Published in BMC Microbiol on April 21, 2009
Critical role for interleukin-1beta (IL-1beta) during Chlamydia muridarum genital infection and bacterial replication-independent secretion of IL-1beta in mouse macrophages. Infect Immun (2009) 1.19
New frontiers in type III secretion biology: the Chlamydia perspective. Infect Immun (2013) 1.06
Identification of Chlamydia trachomatis CT621, a protein delivered through the type III secretion system to the host cell cytoplasm and nucleus. FEMS Immunol Med Microbiol (2009) 1.02
Promoters for Chlamydia type III secretion genes show a differential response to DNA supercoiling that correlates with temporal expression pattern. J Bacteriol (2010) 0.92
Mutations in hemG mediate resistance to salicylidene acylhydrazides, demonstrating a novel link between protoporphyrinogen oxidase (HemG) and Chlamydia trachomatis infectivity. J Bacteriol (2013) 0.89
Cytosporone B, an inhibitor of the type III secretion system of Salmonella enterica serovar Typhimurium. Antimicrob Agents Chemother (2013) 0.88
The bacterial type III secretion system as a target for developing new antibiotics. Chem Biol Drug Des (2015) 0.81
Small molecules aimed at type III secretion systems to inhibit bacterial virulence. Medchemcomm (2013) 0.79
Chlamydia psittaci comparative genomics reveals intraspecies variations in the putative outer membrane and type III secretion system genes. Microbiology (2015) 0.79
The host-encoded Heme Regulated Inhibitor (HRI) facilitates virulence-associated activities of bacterial pathogens. PLoS One (2013) 0.77
Conserved type III secretion system exerts important roles in Chlamydia trachomatis. Int J Clin Exp Pathol (2014) 0.77
Viral infection: Moving through complex and dynamic cell-membrane structures. Commun Integr Biol (2011) 0.76
The type III secretion system (T3SS) of Chlamydophila psittaci is involved in the host inflammatory response by activating the JNK/ERK signaling pathway. Biomed Res Int (2015) 0.75
Discovery of YopE Inhibitors by Pharmacophore-Based Virtual Screening and Docking. ISRN Bioinform (2013) 0.75
The type III secretion injectisome. Nat Rev Microbiol (2006) 7.62
A chlamydial type III translocated protein is tyrosine-phosphorylated at the site of entry and associated with recruitment of actin. Proc Natl Acad Sci U S A (2004) 3.44
Cloning and characterization of a Chlamydia psittaci gene coding for a protein localized in the inclusion membrane of infected cells. Mol Microbiol (1995) 2.64
Evidence for the secretion of Chlamydia trachomatis CopN by a type III secretion mechanism. Mol Microbiol (2000) 2.21
Vesicular interactions of the Chlamydia trachomatis inclusion are determined by chlamydial early protein synthesis rather than route of entry. Infect Immun (1996) 2.18
Identification and characterization of a Chlamydia trachomatis early operon encoding four novel inclusion membrane proteins. Mol Microbiol (1999) 2.18
Chlamydia trachomatis induces remodeling of the actin cytoskeleton during attachment and entry into HeLa cells. Infect Immun (2002) 2.12
Chlamydia trachomatis type III secretion: evidence for a functional apparatus during early-cycle development. Mol Microbiol (2003) 2.03
Small-molecule inhibitors specifically targeting type III secretion. Infect Immun (2005) 2.02
A small-molecule inhibitor of type III secretion inhibits different stages of the infectious cycle of Chlamydia trachomatis. Proc Natl Acad Sci U S A (2006) 2.01
Secretion of predicted Inc proteins of Chlamydia pneumoniae by a heterologous type III machinery. Mol Microbiol (2001) 1.85
Treatment of Chlamydia trachomatis with a small molecule inhibitor of the Yersinia type III secretion system disrupts progression of the chlamydial developmental cycle. Mol Microbiol (2006) 1.84
Chlamydial TARP is a bacterial nucleator of actin. Proc Natl Acad Sci U S A (2006) 1.81
Chlamydia effector proteins and new insights into chlamydial cellular microbiology. Curr Opin Microbiol (2008) 1.75
Recent insights into the mechanisms of Chlamydia entry. Cell Microbiol (2005) 1.74
Chlamydial entry involves TARP binding of guanine nucleotide exchange factors. PLoS Pathog (2008) 1.63
Requirement for the Rac GTPase in Chlamydia trachomatis invasion of non-phagocytic cells. Traffic (2004) 1.55
Small molecule inhibitors of type III secretion in Yersinia block the Chlamydia pneumoniae infection cycle. FEBS Lett (2007) 1.50
Salicylidene acylhydrazides that affect type III protein secretion in Salmonella enterica serovar typhimurium. Antimicrob Agents Chemother (2007) 1.43
Small-molecule type III secretion system inhibitors block assembly of the Shigella type III secreton. J Bacteriol (2008) 1.24
Analysis of Chlamydia caviae entry sites and involvement of Cdc42 and Rac activity. J Cell Sci (2004) 1.22
ARF6 GTPase controls bacterial invasion by actin remodelling. J Cell Sci (2005) 1.22
Chlamydia trachomatis tarp is phosphorylated by src family tyrosine kinases. Biochem Biophys Res Commun (2008) 1.21
Reversal of the antichlamydial activity of putative type III secretion inhibitors by iron. Infect Immun (2007) 1.20
Bioinformatic and biochemical evidence for the identification of the type III secretion system needle protein of Chlamydia trachomatis. J Bacteriol (2007) 1.12
Type III secretion in Chlamydia: a case of déjà vu? Mol Microbiol (1998) 1.07
The Chlamydia pneumoniae type III secretion-related lcrH gene clusters are developmentally expressed operons. J Bacteriol (2005) 0.99
Role of Escherichia coli curli operons in directing amyloid fiber formation. Science (2002) 5.58
An endonuclease allows Streptococcus pneumoniae to escape from neutrophil extracellular traps. Curr Biol (2006) 3.69
Functional adaptation of BabA, the H. pylori ABO blood group antigen binding adhesin. Science (2004) 3.06
Clinical and microbiological characteristics of severe Streptococcus pyogenes disease in Europe. J Clin Microbiol (2009) 2.80
Evolutionary pathway to increased virulence and epidemic group A Streptococcus disease derived from 3,615 genome sequences. Proc Natl Acad Sci U S A (2014) 2.63
Toll-like receptor 4 resides in the Golgi apparatus and colocalizes with internalized lipopolysaccharide in intestinal epithelial cells. J Exp Med (2002) 2.53
Bacterial adhesins in host-microbe interactions. Cell Host Microbe (2009) 2.43
Bacterial strategies for overcoming host innate and adaptive immune responses. Nat Immunol (2002) 2.33
The Salmonella enterica subspecies I specific centisome 7 genomic island encodes novel protein families present in bacteria living in close contact with eukaryotic cells. Res Microbiol (2002) 2.18
Discovery of a novel class of highly conserved vaccine antigens using genomic scale antigenic fingerprinting of pneumococcus with human antibodies. J Exp Med (2007) 2.11
Intracellular recognition of lipopolysaccharide by toll-like receptor 4 in intestinal epithelial cells. J Exp Med (2003) 2.05
A small-molecule inhibitor of type III secretion inhibits different stages of the infectious cycle of Chlamydia trachomatis. Proc Natl Acad Sci U S A (2006) 2.01
Capsule and D-alanylated lipoteichoic acids protect Streptococcus pneumoniae against neutrophil extracellular traps. Cell Microbiol (2007) 1.99
Histone methylation by NUE, a novel nuclear effector of the intracellular pathogen Chlamydia trachomatis. PLoS Pathog (2010) 1.98
Clinical utility of PCR for common viruses in acute respiratory illness. Pediatrics (2014) 1.86
Intraclonal variations among Streptococcus pneumoniae isolates influence the likelihood of invasive disease in children. J Infect Dis (2013) 1.84
Polynucleotide phosphorylase is a global regulator of virulence and persistency in Salmonella enterica. Proc Natl Acad Sci U S A (2002) 1.83
Epidemiology of severe Streptococcus pyogenes disease in Europe. J Clin Microbiol (2008) 1.81
Neutrophil extracellular traps: casting the NET over pathogenesis. Curr Opin Microbiol (2007) 1.80
Recent insights into the mechanisms of Chlamydia entry. Cell Microbiol (2005) 1.74
Toll-like receptor 9 acts at an early stage in host defence against pneumococcal infection. Cell Microbiol (2006) 1.62
Emergence of hypervirulent mutants resistant to early clearance during systemic serotype 1 pneumococcal infection in mice and humans. J Infect Dis (2014) 1.62
Myeloid differentiation factor 88-dependent signalling controls bacterial growth during colonization and systemic pneumococcal disease in mice. Cell Microbiol (2005) 1.59
SNARE protein mimicry by an intracellular bacterium. PLoS Pathog (2008) 1.52
Virulence in mice of pneumococcal clonal types with known invasive disease potential in humans. J Infect Dis (2005) 1.51
Small molecule inhibitors of type III secretion in Yersinia block the Chlamydia pneumoniae infection cycle. FEBS Lett (2007) 1.50
Streptococcus pneumoniae contains 3 rlrA pilus variants that are clonally related. J Infect Dis (2008) 1.49
The Escherichia coli BarA-UvrY two-component system is needed for efficient switching between glycolytic and gluconeogenic carbon sources. J Bacteriol (2003) 1.44
Conservation of the biochemical properties of IncA from Chlamydia trachomatis and Chlamydia caviae: oligomerization of IncA mediates interaction between facing membranes. J Biol Chem (2004) 1.41
ETosis: a novel cell death pathway. Sci Signal (2008) 1.41
Gastric mucosal recognition of Helicobacter pylori is independent of Toll-like receptor 4. J Infect Dis (2003) 1.39
Roles of curli, cellulose and BapA in Salmonella biofilm morphology studied by atomic force microscopy. BMC Microbiol (2007) 1.33
The rise and fall of bacterial clones: Streptococcus pneumoniae. Nat Rev Microbiol (2008) 1.32
Correlation between cag pathogenicity island composition and Helicobacter pylori-associated gastroduodenal disease. Infect Immun (2003) 1.32
Structural requirements for TLR4-mediated LPS signalling: a biological role for LPS modifications. Microbes Infect (2003) 1.30
High abundance of virulence gene homologues in marine bacteria. Environ Microbiol (2009) 1.27
Lysogenic transfer of group A Streptococcus superantigen gene among Streptococci. J Infect Dis (2008) 1.24
LytA, major autolysin of Streptococcus pneumoniae, requires access to nascent peptidoglycan. J Biol Chem (2012) 1.23
Mechanism for sortase localization and the role of sortase localization in efficient pilus assembly in Enterococcus faecalis. J Bacteriol (2009) 1.23
ARF6 GTPase controls bacterial invasion by actin remodelling. J Cell Sci (2005) 1.22
Sortase-mediated assembly and surface topology of adhesive pneumococcal pili. Mol Microbiol (2008) 1.22
Determination of accessory gene patterns predicts the same relatedness among strains of Streptococcus pneumoniae as sequencing of housekeeping genes does and represents a novel approach in molecular epidemiology. J Clin Microbiol (2007) 1.20
Streptococcus pneumoniae evades human dendritic cell surveillance by pneumolysin expression. EMBO Mol Med (2009) 1.19
Multi-genome identification and characterization of chlamydiae-specific type III secretion substrates: the Inc proteins. BMC Genomics (2011) 1.18
Capsular expression in Streptococcus pneumoniae negatively affects spontaneous and antibiotic-induced lysis and contributes to antibiotic tolerance. J Infect Dis (2003) 1.18
Clinical isolates of Streptococcus pneumoniae bind the complement inhibitor C4b-binding protein in a PspC allele-dependent fashion. J Immunol (2009) 1.18
Dominant role of nucleotide substitution in the diversification of serotype 3 pneumococci over decades and during a single infection. PLoS Genet (2013) 1.17
Metabolic effectors secreted by bacterial pathogens: essential facilitators of plastid endosymbiosis? Plant Cell (2013) 1.16
Molecular characterization of the acid-inducible asr gene of Escherichia coli and its role in acid stress response. J Bacteriol (2003) 1.16
Developmental switch of intestinal antimicrobial peptide expression. J Exp Med (2008) 1.11
Intracellular bacteria encode inhibitory SNARE-like proteins. PLoS One (2009) 1.10
Disulfide bond formation and cysteine exclusion in gram-positive bacteria. J Biol Chem (2009) 1.09
An enzymatic ruler modulates Lewis antigen glycosylation of Helicobacter pylori LPS during persistent infection. Proc Natl Acad Sci U S A (2006) 1.09
Chlamydia co-opts the rod shape-determining proteins MreB and Pbp2 for cell division. Mol Microbiol (2012) 1.07
Two crystal structures of pneumococcal pilus sortase C provide novel insights into catalysis and substrate specificity. J Mol Biol (2009) 1.05
Lipopolysaccharide diversity evolving in Helicobacter pylori communities through genetic modifications in fucosyltransferases. PLoS One (2008) 1.02
Increased susceptibility for superinfection with Streptococcus pneumoniae during influenza virus infection is not caused by TLR7-mediated lymphopenia. PLoS One (2009) 1.02
Components of the peptidoglycan-recycling pathway modulate invasion and intracellular survival of Salmonella enterica serovar Typhimurium. Cell Microbiol (2005) 1.00
Studies on the antibacterial effects of statins--in vitro and in vivo. PLoS One (2011) 1.00
Fimbriae, pili, flagella and bacterial virulence. Contrib Microbiol (2005) 0.99
The fallacies of hope: will we discover new antibiotics to combat pathogenic bacteria in time? FEMS Microbiol Rev (2006) 0.99
TLR4-dependent recognition of lipopolysaccharide by epithelial cells requires sCD14. Cell Microbiol (2002) 0.99
Development of a real-time PCR for the detection of Chlamydia psittaci. J Med Microbiol (2006) 0.99
Activation of type III interferon genes by pathogenic bacteria in infected epithelial cells and mouse placenta. PLoS One (2012) 0.98
Characterization of a novel murine model of Staphylococcus saprophyticus urinary tract infection reveals roles for Ssp and SdrI in virulence. Infect Immun (2010) 0.96
Human monocytes promote Th1 and Th17 responses to Streptococcus pneumoniae. Infect Immun (2011) 0.96
Genetic and functional characterization of the Escherichia coli BarA-UvrY two-component system: point mutations in the HAMP linker of the BarA sensor give a dominant-negative phenotype. J Bacteriol (2005) 0.94
Identification of a family of effectors secreted by the type III secretion system that are conserved in pathogenic Chlamydiae. Infect Immun (2010) 0.93
The Escherichia coli BarA-UvrY two-component system is a virulence determinant in the urinary tract. BMC Microbiol (2006) 0.93
Focal targeting by human β-defensin 2 disrupts localized virulence factor assembly sites in Enterococcus faecalis. Proc Natl Acad Sci U S A (2013) 0.93
A changing gastric environment leads to adaptation of lipopolysaccharide variants in Helicobacter pylori populations during colonization. PLoS One (2009) 0.91
Production of reactive oxygen species is turned on and rapidly shut down in epithelial cells infected with Chlamydia trachomatis. Infect Immun (2009) 0.91
Resistance to bacitracin in Streptococcus pyogenes from oropharyngeal colonization and noninvasive infections in Portugal was caused by two clones of distinct virulence genotypes. FEMS Microbiol Lett (2009) 0.90
Pilin and sortase residues critical for endocarditis- and biofilm-associated pilus biogenesis in Enterococcus faecalis. J Bacteriol (2013) 0.90
Structural and functional insights into peptidoglycan access for the lytic amidase LytA of Streptococcus pneumoniae. MBio (2014) 0.90
Commensal pathogens, with a focus on Streptococcus pneumoniae, and interactions with the human host. Exp Cell Res (2010) 0.89