Published in Int J Radiat Biol on July 01, 2009
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Reduction of radiation-induced vascular nitrosative stress by the vitamin E analog γ-tocotrienol: evidence of a role for tetrahydrobiopterin. Int J Radiat Oncol Biol Phys (2010) 0.96
Pentoxifylline enhances the radioprotective properties of γ-tocotrienol: differential effects on the hematopoietic, gastrointestinal and vascular systems. Radiat Res (2010) 0.95
γ-Tocotrienol protects against mitochondrial dysfunction and renal cell death. J Pharmacol Exp Ther (2011) 0.94
Amelioration of radiation-induced hematopoietic and gastrointestinal damage by Ex-RAD(R) in mice. J Radiat Res (2012) 0.92
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Mechanism of radioprotection by δ-tocotrienol: pharmacokinetics, pharmacodynamics and modulation of signalling pathways. Br J Radiol (2012) 0.85
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Thrombomodulin contributes to gamma tocotrienol-mediated lethality protection and hematopoietic cell recovery in irradiated mice. PLoS One (2015) 0.85
Evaluation of the fullerene compound DF-1 as a radiation protector. Radiat Oncol (2010) 0.84
Progenitors mobilized by gamma-tocotrienol as an effective radiation countermeasure. PLoS One (2014) 0.82
A tocotrienol-enriched formulation protects against radiation-induced changes in cardiac mitochondria without modifying late cardiac function or structure. Radiat Res (2015) 0.82
Molecular dynamics guided design of tocoflexol: a new radioprotectant tocotrienol with enhanced bioavailability. Drug Dev Res (2013) 0.80
Novel strategies to ameliorate radiation injury: a possible role for tetrahydrobiopterin. Curr Drug Targets (2010) 0.79
Gamma-tocopherol-N,N-dimethylglycine ester as a potent post-irradiation mitigator against whole body X-irradiation-induced bone marrow death in mice. J Radiat Res (2013) 0.79
Vitamin E Analogs as Radiation Response Modifiers. Evid Based Complement Alternat Med (2015) 0.78
Synergistic radioprotection by gamma-tocotrienol and pentoxifylline: role of cAMP signaling. ISRN Radiol (2013) 0.77
Statistical analysis of survival data from radiation countermeasure experiments. Radiat Res (2012) 0.77
γ-Tocotrienol as a Promising Countermeasure for Acute Radiation Syndrome: Current Status. Int J Mol Sci (2016) 0.76
The Vitamin E Analog Gamma-Tocotrienol (GT3) Suppresses Radiation-Induced Cytogenetic Damage. Pharm Res (2016) 0.76
Establishment of Early Endpoints in Mouse Total-Body Irradiation Model. PLoS One (2016) 0.75
Detection of Acute Radiation Sickness: A Feasibility Study in Non-Human Primates Circulating miRNAs for Triage in Radiological Events. PLoS One (2016) 0.75
Synthesis of (2R,8' S,3' E)-δ-tocodienol, a tocoflexol family member designed to have a superior pharmacokinetic profile compared to δ-tocotrienol. Tetrahedron (2016) 0.75
Protection against Radiotherapy-Induced Toxicity. Antioxidants (Basel) (2016) 0.75
Development of Orally Administered γ-Tocotrienol (GT3) Nanoemulsion for Radioprotection. Int J Mol Sci (2016) 0.75
Gamma-Tocotrienol Modulates Radiation-Induced MicroRNA Expression in Mouse Spleen. Radiat Res (2016) 0.75
Rice Bran Metabolome Contains Amino Acids, Vitamins & Cofactors, and Phytochemicals with Medicinal and Nutritional Properties. Rice (N Y) (2017) 0.75
Tissue distribution of emulsified γ-tocotrienol and its long-term biological effects after subcutaneous administration. Lipids Health Dis (2014) 0.75
Protective effect of an antithyroid compound against γ-radiation-induced damage in human colon cancer cells. Radiat Environ Biophys (2014) 0.75
Impact of Abbreviated Filgrastim Schedule on Survival and Hematopoietic Recovery after Irradiation in Four Mouse Strains with Different Radiosensitivity. Radiat Res (2017) 0.75
Pharmacological Modulation of Radiation Damage. Does It Exist a Chance for Other Substances than Hematopoietic Growth Factors and Cytokines? Int J Mol Sci (2017) 0.75
Appraisal of biochemical classes of radioprotectors: evidence, current status and guidelines for future development. 3 Biotech (2017) 0.75
A genome-wide view of the spectrum of spontaneous mutations in yeast. Proc Natl Acad Sci U S A (2008) 5.90
Perspectives on cancer therapy-induced mucosal injury: pathogenesis, measurement, epidemiology, and consequences for patients. Cancer (2004) 3.83
Animal models for medical countermeasures to radiation exposure. Radiat Res (2010) 2.83
Models for evaluating agents intended for the prophylaxis, mitigation and treatment of radiation injuries. Report of an NCI Workshop, December 3-4, 2003. Radiat Res (2004) 2.33
Comparison of mortality rates in statin users versus nonstatin users in a United States veteran population. Am J Cardiol (2006) 2.19
Literature review and global consensus on management of acute radiation syndrome affecting nonhematopoietic organ systems. Disaster Med Public Health Prep (2011) 1.93
The radiotherapeutic injury--a complex 'wound'. Radiother Oncol (2002) 1.82
Involvement of heat shock factor 1 in statin-induced transcriptional upregulation of endothelial thrombomodulin. Circ Res (2008) 1.64
Pharmacological targeting of the thrombomodulin-activated protein C pathway mitigates radiation toxicity. Nat Med (2012) 1.58
Effects of radiation on the epidermal growth factor receptor pathway in the heart. Int J Radiat Biol (2013) 1.49
Normal tissue effects: reporting and analysis. Semin Radiat Oncol (2003) 1.44
Significance of endothelial dysfunction in the pathogenesis of early and delayed radiation enteropathy. World J Gastroenterol (2007) 1.42
Deficiency of microvascular thrombomodulin and up-regulation of protease-activated receptor-1 in irradiated rat intestine: possible link between endothelial dysfunction and chronic radiation fibrosis. Am J Pathol (2002) 1.39
The relationship between alcohol use and risk-taking sexual behaviors in a large behavioral study. Prev Med (2004) 1.37
gamma-Tocotrienol ameliorates intestinal radiation injury and reduces vascular oxidative stress after total-body irradiation by an HMG-CoA reductase-dependent mechanism. Radiat Res (2009) 1.32
Impact of renal transplantation on survival in end-stage renal disease patients with elevated body mass index. Kidney Int (2003) 1.32
Hyperbaric oxygen stimulates vasculogenic stem cell growth and differentiation in vivo. J Appl Physiol (1985) (2008) 1.30
Protection from adverse myocardial remodeling secondary to chronic volume overload in mast cell deficient rats. J Mol Cell Cardiol (2008) 1.27
Interlaboratory comparison of the dicentric chromosome assay for radiation biodosimetry in mass casualty events. Radiat Res (2008) 1.23
Decreasing the adverse effects of cancer therapy: National Cancer Institute guidance for the clinical development of radiation injury mitigators. Clin Cancer Res (2010) 1.22
Prostate-specific antigen versus prostate-specific antigen density as predictor of tumor volume, margin status, pathologic stage, and biochemical recurrence of prostate cancer. Urology (2005) 1.13
Nonfatal Suicidal Behaviors in U.S. Army Administrative Records, 2004-2009: Results from the Army Study to Assess Risk and Resilience in Servicemembers (Army STARRS). Psychiatry (2015) 1.11
Comparative expression profiling in primary and immortalized endothelial cells: changes in gene expression in response to hydroxy methylglutaryl-coenzyme A reductase inhibition. Blood Coagul Fibrinolysis (2006) 1.11
Comparative gene expression profiling in three primary human cell lines after treatment with a novel inhibitor of Rho kinase or atorvastatin. Blood Coagul Fibrinolysis (2008) 1.11
Prevention and treatment of functional and structural radiation injury in the rat heart by pentoxifylline and alpha-tocopherol. Int J Radiat Oncol Biol Phys (2008) 1.10
First global consensus for evidence-based management of the hematopoietic syndrome resulting from exposure to ionizing radiation. Disaster Med Public Health Prep (2011) 1.10
Defining pelvic-radiation disease for the survivorship era. Lancet Oncol (2010) 1.09
Hyperhomocysteinemia leads to pathological ventricular hypertrophy in normotensive rats. Am J Physiol Heart Circ Physiol (2003) 1.09
Statins increase thrombomodulin expression and function in human endothelial cells by a nitric oxide-dependent mechanism and counteract tumor necrosis factor alpha-induced thrombomodulin downregulation. Blood Coagul Fibrinolysis (2003) 1.07
Gamma-tocotrienol protects hematopoietic stem and progenitor cells in mice after total-body irradiation. Radiat Res (2010) 1.07
Development of a combined radiation and burn injury model. J Burn Care Res (2011) 1.07
Influence of mast cells on structural and functional manifestations of radiation-induced heart disease. Cancer Res (2005) 1.06
Radiation responses in skin and connective tissues: effect on wound healing and surgical outcome. Hernia (2006) 1.05
Alpha-tocopherol succinate protects mice from gamma-radiation by induction of granulocyte-colony stimulating factor. Int J Radiat Biol (2010) 1.05
Oral PEG 15-20 protects the intestine against radiation: role of lipid rafts. Am J Physiol Gastrointest Liver Physiol (2009) 1.04
The somatostatin analog SOM230 (pasireotide) ameliorates injury of the intestinal mucosa and increases survival after total-body irradiation by inhibiting exocrine pancreatic secretion. Radiat Res (2009) 1.02
Pharmacotherapy and the risk for community-acquired pneumonia. BMC Geriatr (2010) 1.01
Gastrointestinal mucositis. Semin Oncol Nurs (2004) 1.00
"Pelvic radiation disease": new understanding and new solutions for a new disease in the era of cancer survivorship. Scand J Gastroenterol (2010) 1.00
Simvastatin ameliorates radiation enteropathy development after localized, fractionated irradiation by a protein C-independent mechanism. Int J Radiat Oncol Biol Phys (2007) 0.99
Uses of proton pump inhibitors and hypomagnesemia. Pharmacoepidemiol Drug Saf (2012) 0.99
Lactate stimulates vasculogenic stem cells via the thioredoxin system and engages an autocrine activation loop involving hypoxia-inducible factor 1. Mol Cell Biol (2008) 0.98
Hematopoietic Recovery and Amelioration of Radiation-Induced Lethality by the Vitamin E Isoform δ-Tocotrienol. Radiat Res (2011) 0.98
Influence of sublethal total-body irradiation on immune cell populations in the intestinal mucosa. Radiat Res (2010) 0.97
Gamma-tocotrienol, a radiation prophylaxis agent, induces high levels of granulocyte colony-stimulating factor. Int Immunopharmacol (2012) 0.97
Nutritional approaches to radioprotection: vitamin E. Mil Med (2002) 0.96
Reduction of radiation-induced vascular nitrosative stress by the vitamin E analog γ-tocotrienol: evidence of a role for tetrahydrobiopterin. Int J Radiat Oncol Biol Phys (2010) 0.96
Induction of cytokines by radioprotective tocopherol analogs. Exp Mol Pathol (2006) 0.96
PARP1 is required for chromosomal translocations. Blood (2013) 0.96
IKKβ regulates the repair of DNA double-strand breaks induced by ionizing radiation in MCF-7 breast cancer cells. PLoS One (2011) 0.95
Preferential radiation sensitization of prostate cancer in nude mice by nutraceutical antioxidant gamma-tocotrienol. Life Sci (2006) 0.95
Pentoxifylline enhances the radioprotective properties of γ-tocotrienol: differential effects on the hematopoietic, gastrointestinal and vascular systems. Radiat Res (2010) 0.95
Correlations between serum monocyte chemotactic protein-1 levels, clinical prognostic factors, and HER-2/neu vaccine-related immunity in breast cancer patients. Clin Cancer Res (2006) 0.95
Hematological targets of radiation damage. Curr Drug Targets (2010) 0.95
A novel technique for image-guided local heart irradiation in the rat. Technol Cancer Res Treat (2013) 0.95
γ-Tocotrienol protects against mitochondrial dysfunction and renal cell death. J Pharmacol Exp Ther (2011) 0.94
Tocopherol succinate: a promising radiation countermeasure. Int Immunopharmacol (2009) 0.94
Human TSC2-null fibroblast-like cells induce hair follicle neogenesis and hamartoma morphogenesis. Nat Commun (2011) 0.93
HYOU1/Orp150 expression in breast cancer. Med Sci Monit (2007) 0.93
Cardiac inflammation after local irradiation is influenced by the kallikrein-kinin system. Cancer Res (2012) 0.93
Radiation protection by a new chemical entity, Ex-Rad: efficacy and mechanisms. Radiat Res (2009) 0.92
Amelioration of radiation-induced hematopoietic and gastrointestinal damage by Ex-RAD(R) in mice. J Radiat Res (2012) 0.92
Influence of mast cells on outcome after heterotopic cardiac transplantation in rats. Transpl Int (2007) 0.92
Local administration of interleukin-11 ameliorates intestinal radiation injury in rats. Cancer Res (2007) 0.92
Determination of sample sizes for demonstrating efficacy of radiation countermeasures. Biometrics (2009) 0.91
Up-regulation and activation of proteinase-activated receptor 2 in early and delayed radiation injury in the rat intestine: influence of biological activators of proteinase-activated receptor 2. Radiat Res (2003) 0.91
Hyperhomocysteinemia leads to adverse cardiac remodeling in hypertensive rats. Am J Physiol Heart Circ Physiol (2002) 0.91
Mechanisms underlying the radioprotective properties of γ-tocotrienol: comparative gene expression profiling in tocol-treated endothelial cells. Genes Nutr (2011) 0.90
Tocopherol succinate: modulation of antioxidant enzymes and oncogene expression, and hematopoietic recovery. Int J Radiat Oncol Biol Phys (2010) 0.90
Preclinical development of a bridging therapy for radiation casualties. Exp Hematol (2010) 0.90
The combined effect of age and basal follicle-stimulating hormone on the cost of a live birth at assisted reproductive technology. Fertil Steril (2007) 0.89
Clinical significance of increased gelatinolytic activity in the rectal mucosa during external beam radiation therapy of prostate cancer. Int J Radiat Oncol Biol Phys (2002) 0.89
Radiation-induced alterations in mitochondria of the rat heart. Radiat Res (2014) 0.88
5-AED enhances survival of irradiated mice in a G-CSF-dependent manner, stimulates innate immune cell function, reduces radiation-induced DNA damage and induces genes that modulate cell cycle progression and apoptosis. J Radiat Res (2012) 0.88
Bone marrow transplantation helps restore the intestinal mucosal barrier after total body irradiation in mice. Radiat Res (2014) 0.88
Short-term inhibition of ADP-induced platelet aggregation by clopidogrel ameliorates radiation-induced toxicity in rat small intestine. Thromb Haemost (2002) 0.87
Pharmacological induction of transforming growth factor-beta1 in rat models enhances radiation injury in the intestine and the heart. PLoS One (2013) 0.87
Novel drugs to ameliorate gastrointestinal normal tissue radiation toxicity in clinical practice: what is emerging from the laboratory? Curr Opin Support Palliat Care (2012) 0.87
Sublethal total body irradiation leads to early cerebellar damage and oxidative stress. Curr Neurovasc Res (2010) 0.86