Published in Am J Clin Nutr on June 24, 2009
Genetic sensitivity to the environment: the case of the serotonin transporter gene and its implications for studying complex diseases and traits. Am J Psychiatry (2010) 6.15
Overexpression of Fto leads to increased food intake and results in obesity. Nat Genet (2010) 4.37
Physical activity attenuates the influence of FTO variants on obesity risk: a meta-analysis of 218,166 adults and 19,268 children. PLoS Med (2011) 3.94
Physical activity attenuates the genetic predisposition to obesity in 20,000 men and women from EPIC-Norfolk prospective population study. PLoS Med (2010) 2.25
Lack of exercise is a major cause of chronic diseases. Compr Physiol (2012) 2.19
A commonly carried allele of the obesity-related FTO gene is associated with reduced brain volume in the healthy elderly. Proc Natl Acad Sci U S A (2010) 2.12
The genetics of obesity: FTO leads the way. Trends Genet (2010) 1.90
The FTO gene rs9939609 obesity-risk allele and loss of control over eating. Am J Clin Nutr (2009) 1.88
FTO, type 2 diabetes, and weight gain throughout adult life: a meta-analysis of 41,504 subjects from the Scandinavian HUNT, MDC, and MPP studies. Diabetes (2011) 1.75
The bigger picture of FTO: the first GWAS-identified obesity gene. Nat Rev Endocrinol (2013) 1.73
Television watching, leisure time physical activity, and the genetic predisposition in relation to body mass index in women and men. Circulation (2012) 1.33
Adult obesity susceptibility variants are associated with greater childhood weight gain and a faster tempo of growth: the 1946 British Birth Cohort Study. Am J Clin Nutr (2012) 1.26
A high intake of saturated fatty acids strengthens the association between the fat mass and obesity-associated gene and BMI. J Nutr (2011) 1.20
FTO genotype and adiposity in children: physical activity levels influence the effect of the risk genotype in adolescent males. Eur J Hum Genet (2010) 1.14
Nutrigenetics and nutrigenomics: viewpoints on the current status and applications in nutrition research and practice. J Nutrigenet Nutrigenomics (2011) 1.12
Increasing genetic variance of body mass index during the Swedish obesity epidemic. PLoS One (2011) 1.10
Association between the APOA2 promoter polymorphism and body weight in Mediterranean and Asian populations: replication of a gene-saturated fat interaction. Int J Obes (Lond) (2010) 1.08
Life-course analysis of a fat mass and obesity-associated (FTO) gene variant and body mass index in the Northern Finland Birth Cohort 1966 using structural equation modeling. Am J Epidemiol (2010) 1.02
Associations of FTO and MC4R Variants with Obesity Traits in Indians and the Role of Rural/Urban Environment as a Possible Effect Modifier. J Obes (2011) 1.02
Increased genetic variance of BMI with a higher prevalence of obesity. PLoS One (2011) 1.00
Beyond the fourth wave of genome-wide obesity association studies. Nutr Diabetes (2012) 0.98
Interaction of FTO and physical activity level on adiposity in African-American and European-American adults: the ARIC study. Obesity (Silver Spring) (2011) 0.97
Scientific decision making, policy decisions, and the obesity pandemic. Mayo Clin Proc (2013) 0.95
Evaluation of common genetic variants identified by GWAS for early onset and morbid obesity in population-based samples. Int J Obes (Lond) (2012) 0.95
Quantile-specific penetrance of genes affecting lipoproteins, adiposity and height. PLoS One (2012) 0.93
The acute and residual effect of a single exercise session on meal glucose tolerance in sedentary young adults. J Nutr Metab (2012) 0.92
Moderate to vigorous physical activity interactions with genetic variants and body mass index in a large US ethnically diverse cohort. Pediatr Obes (2013) 0.92
Common genetic variants and central adiposity among Asian-Indians. Obesity (Silver Spring) (2011) 0.91
Detailed analysis of variants in FTO in association with body composition in a cohort of 70-year-olds suggests a weakened effect among elderly. PLoS One (2011) 0.91
Attenuating effect of vigorous physical activity on the risk for inherited obesity: a study of 47,691 runners. PLoS One (2012) 0.89
The complex interplay of genetic and lifestyle risk factors in type 2 diabetes: an overview. Scientifica (Cairo) (2012) 0.89
Associations of genetic risk score with obesity and related traits and the modifying effect of physical activity in a Chinese Han population. PLoS One (2014) 0.83
Effects of sitting time associated with media consumption on physical activity patterns and daily energy expenditure of Saudi school students. J Phys Ther Sci (2015) 0.82
Primary weight maintenance: an observational study exploring candidate variables for intervention. Nutr J (2013) 0.82
Screen time behaviours may interact with obesity genes, independent of physical activity, to influence adolescent BMI in an ethnically diverse cohort. Pediatr Obes (2013) 0.82
Multiple novel gene-by-environment interactions modify the effect of FTO variants on body mass index. Nat Commun (2016) 0.82
Genomic insights into early-onset obesity. Genome Med (2010) 0.81
Modification of genetic influences on adiposity between 36 and 63 years of age by physical activity and smoking in the 1946 British Birth Cohort Study. Nutr Diabetes (2014) 0.81
Birth weight is associated with body composition in a multiethnic pediatric cohort. Open Obes J (2011) 0.81
Gender-specific associations between ADIPOQ gene polymorphisms and adiponectin levels and obesity in the Jackson Heart Study cohort. BMC Med Genet (2015) 0.80
Dose-response relationship between walking and the attenuation of inherited weight. Prev Med (2011) 0.79
Effect of FTO Gene and Physical Activity Interaction on Trunk Fat Percentage Among the Newfoundland Population. Genet Epigenet (2014) 0.79
Genome-wide physical activity interactions in adiposity - A meta-analysis of 200,452 adults. PLoS Genet (2017) 0.78
Is genetic testing of value in predicting and treating obesity? N C Med J (2013) 0.78
Genetic variants influencing effectiveness of exercise training programmes in obesity - an overview of human studies. Biol Sport (2016) 0.78
Clinical applications of epigenetics in cardiovascular disease: the long road ahead. Transl Res (2014) 0.78
Does the FTO gene interact with the socioeconomic status on the obesity development among young European children? Results from the IDEFICS study. Int J Obes (Lond) (2014) 0.78
Changes in Physical Activity Following a Genetic-Based Internet-Delivered Personalized Intervention: Randomized Controlled Trial (Food4Me). J Med Internet Res (2016) 0.78
Association Study of Fat-mass and Obesity-associated Gene and Body Mass Index in Japanese Patients with Schizophrenia and Healthy Subjects. Clin Psychopharmacol Neurosci (2012) 0.77
Impact of obesity-related genes in Spanish population. BMC Genet (2013) 0.77
In reply—Maternal, paternal, and societal efforts are needed to "cure" childhood obesity. Mayo Clin Proc (2015) 0.77
Behavioral and Environmental Modification of the Genetic Influence on Body Mass Index: A Twin Study. Behav Genet (2015) 0.76
Genotype by energy expenditure interaction and body composition traits: The Portuguese Healthy Family Study. Biomed Res Int (2014) 0.75
Assessing gene-environment interaction effects of FTO, MC4R and lifestyle factors on obesity using an extreme phenotype sampling design: Results from the HUNT study. PLoS One (2017) 0.75
FTO association and interaction with time spent sitting. Int J Obes (Lond) (2015) 0.75
Interaction between FTO gene variants and lifestyle factors on metabolic traits in an Asian Indian population. Nutr Metab (Lond) (2016) 0.75
The FTO rs9939609 and LEPR rs1137101 mothers-newborns gene polymorphisms and maternal fat mass index effects on anthropometric characteristics in newborns: A cross-sectional study on mothers-newborns gene polymorphisms-The FTO-LEPR Study (STROBE-compliant article). Medicine (Baltimore) (2016) 0.75
Association of Fat Mass and Obesity-associated Gene Variant with Lifestyle Factors and Body Fat in Indian Children. Indian J Endocrinol Metab (2017) 0.75
Attenuated inheritance of body weight by running in monozygotic twins. Med Sci Sports Exerc (2012) 0.75
The effects of parental education on exercise behavior in childhood and youth: a study in Dutch and Finnish twins. Scand J Med Sci Sports (2016) 0.75
No seasonal variation in physical activity of Han Chinese living in Beijing. Int J Behav Nutr Phys Act (2017) 0.75
International physical activity questionnaire: 12-country reliability and validity. Med Sci Sports Exerc (2003) 47.83
A common variant in the FTO gene is associated with body mass index and predisposes to childhood and adult obesity. Science (2007) 37.88
Meta-analysis of genome-wide association data and large-scale replication identifies additional susceptibility loci for type 2 diabetes. Nat Genet (2008) 35.06
Biological, clinical and population relevance of 95 loci for blood lipids. Nature (2010) 28.21
Association analyses of 249,796 individuals reveal 18 new loci associated with body mass index. Nat Genet (2010) 23.08
Six new loci associated with body mass index highlight a neuronal influence on body weight regulation. Nat Genet (2008) 22.35
Hundreds of variants clustered in genomic loci and biological pathways affect human height. Nature (2010) 20.01
New genetic loci implicated in fasting glucose homeostasis and their impact on type 2 diabetes risk. Nat Genet (2010) 17.89
Twelve type 2 diabetes susceptibility loci identified through large-scale association analysis. Nat Genet (2010) 16.96
Genome-wide association analysis identifies 20 loci that influence adult height. Nat Genet (2008) 16.92
Common variants near MC4R are associated with fat mass, weight and risk of obesity. Nat Genet (2008) 15.94
Large-scale association analysis identifies 13 new susceptibility loci for coronary artery disease. Nat Genet (2011) 13.25
Genetic variants in novel pathways influence blood pressure and cardiovascular disease risk. Nature (2011) 13.25
Association of dietary, circulating, and supplement fatty acids with coronary risk: a systematic review and meta-analysis. Ann Intern Med (2014) 12.79
Genome-wide association study identifies eight loci associated with blood pressure. Nat Genet (2009) 12.44
Global physical activity levels: surveillance progress, pitfalls, and prospects. Lancet (2012) 12.05
Large-scale association analysis provides insights into the genetic architecture and pathophysiology of type 2 diabetes. Nat Genet (2012) 11.09
Variants in MTNR1B influence fasting glucose levels. Nat Genet (2008) 10.85
Physical activity and clustered cardiovascular risk in children: a cross-sectional study (The European Youth Heart Study). Lancet (2006) 8.95
Common genetic determinants of vitamin D insufficiency: a genome-wide association study. Lancet (2010) 8.89
Meta-analysis and imputation refines the association of 15q25 with smoking quantity. Nat Genet (2010) 8.55
Correlates of physical activity: why are some people physically active and others not? Lancet (2012) 8.19
Meta-analysis identifies 13 new loci associated with waist-hip ratio and reveals sexual dimorphism in the genetic basis of fat distribution. Nat Genet (2010) 7.94
Screening for type 2 diabetes and population mortality over 10 years (ADDITION-Cambridge): a cluster-randomised controlled trial. Lancet (2012) 6.81
Genetic variation in GIPR influences the glucose and insulin responses to an oral glucose challenge. Nat Genet (2010) 6.66
LDL-cholesterol concentrations: a genome-wide association study. Lancet (2008) 6.44
Moderate to vigorous physical activity and sedentary time and cardiometabolic risk factors in children and adolescents. JAMA (2012) 6.43
C-reactive protein, fibrinogen, and cardiovascular disease prediction. N Engl J Med (2012) 6.39
Triglycerides and the risk of coronary heart disease: 10,158 incident cases among 262,525 participants in 29 Western prospective studies. Circulation (2006) 6.17
The metabochip, a custom genotyping array for genetic studies of metabolic, cardiovascular, and anthropometric traits. PLoS Genet (2012) 6.15
Genome-wide association scan meta-analysis identifies three Loci influencing adiposity and fat distribution. PLoS Genet (2009) 5.81
Identification of 23 new prostate cancer susceptibility loci using the iCOGS custom genotyping array. Nat Genet (2013) 5.58
Genome-wide meta-analysis identifies 56 bone mineral density loci and reveals 14 loci associated with risk of fracture. Nat Genet (2012) 5.48
Loss-of-function mutations in APOC3, triglycerides, and coronary disease. N Engl J Med (2014) 5.47
Subclinical hypothyroidism and the risk of coronary heart disease and mortality. JAMA (2010) 5.20
The interleukin-6 receptor as a target for prevention of coronary heart disease: a mendelian randomisation analysis. Lancet (2012) 4.87
Large-scale association analyses identify new loci influencing glycemic traits and provide insight into the underlying biological pathways. Nat Genet (2012) 4.73