Published in Ageing Res Rev on May 07, 2009
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Inflammaging: disturbed interplay between autophagy and inflammasomes. Aging (Albany NY) (2012) 1.58
Elevated proteasome capacity extends replicative lifespan in Saccharomyces cerevisiae. PLoS Genet (2011) 1.52
The aging heart and post-infarction left ventricular remodeling. J Am Coll Cardiol (2011) 1.39
Mitochondrial dysfunction and sarcopenia of aging: from signaling pathways to clinical trials. Int J Biochem Cell Biol (2013) 1.38
Longevity and stress in Caenorhabditis elegans. Aging (Albany NY) (2011) 1.28
Empowering adult stem cells for myocardial regeneration. Circ Res (2011) 1.25
Therapeutic targeting of autophagy in disease: biology and pharmacology. Pharmacol Rev (2013) 1.25
Aging and immune function: molecular mechanisms to interventions. Antioxid Redox Signal (2011) 1.18
Relationship between the proteasomal system and autophagy. Int J Biochem Mol Biol (2013) 1.16
Insufficient autophagy promotes bronchial epithelial cell senescence in chronic obstructive pulmonary disease. Oncoimmunology (2012) 1.12
Evolving concepts on the age-related changes in "muscle quality". J Cachexia Sarcopenia Muscle (2012) 1.08
New biomarkers probing depth of cell senescence assessed by laser scanning cytometry. Cytometry A (2010) 1.07
Role of autophagy in heart failure associated with aging. Heart Fail Rev (2010) 1.06
Mitochondrial pathways in sarcopenia of aging and disuse muscle atrophy. Biol Chem (2013) 1.04
Developmental biomarkers of aging in Caenorhabditis elegans. Dev Dyn (2010) 1.02
Angiogenesis inhibitor vasohibin-1 enhances stress resistance of endothelial cells via induction of SOD2 and SIRT1. PLoS One (2012) 1.02
Reconsidering the Role of Mitochondria in Aging. J Gerontol A Biol Sci Med Sci (2015) 0.98
Age-related changes in the function of autophagy in rat kidneys. Age (Dordr) (2011) 0.96
p62/sequestosome 1 as a regulator of proteasome inhibitor-induced autophagy in human retinal pigment epithelial cells. Mol Vis (2010) 0.95
Yeast replicative aging: a paradigm for defining conserved longevity interventions. FEMS Yeast Res (2013) 0.94
This old heart: Cardiac aging and autophagy. J Mol Cell Cardiol (2014) 0.93
Dysregulation of mitochondrial quality control processes contribute to sarcopenia in a mouse model of premature aging. PLoS One (2013) 0.92
Autophagy in aging and Alzheimer's disease: pathologic or protective? J Alzheimers Dis (2011) 0.89
Comparative cellular biogerontology: primer and prospectus. Ageing Res Rev (2010) 0.89
Context-Dependent Regulation of Autophagy by IKK-NF-κB Signaling: Impact on the Aging Process. Int J Cell Biol (2012) 0.87
The vacuole import and degradation pathway utilizes early steps of endocytosis and actin polymerization to deliver cargo proteins to the vacuole for degradation. J Biol Chem (2009) 0.87
Effects of hypoxia inducible factors-1α on autophagy and invasion of trophoblasts. Clin Exp Reprod Med (2012) 0.87
A prognostic signature of G(2) checkpoint function in melanoma cell lines. Cell Cycle (2013) 0.86
Regulation of protein degradation pathways by amino acids and insulin in skeletal muscle of neonatal pigs. J Anim Sci Biotechnol (2014) 0.83
Impaired autophagic function in rat islets with aging. Age (Dordr) (2012) 0.82
MiR-23a-depressed autophagy is a participant in PUVA- and UVB-induced premature senescence. Oncotarget (2016) 0.81
Disorders of lysosomal acidification-The emerging role of v-ATPase in aging and neurodegenerative disease. Ageing Res Rev (2016) 0.80
Senescence associated secretory phenotype profile from primary lung mice fibroblasts depends on the senescence induction stimuli. Age (Dordr) (2016) 0.80
Mitochondria and oxidative stress in heart aging. Age (Dordr) (2016) 0.79
Histone methylation and aging: lessons learned from model systems. Biochim Biophys Acta (2014) 0.79
Decreased activity of osteocyte autophagy with aging may contribute to the bone loss in senile population. Histochem Cell Biol (2014) 0.79
GRP78 at the Centre of the Stage in Cancer and Neuroprotection. Front Neurosci (2017) 0.78
Molecular alterations in proteasomes of rat liver during aging result in altered proteolytic activities. Age (Dordr) (2013) 0.78
Identification of mammary epithelial cells subject to chronic oxidative stress in mammary epithelium of young women and teenagers living in USA: implication for breast carcinogenesis. Cancer Biol Ther (2012) 0.78
Aldehyde dehydrogenase 2 activation in aged heart improves the autophagy by reducing the carbonyl modification on SIRT1. Oncotarget (2016) 0.78
Tart cherry supplementation improves working memory, hippocampal inflammation, and autophagy in aged rats. Age (Dordr) (2016) 0.77
Effects of long-term resistance exercise training on autophagy in rat skeletal muscle of chloroquine-induced sporadic inclusion body myositis. J Exerc Nutrition Biochem (2015) 0.76
Evaluation of biomass production, carotenoid level and antioxidant capacity produced by Thermus filiformis Using fractional factorial design. Braz J Microbiol (2012) 0.76
The crucial impact of lysosomes in aging and longevity. Ageing Res Rev (2016) 0.75
Effects of Aging on Kidney Graft Function, Oxidative Stress and Gene Expression after Kidney Transplantation. PLoS One (2013) 0.75
p62/SQSTM1 but not LC3 is accumulated in sarcopenic muscle of mice. J Cachexia Sarcopenia Muscle (2015) 0.75
Daily supplementation with GrandFusion(®) improves memory and learning in aged rats. Aging (Albany NY) (2017) 0.75
Dietary fat composition influences glomerular and proximal convoluted tubule cell structure and autophagic processes in kidneys from calorie-restricted mice. Aging Cell (2016) 0.75
AUTOPHAGY, MITOCHONDRIAL DYNAMICS AND RETINAL DISEASES. Asia Pac J Ophthalmol (Phila) (2015) 0.75
Time-dependent dysregulation of autophagy: Implications in aging and mitochondrial homeostasis in the kidney proximal tubule. Autophagy (2016) 0.75
Autophagy dysfunction upregulates beta-amyloid peptides via enhancing the activity of γ-secretase complex. Neuropsychiatr Dis Treat (2015) 0.75
Conserved and species-specific molecular denominators in mammalian skeletal muscle aging. NPJ Aging Mech Dis (2017) 0.75
Guidelines for the use and interpretation of assays for monitoring autophagy. Autophagy (2012) 20.08
MAPK-mediated bimodal gene expression and adaptive gradient sensing in yeast. Nature (2007) 3.23
A genome-wide scan identifies mutations in the gene encoding phosphodiesterase 11A4 (PDE11A) in individuals with adrenocortical hyperplasia. Nat Genet (2006) 2.86
A protective and broadly cross-neutralizing epitope of human papillomavirus L2. J Virol (2007) 2.36
Adrenal hyperplasia and adenomas are associated with inhibition of phosphodiesterase 11A in carriers of PDE11A sequence variants that are frequent in the population. Cancer Res (2006) 1.72
Reengineered salivary glands are stable endogenous bioreactors for systemic gene therapeutics. Proc Natl Acad Sci U S A (2004) 1.64
Depletion of type IA regulatory subunit (RIalpha) of protein kinase A (PKA) in mammalian cells and tissues activates mTOR and causes autophagic deficiency. Hum Mol Genet (2006) 1.47
Cloning and characterization of a bovine adeno-associated virus. J Virol (2004) 1.46
mTOR kinase and the regulatory subunit of protein kinase A (PRKAR1A) spatially and functionally interact during autophagosome maturation. Autophagy (2007) 1.43
Protein kinase A effects of an expressed PRKAR1A mutation associated with aggressive tumors. Cancer Res (2008) 1.39
In vitro functional studies of naturally occurring pathogenic PRKAR1A mutations that are not subject to nonsense mRNA decay. Hum Mutat (2008) 1.39
PRKAR1A Mutations and protein kinase A interactions with other signaling pathways in the adrenal cortex. J Clin Endocrinol Metab (2006) 1.36
Large deletions of the PRKAR1A gene in Carney complex. Clin Cancer Res (2008) 1.36
Vaccination of healthy volunteers with human papillomavirus type 16 L2E7E6 fusion protein induces serum antibody that neutralizes across papillomavirus species. Cancer Res (2006) 1.26
Salivary glands as a potential gene transfer target for gene therapeutics of some monogenetic endocrine disorders. J Endocrinol (2005) 1.23
The hepatitis E virus open reading frame 3 product interacts with microtubules and interferes with their dynamics. J Virol (2009) 1.12
PRKAR1A inactivation leads to increased proliferation and decreased apoptosis in human B lymphocytes. Cancer Res (2006) 1.09
An immortalized human cell line bearing a PRKAR1A-inactivating mutation: effects of overexpression of the wild-type Allele and other protein kinase A subunits. J Clin Endocrinol Metab (2007) 1.07
Mouse Prkar1a haploinsufficiency leads to an increase in tumors in the Trp53+/- or Rb1+/- backgrounds and chemically induced skin papillomas by dysregulation of the cell cycle and Wnt signaling. Hum Mol Genet (2010) 1.05
A novel bovine virus efficiently transduces inner ear neuroepithelial cells. Mol Ther (2005) 1.05
Immune responses following salivary gland administration of recombinant adeno-associated virus serotype 2 vectors. J Gene Med (2005) 1.02
Pituitary magnetic resonance imaging in 15 patients with Prop1 gene mutations: pituitary enlargement may originate from the intermediate lobe. J Clin Endocrinol Metab (2004) 0.99
Development of a nucleocapsid-based human coronavirus immunoassay and estimates of individuals exposed to coronavirus in a U.S. metropolitan population. Clin Vaccine Immunol (2008) 0.92
Subunit and whole molecule specificity of the anti-bovine casein immune response in recent onset psychosis and schizophrenia. Schizophr Res (2010) 0.89
Autophagy in aging and in neurodegenerative disorders. Hormones (Athens) (2008) 0.89
Borrelia burgdorferi BBA52 is a potential target for transmission blocking Lyme disease vaccine. Vaccine (2011) 0.89
Retinoic acid induces autophagosome maturation through redistribution of the cation-independent mannose-6-phosphate receptor. Antioxid Redox Signal (2011) 0.88
Coronavirus immunoreactivity in individuals with a recent onset of psychotic symptoms. Schizophr Bull (2009) 0.86
Generation of a tumor vaccine candidate based on conjugation of a MUC1 peptide to polyionic papillomavirus virus-like particles. Cancer Immunol Immunother (2010) 0.86
Autophagy: a target for retinoic acids. Autophagy (2010) 0.85
Viral FLICE inhibitory protein of rhesus monkey rhadinovirus inhibits apoptosis by enhancing autophagosome formation. PLoS One (2012) 0.80
Cloning of partial cDNAs for the chicken glucocorticoid and mineralocorticoid receptors and characterization of mRNA levels in the anterior pituitary gland during chick embryonic development. Domest Anim Endocrinol (2006) 0.78
Ontogeny of pituitary thyrotrophs and regulation by endogenous thyroid hormone feedback in the chick embryo. J Endocrinol (2005) 0.78
Identification of the chicken growth hormone-releasing hormone receptor (GHRH-R) mRNA and gene: regulation of anterior pituitary GHRH-R mRNA levels by homologous and heterologous hormones. Endocrinology (2006) 0.78
Pathology and molecular genetics of the pituitary gland in patients with the 'complex of spotty skin pigmentation, myxomas, endocrine overactivity and schwannomas' (Carney complex). Front Horm Res (2004) 0.77
Genetics of the adrenal gland. Rev Endocr Metab Disord (2004) 0.76
8-Cl-adenosine inhibits proliferation and causes apoptosis in B-lymphocytes via protein kinase A-dependent and independent effects: implications for treatment of Carney complex-associated tumors. J Clin Endocrinol Metab (2009) 0.75
Ovulation induction and successful pregnancy outcome in two patients with Prop1 gene mutations. Fertil Steril (2004) 0.75