PubRank

Philip A Barker

Author PubWeight™ 64.46‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 cIAP1 and cIAP2 facilitate cancer cell survival by functioning as E3 ligases that promote RIP1 ubiquitination. Mol Cell 2008 5.89
2 De novo mutations in the gene encoding the synaptic scaffolding protein SHANK3 in patients ascertained for schizophrenia. Proc Natl Acad Sci U S A 2010 3.13
3 Cellular inhibitors of apoptosis cIAP1 and cIAP2 are required for innate immunity signaling by the pattern recognition receptors NOD1 and NOD2. Immunity 2009 2.91
4 Neurotrophin signaling through the p75 neurotrophin receptor. Prog Neurobiol 2002 2.39
5 Nuclear factor kappa B signaling regulates neuronal morphology and cocaine reward. J Neurosci 2009 2.25
6 Constitutive nuclear factor-kappa B activity is required for central neuron survival. J Neurosci 2002 1.95
7 Vasculature guides migrating neuronal precursors in the adult mammalian forebrain via brain-derived neurotrophic factor signaling. J Neurosci 2009 1.89
8 Ligand-dependent cleavage of the P75 neurotrophin receptor is necessary for NRIF nuclear translocation and apoptosis in sympathetic neurons. Neuron 2006 1.74
9 An inactivating caspase 11 passenger mutation originating from the 129 murine strain in mice targeted for c-IAP1. Biochem J 2012 1.71
10 Mutations in the calcium-related gene IL1RAPL1 are associated with autism. Hum Mol Genet 2008 1.66
11 AEG3482 is an antiapoptotic compound that inhibits Jun kinase activity and cell death through induced expression of heat shock protein 70. Chem Biol 2006 1.64
12 NRAGE, a p75 neurotrophin receptor-interacting protein, induces caspase activation and cell death through a JNK-dependent mitochondrial pathway. J Biol Chem 2002 1.48
13 Apoptosis induced by p75NTR overexpression requires Jun kinase-dependent phosphorylation of Bad. J Neurosci 2003 1.36
14 The epilepsy gene LGI1 encodes a secreted glycoprotein that binds to the cell surface. Hum Mol Genet 2006 1.29
15 The p75 neurotrophin receptor: multiple interactors and numerous functions. Prog Brain Res 2004 1.26
16 Excitotoxic death of retinal neurons in vivo occurs via a non-cell-autonomous mechanism. J Neurosci 2009 1.26
17 Characterization of the c-Jun N-terminal kinase-BimEL signaling pathway in neuronal apoptosis. J Neurosci 2004 1.24
18 Nuclear factor-kappaB induced by doxorubicin is deficient in phosphorylation and acetylation and represses nuclear factor-kappaB-dependent transcription in cancer cells. Cancer Res 2005 1.16
19 LGI1 is a Nogo receptor 1 ligand that antagonizes myelin-based growth inhibition. J Neurosci 2010 1.14
20 K252a and CEP1347 are neuroprotective compounds that inhibit mixed-lineage kinase-3 and induce activation of Akt and ERK. J Biol Chem 2002 1.12
21 ProNGF induces TNFalpha-dependent death of retinal ganglion cells through a p75NTR non-cell-autonomous signaling pathway. Proc Natl Acad Sci U S A 2010 1.10
22 Protein kinase A activation promotes plasma membrane insertion of DCC from an intracellular pool: A novel mechanism regulating commissural axon extension. J Neurosci 2004 1.10
23 Tumor necrosis factor-alpha triggers mucus production in airway epithelium through an IkappaB kinase beta-dependent mechanism. J Biol Chem 2005 1.09
24 p75 neurotrophin receptor reduces ligand-induced Trk receptor ubiquitination and delays Trk receptor internalization and degradation. EMBO Rep 2005 1.07
25 TRPC channels underlie cholinergic plateau potentials and persistent activity in entorhinal cortex. Hippocampus 2011 1.06
26 Proneurotrophins require endocytosis and intracellular proteolysis to induce TrkA activation. J Biol Chem 2008 1.05
27 Edar and Troy signalling pathways act redundantly to regulate initiation of hair follicle development. Hum Mol Genet 2008 1.05
28 A pro-apoptotic fragment of the p75 neurotrophin receptor is expressed in p75NTRExonIV null mice. J Neurosci 2004 1.02
29 Soluble adenylyl cyclase is not required for axon guidance to netrin-1. J Neurosci 2008 0.99
30 XIAP regulates caspase activity in degenerating axons. Cell Rep 2013 0.99
31 Hypo-osmolar stress induces p75NTR expression by activating Sp1-dependent transcription. J Neurosci 2007 0.98
32 Apoptotic sensitivity of murine IAP-deficient cells. Biochem J 2008 0.97
33 The p75NTR intracellular domain generated by neurotrophin-induced receptor cleavage potentiates Trk signaling. J Cell Sci 2010 0.96
34 Stabilization of p73 by nuclear IkappaB kinase-alpha mediates cisplatin-induced apoptosis. J Biol Chem 2007 0.95
35 Something old, something new: BDNF-induced neuron survival requires TRPC channel function. Nat Neurosci 2007 0.91
36 p75 neurotrophin receptor cleavage by α- and γ-secretases is required for neurotrophin-mediated proliferation of brain tumor-initiating cells. J Biol Chem 2014 0.91
37 ASPP1/2 regulate p53-dependent death of retinal ganglion cells through PUMA and Fas/CD95 activation in vivo. J Neurosci 2013 0.89
38 Trk-dependent ADAM17 activation facilitates neurotrophin survival signaling. FASEB J 2011 0.88
39 TRAF6-dependent NF-kB transcriptional activity during mouse development. Dev Dyn 2004 0.88
40 Expression analysis of a novel p75(NTR) signaling protein, which regulates cell cycle progression and apoptosis. Mech Dev 2002 0.86
41 Developing a methodology for carbon isotope analysis of lacustrine diatoms. Rapid Commun Mass Spectrom 2011 0.85
42 Interaction and antagonistic roles of NF-κB and Hes6 in the regulation of cortical neurogenesis. Mol Cell Biol 2013 0.81
43 Stress-induced expression of the p75 neurotrophin receptor is regulated by O-GlcNAcylation of the Sp1 transcription factor. J Neurochem 2010 0.80
44 Photic injury promotes cleavage of p75NTR by TACE and nuclear trafficking of the p75 intracellular domain. Mol Cell Neurosci 2007 0.80
45 Wengen, the sole tumour necrosis factor receptor in Drosophila, collaborates with moesin to control photoreceptor axon targeting during development. PLoS One 2013 0.80
46 Neurotrophins in the regulation of cellular survival and death. Handb Exp Pharmacol 2014 0.79
47 p75NTR-dependent Rac1 activation requires receptor cleavage and activation of an NRAGE and NEDD9 signaling cascade. J Cell Sci 2015 0.77
48 Observations on the function of nuclear factor kappa B (NF-kappaB) in the survival of adult primary sensory neurons after nerve injury. Mol Cell Neurosci 2008 0.77
49 Getting RIP'd Stunts Your Growth. Neuron 2005 0.75