Published in Physiol Genomics on April 28, 2009
Common variants near CAV1 and CAV2 are associated with primary open-angle glaucoma in Caucasians from the USA. Hum Mol Genet (2011) 1.77
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Evidence for a role of angiopoietin-like 7 (ANGPTL7) in extracellular matrix formation of the human trabecular meshwork: implications for glaucoma. Genes Cells (2010) 1.11
Gene expression profile in human trabecular meshwork from patients with primary open-angle glaucoma. Invest Ophthalmol Vis Sci (2013) 0.93
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Development of a model of elevated intraocular pressure in rats by gene transfer of bone morphogenetic protein 2. Invest Ophthalmol Vis Sci (2013) 0.84
Cystatin a, a potential common link for mutant myocilin causative glaucoma. PLoS One (2012) 0.83
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Evaluation of SPARC as a candidate gene of juvenile-onset primary open-angle glaucoma by mutation and copy number analyses. Mol Vis (2010) 0.81
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Induction of autophagy in rats upon overexpression of wild-type and mutant optineurin gene. BMC Cell Biol (2015) 0.78
The effects of myocilin expression on functionally relevant trabecular meshwork genes: a mini-review. J Ocul Pharmacol Ther (2014) 0.78
A Novel Mgp-Cre Knock-In Mouse Reveals an Anticalcification/Antistiffness Candidate Gene in the Trabecular Meshwork and Peripapillary Scleral Region. Invest Ophthalmol Vis Sci (2015) 0.78
An In Vitro Perfusion System to Enhance Outflow Studies in Mouse Eyes. Invest Ophthalmol Vis Sci (2016) 0.77
The SPARC-related modular calcium binding protein 2 (SMOC2) gene polymorphism in primary glaucoma: a case-control study. Clin Ophthalmol (2017) 0.75
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Identification of three different truncating mutations in cytochrome P4501B1 (CYP1B1) as the principal cause of primary congenital glaucoma (Buphthalmos) in families linked to the GLC3A locus on chromosome 2p21. Hum Mol Genet (1997) 3.83
Identification of a novel adult-onset primary open-angle glaucoma (POAG) gene on 5q22.1. Hum Mol Genet (2005) 3.56
Lysyl oxidase: an oxidative enzyme and effector of cell function. Cell Mol Life Sci (2006) 3.31
Activation of a tissue-specific stress response in the aqueous outflow pathway of the eye defines the glaucoma disease phenotype. Nat Med (2001) 2.45
Effect of matrix metalloproteinases activity on outflow in perfused human organ culture. Invest Ophthalmol Vis Sci (1998) 2.43
The potential role of podoplanin in tumour invasion. Br J Cancer (2006) 2.20
Proteomics reveal Cochlin deposits associated with glaucomatous trabecular meshwork. J Biol Chem (2004) 2.00
Effects of rho-associated protein kinase inhibitor Y-27632 on intraocular pressure and outflow facility. Invest Ophthalmol Vis Sci (2001) 1.88
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Phenotype discovery by gene expression profiling: mapping of biological processes linked to BMP-2-mediated osteoblast differentiation. J Cell Biochem (2003) 1.56
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Changes in gene expression by trabecular meshwork cells in response to mechanical stretching. Invest Ophthalmol Vis Sci (2005) 1.52
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Increased expression of the WNT antagonist sFRP-1 in glaucoma elevates intraocular pressure. J Clin Invest (2008) 1.39
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Gene and protein expression changes in human trabecular meshwork cells treated with transforming growth factor-beta. Invest Ophthalmol Vis Sci (2004) 1.35
Gene expression profile of human trabecular meshwork cells in response to long-term dexamethasone exposure. Mol Vis (2006) 1.34
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Eating bone or adding it: the Wnt pathway decides. Nat Med (2007) 1.30
Tissue differential microarray analysis of dexamethasone induction reveals potential mechanisms of steroid glaucoma. Invest Ophthalmol Vis Sci (2003) 1.29
Glycosaminoglycans of the human trabecular meshwork in primary open-angle glaucoma. Invest Ophthalmol Vis Sci (1996) 1.26
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Effects of elevated intraocular pressure on outflow facility and TIGR/MYOC expression in perfused human anterior segments. Invest Ophthalmol Vis Sci (2002) 1.14
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Growth factor and cytokine modulation of trabecular meshwork matrix metalloproteinase and TIMP expression. Curr Eye Res (1998) 1.10
Gene transfer of dominant-negative RhoA increases outflow facility in perfused human anterior segment cultures. Mol Vis (2002) 1.08
Genes upregulated in the human trabecular meshwork in response to elevated intraocular pressure. Invest Ophthalmol Vis Sci (2000) 1.08
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Cyclosporine A-induced hypercalciuria in calbindin-D28k knockout and wild-type mice. Kidney Int (2002) 1.04
Matrix GLA protein function in human trabecular meshwork cells: inhibition of BMP2-induced calcification process. Invest Ophthalmol Vis Sci (2006) 1.02
Involvement of the Erk-MAP kinase pathway in TNFalpha regulation of trabecular matrix metalloproteinases and TIMPs. Invest Ophthalmol Vis Sci (2003) 1.02
Increased matrix metalloproteinases 1, 2, and 3 in the monkey uveoscleral outflow pathway after topical prostaglandin F(2 alpha)-isopropyl ester treatment. Arch Ophthalmol (2001) 1.01
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T1alpha/podoplanin is essential for capillary morphogenesis in lymphatic endothelial cells. Am J Physiol Lung Cell Mol Physiol (2008) 1.00
Presence of an established calcification marker in trabecular meshwork tissue of glaucoma donors. Invest Ophthalmol Vis Sci (2007) 0.99
Distribution of myocilin and extracellular matrix components in the corneoscleral meshwork of human eyes. Invest Ophthalmol Vis Sci (2003) 0.98
The role of age and cardiovascular disease in glaucomatous optic neuropathy. Surv Ophthalmol (1999) 0.97
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Latanoprost induces matrix metalloproteinase-1 expression in human nonpigmented ciliary epithelial cells through a cyclooxygenase-2-dependent mechanism. FASEB J (2005) 0.91
Nephroblastoma overexpressed (Nov) is a novel bone morphogenetic protein antagonist. Ann N Y Acad Sci (2007) 0.91
Matrix metalloproteinase-1 localization in the normal human uveoscleral outflow pathway. Invest Ophthalmol Vis Sci (1999) 0.90
Proteoglycan expression by human trabecular meshworks. Curr Eye Res (1997) 0.88
Anti-rhodopsin antibodies in sera from patients with normal-pressure glaucoma. Invest Ophthalmol Vis Sci (1995) 0.88
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First look at the effect of overexpression of TIGR/MYOC on the transcriptome of the human trabecular meshwork. Exp Eye Res (2006) 0.86
p38 MAP kinase pathway and stromelysin regulation in trabecular meshwork cells. Invest Ophthalmol Vis Sci (2007) 0.86
Identification and partial characterization of TGF-beta 1 receptors on trabecular cells. Invest Ophthalmol Vis Sci (1992) 0.84
Enzymes protective of oxidative damage present in all decades of life in the trabecular meshwork, as detected by two-dimensional gel electrophoresis protein maps. J Glaucoma (1996) 0.82
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Quantitative characterization of high- and low-affinity binding sites for basic fibroblast growth factor on trabecular cells of the eye. Exp Eye Res (1997) 0.77
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Synthesis and secretion of transferrin by a bovine trabecular meshwork cell line. Braz J Med Biol Res (2007) 0.76
Pseudoexfoliatio capsulae and endothelin-1 plasma levels. Acta Ophthalmol Scand Suppl (2000) 0.76
Tissue differential microarray analysis of dexamethasone induction reveals potential mechanisms of steroid glaucoma. Invest Ophthalmol Vis Sci (2003) 1.29
Genes expressed in the human trabecular meshwork during pressure-induced homeostatic response. J Cell Physiol (2004) 1.23
Self-complementary AAV virus (scAAV) safe and long-term gene transfer in the trabecular meshwork of living rats and monkeys. Invest Ophthalmol Vis Sci (2009) 1.16
Evidence for a role of angiopoietin-like 7 (ANGPTL7) in extracellular matrix formation of the human trabecular meshwork: implications for glaucoma. Genes Cells (2010) 1.11
Treatment of sheep steroid-induced ocular hypertension with a glucocorticoid-inducible MMP1 gene therapy virus. Invest Ophthalmol Vis Sci (2010) 1.11
Gene transfer of dominant-negative RhoA increases outflow facility in perfused human anterior segment cultures. Mol Vis (2002) 1.08
Matrix GLA protein function in human trabecular meshwork cells: inhibition of BMP2-induced calcification process. Invest Ophthalmol Vis Sci (2006) 1.02
Development of a gene therapy virus with a glucocorticoid-inducible MMP1 for the treatment of steroid glaucoma. Invest Ophthalmol Vis Sci (2010) 0.99
Presence of an established calcification marker in trabecular meshwork tissue of glaucoma donors. Invest Ophthalmol Vis Sci (2007) 0.99
Functional delivery of synthetic naked siRNA to the human trabecular meshwork in perfused organ cultures. Mol Vis (2007) 0.88
Stem cell therapy for ocular disorders. Arch Ophthalmol (2004) 0.88
Tissue plasminogen activator in trabecular meshwork attenuates steroid induced outflow resistance in mice. PLoS One (2013) 0.86
Expression of optineurin, a glaucoma-linked gene, is influenced by elevated intraocular pressure. Biochem Biophys Res Commun (2002) 0.85
Development of a model of elevated intraocular pressure in rats by gene transfer of bone morphogenetic protein 2. Invest Ophthalmol Vis Sci (2013) 0.84
Cystatin a, a potential common link for mutant myocilin causative glaucoma. PLoS One (2012) 0.83
Dexamethasone increases pigment epithelium-derived factor in perfused human eyes. Curr Eye Res (2008) 0.82
Differential expression of the human chloride channel genes in the trabecular meshwork under stress conditions. Exp Eye Res (2005) 0.80
Identification and functional characterization of ClC-2 chloride channels in trabecular meshwork cells. Exp Eye Res (2006) 0.80
Tissue bioengineering: potential applications to glaucoma. Arch Ophthalmol (2005) 0.80
A Novel Mgp-Cre Knock-In Mouse Reveals an Anticalcification/Antistiffness Candidate Gene in the Trabecular Meshwork and Peripapillary Scleral Region. Invest Ophthalmol Vis Sci (2015) 0.78