Published in J Mol Biol on June 16, 2009
Coordinated destruction of cellular messages in translation complexes by the gammaherpesvirus host shutoff factor and the mammalian exonuclease Xrn1. PLoS Pathog (2011) 1.21
Sequence, structure and functional diversity of PD-(D/E)XK phosphodiesterase superfamily. Nucleic Acids Res (2012) 1.18
Crystal structures of lambda exonuclease in complex with DNA suggest an electrostatic ratchet mechanism for processivity. Proc Natl Acad Sci U S A (2011) 1.08
Emerging roles for RNA degradation in viral replication and antiviral defense. Virology (2015) 1.08
Dxo1 is a new type of eukaryotic enzyme with both decapping and 5'-3' exoribonuclease activity. Nat Struct Mol Biol (2012) 1.08
Global mRNA degradation during lytic gammaherpesvirus infection contributes to establishment of viral latency. PLoS Pathog (2011) 0.97
Crystal structure of a KSHV-SOX-DNA complex: insights into the molecular mechanisms underlying DNase activity and host shutoff. Nucleic Acids Res (2011) 0.95
Immune responses to Epstein-Barr virus: molecular interactions in the virus evasion of CD8+ T cell immunity. Microbes Infect (2010) 0.94
Deep sequencing reveals direct targets of gammaherpesvirus-induced mRNA decay and suggests that multiple mechanisms govern cellular transcript escape. PLoS One (2011) 0.93
Murine gammaherpesvirus 68 infection protects lupus-prone mice from the development of autoimmunity. Proc Natl Acad Sci U S A (2012) 0.91
Interplay between viruses and host mRNA degradation. Biochim Biophys Acta (2012) 0.90
Selective Degradation of Host RNA Polymerase II Transcripts by Influenza A Virus PA-X Host Shutoff Protein. PLoS Pathog (2016) 0.89
An amphioxus RAG1-like DNA fragment encodes a functional central domain of vertebrate core RAG1. Proc Natl Acad Sci U S A (2013) 0.89
RalR (a DNase) and RalA (a small RNA) form a type I toxin-antitoxin system in Escherichia coli. Nucleic Acids Res (2014) 0.88
Mitochondrial nucleases ENDOG and EXOG participate in mitochondrial DNA depletion initiated by herpes simplex virus 1 UL12.5. J Virol (2013) 0.87
The "Bridge" in the Epstein-Barr virus alkaline exonuclease protein BGLF5 contributes to shutoff activity during productive infection. J Virol (2012) 0.86
Strategies for viral RNA stability: live long and prosper. Trends Genet (2011) 0.85
Immune escape of γ-herpesviruses from adaptive immunity. Rev Med Virol (2014) 0.84
Herpesviruses placating the unwilling host: manipulation of the MHC class II antigen presentation pathway. Viruses (2012) 0.83
Initiation of lytic DNA replication in Epstein-Barr virus: search for a common family mechanism. Future Virol (2010) 0.82
Cooperation between Epstein-Barr virus immune evasion proteins spreads protection from CD8+ T cell recognition across all three phases of the lytic cycle. PLoS Pathog (2014) 0.82
The UL12 protein of herpes simplex virus 1 is regulated by tyrosine phosphorylation. J Virol (2014) 0.82
Shutoff of Host Gene Expression in Influenza A Virus and Herpesviruses: Similar Mechanisms and Common Themes. Viruses (2016) 0.81
Structural and functional insight into the mechanism of an alkaline exonuclease from Laribacter hongkongensis. Nucleic Acids Res (2011) 0.81
Functional characterization of an alkaline exonuclease and single strand annealing protein from the SXT genetic element of Vibrio cholerae. BMC Mol Biol (2011) 0.79
Virus-induced NETs--critical component of host defense or pathogenic mediator? PLoS Pathog (2015) 0.79
Structural modelling and mutagenesis of human cytomegalovirus alkaline nuclease UL98. J Gen Virol (2011) 0.79
Diverse virus-host interactions influence RNA-based regulation during γ-herpesvirus infection. Curr Opin Microbiol (2012) 0.76
KSHV SOX mediated host shutoff: the molecular mechanism underlying mRNA transcript processing. Nucleic Acids Res (2017) 0.75
Diffraction cartography: applying microbeams to macromolecular crystallography sample evaluation and data collection. Acta Crystallogr D Biol Crystallogr (2010) 2.20
Insights into egg coat assembly and egg-sperm interaction from the X-ray structure of full-length ZP3. Cell (2010) 1.91
Host shutoff during productive Epstein-Barr virus infection is mediated by BGLF5 and may contribute to immune evasion. Proc Natl Acad Sci U S A (2007) 1.82
Molecular basis for amyloid-beta polymorphism. Proc Natl Acad Sci U S A (2011) 1.76
MxCuBE: a synchrotron beamline control environment customized for macromolecular crystallography experiments. J Synchrotron Radiat (2010) 1.71
A CD8+ T cell immune evasion protein specific to Epstein-Barr virus and its close relatives in Old World primates. J Exp Med (2007) 1.70
Cowpox virus inhibits the transporter associated with antigen processing to evade T cell recognition. Cell Host Microbe (2009) 1.47
Varicelloviruses avoid T cell recognition by UL49.5-mediated inactivation of the transporter associated with antigen processing. Proc Natl Acad Sci U S A (2005) 1.36
The Epstein-Barr virus G-protein-coupled receptor contributes to immune evasion by targeting MHC class I molecules for degradation. PLoS Pathog (2009) 1.31
The E3 ubiquitin ligases Hrd1 and gp78 bind to and promote cholera toxin retro-translocation. Mol Biol Cell (2009) 1.29
The DNase of gammaherpesviruses impairs recognition by virus-specific CD8+ T cells through an additional host shutoff function. J Virol (2007) 1.29
Expression, crystallization and X-ray data collection from microcrystals of the extracellular domain of the human inhibitory receptor expressed on myeloid cells IREM-1. Acta Crystallogr Sect F Struct Biol Cryst Commun (2007) 1.27
Viral evasion of T cell immunity: ancient mechanisms offering new applications. Curr Opin Immunol (2010) 1.24
Ubiquitination of MHC class I heavy chains is essential for dislocation by human cytomegalovirus-encoded US2 but not US11. J Biol Chem (2006) 1.23
Structure of the vesicular stomatitis virus N⁰-P complex. PLoS Pathog (2011) 1.20
Specific targeting of the EBV lytic phase protein BNLF2a to the transporter associated with antigen processing results in impairment of HLA class I-restricted antigen presentation. J Immunol (2009) 1.17
Ab initio structure determination and functional characterization of CBM36; a new family of calcium-dependent carbohydrate binding modules. Structure (2004) 1.15
Crystal structure of Spa40, the specificity switch for the Shigella flexneri type III secretion system. Mol Microbiol (2008) 1.12
Stage-specific inhibition of MHC class I presentation by the Epstein-Barr virus BNLF2a protein during virus lytic cycle. PLoS Pathog (2009) 1.11
Interaction of the C-terminal domains of sendai virus N and P proteins: comparison of polymerase-nucleocapsid interactions within the paramyxovirus family. J Virol (2007) 1.11
Reduced human leukocyte antigen expression in advanced-stage Ewing sarcoma: implications for immune recognition. J Pathol (2009) 1.09
Varicellovirus UL 49.5 proteins differentially affect the function of the transporter associated with antigen processing, TAP. PLoS Pathog (2008) 1.08
Structure and dynamics of the nucleocapsid-binding domain of the Sendai virus phosphoprotein in solution. Virology (2004) 1.06
Crystal structure of levansucrase from the Gram-negative bacterium Gluconacetobacter diazotrophicus. Biochem J (2005) 1.05
Structure of the Epstein-Barr virus oncogene BARF1. J Mol Biol (2006) 1.03
EBV lytic-phase protein BGLF5 contributes to TLR9 downregulation during productive infection. J Immunol (2010) 1.01
The crystal structure of the Epstein-Barr virus protease shows rearrangement of the processed C terminus. J Mol Biol (2002) 1.00
MHC class I molecules are preferentially ubiquitinated on endoplasmic reticulum luminal residues during HRD1 ubiquitin E3 ligase-mediated dislocation. Proc Natl Acad Sci U S A (2013) 0.97
The crystal structure of the extracellular domain of the inhibitor receptor expressed on myeloid cells IREM-1. J Mol Biol (2007) 0.95
EBV BILF1 evolved to downregulate cell surface display of a wide range of HLA class I molecules through their cytoplasmic tail. J Immunol (2013) 0.93
Inflammasomes and viruses: cellular defence versus viral offence. J Gen Virol (2012) 0.93
The monomeric dUTPase from Epstein-Barr virus mimics trimeric dUTPases. Structure (2005) 0.93
CD200 receptor controls sex-specific TLR7 responses to viral infection. PLoS Pathog (2012) 0.92
Low-resolution structure of vaccinia virus DNA replication machinery. J Virol (2012) 0.92
EBV protein BNLF2a exploits host tail-anchored protein integration machinery to inhibit TAP. J Immunol (2011) 0.91
New insights on the role of the gamma-herpesvirus uracil-DNA glycosylase leucine loop revealed by the structure of the Epstein-Barr virus enzyme in complex with an inhibitor protein. J Mol Biol (2006) 0.90
Crystal structure at 1.1 Angstroms resolution of an insect myrosinase from Brevicoryne brassicae shows its close relationship to beta-glucosidases. Insect Biochem Mol Biol (2005) 0.90
Inhibition of mouse TAP by immune evasion molecules encoded by non-murine herpesviruses. Mol Immunol (2011) 0.89
Structure of RavA MoxR AAA+ protein reveals the design principles of a molecular cage modulating the inducible lysine decarboxylase activity. Proc Natl Acad Sci U S A (2010) 0.89
The glucosinolate-myrosinase system. New insights into enzyme-substrate interactions by use of simplified inhibitors. Org Biomol Chem (2005) 0.89
Structural genomics of the Epstein-Barr virus. Acta Crystallogr D Biol Crystallogr (2006) 0.89
The varicellovirus UL49.5 protein blocks the transporter associated with antigen processing (TAP) by inhibiting essential conformational transitions in the 6+6 transmembrane TAP core complex. J Immunol (2008) 0.88
Adenovirus-specific CD4+ T cell clones recognizing endogenous antigen inhibit viral replication in vitro through cognate interaction. J Immunol (2006) 0.87
Herpesvirus interference with major histocompatibility complex class II-restricted T-cell activation. J Virol (2006) 0.87
Allosteric competitive inactivation of hematopoietic CSF-1 signaling by the viral decoy receptor BARF1. Nat Struct Mol Biol (2012) 0.86
The "Bridge" in the Epstein-Barr virus alkaline exonuclease protein BGLF5 contributes to shutoff activity during productive infection. J Virol (2012) 0.86
The capacity of UL49.5 proteins to inhibit TAP is widely distributed among members of the genus Varicellovirus. J Virol (2010) 0.85
Exploiting human herpesvirus immune evasion for therapeutic gain: potential and pitfalls. Immunol Cell Biol (2011) 0.84
Alternative Ii-independent antigen-processing pathway in leukemic blasts involves TAP-dependent peptide loading of HLA class II complexes. Cancer Immunol Immunother (2010) 0.84
Atomic resolution description of the interaction between the nucleoprotein and phosphoprotein of Hendra virus. PLoS Pathog (2013) 0.83
Viral interference with antigen presentation: trapping TAP. Mol Immunol (2012) 0.83
Hiding lipid presentation: viral interference with CD1d-restricted invariant natural killer T (iNKT) cell activation. Viruses (2012) 0.83
Structuring detergents for extracting and stabilizing functional membrane proteins. PLoS One (2011) 0.82
Epstein-Barr virus-encoded BARF1 protein is a decoy receptor for macrophage colony stimulating factor and interferes with macrophage differentiation and activation. Viral Immunol (2012) 0.82
Identification of new interacting partners of the shuttling protein ubinuclein (Ubn-1). Exp Cell Res (2012) 0.82
The structural basis for the integrity of adenovirus Ad3 dodecahedron. PLoS One (2012) 0.82
TAP-inhibiting proteins US6, ICP47 and UL49.5 differentially affect minor and major histocompatibility antigen-specific recognition by cytotoxic T lymphocytes. Int Immunol (2007) 0.81
The nested open reading frame in the Epstein-Barr virus nuclear antigen-1 mRNA encodes a protein capable of inhibiting antigen presentation in cis. Mol Immunol (2007) 0.81
Structural and functional analysis of the TAP-inhibiting UL49.5 proteins of varicelloviruses. Mol Immunol (2011) 0.81
A micromolar O-sulfated thiohydroximate inhibitor bound to plant myrosinase. Acta Crystallogr Sect F Struct Biol Cryst Commun (2010) 0.78
The flexible motif V of Epstein-Barr virus deoxyuridine 5'-triphosphate pyrophosphatase is essential for catalysis. J Biol Chem (2009) 0.78
Epstein-Barr virus isolates retain their capacity to evade T cell immunity through BNLF2a despite extensive sequence variation. J Virol (2011) 0.77
Structural and functional characterization of the single-chain Fv fragment from a unique HCV E1E2-specific monoclonal antibody. FEBS Lett (2013) 0.77
Crystallization and preliminary X-ray diffraction analysis of levansucrase (LsdA) from Gluconacetobacter diazotrophicus SRT4. Acta Crystallogr D Biol Crystallogr (2003) 0.77
Structure of the C-terminal domain of lettuce necrotic yellows virus phosphoprotein. J Virol (2013) 0.76
Manipulation of the immune response by Epstein-Barr virus and Kaposi's sarcoma-associated herpesvirus: consequences for tumor development. Semin Cancer Biol (2008) 0.76
Inhibition of Epstein-Barr virus replication by small interfering RNA targeting the Epstein-Barr virus protease gene. Antivir Ther (2009) 0.76
Fast intracrystalline hydration of beta-chitin revealed by combined microdrop generation and on-line synchrotron radiation microdiffraction. Biomacromolecules (2003) 0.75
Interaction of Ubinuclein-1, a nuclear and adhesion junction protein, with the 14-3-3 epsilon protein in epithelial cells: implication of the PKA pathway. Eur J Cell Biol (2013) 0.75
New asymmetric approach to natural pyrrolizidines: synthesis of (+)-amphorogynine A, (+)-amphorogynine D, and (+)-retronecine. J Org Chem (2005) 0.75
Evaluation of viral interference with MHC class I-restricted antigen processing and presentation using a flow cytometry-based approach. Methods Mol Biol (2013) 0.75
Kinetics, inhibition and oligomerization of Epstein-Barr virus protease. FEBS Lett (2006) 0.75
Nanostructuration of phenylenevinylenediimide-bridged silsesquioxane: from electroluminescent molecular J-aggregates to photoresponsive polymeric H-aggregates. J Am Chem Soc (2006) 0.75
Comprehensive analysis of fragment orbital interactions to build highly π-conjugated thienylene-substituted phenylene oligomers. Chemistry (2013) 0.75
A disymmetric terpyridine based ligand for the formation of luminescent di-aquo lanthanide complexes. Dalton Trans (2007) 0.75