Published in Am J Hum Genet on May 07, 2009
A large-scale, consortium-based genomewide association study of asthma. N Engl J Med (2010) 9.17
Genomewide association between GLCCI1 and response to glucocorticoid therapy in asthma. N Engl J Med (2011) 3.80
Meta-analysis of genome-wide association studies of asthma in ethnically diverse North American populations. Nat Genet (2011) 3.68
Identification of IL6R and chromosome 11q13.5 as risk loci for asthma. Lancet (2011) 3.03
A genome-wide association study on African-ancestry populations for asthma. J Allergy Clin Immunol (2009) 2.53
Genome-wide association study of asthma identifies RAD50-IL13 and HLA-DR/DQ regions. J Allergy Clin Immunol (2010) 2.51
The genetics of asthma and allergic disease: a 21st century perspective. Immunol Rev (2011) 2.44
Genome-wide association study implicates chromosome 9q21.31 as a susceptibility locus for asthma in mexican children. PLoS Genet (2009) 2.27
Genetic determinants of lipid traits in diverse populations from the population architecture using genomics and epidemiology (PAGE) study. PLoS Genet (2011) 2.13
Assessing the reproducibility of asthma candidate gene associations, using genome-wide data. Am J Respir Crit Care Med (2009) 2.10
Genome-wide association study identifies three new susceptibility loci for adult asthma in the Japanese population. Nat Genet (2011) 2.10
Lung eQTLs to help reveal the molecular underpinnings of asthma. PLoS Genet (2012) 2.09
A genome-wide association meta-analysis of self-reported allergy identifies shared and allergy-specific susceptibility loci. Nat Genet (2013) 1.85
Genome-wide association study of body mass index in 23 000 individuals with and without asthma. Clin Exp Allergy (2013) 1.74
A genome-wide association study identifies CDHR3 as a susceptibility locus for early childhood asthma with severe exacerbations. Nat Genet (2013) 1.70
Importance of hedgehog interacting protein and other lung function genes in asthma. J Allergy Clin Immunol (2011) 1.58
Further replication studies of the EVE Consortium meta-analysis identifies 2 asthma risk loci in European Americans. J Allergy Clin Immunol (2012) 1.54
Global analysis of the impact of environmental perturbation on cis-regulation of gene expression. PLoS Genet (2011) 1.51
Gene-by-environment effect of house dust mite on purinergic receptor P2Y12 (P2RY12) and lung function in children with asthma. Clin Exp Allergy (2012) 1.50
Cis-Expression Quantitative Trait Loci Mapping Reveals Replicable Associations with Heroin Addiction in OPRM1. Biol Psychiatry (2015) 1.44
Thymic stromal lymphopoietin gene promoter polymorphisms are associated with susceptibility to bronchial asthma. Am J Respir Cell Mol Biol (2010) 1.39
Genome-wide association study identifies HLA-DP as a susceptibility gene for pediatric asthma in Asian populations. PLoS Genet (2011) 1.38
Unifying candidate gene and GWAS Approaches in Asthma. PLoS One (2010) 1.36
A genome-wide association study of the human metabolome in a community-based cohort. Cell Metab (2013) 1.33
TSLP polymorphisms are associated with asthma in a sex-specific fashion. Allergy (2010) 1.29
Association between ORMDL3, IL1RL1 and a deletion on chromosome 17q21 with asthma risk in Australia. Eur J Hum Genet (2010) 1.27
The chitinase and chitinase-like proteins: a review of genetic and functional studies in asthma and immune-mediated diseases. Curr Opin Allergy Clin Immunol (2009) 1.27
Sequencing the IL4 locus in African Americans implicates rare noncoding variants in asthma susceptibility. J Allergy Clin Immunol (2009) 1.25
Genome-wide association study of lung function decline in adults with and without asthma. J Allergy Clin Immunol (2012) 1.20
Case-control admixture mapping in Latino populations enriches for known asthma-associated genes. J Allergy Clin Immunol (2012) 1.17
Asthma genetics and personalised medicine. Lancet Respir Med (2014) 1.17
Expression analysis of asthma candidate genes during human and murine lung development. Respir Res (2011) 1.16
Genome-wide association analysis identifies 11 risk variants associated with the asthma with hay fever phenotype. J Allergy Clin Immunol (2013) 1.13
Analyses of shared genetic factors between asthma and obesity in children. J Allergy Clin Immunol (2010) 1.13
A comprehensive evaluation of potential lung function associated genes in the SpiroMeta general population sample. PLoS One (2011) 1.13
Genome-wide association studies of asthma indicate opposite immunopathogenesis direction from autoimmune diseases. J Allergy Clin Immunol (2012) 1.11
Pathogenesis of allergic airway inflammation. Curr Allergy Asthma Rep (2010) 1.11
Identification of KIF3A as a novel candidate gene for childhood asthma using RNA expression and population allelic frequencies differences. PLoS One (2011) 1.10
On genome-wide association studies for family-based designs: an integrative analysis approach combining ascertained family samples with unselected controls. Am J Hum Genet (2010) 1.09
Resequencing candidate genes implicates rare variants in asthma susceptibility. Am J Hum Genet (2012) 1.08
African ancestry is associated with asthma risk in African Americans. PLoS One (2012) 1.07
Warped linear mixed models for the genetic analysis of transformed phenotypes. Nat Commun (2014) 1.06
Cosmopolitan and ethnic-specific replication of genetic risk factors for asthma in 2 Latino populations. J Allergy Clin Immunol (2011) 1.03
Multi-ancestry genome-wide association study of 21,000 cases and 95,000 controls identifies new risk loci for atopic dermatitis. Nat Genet (2015) 1.02
A meta-analysis of genome-wide association studies for serum total IgE in diverse study populations. J Allergy Clin Immunol (2012) 1.01
PDE11A associations with asthma: results of a genome-wide association scan. J Allergy Clin Immunol (2010) 1.00
Genome-wide association studies of asthma in population-based cohorts confirm known and suggested loci and identify an additional association near HLA. PLoS One (2012) 0.99
The search for genetic variants and epigenetics related to asthma. Allergy Asthma Immunol Res (2011) 0.98
A genome-wide survey of CD4(+) lymphocyte regulatory genetic variants identifies novel asthma genes. J Allergy Clin Immunol (2014) 0.97
Asthma and chronic obstructive pulmonary disease. Curr Opin Allergy Clin Immunol (2009) 0.97
Genome-wide and follow-up studies identify CEP68 gene variants associated with risk of aspirin-intolerant asthma. PLoS One (2010) 0.97
Update in asthma 2009. Am J Respir Crit Care Med (2010) 0.96
Whole-exome sequencing of a pedigree segregating asthma. BMC Med Genet (2012) 0.95
A genome-wide association study of atopic dermatitis identifies loci with overlapping effects on asthma and psoriasis. Hum Mol Genet (2013) 0.95
MMP-9 gene variants increase the risk for non-atopic asthma in children. Respir Res (2010) 0.95
Vitamin D related genes in lung development and asthma pathogenesis. BMC Med Genomics (2013) 0.95
Genome-wide ancestry association testing identifies a common European variant on 6q14.1 as a risk factor for asthma in African American subjects. J Allergy Clin Immunol (2012) 0.95
Unraveling the genetic basis of aspirin hypersensitivity in asthma beyond arachidonate pathways. Allergy Asthma Immunol Res (2013) 0.93
Genetic risk factors for the development of allergic disease identified by genome-wide association. Clin Exp Allergy (2015) 0.93
Predicting cell types and genetic variations contributing to disease by combining GWAS and epigenetic data. PLoS One (2013) 0.92
Thymic stromal lymphopoietin (TSLP) is associated with allergic rhinitis in children with asthma. Clin Mol Allergy (2011) 0.92
The state of genome-wide association studies in pulmonary disease: a new perspective. Am J Respir Crit Care Med (2011) 0.91
Genetics of asthma and allergy: what have we learned? J Allergy Clin Immunol (2010) 0.90
Clinical utility of asthma biomarkers: from bench to bedside. Biologics (2013) 0.90
Ethnic-specific associations of rare and low-frequency DNA sequence variants with asthma. Nat Commun (2015) 0.90
Unraveling the genetic basis of asthma and allergic diseases. Allergy Asthma Immunol Res (2010) 0.89
Genetic polymorphisms and associated susceptibility to asthma. Int J Gen Med (2013) 0.89
Comprehensive genetic assessment of a functional TLR9 promoter polymorphism: no replicable association with asthma or asthma-related phenotypes. BMC Med Genet (2011) 0.89
Genome-wide prediction of childhood asthma and related phenotypes in a longitudinal birth cohort. J Allergy Clin Immunol (2012) 0.89
Whole-genome sequencing of individuals from a founder population identifies candidate genes for asthma. PLoS One (2014) 0.88
The impact of genomics on pediatric research and medicine. Pediatrics (2012) 0.87
Genome-wide association study of aspirin-exacerbated respiratory disease in a Korean population. Hum Genet (2012) 0.87
Identification of ATPAF1 as a novel candidate gene for asthma in children. J Allergy Clin Immunol (2011) 0.86
Gene-Environment Interactions in Asthma: Genetic and Epigenetic Effects. Yonsei Med J (2015) 0.86
Stratification-score matching improves correction for confounding by population stratification in case-control association studies. Genet Epidemiol (2012) 0.85
Association pattern of interleukin-1 receptor-associated kinase-4 gene polymorphisms with allergic rhinitis in a Han Chinese population. PLoS One (2011) 0.85
Integrative genetic analysis of allergic inflammation in the murine lung. Am J Respir Cell Mol Biol (2014) 0.84
Allele-specific transcription of the asthma-associated PHD finger protein 11 gene (PHF11) modulated by octamer-binding transcription factor 1 (Oct-1). J Allergy Clin Immunol (2011) 0.84
RUNX transcription factors: association with pediatric asthma and modulated by maternal smoking. Am J Physiol Lung Cell Mol Physiol (2011) 0.84
Genetic studies of the etiology of asthma. Proc Am Thorac Soc (2011) 0.84
Systems biology of asthma and allergic diseases: a multiscale approach. J Allergy Clin Immunol (2014) 0.84
Genome-wide association studies in Africans and African Americans: expanding the framework of the genomics of human traits and disease. Public Health Genomics (2014) 0.84
Genetics of allergic diseases. Immunol Allergy Clin North Am (2014) 0.83
Genome-wide association study identifies PERLD1 as asthma candidate gene. BMC Med Genet (2011) 0.83
Biomedical research, a tool to address the health issues that affect African populations. Global Health (2013) 0.83
Genetics of complex respiratory diseases: implications for pathophysiology and pharmacology studies. Br J Pharmacol (2011) 0.83
Copy number variation of the beta-defensin genes in europeans: no supporting evidence for association with lung function, chronic obstructive pulmonary disease or asthma. PLoS One (2014) 0.83
eQTL of bronchial epithelial cells and bronchial alveolar lavage deciphers GWAS-identified asthma genes. Allergy (2015) 0.83
Genome-wide association study of the age of onset of childhood asthma. J Allergy Clin Immunol (2012) 0.82
Association between reduced copy-number at T-cell receptor gamma (TCRgamma) and childhood allergic asthma: A possible role for somatic mosaicism. Mutat Res (2010) 0.81
Association of SERPINE2 with asthma. Chest (2011) 0.81
Asthma-susceptibility variants identified using probands in case-control and family-based analyses. BMC Med Genet (2010) 0.81
Integrative systems biology approaches in asthma pharmacogenomics. Pharmacogenomics (2012) 0.81
Polygenic heritability estimates in pharmacogenetics: focus on asthma and related phenotypes. Pharmacogenet Genomics (2013) 0.80
Rank-based genome-wide analysis reveals the association of ryanodine receptor-2 gene variants with childhood asthma among human populations. Hum Genomics (2013) 0.80
ST13 polymorphisms and their effect on exacerbations in steroid-treated asthmatic children and young adults. Clin Exp Allergy (2015) 0.79
Defining the contribution of SNPs identified in asthma GWAS to clinical variables in asthmatic children. BMC Med Genet (2013) 0.79
Getting from genes to function in lung disease: a National Heart, Lung, and Blood Institute workshop report. Am J Respir Crit Care Med (2010) 0.79
A genome-wide association study of bronchodilator response in asthmatics. Pharmacogenomics J (2013) 0.78
Association between tumor necrosis factor-α rs1800629 polymorphism and risk of asthma: a meta-analysis. PLoS One (2014) 0.78
PLINK: a tool set for whole-genome association and population-based linkage analyses. Am J Hum Genet (2007) 209.92
Inference of population structure using multilocus genotype data. Genetics (2000) 147.76
Meta-analysis in clinical trials. Control Clin Trials (1986) 144.91
Haploview: analysis and visualization of LD and haplotype maps. Bioinformatics (2004) 125.23
Principal components analysis corrects for stratification in genome-wide association studies. Nat Genet (2006) 115.71
The International HapMap Project. Nature (2003) 73.65
Newly identified loci that influence lipid concentrations and risk of coronary artery disease. Nat Genet (2008) 25.83
A HapMap harvest of insights into the genetics of common disease. J Clin Invest (2008) 18.31
Genetic Power Calculator: design of linkage and association genetic mapping studies of complex traits. Bioinformatics (2003) 17.92
Genetic variants regulating ORMDL3 expression contribute to the risk of childhood asthma. Nature (2007) 14.43
Implementing a unified approach to family-based tests of association. Genet Epidemiol (2000) 10.96
The Third Generation Cohort of the National Heart, Lung, and Blood Institute's Framingham Heart Study: design, recruitment, and initial examination. Am J Epidemiol (2007) 9.90
The gene encoding phosphodiesterase 4D confers risk of ischemic stroke. Nat Genet (2003) 7.37
The Childhood Asthma Management Program (CAMP): design, rationale, and methods. Childhood Asthma Management Program Research Group. Control Clin Trials (1999) 5.11
The Framingham Heart Study 100K SNP genome-wide association study resource: overview of 17 phenotype working group reports. BMC Med Genet (2007) 5.02
PBAT: tools for family-based association studies. Am J Hum Genet (2004) 4.68
Effect of variation in CHI3L1 on serum YKL-40 level, risk of asthma, and lung function. N Engl J Med (2008) 4.58
Asthma genetics 2006: the long and winding road to gene discovery. Genes Immun (2006) 4.14
On the use of general control samples for genome-wide association studies: genetic matching highlights causal variants. Am J Hum Genet (2008) 3.95
A study of twelve Southern California communities with differing levels and types of air pollution. I. Prevalence of respiratory morbidity. Am J Respir Crit Care Med (1999) 3.71
Lifecourse influences on health among British adults: effects of region of residence in childhood and adulthood. Int J Epidemiol (2007) 3.15
PDE4 inhibitors: current status. Br J Pharmacol (2008) 2.23
cAMP-Specific phosphodiesterase-4 enzymes in the cardiovascular system: a molecular toolbox for generating compartmentalized cAMP signaling. Circ Res (2007) 2.21
ORMDL3 gene is associated with asthma in three ethnically diverse populations. Am J Respir Crit Care Med (2008) 2.18
Phosphodiesterase-4 inhibitors for asthma and chronic obstructive pulmonary disease. Lancet (2005) 2.02
The 8818G allele of the agouti signaling protein (ASIP) gene is ancestral and is associated with darker skin color in African Americans. Hum Genet (2005) 1.97
Sensitization to Ascaris lumbricoides and severity of childhood asthma in Costa Rica. J Allergy Clin Immunol (2007) 1.88
Genetic variation in ORM1-like 3 (ORMDL3) and gasdermin-like (GSDML) and childhood asthma. Allergy (2008) 1.69
A polymorphism controlling ORMDL3 expression is associated with asthma that is poorly controlled by current medications. J Allergy Clin Immunol (2008) 1.65
Linkage of asthma and total serum IgE concentration to markers on chromosome 12q: evidence from Afro-Caribbean and Caucasian populations. Genomics (1996) 1.51
Absence of muscarinic cholinergic airway responses in mice deficient in the cyclic nucleotide phosphodiesterase PDE4D. Proc Natl Acad Sci U S A (2000) 1.47
ORMDL3 variants associated with asthma susceptibility in North Americans of European ancestry. J Allergy Clin Immunol (2008) 1.46
Univariate and multivariate family-based association analysis of the IL-13 ARG130GLN polymorphism in the Childhood Asthma Management Program. Genet Epidemiol (2002) 1.46
Genetic polymorphism regulating ORM1-like 3 (Saccharomyces cerevisiae) expression is associated with childhood atopic asthma in a Japanese population. J Allergy Clin Immunol (2007) 1.42
Family-based association analysis of beta2-adrenergic receptor polymorphisms in the childhood asthma management program. J Allergy Clin Immunol (2003) 1.34
The IL12B gene is associated with asthma. Am J Hum Genet (2004) 1.29
Polymorphisms in IL13, total IgE, eosinophilia, and asthma exacerbations in childhood. J Allergy Clin Immunol (2007) 1.29
Asthma and atopy are associated with chromosome 17q21 markers in Chinese children. Allergy (2009) 1.23
PDE4D plays a critical role in the control of airway smooth muscle contraction. FASEB J (2003) 1.22
Paternal asthma, mold exposure, and increased airway responsiveness among children with asthma in Costa Rica. Chest (2007) 1.06
Association between a variation in the phosphodiesterase 4D gene and bone mineral density. BMC Med Genet (2005) 1.05
Asthma onset and relapse in adult life: the British 1958 birth cohort study. Ann Allergy Asthma Immunol (2007) 1.01
Many hypotheses but no replication for the association between PDE4D and stroke. Nat Genet (2006) 0.98
Association of phosphodiesterase 4D gene polymorphisms with chronic obstructive pulmonary disease: relationship to interleukin 13 gene polymorphism. Int J Mol Med (2006) 0.96
Stroke genetics--focus on PDE4D gene. Int J Stroke (2008) 0.93
ANNOVAR: functional annotation of genetic variants from high-throughput sequencing data. Nucleic Acids Res (2010) 43.51
Biological, clinical and population relevance of 95 loci for blood lipids. Nature (2010) 28.21
Association analyses of 249,796 individuals reveal 18 new loci associated with body mass index. Nat Genet (2010) 23.08
A genome-wide association study of global gene expression. Nat Genet (2007) 22.98
Six new loci associated with body mass index highlight a neuronal influence on body weight regulation. Nat Genet (2008) 22.35
Hundreds of variants clustered in genomic loci and biological pathways affect human height. Nature (2010) 20.01
PennCNV: an integrated hidden Markov model designed for high-resolution copy number variation detection in whole-genome SNP genotyping data. Genome Res (2007) 19.07
Genome-wide meta-analysis increases to 71 the number of confirmed Crohn's disease susceptibility loci. Nat Genet (2010) 17.38
Galaxy: a web-based genome analysis tool for experimentalists. Curr Protoc Mol Biol (2010) 17.00
Host-microbe interactions have shaped the genetic architecture of inflammatory bowel disease. Nature (2012) 16.13
Common variants near MC4R are associated with fat mass, weight and risk of obesity. Nat Genet (2008) 15.94
A common genetic variant is associated with adult and childhood obesity. Science (2006) 14.95
Functional impact of global rare copy number variation in autism spectrum disorders. Nature (2010) 14.66
Rare variants create synthetic genome-wide associations. PLoS Biol (2010) 14.43
Genetic variants regulating ORMDL3 expression contribute to the risk of childhood asthma. Nature (2007) 14.43
Genetic variants in novel pathways influence blood pressure and cardiovascular disease risk. Nature (2011) 13.25
Genetic risk and a primary role for cell-mediated immune mechanisms in multiple sclerosis. Nature (2011) 13.23
Association scan of 14,500 nonsynonymous SNPs in four diseases identifies autoimmunity variants. Nat Genet (2007) 12.62
Genome-wide association study identifies eight loci associated with blood pressure. Nat Genet (2009) 12.44
Genome-wide association study of CNVs in 16,000 cases of eight common diseases and 3,000 shared controls. Nature (2010) 12.27
The genetic association database. Nat Genet (2004) 11.29
Common variants at MS4A4/MS4A6E, CD2AP, CD33 and EPHA1 are associated with late-onset Alzheimer's disease. Nat Genet (2011) 10.07
Extracting principal diagnosis, co-morbidity and smoking status for asthma research: evaluation of a natural language processing system. BMC Med Inform Decis Mak (2006) 9.98
Autism genome-wide copy number variation reveals ubiquitin and neuronal genes. Nature (2009) 9.47
Genome partitioning of genetic variation for complex traits using common SNPs. Nat Genet (2011) 8.57
The Salmeterol Multicenter Asthma Research Trial: a comparison of usual pharmacotherapy for asthma or usual pharmacotherapy plus salmeterol. Chest (2006) 8.43
Genetic relationship between five psychiatric disorders estimated from genome-wide SNPs. Nat Genet (2013) 8.02
Meta-analysis identifies 29 additional ulcerative colitis risk loci, increasing the number of confirmed associations to 47. Nat Genet (2011) 7.98
Meta-analysis identifies 13 new loci associated with waist-hip ratio and reveals sexual dimorphism in the genetic basis of fat distribution. Nat Genet (2010) 7.94
Genetic epidemiology of COPD (COPDGene) study design. COPD (2010) 7.67
Newly identified genetic risk variants for celiac disease related to the immune response. Nat Genet (2008) 7.63
Common genetic variants on 5p14.1 associate with autism spectrum disorders. Nature (2009) 7.39
Identification of ALK as a major familial neuroblastoma predisposition gene. Nature (2008) 7.38
Concept, design and implementation of a cardiovascular gene-centric 50 k SNP array for large-scale genomic association studies. PLoS One (2008) 7.16
Meta-analysis of genome scans and replication identify CD6, IRF8 and TNFRSF1A as new multiple sclerosis susceptibility loci. Nat Genet (2009) 7.16
Sleep-disordered breathing and mortality: a prospective cohort study. PLoS Med (2009) 7.06
Obstructive sleep apnea-hypopnea and incident stroke: the sleep heart health study. Am J Respir Crit Care Med (2010) 7.03
A genome-wide association study in chronic obstructive pulmonary disease (COPD): identification of two major susceptibility loci. PLoS Genet (2009) 6.93
Results of a home-based environmental intervention among urban children with asthma. N Engl J Med (2004) 6.93
Analysing biological pathways in genome-wide association studies. Nat Rev Genet (2010) 6.63
LDL-cholesterol concentrations: a genome-wide association study. Lancet (2008) 6.44
Sensitive detection of chromosomal segments of distinct ancestry in admixed populations. PLoS Genet (2009) 6.36
Disordered microbial communities in asthmatic airways. PLoS One (2010) 6.35
Asthma in exercising children exposed to ozone: a cohort study. Lancet (2002) 5.84
Genome-wide association scan meta-analysis identifies three Loci influencing adiposity and fat distribution. PLoS Genet (2009) 5.81
Prospective study of obstructive sleep apnea and incident coronary heart disease and heart failure: the sleep heart health study. Circulation (2010) 5.70
Changes in forced expiratory volume in 1 second over time in COPD. N Engl J Med (2011) 5.69
Exploiting gene-environment interaction to detect genetic associations. Hum Hered (2007) 5.63
Family-based tests for associating haplotypes with general phenotype data: application to asthma genetics. Genet Epidemiol (2004) 5.57
Pulmonary arterial enlargement and acute exacerbations of COPD. N Engl J Med (2012) 5.54
Common variants at 7p21 are associated with frontotemporal lobar degeneration with TDP-43 inclusions. Nat Genet (2010) 5.52
Optimal unified approach for rare-variant association testing with application to small-sample case-control whole-exome sequencing studies. Am J Hum Genet (2012) 5.48
Genomic screening and replication using the same data set in family-based association testing. Nat Genet (2005) 5.44
The gene encoding 5-lipoxygenase activating protein confers risk of myocardial infarction and stroke. Nat Genet (2004) 5.31
Characterisation of COPD heterogeneity in the ECLIPSE cohort. Respir Res (2010) 5.17
De novo mutations in histone-modifying genes in congenital heart disease. Nature (2013) 5.15
Problematic variation in local institutional review of a multicenter genetic epidemiology study. JAMA (2003) 5.08
Genomewide association study for susceptibility genes contributing to familial Parkinson disease. Hum Genet (2008) 5.04
The Framingham Heart Study 100K SNP genome-wide association study resource: overview of 17 phenotype working group reports. BMC Med Genet (2007) 5.02
Use of regularly scheduled albuterol treatment in asthma: genotype-stratified, randomised, placebo-controlled cross-over trial. Lancet (2004) 5.01
A locus on 19p13 modifies risk of breast cancer in BRCA1 mutation carriers and is associated with hormone receptor-negative breast cancer in the general population. Nat Genet (2010) 4.96
The interleukin-6 receptor as a target for prevention of coronary heart disease: a mendelian randomisation analysis. Lancet (2012) 4.87
Impact of in-scanner head motion on multiple measures of functional connectivity: relevance for studies of neurodevelopment in youth. Neuroimage (2012) 4.84
Replication of an association between the lymphoid tyrosine phosphatase locus (LYP/PTPN22) with type 1 diabetes, and evidence for its role as a general autoimmunity locus. Diabetes (2004) 4.81
Multiple loci associated with indices of renal function and chronic kidney disease. Nat Genet (2009) 4.78
Lung volumes and emphysema in smokers with interstitial lung abnormalities. N Engl J Med (2011) 4.75
PBAT: tools for family-based association studies. Am J Hum Genet (2004) 4.68
Genome-wide association analysis reveals putative Alzheimer's disease susceptibility loci in addition to APOE. Am J Hum Genet (2008) 4.66
Serum vitamin D levels and markers of severity of childhood asthma in Costa Rica. Am J Respir Crit Care Med (2009) 4.64
Analysis of immune-related loci identifies 48 new susceptibility variants for multiple sclerosis. Nat Genet (2013) 4.62
Genome-wide association study of ulcerative colitis identifies three new susceptibility loci, including the HNF4A region. Nat Genet (2009) 4.61
Family-based designs in the age of large-scale gene-association studies. Nat Rev Genet (2006) 4.59
Meta-analyses of genome-wide association studies identify multiple loci associated with pulmonary function. Nat Genet (2009) 4.56
A variant of the gene encoding leukotriene A4 hydrolase confers ethnicity-specific risk of myocardial infarction. Nat Genet (2005) 4.45
Random-coil behavior and the dimensions of chemically unfolded proteins. Proc Natl Acad Sci U S A (2004) 4.44
Prenatal tobacco smoke exposure affects global and gene-specific DNA methylation. Am J Respir Crit Care Med (2009) 4.44
Reagent and laboratory contamination can critically impact sequence-based microbiome analyses. BMC Biol (2014) 4.39
The Electronic Medical Records and Genomics (eMERGE) Network: past, present, and future. Genet Med (2013) 4.37
Localization of a type 1 diabetes locus in the IL2RA/CD25 region by use of tag single-nucleotide polymorphisms. Am J Hum Genet (2005) 4.36
Family-based association between Alzheimer's disease and variants in UBQLN1. N Engl J Med (2005) 4.34
Retracted Genetic signatures of exceptional longevity in humans. Science (2010) 4.33