Published in Trends Immunol on March 11, 2009
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Donor selection for natural killer cell receptor genes leads to superior survival after unrelated transplantation for acute myelogenous leukemia. Blood (2010) 4.46
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Maternal activating KIRs protect against human reproductive failure mediated by fetal HLA-C2. J Clin Invest (2010) 2.19
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Unifying concepts of MHC-dependent natural killer cell education. Trends Immunol (2011) 1.85
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Neutrophil depletion impairs natural killer cell maturation, function, and homeostasis. J Exp Med (2012) 1.39
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An NKG2D-mediated human lymphoid stress surveillance response with high interindividual variation. Sci Transl Med (2011) 1.33
Structure/function of human killer cell immunoglobulin-like receptors: lessons from polymorphisms, evolution, crystal structures and mutations. Immunology (2011) 1.28
Use of allogeneic NK cells for cancer immunotherapy. Immunotherapy (2011) 1.11
MHC-dependent inhibition of uterine NK cells impedes fetal growth and decidual vascular remodelling. Nat Commun (2014) 1.10
NK cell self tolerance, responsiveness and missing self recognition. Semin Immunol (2014) 1.08
The adaptor protein Crk controls activation and inhibition of natural killer cells. Immunity (2012) 1.07
Signatures of human NK cell development and terminal differentiation. Front Immunol (2013) 1.02
CD11b and CD27 reflect distinct population and functional specialization in human natural killer cells. Immunology (2011) 0.98
How does variability of immune system genes affect placentation? Placenta (2011) 0.96
Natural killer cell tolerance persists despite significant reduction of self MHC class I on normal target cells in mice. PLoS One (2010) 0.96
NK cells: immune cross-talk and therapeutic implications. Immunotherapy (2011) 0.96
KIR and HLA loci are associated with hepatocellular carcinoma development in patients with hepatitis B virus infection: a case-control study. PLoS One (2011) 0.95
Imaging immune surveillance of individual natural killer cells confined in microwell arrays. PLoS One (2010) 0.94
Probing natural killer cell education by Ly49 receptor expression analysis and computational modelling in single MHC class I mice. PLoS One (2009) 0.93
Natural killer cells: from basic research to treatments. Front Immunol (2011) 0.93
Murine natural killer cell licensing and regulation by T regulatory cells in viral responses. Proc Natl Acad Sci U S A (2013) 0.93
Regulation of NK cell repertoire and function in the liver. Crit Rev Immunol (2011) 0.93
The evolution of natural killer cell receptors. Immunogenetics (2015) 0.92
Know Thyself: NK-Cell Inhibitory Receptors Prompt Self-Tolerance, Education, and Viral Control. Front Immunol (2014) 0.91
Impact of HCMV Infection on NK Cell Development and Function after HSCT. Front Immunol (2013) 0.90
Natural killer cell regulation - beyond the receptors. F1000Prime Rep (2014) 0.88
Natural killer cells are recruited during pulmonary tuberculosis and their ex vivo responses to mycobacteria vary between healthy human donors in association with KIR haplotype. Cell Microbiol (2012) 0.88
Development of a novel multiplex PCR assay to detect functional subtypes of KIR3DL1 alleles. PLoS One (2014) 0.88
NK cell activation in human hantavirus infection explained by virus-induced IL-15/IL15Rα expression. PLoS Pathog (2014) 0.87
Natural killer cells and their receptors in multiple sclerosis. Brain (2012) 0.87
Enrichment of CD56(dim)KIR + CD57 + highly cytotoxic NK cells in tumour-infiltrated lymph nodes of melanoma patients. Nat Commun (2014) 0.87
Human NK cells differ more in their KIR2DL1-dependent thresholds for HLA-Cw6-mediated inhibition than in their maximal killing capacity. PLoS One (2011) 0.85
CD11b(-)CD27(-) NK cells are associated with the progression of lung carcinoma. PLoS One (2013) 0.85
Human immune system variation. Nat Rev Immunol (2016) 0.84
A Higher Frequency of NKG2A+ than of NKG2A- NK Cells Responds to Autologous HIV-Infected CD4 Cells irrespective of Whether or Not They Coexpress KIR3DL1. J Virol (2015) 0.82
HLA-E-expressing pluripotent stem cells escape allogeneic responses and lysis by NK cells. Nat Biotechnol (2017) 0.82
Newtonian cell interactions shape natural killer cell education. Immunol Rev (2015) 0.81
Activation or tolerance of natural killer cells is modulated by ligand quality in a nonmonotonic manner. Biophys J (2010) 0.81
NK cell education via nonclassical MHC and non-MHC ligands. Cell Mol Immunol (2016) 0.81
PD-1 mediates functional exhaustion of activated NK cells in patients with Kaposi sarcoma. Oncotarget (2016) 0.81
Time to seroconversion in HIV-exposed subjects carrying protective versus non protective KIR3DS1/L1 and HLA-B genotypes. PLoS One (2014) 0.80
Impaired NK-cell education diminishes resistance to murine CMV infection. Eur J Immunol (2014) 0.80
Natural killer cell tolerance: control by self or self-control? Cold Spring Harb Perspect Biol (2012) 0.80
NLRC5 shields T lymphocytes from NK-cell-mediated elimination under inflammatory conditions. Nat Commun (2016) 0.80
Complement factor P is a ligand for the natural killer cell-activating receptor NKp46. Sci Immunol (2017) 0.79
Analysis of memory-like natural killer cells in human cytomegalovirus-infected children undergoing αβ+T and B cell-depleted hematopoietic stem cell transplantation for hematological malignancies. Haematologica (2015) 0.79
A New Biological Feature of Natural Killer Cells: The Recognition of Solid Tumor-Derived Cancer Stem Cells. Front Immunol (2016) 0.79
TCR affinity for thymoproteasome-dependent positively selecting peptides conditions antigen responsiveness in CD8(+) T cells. Nat Immunol (2015) 0.79
KIR2DL3 and KIR2DL1 show similar impact on licensing of human NK cells. Eur J Immunol (2015) 0.78
Analysis of the expression of KIR and HLA-Cw in a Northeast Han population. Exp Ther Med (2012) 0.78
Casting new light on the TCR. Nat Immunol (2012) 0.78
Genomic Modifiers of Natural Killer Cells, Immune Responsiveness and Lymphoid Tissue Remodeling Together Increase Host Resistance to Viral Infection. PLoS Pathog (2016) 0.78
Immunoproteasome-deficiency has no effects on NK cell education, but confers lymphocytes into targets for NK cells in infected wild-type mice. PLoS One (2011) 0.78
KIR-HLA profiling shows presence of higher frequencies of strong inhibitory KIR-ligands among prognostically poor risk AML patients. Immunogenetics (2015) 0.76
Potential of autologous NK cell therapy to eradicate leukemia: "Education is [not] the best provision for old age" -Aristotle. Oncoimmunology (2015) 0.76
Specific combinations of donor and recipient KIR-HLA genotypes predict for large differences in outcome after cord blood transplantation. Blood (2016) 0.76
Progressive changes in composition of lymphocytes in lung tissues from patients with non-small-cell lung cancer. Oncotarget (2016) 0.76
The differential impact of natural killer (NK) cell education via KIR2DL3 and KIR3DL1 on CCL4 secretion in the context of in-vitro HIV infection. Clin Exp Immunol (2016) 0.76
Microchip Screening Platform for Single Cell Assessment of NK Cell Cytotoxicity. Front Immunol (2016) 0.75
NK Cells Expressing the Inhibitory Killer Immunoglobulin-Like Receptors (iKIR) KIR2DL1, KIR2DL3 and KIR3DL1 Are Less Likely to Be CD16+ than Their iKIR Negative Counterparts. PLoS One (2016) 0.75
The Abl-1 kinase is dispensable for NK cell inhibitory signaling and is not involved in murine NK cell education. Scand J Immunol (2017) 0.75
Human Leukocyte Antigen (HLA) and Immune Regulation: How Do Classical and Non-Classical HLA Alleles Modulate Immune Response to Human Immunodeficiency Virus and Hepatitis C Virus Infections? Front Immunol (2017) 0.75
HLA mismatching favoring host-versus-graft NK cell activity via KIR3DL1 is associated with improved outcomes following lung transplantation. Am J Transplant (2017) 0.75
The Molecular Mechanism of Natural Killer Cells Function and Its Importance in Cancer Immunotherapy. Front Immunol (2017) 0.75
Liver-infiltrating CD11b(-)CD27(-) NK subsets account for NK-cell dysfunction in patients with hepatocellular carcinoma and are associated with tumor progression. Cell Mol Immunol (2016) 0.75
High mTOR activity is a hallmark of reactive natural killer cells and amplifies early signaling through activating receptors. Elife (2017) 0.75
A Role for cis Interaction between the Inhibitory Ly49A receptor and MHC class I for natural killer cell education. Immunity (2009) 2.62
Pharmacological activation of p53 triggers anticancer innate immune response through induction of ULBP2. Cell Cycle (2011) 2.43
The strength of inhibitory input during education quantitatively tunes the functional responsiveness of individual natural killer cells. Blood (2008) 2.24
NCRs and DNAM-1 mediate NK cell recognition and lysis of human and mouse melanoma cell lines in vitro and in vivo. J Clin Invest (2009) 2.08
A role for MHC class I molecules in synaptic plasticity and regeneration of neurons after axotomy. Proc Natl Acad Sci U S A (2004) 1.78
Natural killer cell education in mice with single or multiple major histocompatibility complex class I molecules. J Exp Med (2005) 1.76
A signal peptide derived from hsp60 binds HLA-E and interferes with CD94/NKG2A recognition. J Exp Med (2002) 1.67
Selective rejection of H-2-deficient lymphoma variants suggests alternative immune defence strategy. 1986. J Immunol (2005) 1.64
LIR-1 expression on lymphocytes, and cytomegalovirus disease in lung-transplant recipients. Lancet (2003) 1.59
Pillars article: Association of class I major histocompatibility heavy and light chains induced by viral peptides. Nature 1989. 340: 443-448. J Immunol (2007) 1.40
Pivotal role of KARAP/DAP12 adaptor molecule in the natural killer cell-mediated resistance to murine cytomegalovirus infection. J Exp Med (2002) 1.33
Gut microbiota accelerate tumor growth via c-jun and STAT3 phosphorylation in APCMin/+ mice. Carcinogenesis (2012) 1.31
DAP12 signaling directly augments proproliferative cytokine stimulation of NK cells during viral infections. J Immunol (2006) 1.26
Selective cytotoxic T-lymphocyte targeting of tumor immune escape variants. Nat Med (2006) 1.17
NK cells: elusive players in autoimmunity. Trends Immunol (2005) 1.17
NK cell function and antibodies mediating ADCC in HIV-1-infected viremic and controller patients. Viral Immunol (2011) 1.13
Human and murine inhibitory natural killer cell receptors transfer from natural killer cells to target cells. Proc Natl Acad Sci U S A (2004) 1.11
Human NK cells selective targeting of colon cancer-initiating cells: a role for natural cytotoxicity receptors and MHC class I molecules. J Immunol (2013) 1.11
Natural killer cells in human autoimmunity. Curr Opin Immunol (2009) 1.11
DAP12 signaling regulates plasmacytoid dendritic cell homeostasis and down-modulates their function during viral infection. J Immunol (2006) 1.11
Skewing of the NK cell repertoire by MHC class I via quantitatively controlled enrichment and contraction of specific Ly49 subsets. J Immunol (2012) 1.11
Distinct phenotype and function of NK cells in the pancreas of nonobese diabetic mice. J Immunol (2010) 1.08
Loss or mismatch of MHC class I is sufficient to trigger NK cell-mediated rejection of resting lymphocytes in vivo - role of KARAP/DAP12-dependent and -independent pathways. Eur J Immunol (2004) 1.06
Quantifying the reduction in accessibility of the inhibitory NK cell receptor Ly49A caused by binding MHC class I proteins in cis. Eur J Immunol (2007) 1.03
Activating and inhibitory receptors on synovial fluid natural killer cells of arthritis patients: role of CD94/NKG2A in control of cytokine secretion. Immunology (2007) 1.03
A structural basis for LCMV immune evasion: subversion of H-2D(b) and H-2K(b) presentation of gp33 revealed by comparative crystal structure.Analyses. Immunity (2002) 1.02
Broadly impaired NK cell function in non-obese diabetic mice is partially restored by NK cell activation in vivo and by IL-12/IL-18 in vitro. Int Immunol (2004) 1.02
In vivo tumor cell rejection induced by NK cell inhibitory receptor blockade: maintained tolerance to normal cells even in the presence of IL-2. Eur J Immunol (2010) 1.01
Classical major histocompatibility complex class I molecules in motoneurons: new actors at the neuromuscular junction. J Neurosci (2009) 0.99
Increased proportion of CD56bright natural killer cells in active and inactive systemic lupus erythematosus. Immunology (2008) 0.98
Natural killer cell tolerance persists despite significant reduction of self MHC class I on normal target cells in mice. PLoS One (2010) 0.96
Immunosuppressive treatment after solid organ transplantation and risk of post-transplant cutaneous squamous cell carcinoma. Nephrol Dial Transplant (2009) 0.96
Probing natural killer cell education by Ly49 receptor expression analysis and computational modelling in single MHC class I mice. PLoS One (2009) 0.93
Distinct and overlapping patterns of cytokine regulation of thymic and bone marrow-derived NK cell development. J Immunol (2009) 0.86
Beyond licensing and disarming: a quantitative view on NK-cell education. Eur J Immunol (2008) 0.86
Spontaneous mutations in the human CMV HLA class I homologue UL18 affect its binding to the inhibitory receptor LIR-1/ILT2/CD85j. Eur J Immunol (2006) 0.86
Altered distribution of natural killer cell subsets identified by CD56, CD27 and CD70 in primary and chronic human immunodeficiency virus-1 infection. Immunology (2007) 0.85
A structural basis for CD8+ T cell-dependent recognition of non-homologous peptide ligands: implications for molecular mimicry in autoreactivity. J Biol Chem (2005) 0.85
Increased expression of leukocyte Ig-like receptor-1 and activating role of UL18 in the response to cytomegalovirus infection. J Immunol (2007) 0.84
Natural killer cell inhibitory receptor expression in humans and mice: a closer look. Front Immunol (2013) 0.84
Increased cell-mediated immune responses in patients with recurrent herpes simplex virus type 2 meningitis. Clin Vaccine Immunol (2011) 0.84
The protean immune cell synapse: a supramolecular structure with many functions. Semin Immunol (2003) 0.83
Random aggregates in newly produced platelet units are associated with platelet activation and release of the immunomodulatory factors sCD40L and RANTES. Transfusion (2013) 0.83
Structural basis of the differential stability and receptor specificity of H-2Db in complex with murine versus human beta2-microglobulin. J Mol Biol (2005) 0.83
Simulations of the NK cell immune synapse reveal that activation thresholds can be established by inhibitory receptors acting locally. J Immunol (2011) 0.83
A modified FCCS procedure applied to Ly49A-MHC class I cis-interaction studies in cell membranes. Biophys J (2011) 0.83
MHC-dependent and -independent modulation of endogenous Ly49 receptors on NK1.1+ T lymphocytes directed by T-cell receptor type. Immunology (2003) 0.82
NK cell inhibitory receptor Ly-49C residues involved in MHC class I binding. J Immunol (2002) 0.82
Reduced antigen concentration and costimulatory blockade increase IFN-gamma secretion in naive CD8+ T cells. Eur J Immunol (2004) 0.80
A genetic defect in mice that impairs missing self recognition despite evidence for normal maturation and MHC class I-dependent education of NK cells. J Immunol (2014) 0.80
Clinical expansion of cord blood-derived T cells for use as donor lymphocyte infusion after cord blood transplantation. J Immunother (2010) 0.80
The dynamics of natural killer cell tolerance. Semin Cancer Biol (2006) 0.80
TCR repertoire dynamics in the pancreatic lymph nodes of non-obese diabetic (NOD) mice at the time of disease initiation. Mol Immunol (2008) 0.79
NK cell activation by KIR-binding antibody 1-7F9 and response to HIV-infected autologous cells in viremic and controller HIV-infected patients. Clin Immunol (2009) 0.79
Increased diabetes development and decreased function of CD4+CD25+ Treg in the absence of a functional DAP12 adaptor protein. Eur J Immunol (2008) 0.79
Models for natural killer cell repertoire formation. Clin Dev Immunol (2004) 0.78
Generation of the natural killer cell repertoire: the sequential vs. the two-step selection model. Bull Math Biol (2003) 0.78
Computational modeling of human natural killer cell development suggests a selection process regulating coexpression of KIR with CD94/NKG2A. Mol Immunol (2005) 0.77
Increased frequency and responsiveness of PSA-specific T cells after allogeneic hematopoetic stem-cell transplantation. Transplantation (2009) 0.76
The uterine cervix--a new member of the family of immunologically exceptional sites? Cancer Immun (2003) 0.76
No association between infections, HLA type and other transplant-related factors and risk of cutaneous squamous cell carcinoma in solid organ transplant recipients. Acta Derm Venereol (2012) 0.76
Expression, refolding and crystallization of murine MHC class I H-2Db in complex with human beta2-microglobulin. Acta Crystallogr Sect F Struct Biol Cryst Commun (2005) 0.76
Clever, cleverer, cleverest. Nat Immunol (2002) 0.75
AIRE deficiency leads to impaired iNKT cell development. J Autoimmun (2009) 0.75
Expansion of T-cells from the cord blood graft as a predictive tool for complications and outcome of cord blood transplantation. Clin Immunol (2012) 0.75
Impact of plastic adhesion in vitro on analysis of Th1 and Th2 cytokines and immune cell distribution from mice with multiple low-dose streptozotocin-induced diabetes. J Immunol Methods (2005) 0.75
Severe Transplantation-Mediated Alloimmune Thrombocytopenia in 2 Recipients of Organs From the Same Donor. Transplantation (2017) 0.75
First International Meeting of the Thematic Centre for Immune Modulatory Therapies for Autoimmunity and Cancer (IMTAC) 13-14 June 2011, Ljusterö, Sweden. Cancer Immunol Immunother (2012) 0.75
Natural killer cells in cancer. Semin Cancer Biol (2006) 0.75