Published in Br J Psychiatry on July 01, 2009
Gene ontology analysis of GWA study data sets provides insights into the biology of bipolar disorder. Am J Hum Genet (2009) 5.98
The Kraepelinian dichotomy - going, going... but still not gone. Br J Psychiatry (2010) 4.47
Psychosis genetics: modeling the relationship between schizophrenia, bipolar disorder, and mixed (or "schizoaffective") psychoses. Schizophr Bull (2009) 2.39
RBFOX1 regulates both splicing and transcriptional networks in human neuronal development. Hum Mol Genet (2012) 1.51
Sparse reduced-rank regression detects genetic associations with voxel-wise longitudinal phenotypes in Alzheimer's disease. Neuroimage (2011) 1.41
Genetic overlap between autism, schizophrenia and bipolar disorder. Genome Med (2009) 1.37
Copy number variants for schizophrenia and related psychotic disorders in Oceanic Palau: risk and transmission in extended pedigrees. Biol Psychiatry (2011) 1.25
Polygenic dissection of the bipolar phenotype. Br J Psychiatry (2011) 1.17
Homeodomain protein otp and activity-dependent splicing modulate neuronal adaptation to stress. Neuron (2012) 1.02
Genetic relationships between schizophrenia, bipolar disorder, and schizoaffective disorder. Schizophr Bull (2014) 1.01
Expression of GABAA α2-, β1- and ε-receptors are altered significantly in the lateral cerebellum of subjects with schizophrenia, major depression and bipolar disorder. Transl Psychiatry (2013) 0.98
The role of AUTS2 in neurodevelopment and human evolution. Trends Genet (2013) 0.97
Neurogenetics of aggressive behavior: studies in rodents. Curr Top Behav Neurosci (2014) 0.91
Orchestration of neurodevelopmental programs by RBFOX1: implications for autism spectrum disorder. Int Rev Neurobiol (2013) 0.91
Developmental expression mapping of a gene implicated in multiple neurodevelopmental disorders, A2bp1 (Fox1). Dev Neurosci (2011) 0.90
A twin study of schizoaffective-mania, schizoaffective-depression, and other psychotic syndromes. Am J Med Genet B Neuropsychiatr Genet (2011) 0.90
Possible functional links among brain- and skull-related genes selected in modern humans. Front Psychol (2015) 0.89
Role of the cytoplasmic isoform of RBFOX1/A2BP1 in establishing the architecture of the developing cerebral cortex. Mol Autism (2015) 0.88
Role of paliperidone extended-release in treatment of schizoaffective disorder. Neuropsychiatr Dis Treat (2010) 0.87
Intragenic deletion of RBFOX1 associated with neurodevelopmental/neuropsychiatric disorders and possibly other clinical presentations. Mol Cytogenet (2013) 0.85
IGENT: efficient entropy based algorithm for genome-wide gene-gene interaction analysis. BMC Med Genomics (2014) 0.85
Phenotypically distinct subtypes of psychosis accompany novel or rare variants in four different signaling genes. EBioMedicine (2016) 0.83
Genetic regulation of Nrxn1 [corrected] expression: an integrative cross-species analysis of schizophrenia candidate genes. Transl Psychiatry (2011) 0.83
Distinctive genetic activity pattern of the human dental pulp between deciduous and permanent teeth. PLoS One (2014) 0.82
Database of genetic studies of bipolar disorder. Psychiatr Genet (2011) 0.80
Genome-wide distribution of Auts2 binding localizes with active neurodevelopmental genes. Transl Psychiatry (2014) 0.78
FOX-2 dependent splicing of ataxin-2 transcript is affected by ataxin-1 overexpression. PLoS One (2012) 0.77
A genome-wide association study of antidepressant response in Koreans. Transl Psychiatry (2015) 0.77
Essential role of the nuclear isoform of RBFOX1, a candidate gene for autism spectrum disorders, in the brain development. Sci Rep (2016) 0.76
Genetic Consideration of Schizotypal Traits: A Review. Front Psychol (2016) 0.75
Identifying Potential Regions of Copy Number Variation for Bipolar Disorder. Microarrays (Basel) (2014) 0.75
A KCNJ6 gene polymorphism modulates theta oscillations during reward processing. Int J Psychophysiol (2016) 0.75
Loss-of-function of PTPR γ and ζ, observed in sporadic schizophrenia, causes brain region-specific deregulation of monoamine levels and altered behavior in mice. Psychopharmacology (Berl) (2016) 0.75
PLINK: a tool set for whole-genome association and population-based linkage analyses. Am J Hum Genet (2007) 209.92
Genome-wide association study of 14,000 cases of seven common diseases and 3,000 shared controls. Nature (2007) 144.95
Genomic control for association studies. Biometrics (1999) 64.39
Meta-analysis of genome-wide association data and large-scale replication identifies additional susceptibility loci for type 2 diabetes. Nat Genet (2008) 35.06
Genome-wide association studies for complex traits: consensus, uncertainty and challenges. Nat Rev Genet (2008) 30.94
Research diagnostic criteria: rationale and reliability. Arch Gen Psychiatry (1978) 15.32
Identification of loci associated with schizophrenia by genome-wide association and follow-up. Nat Genet (2008) 10.52
Estimation of significance thresholds for genomewide association scans. Genet Epidemiol (2008) 8.88
Establishment of diagnostic validity in psychiatric illness: its application to schizophrenia. Am J Psychiatry (1970) 8.51
A polydiagnostic application of operational criteria in studies of psychotic illness. Development and reliability of the OPCRIT system. Arch Gen Psychiatry (1991) 6.74
New links to the pathogenesis of Crohn disease provided by genome-wide association scans. Nat Rev Genet (2008) 4.35
A twin study of genetic relationships between psychotic symptoms. Am J Psychiatry (2002) 3.95
The structure of psychosis: latent class analysis of probands from the Roscommon Family Study. Arch Gen Psychiatry (1998) 3.61
Cytogenetic and molecular characterization of A2BP1/FOX1 as a candidate gene for autism. Am J Med Genet B Neuropsychiatr Genet (2007) 3.11
The de novo chromosome 16 translocations of two patients with abnormal phenotypes (mental retardation and epilepsy) disrupt the A2BP1 gene. J Hum Genet (2004) 2.89
Rethinking psychosis: the disadvantages of a dichotomous classification now outweigh the advantages. World Psychiatry (2007) 2.82
A family study of schizoaffective, bipolar I, bipolar II, unipolar, and normal control probands. Arch Gen Psychiatry (1982) 2.75
Continuity and discontinuity of affective disorders and schizophrenia. Results of a controlled family study. Arch Gen Psychiatry (1993) 2.71
Concurrent validity of the OPCRIT diagnostic system. Comparison of OPCRIT diagnoses with consensus best-estimate lifetime diagnoses. Br J Psychiatry (1996) 2.42
Strong genetic evidence for a selective influence of GABAA receptors on a component of the bipolar disorder phenotype. Mol Psychiatry (2008) 2.38
Do schizoaffective disorders exist at all? Acta Psychiatr Scand (2006) 1.79
Support for genetic variation in neuregulin 1 and susceptibility to schizophrenia. Mol Psychiatry (2003) 1.73
Genome-wide association studies in psychiatry: lessons from early studies of non-psychiatric and psychiatric phenotypes. Mol Psychiatry (2008) 1.60
Linkage analysis of psychosis in bipolar pedigrees suggests novel putative loci for bipolar disorder and shared susceptibility with schizophrenia. Mol Psychiatry (2004) 1.46
Suggestive linkage to chromosomal regions 13q31 and 22q12 in families with psychotic bipolar disorder. Am J Psychiatry (2003) 1.36
Schizoaffective disorder merges schizophrenia and bipolar disorders as one disease--there is no schizoaffective disorder. Curr Opin Psychiatry (2007) 1.31
Twin concordance for DSM-III schizophrenia. Scrutinizing the validity of the definition. Arch Gen Psychiatry (1987) 1.29
Familial rates of affective disorder. A report from the National Institute of Mental Health Collaborative Study. Arch Gen Psychiatry (1987) 1.22
Schizoaffective disorder: diagnostic issues and future recommendations. Bipolar Disord (2008) 1.19
Psychiatric diagnoses: the weak component of modern research. World Psychiatry (2007) 1.13
Schizoaffective disorder-- the reliability of its clinical diagnostic use. Acta Psychiatr Scand (2006) 1.04
Resemblance of psychotic symptoms and syndromes in affected sibling pairs from the Irish Study of High-Density Schizophrenia Families: evidence for possible etiologic heterogeneity. Am J Psychiatry (1997) 1.03
Further exploration of a latent class typology of schizophrenia. Schizophr Res (1996) 0.96
Schizoaffective psychoses: genetical clues to classification. Am J Med Genet (1995) 0.95
Five latent factors underlying schizophrenia: analysis and relationship to illnesses in relatives. Schizophr Bull (2004) 0.95
Genome-wide association study of 14,000 cases of seven common diseases and 3,000 shared controls. Nature (2007) 144.95
Meta-analysis of genome-wide association data and large-scale replication identifies additional susceptibility loci for type 2 diabetes. Nat Genet (2008) 35.06
The complete genome sequence of the gram-positive bacterium Bacillus subtilis. Nature (1997) 33.47
Genome-wide association defines more than 30 distinct susceptibility loci for Crohn's disease. Nat Genet (2008) 30.20
Effectiveness and efficiency of guideline dissemination and implementation strategies. Health Technol Assess (2004) 29.45
Origins and functional impact of copy number variation in the human genome. Nature (2009) 23.63
Six new loci associated with body mass index highlight a neuronal influence on body weight regulation. Nat Genet (2008) 22.35
Robust associations of four new chromosome regions from genome-wide analyses of type 1 diabetes. Nat Genet (2007) 19.04
Changing provider behavior: an overview of systematic reviews of interventions. Med Care (2001) 17.89
Genome-wide association analysis identifies 20 loci that influence adult height. Nat Genet (2008) 16.92
Common variants near MC4R are associated with fat mass, weight and risk of obesity. Nat Genet (2008) 15.94
The genome sequence of Schizosaccharomyces pombe. Nature (2002) 14.26
Sequence variants in the autophagy gene IRGM and multiple other replicating loci contribute to Crohn's disease susceptibility. Nat Genet (2007) 13.74
Cbfa1, a candidate gene for cleidocranial dysplasia syndrome, is essential for osteoblast differentiation and bone development. Cell (1997) 13.53
The Composite International Diagnostic Interview. An epidemiologic Instrument suitable for use in conjunction with different diagnostic systems and in different cultures. Arch Gen Psychiatry (1988) 12.83
Genome-wide association study identifies eight loci associated with blood pressure. Nat Genet (2009) 12.44
Genome-wide association study of CNVs in 16,000 cases of eight common diseases and 3,000 shared controls. Nature (2010) 12.27
Genome-wide association of early-onset myocardial infarction with single nucleotide polymorphisms and copy number variants. Nat Genet (2009) 12.19
Large-scale association analysis provides insights into the genetic architecture and pathophysiology of type 2 diabetes. Nat Genet (2012) 11.09
Collaborative genome-wide association analysis supports a role for ANK3 and CACNA1C in bipolar disorder. Nat Genet (2008) 10.49
Meta-analysis of 74,046 individuals identifies 11 new susceptibility loci for Alzheimer's disease. Nat Genet (2013) 9.46
Meta-analysis and imputation refines the association of 15q25 with smoking quantity. Nat Genet (2010) 8.55
Large-scale association analysis identifies new risk loci for coronary artery disease. Nat Genet (2012) 7.59
Mutations involving the transcription factor CBFA1 cause cleidocranial dysplasia. Cell (1997) 7.47
Change in stroke incidence, mortality, case-fatality, severity, and risk factors in Oxfordshire, UK from 1981 to 2004 (Oxford Vascular Study). Lancet (2004) 7.33
A common variant of HMGA2 is associated with adult and childhood height in the general population. Nat Genet (2007) 6.87
QTc-interval abnormalities and psychotropic drug therapy in psychiatric patients. Lancet (2000) 6.78
A polydiagnostic application of operational criteria in studies of psychotic illness. Development and reliability of the OPCRIT system. Arch Gen Psychiatry (1991) 6.74
Rheumatoid arthritis association at 6q23. Nat Genet (2007) 6.71
Localization of type 1 diabetes susceptibility to the MHC class I genes HLA-B and HLA-A. Nature (2007) 6.67
LDL-cholesterol concentrations: a genome-wide association study. Lancet (2008) 6.44
The Genome Sequence DataBase: towards an integrated functional genomics resource. Nucleic Acids Res (1999) 6.20
Microduplications of 16p11.2 are associated with schizophrenia. Nat Genet (2009) 6.13
Alcohol, tobacco and breast cancer--collaborative reanalysis of individual data from 53 epidemiological studies, including 58,515 women with breast cancer and 95,067 women without the disease. Br J Cancer (2002) 5.83
Genome-wide association scan meta-analysis identifies three Loci influencing adiposity and fat distribution. PLoS Genet (2009) 5.81
High rates of schizophrenia in adults with velo-cardio-facial syndrome. Arch Gen Psychiatry (1999) 5.54
New susceptibility locus for coronary artery disease on chromosome 3q22.3. Nat Genet (2009) 5.12
A prospective study of acute cerebrovascular disease in the community: the Oxfordshire Community Stroke Project 1981-86. 1. Methodology, demography and incident cases of first-ever stroke. J Neurol Neurosurg Psychiatry (1988) 4.98
Genetic determinants of ulcerative colitis include the ECM1 locus and five loci implicated in Crohn's disease. Nat Genet (2008) 4.96
De novo CNV analysis implicates specific abnormalities of postsynaptic signalling complexes in the pathogenesis of schizophrenia. Mol Psychiatry (2011) 4.91
Regional variations in the use of common surgical procedures: within and between England and Wales, Canada and the United States of America. Soc Sci Med A (1981) 4.88
Fetal fibronectin in cervical and vaginal secretions as a predictor of preterm delivery. N Engl J Med (1991) 4.68
The compromised host and infection. II. Deep fungal infection. J Infect Dis (1969) 4.63
Genome-wide haplotype association study identifies the SLC22A3-LPAL2-LPA gene cluster as a risk locus for coronary artery disease. Nat Genet (2009) 4.63
Support for the involvement of large copy number variants in the pathogenesis of schizophrenia. Hum Mol Genet (2009) 4.52
High-density genetic mapping identifies new susceptibility loci for rheumatoid arthritis. Nat Genet (2012) 4.46
The strength of the genetic effect. Is there room for an environmental influence in the aetiology of schizophrenia? Br J Psychiatry (1994) 4.40
Genome-wide and fine-resolution association analysis of malaria in West Africa. Nat Genet (2009) 4.30
Genome-wide association study identifies five loci associated with lung function. Nat Genet (2009) 4.10
Genetic variants influencing circulating lipid levels and risk of coronary artery disease. Arterioscler Thromb Vasc Biol (2010) 4.08
Cyclin E controls S phase progression and its down-regulation during Drosophila embryogenesis is required for the arrest of cell proliferation. Cell (1994) 4.07
Screening could seriously damage your health. BMJ (1997) 4.04
Primary structure of human transferrin receptor deduced from the mRNA sequence. Nature (1984) 4.04
The genetics of schizophrenia and bipolar disorder: dissecting psychosis. J Med Genet (2005) 4.02
Use of computerised general practice data for population surveillance: comparative study of influenza data. BMJ (1991) 3.99
Genome-wide association for major depressive disorder: a possible role for the presynaptic protein piccolo. Mol Psychiatry (2008) 3.85
The chemistry and biology of unusual DNA structures adopted by oligopurine.oligopyrimidine sequences. FASEB J (1988) 3.84
Health checks in general practice: another example of inverse care? BMJ (1990) 3.83
Common variants at five new loci associated with early-onset inflammatory bowel disease. Nat Genet (2009) 3.82
Family-based association study of 76 candidate genes in bipolar disorder: BDNF is a potential risk locus. Brain-derived neutrophic factor. Mol Psychiatry (2002) 3.78
Lithium neurotoxicity at normal therapeutic levels. Br J Psychiatry (1993) 3.76
Identification of a vibrio cholerae RTX toxin gene cluster that is tightly linked to the cholera toxin prophage. Proc Natl Acad Sci U S A (1999) 3.75
The bipolar disorder risk allele at CACNA1C also confers risk of recurrent major depression and of schizophrenia. Mol Psychiatry (2009) 3.59
Gene-environment interaction analysis of serotonin system markers with adolescent depression. Mol Psychiatry (2004) 3.54
LRRTM1 on chromosome 2p12 is a maternally suppressed gene that is associated paternally with handedness and schizophrenia. Mol Psychiatry (2007) 3.49
The broad clinical spectrum of bipolar disorder: implications for research and practice. J Psychopharmacol (2008) 3.45
A total audit of preventive procedures in 45 practices caring for 430,000 patients. BMJ (1990) 3.45
Continuous expression of Cbfa1 in nonhypertrophic chondrocytes uncovers its ability to induce hypertrophic chondrocyte differentiation and partially rescues Cbfa1-deficient mice. Genes Dev (2001) 3.43
Methods for estimating the case fatality ratio for a novel, emerging infectious disease. Am J Epidemiol (2005) 3.40
ISYS: a decentralized, component-based approach to the integration of heterogeneous bioinformatics resources. Bioinformatics (2001) 3.36
The moderation by the serotonin transporter gene of environmental adversity in the aetiology of mental illness: review and methodological analysis. Mol Psychiatry (2007) 3.34
Mutations in ATP2A2, encoding a Ca2+ pump, cause Darier disease. Nat Genet (1999) 3.25
Rheumatoid arthritis susceptibility loci at chromosomes 10p15, 12q13 and 22q13. Nat Genet (2008) 3.18