Published in Proc Natl Acad Sci U S A on July 01, 2009
ABC transporters involved in export of cell surface glycoconjugates. Microbiol Mol Biol Rev (2010) 1.50
A remote arene-binding site on prostate specific membrane antigen revealed by antibody-recruiting small molecules. J Am Chem Soc (2010) 1.29
The role of the substrate lipid in processive glycan polymerization by the peptidoglycan glycosyltransferases. J Am Chem Soc (2010) 1.11
Two Arabidopsis proteins synthesize acetylated xylan in vitro. Plant J (2014) 1.02
Synthesis of galactofuranose-based acceptor substrates for the study of the carbohydrate polymerase GlfT2. Bioorg Med Chem (2010) 0.95
A processive carbohydrate polymerase that mediates bifunctional catalysis using a single active site. Biochemistry (2012) 0.91
Monitoring processivity and length control of a carbohydrate polymerase. J Am Chem Soc (2011) 0.91
Fluorosugar chain termination agents as probes of the sequence specificity of a carbohydrate polymerase. J Am Chem Soc (2012) 0.90
Tetrameric structure of the GlfT2 galactofuranosyltransferase reveals a scaffold for the assembly of mycobacterial Arabinogalactan. J Biol Chem (2012) 0.89
Primer preactivation of peptidoglycan polymerases. J Am Chem Soc (2011) 0.87
Staphylococcus aureus and Bacillus subtilis W23 make polyribitol wall teichoic acids using different enzymatic pathways. Chem Biol (2010) 0.86
Isoprenoid phosphonophosphates as glycosyltransferase acceptor substrates. J Am Chem Soc (2014) 0.80
Trapping of intermediates with substrate analog HBOCoA in the polymerizations catalyzed by class III polyhydroxybutyrate (PHB) synthase from Allochromatium vinosum. ACS Chem Biol (2015) 0.78
O-antigen polymerase adopts a distributive mechanism for lipopolysaccharide biosynthesis. Appl Microbiol Biotechnol (2014) 0.77
Twenty Years of Mycobacterial Glycans: Furanosides and Beyond. Acc Chem Res (2016) 0.77
Fidelity and Promiscuity of a Mycobacterial Glycosyltransferase. J Am Chem Soc (2016) 0.76
Comparing Galactan Biosynthesis in Mycobacterium tuberculosis and Corynebacterium diphtheriae. J Biol Chem (2016) 0.75
Lipopolysaccharide endotoxins. Annu Rev Biochem (2001) 18.88
Genes required for mycobacterial growth defined by high density mutagenesis. Mol Microbiol (2003) 16.82
The envelope of mycobacteria. Annu Rev Biochem (1995) 9.33
Biosynthesis and assembly of capsular polysaccharides in Escherichia coli. Annu Rev Biochem (2006) 5.41
Cellulose biosynthesis and function in bacteria. Microbiol Rev (1991) 5.13
Cellulose synthesis in higher plants. Annu Rev Cell Dev Biol (2006) 4.15
Multidomain architecture of beta-glycosyl transferases: implications for mechanism of action. J Bacteriol (1995) 4.00
From bacterial glycogen to starch: understanding the biogenesis of the plant starch granule. Annu Rev Plant Biol (2003) 3.21
Tethering: fragment-based drug discovery. Annu Rev Biophys Biomol Struct (2004) 2.37
Bacterial polysaccharide co-polymerases share a common framework for control of polymer length. Nat Struct Mol Biol (2008) 2.19
Hyaluronan: a multifunctional, megaDalton, stealth molecule. Curr Opin Cell Biol (2000) 2.16
Hyaluronan synthases: a decade-plus of novel glycosyltransferases. J Biol Chem (2007) 2.05
Devising a pathway for hyaluronan catabolism: are we there yet? Glycobiology (2003) 1.91
Cell wall core galactofuran synthesis is essential for growth of mycobacteria. J Bacteriol (2001) 1.90
The glycosyltransferases of Mycobacterium tuberculosis - roles in the synthesis of arabinogalactan, lipoarabinomannan, and other glycoconjugates. Glycobiology (2007) 1.89
A structural basis for processivity. Protein Sci (2001) 1.85
Spanning binding sites on allosteric proteins with polymer-linked ligand dimers. Nature (1998) 1.84
A trivalent system from vancomycin.D-ala-D-Ala with higher affinity than avidin.biotin. Science (1998) 1.69
In vitro synthesis of cellulose II from a cytoplasmic membrane fraction of Acetobacter xylinum. Proc Natl Acad Sci U S A (1987) 1.68
A novel pathway for O-polysaccharide biosynthesis in Salmonella enterica serovar Borreze. J Biol Chem (1996) 1.62
Structural determinants of enzymatic processivity. Biochemistry (1994) 1.61
Parallel-up structure evidences the molecular directionality during biosynthesis of bacterial cellulose. Proc Natl Acad Sci U S A (1997) 1.52
Nontemplate-dependent polymerization processes: polyhydroxyalkanoate synthases as a paradigm. Annu Rev Biochem (2005) 1.45
Intrinsic lipid preferences and kinetic mechanism of Escherichia coli MurG. Biochemistry (2002) 1.44
Comparison of loss of serum resistance by defined lipopolysaccharide mutants and an acapsular mutant of uropathogenic Escherichia coli O75:K5. Infect Immun (1998) 1.36
Galactan biosynthesis in Mycobacterium tuberculosis. Identification of a bifunctional UDP-galactofuranosyltransferase. J Biol Chem (2001) 1.36
Analysis of glycan polymers produced by peptidoglycan glycosyltransferases. J Biol Chem (2007) 1.36
Altering the length of the lipopolysaccharide O antigen has an impact on the interaction of Salmonella enterica serovar Typhimurium with macrophages and complement. J Bacteriol (2006) 1.29
Biosynthesis of the galactan component of the mycobacterial cell wall. J Biol Chem (2000) 1.28
The kinetics and processivity of nucleic acid polymerases. Methods Enzymol (1980) 1.27
On the processivity of polymerases. Ann N Y Acad Sci (1994) 1.26
A continuous spectrophotometric assay for glycosyltransferases. Anal Biochem (1994) 1.25
Structure--function characterization of cellulose synthase: relationship to other glycosyltransferases. Phytochemistry (2001) 1.24
Mechanism of O-antigen distribution in lipopolysaccharide. J Bacteriol (1990) 1.23
The biosynthesis of starch granules. Biomacromolecules (2001) 1.23
Mannan chain length controls lipoglycans signaling via and binding to TLR2. J Immunol (2008) 1.17
Inhibitors of UDP-galactopyranose mutase thwart mycobacterial growth. J Am Chem Soc (2008) 1.12
Isolated peptidoglycan glycosyltransferases from different organisms produce different glycan chain lengths. J Am Chem Soc (2008) 1.09
Control of capsular polysaccharide chain length by UDP-sugar substrate concentrations in Streptococcus pneumoniae. Mol Microbiol (2006) 1.08
Identification of a novel galactosyl transferase involved in biosynthesis of the mycobacterial cell wall. J Bacteriol (2006) 1.05
Expression, purification, and characterization of a galactofuranosyltransferase involved in Mycobacterium tuberculosis arabinogalactan biosynthesis. J Am Chem Soc (2006) 1.05
Galactosyl transferases in mycobacterial cell wall synthesis. J Bacteriol (2007) 1.00
Stop and go: regulation of chain length in the biosynthesis of bacterial polysaccharides. Nat Struct Mol Biol (2008) 0.92
Role of the carbohydrate binding site of the Streptococcus pneumoniae capsular polysaccharide type 3 synthase in the transition from oligosaccharide to polysaccharide synthesis. J Biol Chem (2006) 0.92
Studies on (beta,1-->5) and (beta,1-->6) linked octyl Gal(f) disaccharides as substrates for mycobacterial galactosyltransferase activity. Bioorg Med Chem (2001) 0.87
Development of a coupled spectrophotometric assay for GlfT2, a bifunctional mycobacterial galactofuranosyltransferase. Carbohydr Res (2008) 0.86
Molecular basis for polysialylation: a novel polybasic polysialyltransferase domain (PSTD) of 32 amino acids unique to the alpha 2,8-polysialyltransferases is essential for polysialylation. Glycoconj J (2006) 0.84
Influencing receptor-ligand binding mechanisms with multivalent ligand architecture. J Am Chem Soc (2002) 2.94
Inter-receptor communication through arrays of bacterial chemoreceptors. Nature (2002) 2.61
Trophoblast L-selectin-mediated adhesion at the maternal-fetal interface. Science (2003) 2.40
Selective tumor cell targeting using low-affinity, multivalent interactions. ACS Chem Biol (2007) 2.16
A defined glycosaminoglycan-binding substratum for human pluripotent stem cells. Nat Methods (2010) 2.15
A unique catalytic mechanism for UDP-galactopyranose mutase. Nat Struct Mol Biol (2004) 2.15
Defined substrates for human embryonic stem cell growth identified from surface arrays. ACS Chem Biol (2007) 2.08
Surface plasmon resonance imaging studies of protein-carbohydrate interactions. J Am Chem Soc (2003) 1.96
Chemical probes of bacterial signal transduction reveal that repellents stabilize and attractants destabilize the chemoreceptor array. ACS Chem Biol (2008) 1.69
Activating B cell signaling with defined multivalent ligands. ACS Chem Biol (2007) 1.61
A polymeric domain that promotes cellular internalization. J Am Chem Soc (2008) 1.49
Control of multivalent interactions by binding epitope density. J Am Chem Soc (2002) 1.46
Sialylated multivalent antigens engage CD22 in trans and inhibit B cell activation. Proc Natl Acad Sci U S A (2009) 1.45
Arrays for the combinatorial exploration of cell adhesion. J Am Chem Soc (2004) 1.41
High-throughput discovery of synthetic surfaces that support proliferation of pluripotent cells. J Am Chem Soc (2010) 1.41
Chemical approaches to glycobiology. Annu Rev Biochem (2010) 1.37
Large increases in attractant concentration disrupt the polar localization of bacterial chemoreceptors. Mol Microbiol (2005) 1.27
Conformational changes of glucose/galactose-binding protein illuminated by open, unliganded, and ultra-high-resolution ligand-bound structures. Protein Sci (2007) 1.24
Glycosaminoglycan-binding hydrogels enable mechanical control of human pluripotent stem cell self-renewal. ACS Nano (2012) 1.20
Chemical probes of UDP-galactopyranose mutase. Chem Biol (2006) 1.19
Identification of inhibitors for UDP-galactopyranose mutase. J Am Chem Soc (2004) 1.19
X-ray crystallography reveals a reduced substrate complex of UDP-galactopyranose mutase poised for covalent catalysis by flavin. Biochemistry (2009) 1.18
General synthetic route to cell-permeable block copolymers via ROMP. J Am Chem Soc (2009) 1.14
Site-directed mutagenesis of UDP-galactopyranose mutase reveals a critical role for the active-site, conserved arginine residues. Biochemistry (2007) 1.12
Inhibitors of UDP-galactopyranose mutase thwart mycobacterial growth. J Am Chem Soc (2008) 1.12
Selective immobilization of multivalent ligands for surface plasmon resonance and fluorescence microscopy. Anal Biochem (2002) 1.12
A polymer scaffold for protein oligomerization. J Am Chem Soc (2004) 1.11
Ligand binding and substrate discrimination by UDP-galactopyranose mutase. J Mol Biol (2009) 1.10
Synthesis of fluorogenic polymers for visualizing cellular internalization. Org Lett (2008) 1.03
Bifunctional ligands that target cells displaying the alpha v beta3 integrin. Chembiochem (2007) 1.03
Synthesis and applications of end-labeled neoglycopolymers. Org Lett (2002) 1.03
Solid-phase synthesis of polymers using the ring-opening metathesis polymerization. J Am Chem Soc (2005) 1.01
Synthetic glycoprotein mimics inhibit L-selectin-mediated rolling and promote L-selectin shedding. Chem Biol (2004) 1.00
Affinity-based inhibition of beta-amyloid toxicity. Biochemistry (2002) 0.99
Stereoselective N-glycosylation by Staudinger ligation. Org Lett (2004) 0.98
A strategy for the synthesis of sulfated peptides. Angew Chem Int Ed Engl (2002) 0.96
pentafluorophenyl-phenyl interactions in biphenyl-DNA. Chemistry (2005) 0.95
Synthesis of galactofuranose-based acceptor substrates for the study of the carbohydrate polymerase GlfT2. Bioorg Med Chem (2010) 0.95
Phage display affords peptides that modulate beta-amyloid aggregation. J Am Chem Soc (2006) 0.94
New insights into bacterial chemoreceptor array structure and assembly from electron cryotomography. Biochemistry (2014) 0.94
Spatial control of cell fate using synthetic surfaces to potentiate TGF-beta signaling. Proc Natl Acad Sci U S A (2011) 0.94
Cell aggregation by scaffolded receptor clusters. Chem Biol (2002) 0.91
Synthesis of a multivalent display of a CD22-binding trisaccharide. Carbohydr Res (2002) 0.91
A processive carbohydrate polymerase that mediates bifunctional catalysis using a single active site. Biochemistry (2012) 0.91
Non-carbohydrate inhibitors of the lectin DC-SIGN. J Am Chem Soc (2007) 0.91
Monitoring processivity and length control of a carbohydrate polymerase. J Am Chem Soc (2011) 0.91
Isotope-coded affinity tags with tunable reactivities for protein footprinting. Angew Chem Int Ed Engl (2008) 0.90
Fluorosugar chain termination agents as probes of the sequence specificity of a carbohydrate polymerase. J Am Chem Soc (2012) 0.90
Conserved amplification of chemotactic responses through chemoreceptor interactions. J Bacteriol (2002) 0.90
Contrast agents for magnetic resonance imaging synthesized with ring-opening metathesis polymerization. J Am Chem Soc (2006) 0.89
Protein footprinting in a complex milieu: identifying the interaction surfaces of the chemotaxis adaptor protein CheW. J Mol Biol (2011) 0.89
Solid-phase synthesis of alkanethiols for the preparation of self-assembled monolayers. Langmuir (2007) 0.87
Structure-based design of a periplasmic binding protein antagonist that prevents domain closure. ACS Chem Biol (2009) 0.86
Parallel synthesis of glycomimetic libraries: targeting a C-type lectin. Org Lett (2003) 0.85
UDP-galactopyranose mutase in nematodes. Biochemistry (2013) 0.84
Potent ligands for prokaryotic UDP-galactopyranose mutase that exploit an enzyme subsite. Org Lett (2009) 0.84
Rhamnose glycoconjugates for the recruitment of endogenous anti-carbohydrate antibodies to tumor cells. Chembiochem (2014) 0.83
Noncarbohydrate glycomimetics and glycoprotein surrogates as DC-SIGN antagonists and agonists. ACS Chem Biol (2012) 0.83
Synthesis of lipid-linked arabinofuranose donors for glycosyltransferases. J Org Chem (2013) 0.82
Small-molecule-modified surfaces engage cells through the αvβ3 integrin. ACS Chem Biol (2012) 0.82
Peptide ligands that use a novel binding site to target both TGF-β receptors. Mol Biosyst (2010) 0.82
Synthesis of functionalizable and degradable polymers by ring-opening metathesis polymerization. Angew Chem Int Ed Engl (2013) 0.82
A general glycomimetic strategy yields non-carbohydrate inhibitors of DC-SIGN. Chem Commun (Camb) (2010) 0.81
Unexpected enhancement in biological activity of a GPCR ligand induced by an oligoethylene glycol substituent. J Am Chem Soc (2010) 0.81
Synthetic antigens reveal dynamics of BCR endocytosis during inhibitory signaling. ACS Chem Biol (2013) 0.80
Isoprenoid phosphonophosphates as glycosyltransferase acceptor substrates. J Am Chem Soc (2014) 0.80
Quinoxalinone Inhibitors of the Lectin DC-SIGN. Chem Sci (2011) 0.80
An asymmetric synthesis of L-pyrrolysine. Org Lett (2012) 0.78
ROMP from ROMP: A New Approach to Graft Copolymer Synthesis. Macromolecules (2009) 0.78
Glycomimetic building blocks: a divergent synthesis of epimers of shikimic acid. Org Lett (2011) 0.77
p-Methoxybenzyl ether cleavage by polymer-supported sulfonamides. Org Lett (2002) 0.77
Visualization and characterization of receptor clusters by transmission electron microscopy. Methods Enzymol (2003) 0.76
Decoding signals with chemical biology. ACS Chem Biol (2010) 0.76
Link between chemotactic response to Ni2+ and its adsorption onto the Escherichia coli cell surface. Environ Sci Technol (2005) 0.76
Flow cytometry reveals that multivalent chemoattractants effect swarmer cell dedifferentiation. ACS Chem Biol (2009) 0.75
Classifying chemoreceptors: quantity versus quality. EMBO J (2010) 0.75
Structure-activity relationship, biological, and pharmacological characterization of the proline sulfonamide ACT-462206: a potent, brain-penetrant dual orexin 1/orexin 2 receptor antagonist. ChemMedChem (2014) 0.75
Improved chemical syntheses of 1- and 5-deazariboflavin. J Org Chem (2004) 0.75
ChemRXiv: A Chemistry Preprint Server. ACS Nano (2016) 0.75
Nanoscience and Nanotechnology Cross Borders. ACS Nano (2017) 0.75
A higher degree of difficulty. ACS Chem Biol (2007) 0.75
A symposium in honor of Peter B. Dervan, the 2014 ACS Chemical Biology Lectureship Award Winner. ACS Chem Biol (2014) 0.75
N-acylsulfonamide linker activation by Pd-catalyzed allylation. Org Lett (2006) 0.75
Fostering major breakthroughs. ACS Chem Biol (2006) 0.75