic in cytokinesis. Curr Biol (2009) 1.52
ADP ribosylation factor 6 is activated and controls membrane delivery during phagocytosis in macrophages. J Cell Biol (2003) 1.51
Synchronization of secretory protein traffic in populations of cells. Nat Methods (2012) 1.41
Exosomes bearing HLA-DR1 molecules need dendritic cells to efficiently stimulate specific T cells. Int Immunol (2002) 1.41
Rab27A and its effector MyRIP link secretory granules to F-actin and control their motion towards release sites. J Cell Biol (2003) 1.40
Cdc42 localization and cell polarity depend on membrane traffic. J Cell Biol (2010) 1.38
Reorganisation of the dendritic actin network during cancer cell migration and invasion. Semin Cancer Biol (2007) 1.37
Dual loss of ER export and endocytic signals with altered melanosome morphology in the silver mutation of Pmel17. Mol Biol Cell (2006) 1.37
A conserved C-terminal domain of EFA6-family ARF6-guanine nucleotide exchange factors induces lengthening of microvilli-like membrane protrusions. J Cell Sci (2002) 1.35
Mouse neuroblastoma cells release prion infectivity associated with exosomal vesicles. Biol Cell (2008) 1.33
Implication of metastasis suppressor NM23-H1 in maintaining adherens junctions and limiting the invasive potential of human cancer cells. Cancer Res (2010) 1.30
Analysis of articulation between clathrin and retromer in retrograde sorting on early endosomes. Traffic (2009) 1.30
Endosomal WASH and exocyst complexes control exocytosis of MT1-MMP at invadopodia. J Cell Biol (2013) 1.28
N-terminal domains elicit formation of functional Pmel17 amyloid fibrils. J Biol Chem (2009) 1.28
Real-time observation of listeria monocytogenes-phagocyte interactions in living zebrafish larvae. Infect Immun (2009) 1.24
Exosomes: a bubble ride for prions? Traffic (2005) 1.24
Structural basis for ARF1-mediated recruitment of ARHGAP21 to Golgi membranes. EMBO J (2007) 1.24
Signaling and membrane dynamics during phagocytosis: many roads lead to the phagos(R)ome. Curr Opin Cell Biol (2004) 1.24
Rab27b regulates mast cell granule dynamics and secretion. Traffic (2007) 1.22
ARF6 GTPase controls bacterial invasion by actin remodelling. J Cell Sci (2005) 1.22