Published in Gastroenterology on May 07, 2009
Animals in a bacterial world, a new imperative for the life sciences. Proc Natl Acad Sci U S A (2013) 5.03
Homeostasis and inflammation in the intestine. Cell (2010) 4.60
The microbiome and butyrate regulate energy metabolism and autophagy in the mammalian colon. Cell Metab (2011) 3.54
Evidence for a core gut microbiota in the zebrafish. ISME J (2011) 3.22
Molecular characterization of mucosal adherent bacteria and associations with colorectal adenomas. Gut Microbes (2010) 2.70
Small intestinal bacterial overgrowth syndrome. World J Gastroenterol (2010) 1.99
Microbes inside--from diversity to function: the case of Akkermansia. ISME J (2012) 1.80
Host-microbe interactions in the developing zebrafish. Curr Opin Immunol (2010) 1.76
Alterations in the gut microbiome of children with severe ulcerative colitis. Inflamm Bowel Dis (2011) 1.42
Microbial colonization induces dynamic temporal and spatial patterns of NF-κB activation in the zebrafish digestive tract. Gastroenterology (2011) 1.39
Molecular modulation of intestinal epithelial barrier: contribution of microbiota. J Biomed Biotechnol (2010) 1.25
The intestinal microbiome and the leaky gut as therapeutic targets in alcoholic liver disease. Front Physiol (2012) 1.07
PhyloChip microarray analysis reveals altered gastrointestinal microbial communities in a rat model of colonic hypersensitivity. Neurogastroenterol Motil (2010) 1.03
Discovery of a novel and rich source of gluten-degrading microbial enzymes in the oral cavity. PLoS One (2010) 1.00
Identification of Human Intestinal Microbiota of 92 Men by Data Mining for 5 Characteristics, i.e., Age, BMI, Smoking Habit, Cessation Period of Previous Smokers and Drinking Habit. Biosci Microbiota Food Health (2013) 0.96
Identification of Rothia bacteria as gluten-degrading natural colonizers of the upper gastro-intestinal tract. PLoS One (2011) 0.96
Bacterial translocation and changes in the intestinal microbiome associated with alcoholic liver disease. World J Hepatol (2012) 0.95
Microbiota modulate transcription in the intestinal epithelium without remodeling the accessible chromatin landscape. Genome Res (2014) 0.91
Intronic cis-regulatory modules mediate tissue-specific and microbial control of angptl4/fiaf transcription. PLoS Genet (2012) 0.89
The effects of chemical interactions and culture history on the colonization of structured habitats by competing bacterial populations. BMC Microbiol (2014) 0.82
Microbiota and nonalcoholic steatohepatitis. Semin Immunopathol (2013) 0.82
Mucosal adherent bacterial dysbiosis in patients with colorectal adenomas. Sci Rep (2016) 0.81
Characterization of housing-related spontaneous variations of gut microbiota and expression of toll-like receptors 2 and 4 in rats. Microb Ecol (2010) 0.81
Bacterial protein AvrA stabilizes intestinal epithelial tight junctions via blockage of the C-Jun N-terminal kinase pathway. Tissue Barriers (2015) 0.80
Environment-related adaptive changes of gut commensal microbiota do not alter colonic toll-like receptors but modulate the local expression of sensory-related systems in rats. Microb Ecol (2013) 0.79
Study Bacteria-Host Interactions Using Intestinal Organoids. Methods Mol Biol (2016) 0.76
A core gut microbiome in obese and lean twins. Nature (2008) 52.30
Diversity of the human intestinal microbial flora. Science (2005) 49.64
An obesity-associated gut microbiome with increased capacity for energy harvest. Nature (2006) 44.35
Rapid determination of 16S ribosomal RNA sequences for phylogenetic analyses. Proc Natl Acad Sci U S A (1985) 37.69
Microbial ecology: human gut microbes associated with obesity. Nature (2006) 36.98
Obesity alters gut microbial ecology. Proc Natl Acad Sci U S A (2005) 33.66
Metagenomic analysis of the human distal gut microbiome. Science (2006) 29.76
Recognition of commensal microflora by toll-like receptors is required for intestinal homeostasis. Cell (2004) 29.32
The human microbiome project. Nature (2007) 28.53
The gut microbiota as an environmental factor that regulates fat storage. Proc Natl Acad Sci U S A (2004) 26.56
Host-bacterial mutualism in the human intestine. Science (2005) 26.39
Evolution of mammals and their gut microbes. Science (2008) 21.40
Molecular-phylogenetic characterization of microbial community imbalances in human inflammatory bowel diseases. Proc Natl Acad Sci U S A (2007) 20.60
Development of the human infant intestinal microbiota. PLoS Biol (2007) 18.91
Ecological and evolutionary forces shaping microbial diversity in the human intestine. Cell (2006) 18.83
Microbial ecology of the gastrointestinal tract. Annu Rev Microbiol (1977) 17.41
The pervasive effects of an antibiotic on the human gut microbiota, as revealed by deep 16S rRNA sequencing. PLoS Biol (2008) 16.57
IKKbeta links inflammation and tumorigenesis in a mouse model of colitis-associated cancer. Cell (2004) 15.82
An immunomodulatory molecule of symbiotic bacteria directs maturation of the host immune system. Cell (2005) 15.46
Genome analysis of multiple pathogenic isolates of Streptococcus agalactiae: implications for the microbial "pan-genome". Proc Natl Acad Sci U S A (2005) 14.59
Faecalibacterium prausnitzii is an anti-inflammatory commensal bacterium identified by gut microbiota analysis of Crohn disease patients. Proc Natl Acad Sci U S A (2008) 14.18
Counting the uncountable: statistical approaches to estimating microbial diversity. Appl Environ Microbiol (2001) 14.07
A genomic view of the human-Bacteroides thetaiotaomicron symbiosis. Science (2003) 12.57
Innate immunity and intestinal microbiota in the development of Type 1 diabetes. Nature (2008) 12.45
Diet-induced obesity is linked to marked but reversible alterations in the mouse distal gut microbiome. Cell Host Microbe (2008) 11.97
Effect of genome size and rrn gene copy number on PCR amplification of 16S rRNA genes from a mixture of bacterial species. Appl Environ Microbiol (1995) 11.09
Functional metagenomic profiling of nine biomes. Nature (2008) 11.00
An ecological and evolutionary perspective on human-microbe mutualism and disease. Nature (2007) 10.92
Mechanisms underlying the resistance to diet-induced obesity in germ-free mice. Proc Natl Acad Sci U S A (2007) 9.71
Reciprocal gut microbiota transplants from zebrafish and mice to germ-free recipients reveal host habitat selection. Cell (2006) 9.64
Microbial influences in inflammatory bowel diseases. Gastroenterology (2008) 9.20
Glycan foraging in vivo by an intestine-adapted bacterial symbiont. Science (2005) 9.08
Local dispersal promotes biodiversity in a real-life game of rock-paper-scissors. Nature (2002) 9.07
Communicable ulcerative colitis induced by T-bet deficiency in the innate immune system. Cell (2007) 8.42
How host-microbial interactions shape the nutrient environment of the mammalian intestine. Annu Rev Nutr (2002) 8.31
Molecular analysis of the bacterial microbiota in the human stomach. Proc Natl Acad Sci U S A (2006) 7.77
The inner of the two Muc2 mucin-dependent mucus layers in colon is devoid of bacteria. Proc Natl Acad Sci U S A (2008) 7.43
Factors influencing the composition of the intestinal microbiota in early infancy. Pediatrics (2006) 7.40
Opinion: Re-evaluating prokaryotic species. Nat Rev Microbiol (2005) 7.19
Epithelial NEMO links innate immunity to chronic intestinal inflammation. Nature (2007) 7.17
Metagenomic analyses of an uncultured viral community from human feces. J Bacteriol (2003) 6.65
Symbiotic gut microbes modulate human metabolic phenotypes. Proc Natl Acad Sci U S A (2008) 6.42
Social evolution theory for microorganisms. Nat Rev Microbiol (2006) 6.41
Infectious history. Science (2000) 6.09
Bile salt biotransformations by human intestinal bacteria. J Lipid Res (2005) 6.00
The microbial pan-genome. Curr Opin Genet Dev (2005) 5.93
Evolution of symbiotic bacteria in the distal human intestine. PLoS Biol (2007) 5.79
Paneth cells directly sense gut commensals and maintain homeostasis at the intestinal host-microbial interface. Proc Natl Acad Sci U S A (2008) 5.78
Host-mediated inflammation disrupts the intestinal microbiota and promotes the overgrowth of Enterobacteriaceae. Cell Host Microbe (2007) 5.56
Automated approach for ribosomal intergenic spacer analysis of microbial diversity and its application to freshwater bacterial communities. Appl Environ Microbiol (1999) 5.39
Mucosal glycan foraging enhances fitness and transmission of a saccharolytic human gut bacterial symbiont. Cell Host Microbe (2008) 5.39
Gut microorganisms, mammalian metabolism and personalized health care. Nat Rev Microbiol (2005) 5.35
Metabolic profiling reveals a contribution of gut microbiota to fatty liver phenotype in insulin-resistant mice. Proc Natl Acad Sci U S A (2006) 5.19
Classification of methanogenic bacteria by 16S ribosomal RNA characterization. Proc Natl Acad Sci U S A (1977) 5.09
A humanized gnotobiotic mouse model of host-archaeal-bacterial mutualism. Proc Natl Acad Sci U S A (2006) 5.04
Species divergence and the measurement of microbial diversity. FEMS Microbiol Rev (2008) 4.97
Microbiology in the post-genomic era. Nat Rev Microbiol (2008) 4.88
High-density universal 16S rRNA microarray analysis reveals broader diversity than typical clone library when sampling the environment. Microb Ecol (2007) 4.81
Epithelial-cell-intrinsic IKK-beta expression regulates intestinal immune homeostasis. Nature (2007) 4.68
Microbes in gastrointestinal health and disease. Gastroenterology (2008) 4.65
Development of an extensive set of 16S rDNA-targeted primers for quantification of pathogenic and indigenous bacteria in faecal samples by real-time PCR. J Appl Microbiol (2004) 4.53
The role of ecological theory in microbial ecology. Nat Rev Microbiol (2007) 4.50
Communication in bacteria: an ecological and evolutionary perspective. Nat Rev Microbiol (2006) 4.44
Genomic and metabolic studies of the impact of probiotics on a model gut symbiont and host. PLoS Biol (2006) 4.27
Deletion of TLR5 results in spontaneous colitis in mice. J Clin Invest (2007) 4.18
High-throughput diversity and functionality analysis of the gastrointestinal tract microbiota. Gut (2008) 4.10
Local administration of antisense phosphorothioate oligonucleotides to the p65 subunit of NF-kappa B abrogates established experimental colitis in mice. Nat Med (1996) 4.09
Cultivating the uncultured. Proc Natl Acad Sci U S A (2002) 4.03
Molecular eco-systems biology: towards an understanding of community function. Nat Rev Microbiol (2008) 3.95
Intestinal alkaline phosphatase detoxifies lipopolysaccharide and prevents inflammation in zebrafish in response to the gut microbiota. Cell Host Microbe (2007) 3.88
The interaction between bacteria and bile. FEMS Microbiol Rev (2005) 3.86
DGGE/TGGE a method for identifying genes from natural ecosystems. Curr Opin Microbiol (1999) 3.71
Fecal microflora in healthy infants born by different methods of delivery: permanent changes in intestinal flora after cesarean delivery. J Pediatr Gastroenterol Nutr (1999) 3.56
Use of 16S rRNA gene-targeted group-specific primers for real-time PCR analysis of predominant bacteria in human feces. Appl Environ Microbiol (2004) 3.51
The surprisingly diverse ways that prokaryotes move. Nat Rev Microbiol (2008) 3.50
Toll-like receptors activate innate and adaptive immunity by using dendritic cell-intrinsic and -extrinsic mechanisms. Immunity (2008) 3.48
Shotgun metaproteomics of the human distal gut microbiota. ISME J (2008) 3.43
Oligonucleotide microarray for 16S rRNA gene-based detection of all recognized lineages of sulfate-reducing prokaryotes in the environment. Appl Environ Microbiol (2002) 3.26
Microbial biogeography: from taxonomy to traits. Science (2008) 3.22
Assembly of the human intestinal microbiota. Trends Ecol Evol (2006) 3.21
Microbial cell individuality and the underlying sources of heterogeneity. Nat Rev Microbiol (2006) 3.18
Human symbionts use a host-like pathway for surface fucosylation. Science (2005) 3.14
Gastrointestinal microbiology enters the metagenomics era. Curr Opin Gastroenterol (2008) 3.08
Evolution of species interactions in a biofilm community. Nature (2007) 3.01
Terminal restriction fragment length polymorphism (T-RFLP): an emerging method for characterizing diversity among homologous populations of amplification products. Curr Opin Microbiol (1999) 2.95
A synthetic Escherichia coli predator-prey ecosystem. Mol Syst Biol (2008) 2.92
'Everything is everywhere, but, the environment selects'; what did Baas Becking and Beijerinck really say? Environ Microbiol (2006) 2.79
Genomic and metabolic adaptations of Methanobrevibacter smithii to the human gut. Proc Natl Acad Sci U S A (2007) 2.79
Gut microbiota and its possible relationship with obesity. Mayo Clin Proc (2008) 2.63
Gut microbiota: a potential new territory for drug targeting. Nat Rev Drug Discov (2008) 2.59
Functional genomic and metabolic studies of the adaptations of a prominent adult human gut symbiont, Bacteroides thetaiotaomicron, to the suckling period. J Biol Chem (2006) 2.43
Defined spatial structure stabilizes a synthetic multispecies bacterial community. Proc Natl Acad Sci U S A (2008) 2.42
Living on a surface: swarming and biofilm formation. Trends Microbiol (2008) 2.37
The convergence of carbohydrate active gene repertoires in human gut microbes. Proc Natl Acad Sci U S A (2008) 2.33
Design and evaluation of PCR primers to amplify bacterial 16S ribosomal DNA fragments used for community fingerprinting. J Microbiol Methods (2001) 2.27
The Bacillus subtilis quorum-sensing molecule CSF contributes to intestinal homeostasis via OCTN2, a host cell membrane transporter. Cell Host Microbe (2007) 2.26
Rules of engagement: interspecies interactions that regulate microbial communities. Annu Rev Microbiol (2008) 2.22
Systemic multicompartmental effects of the gut microbiome on mouse metabolic phenotypes. Mol Syst Biol (2008) 2.17
Major viral impact on the functioning of benthic deep-sea ecosystems. Nature (2008) 2.11
Contributions of microbes in vertebrate gastrointestinal tract to production and conservation of nutrients. Physiol Rev (1998) 2.03